Impact of interferon-free regimens in patients with chronic HCV and successfully ablated HCC by Amr Maged Mahmoud Rasheed, Maissa E. L. Raziky, Mohammad El Sayed, Mai Mehrez, Gamal Esmat

“…Abstract Background Hepatocellular carcinoma (HCC) ranks sixth amongst all cancers and is the 2nd top cause of mortality attributable to cancer. …”
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Predictors of intrahepatic cholangiocarcinoma recurrence after surgical treatment by E. V. Kondratyev, A. D. Smirnova, G. G. Karmazanovsky, A. S. Tyan, N. N. Britskaya, M. G. Efanov, B. N. Gurmikov

“…We identified CT signs that allow differential diagnosis of ICC with hepatocellular carcinoma and colorectal cancer metastases. …”
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Pan-Cancer Analysis of Disulfidptosis-Related Genes Affecting Prognosis and Tumor Microenvironment by Jingyang SUN, Rongxuan JIANG, Liren HOU, Huanhuan DONG, Yihan LIN, Niuniu DONG, Guangjian ZHANG, Yanpeng ZHANG

“…Experimental validation demonstrated the overall higher expression levels of GYS1 and NCKAP1 than normal cells in lung adenocarcinoma, colon adenocarcinoma, esophageal squamous carcinoma, and hepatocellular carcinoma (P<0.05). ConclusionPan-cancer analysis of DRGs indicates that DRGs may serve as important biomarkers for the diagnosis and prognosis of renal clear-cell carcinoma, lung adenocarcinoma, and hepatocellular carcinoma.…”
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Desmoplastic Small Round Cell Tumor, a “Floating Island” Pattern in Pleural Fluid Cytology: A Case Report and Review of the Literature by Hui Zhu, Emily Marie McMeekin, Charles D. Sturgis

“…We report an interesting case of DSRCT involving a pleural effusion with a “floating island” pattern that has been described in hepatocellular carcinoma, renal cell carcinoma, and adrenal cortical carcinoma. …”
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Liver Cirrhosis: A Seven Year Follow-Up by TS Paul Tran, S Victor Feinman, Barnet Berris

“…One patient died of hepatocellular carcinoma. Patients who survived seven years had fewer complications when seen in 1981 than those who died during this period (P<0.025). …”
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In vitro antitumor effects of methanolic extracts of three Ganoderema mushrooms by Elshahat A. Toson, Amira A. El-Fallal, Marwa A. Oransa, Hoda M. El-Gharabawy

“…These results may encourage speculation about their possible use for the therapeutic management of hepatocellular carcinoma and breast ductal carcinoma after further investigation.…”
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Efficacy and safety of tenofovir and entecavir in patients with chronic hepatitis B-related cirrhosis: a systematic review and meta-analysis by Lu Cao, Li Li, Lixing Yang, Nan Zhou, Yu Zhang

“…The meta-analysis revealed that tenofovir significantly reduced the cumulative incidence of hepatocellular carcinoma and cumulative mortality compared to entecavir in East Asian popupation, while in non East Asian populations, the two groups are roughly equivalent. …”
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Thrombophilic Genetic Factors PAI-1, MTHFRC677T, V Leiden 506Q, and Prothrombin 20210A in Noncirrhotic Portal Vein Thrombosis and Budd-Chiari Syndrome in a Caucasian Population by Mario D’Amico, Pietro Sammarco, Linda Pasta

“…Our study shows an important role of PAI-14G-4G and MTHFR677TT in abdominal thrombosis without liver cirrhosis or hepatocellular carcinoma.…”
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Hepatitis B Learning Needs Assessment of Family Medicine Trainees in Canada: Results of a Nationwide Survey by Justina J Sam, E Jenny Heathcote, David KH Wong, Douglas L Wooster, Hemant Shah

“…BACKGROUND: An estimated 350 million people worldwide have chronic hepatitis B (CHB), which is a major cause of cirrhosis and hepatocellular carcinoma.…”
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Liver transplantation in glycogen storage disease type III: A case‐series by Simon Gay, Adrien Bigot, Louis d'Alteroche, Fanny Dujardin, Gaëlle Fromont‐Hankard, Nathalie Tressel, Ephrem Salame, François Maillot

