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581
Research Progress on the Mechanism of Acupuncture Treatment for Nonalcoholic Fatty Liver Disease
Published 2022-01-01“…Nonalcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease worldwide, ranging from simple steatosis and nonalcoholic steatohepatitis to fibrosis, cirrhosis, and hepatocellular carcinoma. Acupuncture is a long-established treatment in traditional Chinese medicine. …”
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582
Forgettable in the care of liver cirrhosis: the unseen culprits of progression from bad to worse
Published 2024-03-01“…The lack of disease-specific nutritional guidance, the prevalent sedentary lifestyle among patients, and insufficient screening for hepatocellular carcinoma, oesophageal varices, sarcopaenia, minimal hepatic encephalopathy, and diabetes mellitus, along with fibrosis progression and cirrhosis decompensation, can add further complexities. …”
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583
NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis
Published 2010-01-01“…Hepatocellular carcinoma (HCC) is the third largest cause of cancer deaths worldwide. …”
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584
Diagnostics of hepatocellular cancer: state-of-the-art
Published 2014-10-01“…To present features of hepatocellular carcinoma (HCC) diagnostics.Key points. Factors of HCC development, principles of screening diagnostics in risk group are discussed. …”
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585
Prioritization of potential pharmacological targets for the development of anti-hepatocarcinoma drugs modulating the extrinsic apoptosis pathway: the reconstruction and analysis...
Published 2023-12-01“…Hepatocellular carcinoma (HCC) is a common severe type of liver cancer characterized by an extremely aggressive course and low survival rates. …”
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586
The Role of Eosinophils in Liver DiseaseSummary
Published 2025-01-01“…Although eosinophils are infrequently observed within the liver during periods of homeostasis, they are recruited to the liver in various liver diseases, including liver parasitosis, acute liver injury, autoimmune liver disease, and hepatocellular carcinoma. Furthermore, eosinophils have demonstrated the capacity to promote liver regeneration. …”
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587
One-Pot Synthesis of Novel Furochromone and Oxazocine Derivatives as Promising Antitumor Agents with Their Molecular Docking Studies
Published 2020-01-01“…The obtained derivatives of novel furochromone and oxazocine derivatives were evaluated as promising antitumor agents against panel of two human cell lines, hepatocellular carcinoma (HEPG2) and breast carcinoma (MCF7). …”
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588
Surviving Emphysematous Gastritis after Hepatectomy
Published 2013-01-01“…We are reporting a middle-aged Chinese male with hepatitis B virus related hepatocellular carcinoma. He underwent partial hepatectomy and was diagnosed with emphysematous gastritis 4 days after index operation. …”
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589
Olfm4 Is Highly Expressed in HCC Patients and as a Biomarker and Therapeutic Target for HCC
Published 2021-01-01“…Hepatocellular carcinoma (HCC) is one of the primary types of cancer that claims many lives worldwide, and its incidence continues to increase. …”
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590
Disruption of tumor-intrinsic PGAM5 increases anti-PD-1 efficacy through the CCL2 signaling pathway
Published 2025-01-01“…Background Immunosuppressive phenotype compromised immunotherapy efficacy of hepatocellular carcinoma. Tumor cells intrinsic mitochondria dynamics could pass effects on the extracellular microenvironment through mtDNA stress. …”
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591
Kadukkai maathirai (Indian herbal drug) prevents hepatocellular cancer progression by enhancing GSTM1 expression and modulating β catenin transcription: in-silico and in-vivo study...
Published 2024-10-01“…Background Hepatocellular carcinoma (HCC) is an aggressive malignancy with poor clinical outcomes. …”
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592
Increased Porphyrins in Primary Liver Cancer Mainly Reflect a Parallel Liver Disease
Published 2009-01-01“…To evaluate the role of an underlying liver disorder we analyzed porphyrins in patients with hepatocellular carcinoma (HCC) (n=65), cholangiocellular carcinoma (n=3), or suspected PLC, which turned out to be metastases (n=18) or a benign disorder (n=11). …”
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593
Fibrolamellar Carcinoma: 2012 Update
Published 2012-01-01“…Fibrolamellar carcinomas are not indolent tumors, but have an overall better prognosis than typical hepatocellular carcinomas, in part because of the younger age at presentation and the lack of cirrhosis. …”
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594
Recent Advances in Antiviral Therapy for Chronic Hepatitis C
Published 2016-01-01“…Chronic infection induces continuous inflammation in the liver, progression of hepatic fibrosis, eventual cirrhosis, and possible hepatocellular carcinoma. Eradication of the virus is one of the most important treatment aims. …”
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595
Autoimmune hepatitis with abnormally high level of serum alpha-fetoprotein (Clinical case)
Published 2010-02-01“…Manifestations of AIH, at first glance were typical, accompanied by over 200-fold elevation of serum concentration of AFP that required differential diagnostics with hepatocellular carcinoma. Achievement of immunosuppressor-induced remission resulted in normalization of AFP level.Conclusion. …”
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596
Oxidative stress in viral hepatitis
Published 2024-04-01“…This damage manifests as lipid peroxidation, DNA damage, and protein oxidation, which in turn promote hepatic inflammation, fibrosis, and hepatocellular carcinoma. Furthermore, OS has been implicated in the resistance to antiviral therapy observed in some patients. …”
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597
Reenvisioning Traditional to Regenerative Therapeutic Advances in Managing Nonalcoholic Fatty Liver Disease in Diabetes Mellitus
Published 2021-01-01“…Clinically, it has also been revealed that the existence of nonalcoholic fatty liver disease (NAFLD) enhances the incidence of type 2 diabetes mellitus (T2DM), while T2DM exacerbates NAFLD to extremely severe forms of steatohepatitis, cirrhosis, and hepatocellular carcinoma. This implies the coexistence and bidirectional nature of NAFLD and T2DM, which function synergistically to drive adverse consequences in clinical practice. …”
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598
Sorafenib-Induced Liver Failure: A Case Report and Review of the Literature
Published 2011-01-01“…In patients with hepatocellular carcinoma characterized by vascular invasion and/or extrahepatic disease, Sorafenib is considered treatment of choice. …”
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599
Motion – The Available Treatments for Hepatitis C Are Cost Effective: Arguments against the Motion
Published 2002-01-01“…Available cohortbased studies suggest that only a relative minority of patients develop significant liver disease, such as cirrhosis and/or hepatocellular carcinoma. Other studies, mostly conducted based on referral patients with established disease, portray much more serious consequences of HCV infection. …”
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600
Transitioning to Highly Effective Therapies for the Treatment of Chronic Hepatitis C Virus Infection: A Policy Statement and Implementation Guideline
Published 2014-01-01“…Chronic hepatitis C virus (HCV) infection increases all-cause mortality, rates of cirrhosis, hepatocellular carcinoma, liver transplantation and overall health care utilization. …”
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