The use of pigs vocalisation structure to assess the quality of human-pig relationship by Villain, Avelyne S, Guérin, Carole, Tallet, Céline

“…Growing evidence shows that acoustic features of animal vocalisations may be indicators of emotional states. Here, we tested the hypothesis that vocal structure may indicate the quality of HAR. …”
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Rubber intercropping with arboreal and herbaceous species alleviated the global warming potential through the reduction of soil greenhouse gas emissions by Tahir Ashar, Yingying Zhang, Chuan Yang, Wenxian Xu, Muhammad Zeeshan Ul Haq, Hassam Tahir, Hafiz Muhammad Mazhar Abbas, Zhixiang Wu

“…Abstract Agroforestry systems are known to enhance soil health and climate resilience, but their impact on greenhouse gas (GHG) emissions in rubber-based agroforestry systems across diverse configurations is not fully understood. Here, six representative rubber-based agroforestry systems (encompassing rubber trees intercropped with arboreal, shrub, and herbaceous species) were selected based on a preliminary investigation, including Hevea brasiliensis intercropping with Alpinia oxyphylla (AOM), Alpinia katsumadai (AKH), Coffea arabica (CAA), Theobroma cacao (TCA), Cinnamomum cassia (CCA), and Pandanus amaryllifolius (PAR), and a rubber monoculture as control (RM). …”
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Advances in plant male sterility for hybrid seed production: an overview of conditional nuclear male sterile lines and biotechnology-based male sterile systems by Naresh Vasupalli, Naresh Vasupalli, Kanakachari Mogilicherla, Kanakachari Mogilicherla, Vahab Shaik, Vahab Shaik, K. R. S. Sambasiva Rao, Shripad R. Bhat, Xinchun Lin, Xinchun Lin

“…A variety of genetically controlled male sterility/fertility systems starting with cytoplasmic male sterility (CMS), genic male sterility (GMS) including conditional male sterility and transgenic-based male sterility have been developed and deployed for heterosis breeding over the past century. Here we review environment-sensitive genic male sterility (EGMS) and biotechnology-based male sterility systems and describe the underlying molecular mechanisms. …”
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Gnidia glauca- and Plumbago zeylanica-Mediated Synthesis of Novel Copper Nanoparticles as Promising Antidiabetic Agents by Dhiraj A. Jamdade, Dishantsingh Rajpali, Komal A. Joshi, Rohini Kitture, Anuja S. Kulkarni, Vaishali S. Shinde, Jayesh Bellare, Kaushik R. Babiya, Sougata Ghosh

“…Rapid, eco-friendly, and cost-effective one-pot synthesis of copper nanoparticles is reported here using medicinal plants like Gnidia glauca and Plumbago zeylanica. …”
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Volatilization characteristics of high-lead slag and its influence on measurement of physicochemical properties at high temperature by Wang Guohua, Cui Yaru, Yang Ze, Guo Ziliang, Zhao Lv, Li Xiaoming, Zhao Junxue, Tang Wendan

“…Hence, investigating the degree of volatilization and identifying the volatilization mechanism and deviation rules are crucial to improve the accuracy of the measured properties. Here, PbO-FeOx-CaO-SiO2-ZnO slag system was selected as a research subject. …”
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Learning from Demonstrations and Human Evaluative Feedbacks: Handling Sparsity and Imperfection Using Inverse Reinforcement Learning Approach by Nafee Mourad, Ali Ezzeddine, Babak Nadjar Araabi, Majid Nili Ahmadabadi

“…Employing an evaluative feedback, which is easy for teachers to deliver, provides the opportunity to correct the learner’s behavior in an interactive social setting without requiring teachers to know and use their own accurate reward function. Here, we enhance the inverse reinforcement learning (IRL) to estimate the reward function using a mixture of nonoptimal and sparse demonstrations and evaluative feedbacks. …”
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Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana by Sayo Kashiwagi, Isao Kuraoka, Yoshie Fujiwara, Kenichi Hitomi, Quen J. Cheng, Jill O. Fuss, David S. Shin, Chikahide Masutani, John A. Tainer, Fumio Hanaoka, Shigenori Iwai

