Identification and Validation of a Novel Immune Infiltration-Based Diagnostic Score for Early Detection of Hepatocellular Carcinoma by Machine-Learning Strategies by Xuli Guo, Hailin Xiong, Shaoting Dong, Xiaobing Wei

“…To investigate the diagnostic gene biomarkers for hepatocellular carcinoma (HCC) and identify the immune cell infiltration characteristics in this pathology. …”
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The RNA M5C methyltransferase NSUN2 promotes progression of hepatocellular carcinoma by enhancing PKM2-mediated glycolysis by Qin Qi, Rui Zhong, Yan Huang, Yong Tang, Xiao-wen Zhang, Chang Liu, Chun-fang Gao, Lin Zhou, Jian Yu, Lu-yi Wu

“…Abstract Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. …”
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The Use of Machine Learning to Create a Risk Score to Predict Survival in Patients with Hepatocellular Carcinoma: A TCGA Cohort Analysis by Samer Tohme, Hamza O Yazdani, Amaan Rahman, Sanah Handu, Sidrah Khan, Tanner Wilson, David A Geller, Richard L Simmons, Michele Molinari, Christof Kaltenmeier

“…Introduction. Hepatocellular carcinoma (HCC) accounts for approximately 90% of primary liver malignancies and is currently the fourth most common cause of cancer-related death worldwide. …”
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TGF-β signaling orchestrates cancer-associated fibroblasts in the tumor microenvironment of human hepatocellular carcinoma: unveiling insights and clinical significance by Junwei Ge, Hongwei Jiang, Junjun Chen, Xuemin Chen, Yue Zhang, Liangrong Shi, Xiao Zheng, Jingting Jiang, Lujun Chen

Subjects: “…Hepatocellular carcinoma…”
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NOP2/Sun RNA Methyltransferase 4 Regulates the Mammalian Target of Rapamycin Signaling Pathway to Promote Hepatocellular Carcinoma Progression by Congren Wang, Shaoying Ke, Shaoze Lin, Conglin Lin, Zhibing Cai, Lingju Hong, Qunxiong Pan

“…Background/Aims: NOP2/Sun RNA methyltransferase 4 (NSUN4) is a prognostic indicator for hepatocellular carcinoma (HCC). However, the mechanism of NSUN4 in HCC is still unexplored. …”
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3D synergistic tumor-liver analysis further improves the efficacy prediction in hepatocellular carcinoma: a multi-center study by Yurong Jiang, Jiawei Zhang, Zhaochen Liu, Jinxiong Zhang, Xiangrong Yu, Danyan Lin, Dandan Dong, Mingyue Cai, Chongyang Duan, Shuyi Liu, Wenhui Wang, Yuan Chen, Qiyang Li, Weiguo Xu, Meiyan Huang, Sirui Fu

Subjects: “…Hepatocellular carcinoma…”
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Therapeutic Decision Making in Hepatocellular Carcinoma According to Age and Child–Pugh Class: A Nationwide Cohort Analysis in South Korea by Sunmin Park, Chai Hong Rim, Young Kul Jung, Won Sup Yoon

“…The Korean Liver Cancer Study Group randomly extracted the data of patients with hepatocellular carcinoma (HCC) enrolled in the Korean Central Cancer Registry from 2008 to 2014 from approximately 50 hospitals nationwide. …”
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Downregulation of hnRNPA1 inhibits hepatocellular carcinoma cell progression by modulating alternative splicing of ZNF207 exon 9 by Qi Ouyang, Qi Ouyang, Wenhui He, Yiping Guo, Lin Li, Ying Mao, Xiang Li, Shuanglin Xiang, Xiang Hu, Jun He

“…IntroductionHepatocellular carcinoma (HCC) is the most prevalent liver cancer and a leading cause of cancer-related deaths worldwide. …”
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Sorafenib enhanced the function of myeloid-derived suppressor cells in hepatocellular carcinoma by facilitating PPARα-mediated fatty acid oxidation by Chunxiao Li, Liting Xiong, Yuhan Yang, Ping Jiang, Junjie Wang, Mengyuan Li, Shuhua Wei, Suqing Tian, Yuexuan Wang, Mi Zhang, Jie Tang

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The Clinical Characteristics, Patterns of Recurrence, and Long-Term Survival Outcomes of Dual-Phenotype Hepatocellular Carcinoma After Curative Liver Resection by Yu ZC, Fang ZK, Yu Y, Liu SY, Wang KD, Shi ZJ, Jin LM, Huang XK, Lu Y, Shen GL, Liu JW, Huang DS, Zhang CW, Liang L