“…Hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC) are common complications in older patients. …”
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Management of Solitary 1 cm to 2 cm Liver Nodules in Patients with Compensated Cirrhosis: A Decision Analysis by Karen E Bremner, Ahmed M Bayoumi, Morris Sherman, Murray D Krahn

“…OBJECTIVES: Current guidelines, based on expert opinion, recommend that suspected 1 cm to 2 cm hepatocellular carcinoma (HCC) detected on screening be biopsied and, if positive, treated (eg, resection or transplantation). …”
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Patients with Chronic Hepatitis C - Who Should Not Be Treated? by Andreas Schüler, Michael Peter Manns

“…The decision to treat a patient with chronic hepatitis C (CHC) is based on what is known about the risk factors for developing liver cirrhosis or hepatocellular carcinoma, as well as on conditions that contraindicate therapy or impair therapy effectiveness. …”
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Antiviral therapy and regression of liver fibrosis at chronic hepatitis B by D. T. Abdurakhmanov

“…Decrease of severity of fibrosis (for prophylaxis of liver cirrhosis and hepatocellular carcinoma development) is one of the basic criteria of efficacy of treatment of chronic liver diseases. …”
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The Role of Iron in the Pathophysiology and Treatment of Chronic Hepatitis C by Leslie Price, Kris V Kowdley

“…Hepatic iron depletion has been postulated to decrease the risk of hepatocellular carcinoma in patients with cirrhosis due to chronic hepatitis C. …”
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Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression by Mingzhen Zhou, Ziyan Zhou, Lina Hu, Sidong Chen, Fanyan Meng, Jun Chen, Jie Shen

“…Abstract Objectives GPC3 has been recognized as a promising target for immunotherapy in hepatocellular carcinoma (HCC). However, the GPC3-targeted immunotherapies have shown limited therapeutic efficacy. …”
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Burden of Disease and Cost of Chronic Hepatitis C Virus Infection in Canada by Robert P Myers, Mel Krajden, Marc Bilodeau, Kelly Kaita, Paul Marotta, Kevork Peltekian, Alnoor Ramji, Chris Estes, Homie Razavi, Morris Sherman

“…BACKGROUND: Chronic infection with hepatitis C virus (HCV) is a major cause of cirrhosis, hepatocellular carcinoma and liver transplantation.…”
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HCC Heterogeneity: Molecular Pathogenesis and Clinical Implications by Emilia Fransvea, Angelo Paradiso, Salvatore Antonaci, Gianluigi Giannelli

“…Background: Hepatocellular carcinoma (HCC) poses a major challenge because of the extreme variability of the clinical outcome, which makes it difficult to properly stage the disease and thereby estimate the prognosis. …”
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Synthesis and Biological Evaluation of 2,4-Diaminoquinazolines as Potential Antitumor Agents by Mohammad A. Alassaf, Khalid B. Selim, Magda N. A. Nasr

“…Among the synthesized compounds, 4c and 5b with 4-substitution at the phenyl ring were found to have the highest inhibitory effects against breast adenocarcinoma (MCF-7), colon cancer (HCT-116), hepatocellular carcinoma (HePG-2), and human skin cancer (HFB4). …”
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TLRs, Alcohol, HCV, and Tumorigenesis by Keigo Machida

“…Chronic liver damage caused by viral infection, alcohol, or obesity can result in increased risk for hepatocellular carcinoma (HCC). Ample epidemiological evidence suggests that there is a strong synergism between hepatitis C virus (HCV) and alcoholic liver diseases (ALD). …”
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From the Cytoplasm into the Nucleus—Hepatitis B Virus Travel and Genome Repair by Johan Ringlander, Gustaf E. Rydell, Michael Kann

“…HBV is part of the hepadnaviridae family and one of the primary causes of acute and chronic liver infections, leading to conditions such as cirrhosis and hepatocellular carcinoma (HCC). Understanding the intracellular transport and genome repair mechanisms of HBV is crucial for developing new drugs, which—in combination with immune modulators—may contribute to potential cures. …”
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