“…Human DNA polymerase η (HsPolη) plays an important role in translesion synthesis (TLS), which allows for replication past DNA damage such as UV-induced cis-syn cyclobutane pyrimidine dimers (CPDs). Here, we characterized ApPolη from the thermophilic worm Alvinella pompejana, which inhabits deep-sea hydrothermal vent chimneys. …”
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Biological evaluation of novel 5-((1H-indol-3-yl) methyl)-2-(4-chlorobenzyl)-6-phenyl-imidazo[2,1-b][13,4]thiadiazole derivatives as novel BCL-2 specific inhibitors by Shivangi Sharma, Sadashivamurthy Shamanth, Humaira Siddiqua, Laijau Goyary, Kunigal S. Sagar, Susmita Kumari, Divya Sathees, Gudapureddy Radha, Bibha Choudhary, Sathees C. Raghavan, Kempegowda Mantelingu

“…Previously, we reported a novel BCL2 inhibitor, Disarib, which inhibited BCL2 by predominantly binding to its BH1 domain and exhibited platelet-sparing ability like ABT199, the only FDA-approved BCL2 inhibitor. Here, we have synthesized the novel Disarib derivatives where oxindole moiety in Disarib was replaced with indole and evaluated their biological activity. …”
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Evolution of Magnetohydrodynamic Turbulence in the Expanding Solar Wind: Residual Energy and Intermittency by Chen Shi, Nikos Sioulas, Zesen Huang, Marco Velli, Anna Tenerani, Victor Réville

“…The resulting residual energy is primarily distributed in the perpendicular direction, with S _2 ( b ) −  S _2 ( u ) ∝  l _⊥ or equivalently $-{E}_{r}\propto {k}_{\perp }^{-2}$ . Here S _2 ( b ) and S _2 ( u ) are second-order structure functions of magnetic field and velocity respectively. …”
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Heterogeneous Acupuncture Effects of Taixi (KI3) on Functional Connectivity in Healthy Youth and Elder: A Functional MRI Study Using Regional Homogeneity and Large-Scale Functional... by Linlu He, Guangxiang Chen, Ruwen Zheng, Yan Hu, Xiu Chen, Jianghai Ruan

“…Heterogeneous neurological responses of acupuncture between different groups have been proposed by previous studies but rarely studied. The study described here was designed to explore the divergence of acupuncture at Taixi (KI3) on spontaneous activity of brain regions and functional connectivity (FC) between healthy youth and elder with functional magnetic resonance imaging (fMRI). 20 healthy young volunteers and 20 healthy elders underwent 10-minute-resting-state fMRI before acupuncture, and then acupuncture at Taixi (KI3) for 3 minutes; after withdrawing the needles, volunteers underwent a second fMRI scan for 10 minutes. …”
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Managing Friends and Foes: Sanctioning Mutualists in Mixed‐Infection Nodules Trades off With Defense Against Antagonists by Camille E. Wendlandt, Saumik Basu, Angeliqua P. Montoya, Paige Roberts, Justin D. Stewart, Allison B. Coffin, David W. Crowder, E. Toby Kiers, Stephanie S. Porter

“…However, these outcomes may be difficult to achieve simultaneously, since plant defenses activated in response to antagonists can compromise mutualism function, and plant resources allocated to defense may trade off with resources allocated to managing mutualists. Here, we investigate how antagonist attack affects plant ability to manage mutualists with sanctions, in which a plant rewards cooperative mutualists and/or punishes uncooperative mutualists. …”
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The m6A Methylation-Regulated AFF4 Promotes Self-Renewal of Bladder Cancer Stem Cells by Qian Gao, Jin Zheng, Zegui Ni, Pengli Sun, Congcong Yang, Maosheng Cheng, Mingqing Wu, Xiuhong Zhang, Lin Yuan, Yingyin Zhang, Yang Li

“…However, the functions of m6A mRNA modification in bladder cancer stem cells (BCSCs) have not been described. Here, we show that global RNA m6A abundance and the expression of m6A-forming enzyme METTL3 are higher in BCSCs than those in non-CSCs of bladder cancer (BCa) cells. …”
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USP5 stabilizes YTHDF1 to control cancer immune surveillance through mTORC1-mediated phosphorylation by Na Shao, Lei Xi, Yangfan Lv, Muhammad Idris, Lin Zhang, Ya Cao, Jingyi Xiang, Xi Xu, Belinda X. Ong, Qiongyi Zhang, Xu Peng, Xiaoyan Yue, Feng Xu, Chungang Liu

