Optimizing fully-efficient two-stage models for genomic selection using open-source software by Javier Fernández-González, Julio Isidro y Sánchez

“…However, unweighted (UNW) two-stage models assume independent errors among adjusted means, neglecting correlations among estimation errors. Here, we show that fully-efficient two-stage models perform similarly to UNW models for randomized complete block designs but substantially better for augmented designs. …”
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A reproducible representation of healthy tibiofemoral kinematics during stair descent using REFRAME – part I: REFRAME foundations and validation by Ariana Ortigas-Vásquez, William R. Taylor, Barbara Postolka, Pascal Schütz, Allan Maas, Matthias Woiczinski, Thomas M. Grupp, Adrian Sauer

“…Consequently, for consistent interpretation of joint motion (especially direct comparison) to be possible, differences in local frame position and orientation must first be addressed. Here, building on previous work that introduced a frame orientation optimisation method and demonstrated its potential to induce convergence towards a consistent kinematic signal, we present the REference FRame Alignment MEthod (REFRAME) that addresses both rotational and translational kinematics, is validated here for a healthy tibiofemoral joint, and allows flexible selection of optimisation criteria to fittingly address specific research questions. …”
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Reprogramming the tumor immune microenvironment using engineered dual-drug loaded Salmonella by Dinh-Huy Nguyen, Sung-Hwan You, Hien Thi-Thu Ngo, Khuynh Van Nguyen, Khang Vuong Tran, Tan-Huy Chu, So-young Kim, Sang-Jun Ha, Yeongjin Hong, Jung-Joon Min

“…These side-effects can be overcome by using a tumor-specific delivery system. Here, we report a method of targeted immunotherapy using an attenuated Salmonella typhimurium (SAM-FC) engineered to release dual payloads: cytolysin A (ClyA), a cytolytic anti-cancer agent, and Vibrio vulnificus flagellin B (FlaB), a potent inducer of anti-tumor innate immunity. …”
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Religion and politics of belonging in digital times: youth religiosity in focus by Astrid Mattes, Miriam Haselbacher, Katharina Limacher, Christoph Novak

“…It concerns and involves individuals and their identifications. Here, digital spaces, as increasingly relevant spaces of public exchange, provide new terms for identity work. …”
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The mirror preference test: A reverse translational approach to study anomalous subjective experience in rats by Daria Chestnykh, Liubov S. Kalinichenko, Stephan von Hörsten, Johannes Kornhuber, Christian P. Müller

“…To address this, we developed a task to evaluate anomalous subjective experiences in rats using a Mirror-Preference test. Here we demonstrate that naive rats show a preference for a mirror chamber, which was followed by significant habituation over a series of trials. …”
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Spline approximation of multivalued functions in linear structures routing by D. A. Karpov, V. I. Struchenkov

“…Here, in contrast to widely use polynomial splines, the repeating element is the link “segment of a straight line + arc of a circle” or “segment of a straight line + arc of a clothoid + arc of a circle + arc of a clothoid.” …”
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Machine learning Hubbard parameters with equivariant neural networks by Martin Uhrin, Austin Zadoks, Luca Binci, Nicola Marzari, Iurii Timrov

“…We target here the prediction of Hubbard parameters computed self-consistently with iterative linear-response calculations, as implemented in density-functional perturbation theory (DFPT), and structural relaxations. …”
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Giant Primary Retroperitoneal Teratoma in an Adult: A Case Report by Poonam Mathur, Miguel A. Lopez-Viego, Myron Howell

“…Retroperitoneal teratomas are rare and present challenging management options. We report here the case of a histologically unusual retroperitoneal tumor detected on computed tomography during the workup of abdominal pain in a 32-year-old male. …”
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On a Periodic System of Difference Equations by Stevo Stević, Josef Diblík, Bratislav Iričanin, Zdeněk Šmarda

“…Here we give a very short and elegant proof of an extension of two recent results on global periodicity of two systems of difference equations in a work of Elsayed et al. 2012.…”
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Cytokines as cellular communicators by R. Debets, H. F. J. Savelkoul

