Reprogramming the tumor immune microenvironment using engineered dual-drug loaded Salmonella by Dinh-Huy Nguyen, Sung-Hwan You, Hien Thi-Thu Ngo, Khuynh Van Nguyen, Khang Vuong Tran, Tan-Huy Chu, So-young Kim, Sang-Jun Ha, Yeongjin Hong, Jung-Joon Min

“…These side-effects can be overcome by using a tumor-specific delivery system. Here, we report a method of targeted immunotherapy using an attenuated Salmonella typhimurium (SAM-FC) engineered to release dual payloads: cytolysin A (ClyA), a cytolytic anti-cancer agent, and Vibrio vulnificus flagellin B (FlaB), a potent inducer of anti-tumor innate immunity. …”
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Religion and politics of belonging in digital times: youth religiosity in focus by Astrid Mattes, Miriam Haselbacher, Katharina Limacher, Christoph Novak

“…It concerns and involves individuals and their identifications. Here, digital spaces, as increasingly relevant spaces of public exchange, provide new terms for identity work. …”
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The mirror preference test: A reverse translational approach to study anomalous subjective experience in rats by Daria Chestnykh, Liubov S. Kalinichenko, Stephan von Hörsten, Johannes Kornhuber, Christian P. Müller

“…To address this, we developed a task to evaluate anomalous subjective experiences in rats using a Mirror-Preference test. Here we demonstrate that naive rats show a preference for a mirror chamber, which was followed by significant habituation over a series of trials. …”
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The protein circPETH-147aa regulates metabolic reprogramming in hepatocellular carcinoma cells to remodel immunosuppressive microenvironment by Tian Lan, Fengwei Gao, Yunshi Cai, Yinghao Lv, Jiang Zhu, Hu Liu, Sinan Xie, Haifeng Wan, Haorong He, Kunlin Xie, Chang Liu, Hong Wu

“…Abstract Metabolic reprogramming fuels cancer cell metastasis and remodels the immunosuppressive tumor microenvironment (TME). We report here that circPETH, a circular RNA (circRNA) transported via extracellular vesicles (EVs) from tumor-associated macrophages (TAMs) to hepatocellular carcinoma (HCC) cells, facilitates glycolysis and metastasis in recipient HCC cells. …”
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Spline approximation of multivalued functions in linear structures routing by D. A. Karpov, V. I. Struchenkov

“…Here, in contrast to widely use polynomial splines, the repeating element is the link “segment of a straight line + arc of a circle” or “segment of a straight line + arc of a clothoid + arc of a circle + arc of a clothoid.” …”
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Machine learning Hubbard parameters with equivariant neural networks by Martin Uhrin, Austin Zadoks, Luca Binci, Nicola Marzari, Iurii Timrov

“…We target here the prediction of Hubbard parameters computed self-consistently with iterative linear-response calculations, as implemented in density-functional perturbation theory (DFPT), and structural relaxations. …”
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Le mouvement de désinvestissement des énergies fossiles : une nouvelle phase de mobilisation pour le climat ? by Fanny Lajarthe, Edwin Zaccai

“…The recent arrival of the movement in Europe raises questions about the difficulties related to the diffusion process from one context to another. We take here the example of the shy spreading of the movement in Belgium in order to illustrate how national conditions necessarily shape the movement strategies.…”
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Book reviews: Rethinking residential child care: Positive perspectives. Mark Smith, Bristol, Policy Press, 2009. 209pp, ISBN 978-1 -86134-908-8 by Pat Petrie

“…There is a joke in which a stranger asks a local person for directions, only to be told, "Well, if I were you, I wouldn't start from here." And to me that feels uncomfortably close to the difficulties to be faced in rethinking residential child care, which is one of the trickier problems for social policy in the UK today. …”

Case studies in numerical simulation of crack trajectories in brittle materials by H. Jasarevic, S. Gagula

“…Case studies on numerical simulation ofexperimentally observed crack trajectories in sandstone (discs tested in indirect tensile strength test) andconcrete (compact tension specimens tested in the quasi-static splitting tensile test) are presented here.…”
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Giant Primary Retroperitoneal Teratoma in an Adult: A Case Report by Poonam Mathur, Miguel A. Lopez-Viego, Myron Howell

