Distribution of Hepatitis C Virus Genotypes in Canada: Results from the LCDC Sentinel Health Unit Surveillance System by RK Chaudhary, M Tepper, S Eisaadany, Paul R Gully

“…In a sentinel hepatitis surveillance study conducted by sentinel health units, 1469 patients were enrolled, and 959 (65.3%) were positive for antibody to hepatitis C virus (HCV). Samples from 387 patients (40.4%) were tested for HCV RNA, and 289 (74.7%) were positive for RNA. …”
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Direct-Acting Antivirals in Hepatitis C Treatment for Renal Impairment: Liver Safety Concerns and Effectiveness in Peritoneal Dialysis by Hsuan-Yu Hung, Wei-Liang Hung, Ye Gu, Chung-Yu Chen

“…<b>Background/Objectives:</b> Glecaprevir/pibrentasvir (G/P) and elbasvir/grazoprevir (EBR/GZR) are effective treatments for chronic hepatitis C (CHC), especially in patients with chronic kidney disease (CKD). …”
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Synthesis of some benzimidazole derivatives endowed with 1,2,3-triazole as potential inhibitors of hepatitis C virus by Youssif Bahaa G. M., Mohamed Yaseen A. M., Salim Mohammed T. A., Inagaki Fuyuhiko, Mukai Chisato, Abdu-Allah Hajjaj H. M.

“…New derivatives of 2-thiobenzimidazole incorporating triazole moiety were synthesized, characterized and tested in vitro for antiviral activity against hepatitis C virus (HCV) and hepatitis B virus (HBV). …”
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A New Metabolism-Related Index Correlates with the Degree of Liver Fibrosis in Hepatitis C Virus-Positive Patients by Hirayuki Enomoto, Nobuhiro Aizawa, Hideji Nakamura, Ryo Takata, Yoshiyuki Sakai, Yoshinori Iwata, Hironori Tanaka, Naoto Ikeda, Tomoko Aoki, Kunihiro Hasegawa, Kazunori Yoh, Kenji Hashimoto, Akio Ishii, Tomoyuki Takashima, Masaki Saito, Hiroyasu Imanishi, Hiroko Iijima, Shuhei Nishiguchi

“…The aim of this study was to investigate the relevance of an index obtained from three metabolic variables (glycated albumin: GA, glycated hemoglobin: HbA1c, and branched-chain amino acids to tyrosine ratio: BTR) to the degree of liver fibrosis in hepatitis C virus virus- (HCV-) positive patients. Methods. …”
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Long-term outcome in people who use drugs successfully treated for hepatitis C infection with glecaprevir/pibrentasvir by Shana Yi, David Truong, Brian Conway

“…Background: Several clinical trials, including the recently published the GRAND PLAN study from Vancouver Infectious Diseases Center (VIDC), have demonstrated the efficacy of hepatitis C (HCV) therapy among active drug users, including those facing significant addiction-related and social challenges. …”
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Barriers to and impacts of hepatitis C treatment among people who inject drugs in Kenya: A qualitative study. by Hannah N Manley, Lindsey R Riback, Mercy Nyakowa, Matthew J Akiyama, Peter Cherutich, John Lizcano, Ann Kurth, Abbe Muller

“…Hepatitis C (HCV) disproportionately affects people who inject drugs (PWID). …”
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Seroprevalence of Hepatitis C, Hepatitis B, Cytomegalovirus, and Human Immunodeficiency Viruses in Multitransfused Thalassemic Children in Upper Egypt by Ramadan A. Mahmoud, Abdel-Azeem M. El-Mazary, Ashraf Khodeary

“…The aim of this study was to estimate the prevalence of hepatitis C virus (HCV), hepatitis B virus (HBV), human immunodeficiency virus (HIV), and cytomegalovirus (CMV) in thalassemic children attending the Pediatrics Departments of both Sohag and Minia Universities of Upper Egypt, during the period from May 2014 to May 2015. …”
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Prevalence and clinical profile of hepatitis C virus infections in multitransfused thalassemic patients in the capital twin cities of Pakistan by Z. Z. Piracha, U. Saeed, R. Uppal, M. R. Uppal, A. Ahmad Khan, M. Abdullah, K. Mari, A. Basra, S. S. Gilani, M. N. Tariq, D. U. Ozsahin, B. Uzun, I. Ozsahin

Subjects: “…hepatitis C virus…”
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Barriers to and impacts of hepatitis C treatment among people who inject drugs in Kenya: A qualitative study by Hannah N. Manley, Lindsey R. Riback, Mercy Nyakowa, Matthew J. Akiyama, Peter Cherutich, John Lizcano, Ann Kurth, Abbe Muller