“…Cytokines and their receptors are involved in the pathophysiology of many diseases. Here we present a detailed review on cytokines, receptors and signalling routes, and show that one important lesson from cytokine biology is the complex and diverse regulation of cytokine activity. …”
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Climate data for climate action by Ulf Büntgen, Mirek Trnka, Mike Hulme, Jan Esper

“…Political instability and geopolitical tension, together with rising nationalism, bureaucracy and economic pressure, increasingly challenge free access to and exchange of scientific data (both physical and digital), knowledge transfer (within and beyond academia), and research campaigns (of national and international teams around the world). Here, we call for an open-data convention implemented by universities and institutions, academies and organisations, journals and editors, as well as funding agencies and national administrations.…”
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Faire pays dans un cyberespace : le cas des Haïtiens en Île-de-France by Rébecca Cadeau

“…The study of the uses of dedicated applications and socio-digital networks by diaspora associations, allows us to analyze the ways in which Haitians make themselves present « here », « there » and « elsewhere », in order to continue « making their country » in the « territories of dispersal ». …”
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Dissipative Effect and Tunneling Time by Samyadeb Bhattacharya, Sisir Roy

“…The quantum Langevin equation has been studied for dissipative system using the approach of Ford et al. Here, we have considered the inverted harmonic oscillator potential and calculated the effect of dissipation on tunneling time, group delay, and the self-interference term. …”
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An unusual case of acute chest pain by Ananda Datta, Raghavendrun Sivasankar

“…Uncommonly, cough-induced fractures have been reported in healthy young individuals. Here, we present a case of a 32-year-old healthy man who suffered a fracture of the left seventh rib following a bout of violent coughing.…”
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Sebaceous carcinoma with apocrine differentiation arising in a known case of basal cell carcinoma: A rare entity by Manisha Ahuja, Shramana Mandal, Meeta Singh, Nita Khurana, Padam Singh Bhandari

“…Apocrine differentiation in sebaceous carcinomas is rare but has been reported in the literature. Here, we present a case of sebaceous carcinoma with apocrine differentiation in a 62-year- old female who was a diagnosed case of basal cell carinoma.…”
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A Beginner’s Guide to Water Management — Symbols, Abbreviations & Conversion Factors by Florida LAKEWATCH

“…Much of this information is typically only available by searching numerous publications, but we have assembled it here under one cover for quick reference. This document is CIR105, is the fifth of a series of information circulars dedicated to familiarizing citizens with the language and techniques used by those involved in water management, of the Fisheries and Aquatic Sciences Department, UF/IFAS Extension. © April 2002, 2nd Edition. …”
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Indicateurs et cartographie dynamique du bruit, un instrument de reconfiguration des politiques publiques ? by Philippe Zittoun

“…The assumption defended here is that indicator appears like a translator and an arranger: A translator because it makes it possible to transform a complex phenomenon into public problem; an arranger since it proposes to attach this problem at victims, a guilty, a legitimate solution to solve it and actors to use it.…”
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Vers une géographie du droit ? Pistes de réflexion by Patrick Forest

“…In this context, he places the present issue, not as a continuity of the introduced reflections but rather as a renewal of these perspectives because firstly, the essentially exploratory objective of his work, if it allowed readers to discover the disciplines interface, and, secondly, the main objective to find a name for this approach, are here overtaken. As this is a "new" conception (or rather renewed) of the thought, quasi-unknown in France, its "testimony" places the originality and the interest of the combined approach between law and geography.…”
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Thermodynamic matrix exponentials and thermodynamic parallelism by Samuel Duffield, Maxwell Aifer, Gavin Crooks, Thomas Ahle, Patrick J. Coles

“…It was recently shown that certain linear algebra problems can be solved thermodynamically, leading to a speedup scaling with the matrix dimension. Here, we provide a thermodynamic algorithm for exponentiating a real matrix. …”
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Reproducibility and transparency: what’s going on and how can we help

“…However, the opinions on the causes of the reproducibility “crisis” and how we all can help vary amongst fields as well as individual scientists. Here, we talk to experts from different fields of science to get their insights on this endemic issue. …”
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