“…Retroperitoneal teratomas are rare and present challenging management options. We report here the case of a histologically unusual retroperitoneal tumor detected on computed tomography during the workup of abdominal pain in a 32-year-old male. …”
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Pulmonary mucormycosis in kidney transplant patient by Mona Jha, Shailly Deshawar, Nikhil Kirar, Manas Kamal Sen

“…Early diagnosis and treatment should be made due to the fierce behavior of this infection and the high chances of dissemination. Here, we present a case of pulmonary mucormycosis in a diabetic and hypertensive patient who had a renal transplant and presented with cough, hemoptysis, and shortness of breath. …”
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La traversée des cols alpins : analyse d’une poétique de la liminalité by Samia OUNOUGHI

“…In exploring these novels using both pragmatics and human geography we meanwhile seek to show how much characters contribute to the framing of the mountains. Thus, poetics is here conceived as the very material the mountains are made of and it defines them as spaces in movement.…”
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On a Periodic System of Difference Equations by Stevo Stević, Josef Diblík, Bratislav Iričanin, Zdeněk Šmarda

“…Here we give a very short and elegant proof of an extension of two recent results on global periodicity of two systems of difference equations in a work of Elsayed et al. 2012.…”
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Cytokines as cellular communicators by R. Debets, H. F. J. Savelkoul

“…Cytokines and their receptors are involved in the pathophysiology of many diseases. Here we present a detailed review on cytokines, receptors and signalling routes, and show that one important lesson from cytokine biology is the complex and diverse regulation of cytokine activity. …”
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Climate data for climate action by Ulf Büntgen, Mirek Trnka, Mike Hulme, Jan Esper

“…Political instability and geopolitical tension, together with rising nationalism, bureaucracy and economic pressure, increasingly challenge free access to and exchange of scientific data (both physical and digital), knowledge transfer (within and beyond academia), and research campaigns (of national and international teams around the world). Here, we call for an open-data convention implemented by universities and institutions, academies and organisations, journals and editors, as well as funding agencies and national administrations.…”
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Faire pays dans un cyberespace : le cas des Haïtiens en Île-de-France by Rébecca Cadeau

“…The study of the uses of dedicated applications and socio-digital networks by diaspora associations, allows us to analyze the ways in which Haitians make themselves present « here », « there » and « elsewhere », in order to continue « making their country » in the « territories of dispersal ». …”
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Art Spiegelman : de l’outrenoir à l’outrebiographie dans In the Shadow of No Towers by Yves DAVO

“…After a study comparing Art Spiegelman’s cover album with the “outrenoir” concept theorized by the French painter Pierre Soulages, this article will aim at redefining Spiegelman’s autobiography as “outrebiography,” understood here as going beyond the bounds of a mere testimony of the self towards the biography of a shared experience. …”
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Dissipative Effect and Tunneling Time by Samyadeb Bhattacharya, Sisir Roy

“…The quantum Langevin equation has been studied for dissipative system using the approach of Ford et al. Here, we have considered the inverted harmonic oscillator potential and calculated the effect of dissipation on tunneling time, group delay, and the self-interference term. …”
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An unusual case of acute chest pain by Ananda Datta, Raghavendrun Sivasankar

“…Uncommonly, cough-induced fractures have been reported in healthy young individuals. Here, we present a case of a 32-year-old healthy man who suffered a fracture of the left seventh rib following a bout of violent coughing.…”
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Sebaceous carcinoma with apocrine differentiation arising in a known case of basal cell carcinoma: A rare entity by Manisha Ahuja, Shramana Mandal, Meeta Singh, Nita Khurana, Padam Singh Bhandari

“…Apocrine differentiation in sebaceous carcinomas is rare but has been reported in the literature. Here, we present a case of sebaceous carcinoma with apocrine differentiation in a 62-year- old female who was a diagnosed case of basal cell carinoma.…”
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