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Randomized controlled effect of treadmill walking exercise on liver enzymes, psychological burden, and erectile dysfunction in men with hepatitis C by Ali Ismail, Nadia Saad Sayed Ahmed El Gressy, Mona Darwish Hegazy, Ahmed Mohamed Abdel-Halim Elfahl, Omnia Saeed Mahmoud Ahmed

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Real-life study on the effectiveness and safety of sofosbuvir/velpatasvir-based antiviral agents for hepatitis C eradication in Chinese patients by Jiayi Wang, Lingyao Du, Dongmei Zhang, Chen Zhou, Yilan Zeng, Miao Liu, Xing Cheng, Xiaona Song, Han Chen, Ning Han, Enqiang Chen, Hong Tang

Subjects: “…Hepatitis C…”
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The clinical role of blood coagulation and platelet receptors gene allelic variants in development of cryoglobulinemic vasculitis at chronic hepatitis C by Yekaterina Ye. Starostina, M. V. Sokolova, L. M. Samokhodskaya, T. П. Rozina, T. N. Krasnova, Ye. B. Yarovaya, N. A. Mukhin

“…To estimate the clinical and prognostic value of carriage of various blood coagulation and platelet receptors gene allelic variants in development of cryoglobulinemic vasculitis at chronic hepatitis C (CHC). Material and methods. Original study included overall 200 patients with CHCs and liver cirrhosis in its outcome, who were divided into 3 groups: patients without cryoglobulinemia (CG, n=123), those with asymptomatic cryoglobulinemia (ACG, n=40) and with cryoglobulinemic vasculitis (CGV, n=37). …”
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Frequency of Fibromyalgia in Patients with Chronic Hepatitis C Virus Infection and Its Relationship with Vitamin D Levels and Quality of Life by Havva Talay Calis, Fatma Gul Ulku Demir, Ulas Serkan Topaloglu, Hatice Sayan, Deniz Kamalak Guzel, Emel Guler, Fatma Samli, Caglar Karabas, Serap Tomruk Sutbeyaz, Hatice Kayis Topaloglu

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Determinants of Antiviral Treatment Initiation in a Hepatitis C-infected Population Benefiting from Universal Health Care Coverage by Romain Moirand, Marc Bilodeau, Suzanne Brissette, Julie Bruneau

“…BACKGROUND AND AIMS: In view of increasing therapeutic efficacy, the delivery of hepatitis C virus (HCV) antiviral treatment is expected to increase. …”
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Resistance-Associated Substitutions (RAS) and Clinical Factors as Determinants of Sofosbuvir-Daclatasvir Treatment Outcomes in Chronic Hepatitis C Patients by Juferdy Kurniawan, Anugrah Dwi Handayu, Gita Aprilicia, Darlene Raudhatul Bahri, Irsan Hasan

Subjects: “…hepatitis c…”
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The Burden of Hepatitis C Virus Infection Is Growing: A Canadian Population-Based Study of Hospitalizations from 1994 to 2004 by Robert P Myers, MingFu Liu, Abdel Aziz M Shaheen

“…BACKGROUND: Nearly 1% of Canadians are infected with the hepatitis C virus (HCV). Simulation analyses have suggested that HCV will place an increasing burden on the health care system as the infected population ages, but supportive clinical data are limited.…”
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Five-Year Prospective Follow-Up of Patients with Hepatitis C Virus Infection Treated with Direct-Acting Antiviral Agents by Zhang Y, Xia H, Fan L, Jiang L, Yang B, Wang F

Subjects: “…chronic hepatitis c…”
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Genetic Variation in the IL-6 and HLA-DQB1 Genes Is Associated with Spontaneous Clearance of Hepatitis C Virus Infection by Paul Ravi Waldron, Ilana Belitskaya-Lévy, Aarthi Chary, Johann Won, Mark Winters, Alexander Monto, James Ryan, Laura C. Lazzeroni, Mark Holodniy

“…Millions of people are infected with hepatitis C virus (HCV) worldwide and 30% spontaneously clear the infection. …”
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Are We Aware of Hepatitis C Infection? HCV Results from the Tertiary Reference Center in the Aegean Region from Turkey by Gözde Derviş Hakim, Pınar Şamlıoglu, Murat Aysin, Taner Kara, Şükran Köse

“…With the advent of direct-acting antiviral agents, the rate of sustained virological response in the treatment of hepatitis C virus (HCV) infection has reached 100%. …”
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Transitioning to Highly Effective Therapies for the Treatment of Chronic Hepatitis C Virus Infection: A Policy Statement and Implementation Guideline by Daniel J Smyth, Duncan Webster, Lisa Barrett, Mark MacMillan, Lisa McKnight, Frank Schweiger

“…Chronic hepatitis C virus (HCV) infection increases all-cause mortality, rates of cirrhosis, hepatocellular carcinoma, liver transplantation and overall health care utilization. …”
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