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11361
Characterization of the fungal genus Sphaerellopsis associated with rust fungi: species diversity, host-specificity, biogeography, and in-vitro mycoparasitic events of S. macroconi...
Published 2024-07-01“…However, few detailed studies limit potential BCA development in Sphaerellopsis. Here, we explored the biogeography, host-specificity, and species diversity of Sphaerellopsis and examined the early infection stage of one species, S. macroconidialis, to infer its trophic status. …”
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11362
‘Subtle Instrument of Music’: Translating the Sound and Appearance of Decadence in Wilde’s Salomé
Published 2017-11-01“…The play’s overall concern here is not entirely the notion of passion, but decadence—that is, that fine line between the depraved and the indulgent. …”
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11363
Long-term mindfulness meditation increases occurrence of sensory and attention brain states
Published 2025-01-01“…While many fMRI studies focused on neural activation and functional connectivity during meditation, the impact of long-term MM practice on spontaneous brain activity, and on the expression of resting state networks over time, remains unclear. Here, intrinsic functional network dynamics were compared between experienced meditators and meditation-naïve participants during rest. …”
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11364
Structural basis for the inhibition of coronaviral main proteases by PF-00835231
Published 2024-07-01“…PF-00835231 is a promising inhibitor of SARS-CoV-2 M<sup>pro</sup>. Here, we report the inhibitory potency of PF-00835231 against SARS-CoV-2 M<sup>pro</sup> and seven M<sup>pro</sup> mutants (G15S, M49I, Y54C, K90R, P132H, S46F, and V186F) from SARS-CoV-2 variants. …”
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11365
Distinct neural computations scale the violation of expected reward and emotion in social transgressions
Published 2025-01-01“…Abstract Traditional decision-making models conceptualize humans as adaptive learners utilizing the differences between expected and actual rewards (prediction errors, PEs) to maximize outcomes, but rarely consider the influence of violations of emotional expectations (emotional PEs) and how it differs from reward PEs. Here, we conducted a fMRI experiment (n = 43) using a modified Ultimatum Game to examine how reward and emotional PEs affect punishment decisions in terms of rejecting unfair offers. …”
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11366
Understanding the Dynamics of Sulfur Droplets Formation in Lean‐Electrolyte and Low‐Temperature Lithium–Sulfur Batteries
Published 2025-01-01“…Lean‐electrolyte condition constitutes the prerequisite for high‐energy LSBs, but the insulating sulfur particles hinder capacity utilization, especially at low temperatures. Here, the electrochemical generation of liquid sulfur droplets in the LSB system are studied and elucidate the polysulfide oxidation reaction (SOR) kinetics under different electrolyte/sulfur (E/S) ratios and low‐temperature conditions. …”
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11367
Acute aerobic exercise enhances associative learning in regular exercisers but not in non-regular exercisers
Published 2025-01-01“…As a consequence, no studies have investigated how exercise affects eyeblink conditioning in humans. Here we hypothesize that acute aerobic exercise is associated with improved performance in eyeblink conditioning. …”
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11368
Reduced graphene oxide anchored MnCo2S4 for solid state asymmetric capacitor device
Published 2025-03-01“…A wide working potential range of asymmetric capacitor devices with solid state gel electrolytes have enormous advantages of energy storage devices like high capacity, long life and high-power density. Here, the sandwiched type rGO@MnCo2S4//rGO asymmetric supercapacitor (ASC) electrode was constructed and functioned with a wide potential of 1.6 V. …”
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11369
MT-100, a human Tie2-agonistic antibody, improves penile neurovasculature in diabetic mice via the novel target Srpx2
Published 2025-01-01“…Therefore, strategies for activating the Tie2 signaling pathway have been developed as potential therapies for neurovascular diseases. Here, we developed a human Tie2-agonistic antibody (MT-100) that not only resists Ang-2 antagonism and activates Tie2 signaling but also regulates a novel target, sushi repeat-containing protein X-linked 2 (Srpx2). …”
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11370
Dynamic Monitoring of sTREM-1 and Other Biomarkers in Acute Cholangitis
Published 2020-01-01“…CRP is the best biomarker to suggest infection here. PCT alone is sufficient enough to diagnose sepsis with AC. sTREM-1 is the best biomarker to monitor patients’ response to antimicrobial therapy and biliary drainage.…”
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11371
CFD Modelling of a Centrifugal Compressor with Experimental Validation through Radial Diffuser Static Pressure Measurement