“…A comprehensive understanding of the molecular mechanisms governing YTHDF1 protein stability is pivotal for enhancing clinical response rates and the effectiveness of immune checkpoint blockade in cancer patients. Here, we report that USP5 interacts with YTHDF1, stabilizing it by removing K11-linked polyubiquitination. …”
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Metagenome-assembled microbial genomes (n = 3,448) of the oral microbiomes of Tibetan and Duroc pigs by Hong Hu, Ying Huang, Fuyan Yang, Liangru Ma, Junjie Zhang, Xu Deng, Nan Ma, Kunping Wang, Ye Tao, Qin Lin, Yanfei Li, Xi Bai, Hongbin Pan

“…However, the high host genome content means that few metagenome-based oral microbiomes have been reported. Here, we combined dilution-based metagenomic sequencing and binning approaches to extract the microbial genomes from the oral microbiomes of Tibetan and Duroc pigs. …”
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Elevated SREBP1 accelerates the initiation and growth of pancreatic cancer by targeting SOX9 by Cancan Zhou, Zhengyuan Feng, Weikun Qian, Zeen Zhu, Ruiqi Cao, Qiqi Wang, Wunai Zhang, Rujuan Liu, Shuai Wu, Jie Hao, Zheng Wang, Qingyong Ma, Zheng Wu, Xuqi Li

“…Abstract Pancreatic cancer is a lethal disease with an insidious onset, and little is known about its early molecular events. Here, we found that the sterol regulatory element-binding protein 1 (SREBP1) expression is gradually upregulated during the initiation of pancreatic cancer. …”
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Mgl2+ cDC2s coordinate fungal allergic airway type 2, but not type 17, inflammation in mice by Peter C. Cook, Sheila L. Brown, Emma L. Houlder, Julio Furlong-Silva, Daniel P. Conn, Stefano A. P. Colombo, Syed Baker, Freya R. Svedberg, Gareth Howell, Margherita Bertuzzi, Louis Boon, Joanne E. Konkel, Christopher R. Thornton, Judith E. Allen, Andrew S. MacDonald

“…However, the mechanisms that determine the host response to fungi, which can trigger both type 2 and type 17 inflammation in allergic airway disease, remain unclear. Here we find that CD11c+ DCs and CD4+ T cells are essential for development of both type 2 and type 17 airway inflammation in mice repeatedly exposed to inhaled spores. …”
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Oxidative impact on lipoprotein structure: Insights from dynamic light scattering by Nickolette Kong, Natalia Penaloza, Gustavo Agreda, Angela B. Nguyen, Joseph Gutheinz, Alison Tran, Nhi Nguyen, Tuong Vi Ho, Ana Marin, Birgit Mellis, Richa Chandra

“…Clinicians often rely on indirect calculations of low-density lipoprotein (LDL) as a primary diagnostic indicator, which can oversimplify and overlook the complex changes in lipoprotein structure and function and therefore the complex etiology of CVD. Here it is demonstrated that dynamic light scattering (DLS) is sensitive and effective at measuring variation in lipoprotein size distributions following oxidative damage caused by peroxidation and nitration—two common physiological processes that play dual roles in both normal and pathogenic states. …”
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Utilization of MS 222 in Transport of Catfish (Pangasius sutchi) Seed by Harton Arfah, Eddy Supriyono

“…The experimental design used here was factorial design 3x5 with 3 repetitions.  …”
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Genome-wide analysis of Smad and Schnurri transcription factors in C. elegans demonstrates widespread interaction and a function in collagen secretion by Mehul Vora, Jonathan Dietz, Zachary Wing, Karen George, Jun Kelly Liu, Christopher Rongo, Cathy Savage-Dunn

“…In C. elegans, the BMP2/4 ortholog DBL-1 regulates multiple biological functions, including body size, via a canonical receptor-Smad signaling cascade. Here, we identify functional binding sites for SMA-3/Smad and its transcriptional partner SMA-9/Schnurri based on ChIP-seq peaks (identified by modEncode) and expression differences of nearby genes identified from RNA-seq analysis of corresponding mutants. …”
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Evaluation of Active Intraoperative Nerve Monitoring in Severe Developmental Dysplasia of the Hip Patients Undergoing Total Hip Arthroplasty by Alireza Manafi Rasi, MD, Sina Afzal, Dr., MD, Mojtaba Baroutkoub, MD, Hasan Shakiba, MD, Pooya Kalani, MD, Mehdi Tavassoli, MD, Reza Zarei, MD

“…Background: Total hip arthroplasty (THA) stands as the standard treatment in neglected developmental dysplasia of the hip (DDH), and its application in severe cases may be linked to debilitating outcomes, including nerve damage. Here, we aimed to report the results of intraoperative nerve monitoring (IONM) via an active method. …”
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