Subjects: “…hepatocellular carcinoma…”
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[18F]-(2S,4R)4-Fluoroglutamine PET Imaging of Glutamine Metabolism in Murine Models of Hepatocellular Carcinoma (HCC) by Youngho Seo, Miranda C. Craig, Stephanie T. Murphy, Jinjin Feng, Xin Chen, Mariia Yuneva

“…Quantitative in vivo [18F]-(2S,4R)4-fluoroglutamine ([18F]4-FGln or more simply [18F]FGln) metabolic kinetic parameters are compared with activity levels of glutamine metabolism in different types of hepatocellular carcinoma (HCC). Methods. For this study, we used two transgenic mouse models of HCC induced by protooncogenes, MYC, and MET. …”
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Habitat radiomics based on CT images to predict survival and immune status in hepatocellular carcinoma, a multi-cohort validation study by Kun Chen, Chunxiao Sui, Ziyang Wang, Zifan Liu, Lisha Qi, Xiaofeng Li

Subjects: “…Hepatocellular carcinoma…”
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The Combination of D-TACE-HAIC, Lenvatinib, and PD-1 Inhibitors Shows Significant Clinical Efficacy in Patients with Unresectable Hepatocellular Carcinoma by Wu Y, Zhu J, Zhang H, Xia N

Subjects: “…unresectable hepatocellular carcinomas…”
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High matrix stiffness accelerates migration of hepatocellular carcinoma cells through the integrin β1-Plectin-F-actin axis by Zhihui Wang, Wenbin Wang, Qing Luo, Guanbin Song

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Associations of miR-499 and miR-34b/c Polymorphisms with Susceptibility to Hepatocellular Carcinoma: An Evidence-Based Evaluation by Zhongxia Wang, Junhua Wu, Guang Zhang, Yin Cao, Chunping Jiang, Yitao Ding

“…Background. Hepatocellular carcinoma (HCC) represents the sixth common cancer in the world. …”
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AFP shields hepatocellular carcinoma from macrophage phagocytosis by regulating HuR-mediated CD47 translocation in cellular membrane by Yinglian Pan, Qiushi Yin, Zhaoliang Wang, Gang Wu, Kun Liu, Xiaowei Li, Jinchen Liu, Jiangzheng Zeng, Bo Lin, Wei Li, Mingyue Zhu, Mengsen Li

Subjects: “…Hepatocellular carcinoma…”
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High interstitial fluid pressure enhances USP1-dependent KIF11 protein stability to promote hepatocellular carcinoma progression by Zhengyi Wu, Chao Li, Shouhua Zhang, Liang Sun, Junwen Hu, Bingbing Qiu, Shuiqiu Liu, Yiran Hong, Tianxiang Chen, Kai Wang, Xiangbao Yin, Jinlong Yan

Subjects: “…Hepatocellular carcinoma…”
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Treatment of Advanced Hepatocellular Carcinoma after Failure of Sorafenib Treatment: Subsequent or Additional Treatment Interventions Contribute to Prolonged Survival Postprogression by Masaaki Kondo, Kazushi Numata, Koji Hara, Akito Nozaki, Hiroyuki Fukuda, Makoto Chuma, Shin Maeda, Katsuaki Tanaka

“…Sorafenib is a first-line treatment option for advanced hepatocellular carcinoma (HCC) patients; however, survival predictors upon progression have not been well characterized. …”
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A clinical study exploring the prediction of microvascular invasion in hepatocellular carcinoma through the use of combined enhanced CT and MRI radiomics. by Jiangfa Li, Wenxiang Song, Jixue Li, Lv Cai, Zhao Jiang, Mengxiao Wei, Boming Nong, Meiyu Lai, Yiyi Jiang, Erbo Zhao, Liping Lei

“…<h4>Objective</h4>To develop a predictive model for microvascular invasion (MVI) in hepatocellular carcinoma (HCC) through radiomics analysis, integrating data from both enhanced computed tomography (CT) and magnetic resonance imaging (MRI).…”
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FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A by Xing Wang, Ying Li, Yongning Li, Peng Liu, Songbai Liu, Yaozhen Pan

“…A previous study showed that the expression of FBXW7 in hepatocellular carcinoma (HCC) clinical samples was lower than that in the adjacent nontumor tissues and was negatively correlated with the invasion and migration of HCC cells. …”
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