Published 2019-01-01“…The simulation results were also used to investigate the effect of the position (from the blade trailing edge) of the impeller-diffuser interface (a characteristic of the frozen rotor simulation approach). Here an optimal position for the interface was found to be 2% of the blade radius. …”
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11372
Ultrahigh piezoelectric performances of (K,Na)NbO3 based ceramics enabled by structural flexibility and grain orientation
Published 2025-01-01“…Abstract (K,Na)NbO3-based ceramics are deemed among the most promising lead-free piezoelectric materials, though their overall piezoelectric performance still lags behind the mainstream lead-containing counterparts. Here, we achieve an ultrahigh piezoelectric charge coefficient d33 ∼ 807 pC·N−1, along with a high longitudinal electromechanical coupling factor (k33 ∼ 88%) and Curie temperature (Tc ∼ 245 °C) in the (K,Na)(Nb1-x Sb x )O3-Bi0.5Na0.5ZrO3-BiFeO3 (KNN-xSb) system through structural flexibility and grain orientation strategies. …”
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11373
Compact source for quadripartite deterministically entangled optical fields
Published 2025-01-01“…However, realizing an efficient and compact source for multiple quantum users has remained an outstanding challenge, hindering their practical applications. Here, we proposed a compact and feasible scheme to deterministically entangle four spatially separated optical fields, employing only a single NOPA. …”
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11374
The Upregulation of COX2 in Human Degenerated Nucleus Pulposus: The Association of Inflammation with Intervertebral Disc Degeneration
Published 2021-01-01“…We previously found upregulated markers of fibrosis, the late stage of chronic inflammation, in degenerated IVD with a small number of clinical specimens. Here, we aimed to study on a larger scale the association of cyclooxygenase 2 (COX2), an inflammation and/or pain marker, with IVDD. …”
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11375
Increasing Health Burdens Driven by Global Trade Induced Air Pollution
Published 2025-01-01“…Abstract Globalization has led to an increasing geographical separation of primary input, consumption and production, and consequently to a substantial transboundary transfer of air pollution and associated health burdens through international trade. Here, we develop an integrated framework to determine the consumption‐ and income‐based global atmospheric emissions, and quantify the drivers of associated health impacts from 2000 to 2015, and evaluate the impacts of international trade on PM2.5‐related deaths by hypothetical scenarios. …”
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11376
Peripheral signaling pathways contributing to non-histaminergic itch in humans
Published 2023-12-01“…It is unclear how the peripheral nervous system differentiates the signaling of non-histaminergic itch and pain. Methods Here we used psychophysical analysis and microneurography (single nerve fiber recordings) in healthy human volunteers to explore the distinct signaling mechanisms of itch, using the pruritogens β-alanine, BAM 8-22 and cowhage extract. …”
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11377
Strategies to Improve the Quality and Freshness of Human Bone Marrow-Derived Mesenchymal Stem Cells for Neurological Diseases
Published 2021-01-01“…As studies on the traditional characteristics of hBM-MSCs before transplantation into the brain are very limited, omics and machine learning approaches are needed to evaluate cell conditions with indepth and comprehensive analyses. Here, we provide an overview of hBM-MSCs, the application of these cells to various neurological diseases, and improvements in their quality and freshness based on integrated omics after detachment from the culture dish for successful cell therapy.…”
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11378
A modeling study to define guidelines for antigen screening in schools and workplaces to mitigate COVID-19 outbreaks
Published 2025-01-01“…Screening test strategies are characterized by the screening schedule, sensitivity of antigen tests, screening duration, timing of screening initiation, and available tests per person. Results Here, we show that early and frequent screening is the key to maximizing the effectiveness of the screening program. …”
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11379
New probabilistic methods for quantitative climate reconstructions applied to palynological data from Lake Kinneret
Published 2025-02-01“…This is applied to plant-based proxy data from the lake sediment of Lake Kinneret (LK). Here, a priori information on the recent climate in this region and data on arboreal pollen from this lake are used as boundary conditions. …”
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11380
Genomic insights into a multidrug-resistant pandoraea apista clinical isolate carrying blaOXA-153 from China
Published 2025-03-01“…The isolation sources of these 24 strains were predominantly clinical samples, mainly respiratory specimens, with some strains isolated from environmental sources. Conclusion: Here, we present the genome sequence of a P. apista strain carrying the blaOXA-153, marking the first isolation of this strain from a clinical setting in China. …”
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