Livogrit mitigates ANIT-induced cholestasis-like symptoms in an in vivo model by curbing hepatic inflammation and regulating BAX, TGF-β, MMP-9 and α-SMA gene expression by Acharya Balkrishna, Ritu Paliwal, Surjeet Singh, Rani Singh, Vivek Gohel, Rishabh Dev, Kunal Bhattacharya, Sandeep Sinha, Anurag Varshney

“…Bile duct constriction disrupts bile acid flow causing cholestasis, hepatic necrosis, fibrosis, and cirrhosis. The study investigated hepatoprotective effectiveness of Ayurvedic prescription herbal medicine “Livogrit” commercially available in India, against α-naphtylisothiocyanate (ANIT)-induced cholestasis-like symptoms in male Sprague-Dawley rats. …”
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Modelling the potential clinical and economic impact of universal antenatal hepatitis C (HCV) screening and providing treatment for pregnant women with HCV and their infants in Egypt: a cost-effectiveness study by Giuseppe Indolfi, Diana M Gibb, Aya Mostafa, Sarah Pett, Yazdan Yazdanpanah, Sylvie Deuffic-Burban, Anthony E Ades, Karen Scott, Ali Judd, Nadia Hachicha-Maalej, Clotilde Lepers, Intira Jeannie Collins, Manal H El Sayed

“…Backgrounds and aims Pregnant women and children are not included in Egypt’s hepatitis C virus (HCV) elimination programmes. This study assesses the cost-effectiveness of several screening and treatment strategies for pregnant women and infants in Egypt.Design A Markov model was developed to simulate the cascade of care and HCV disease progression among pregnant women and their infants according to different screening and treatment strategies, which included: targeted versus universal antenatal screening; treatment of women in pregnancy or deferred till after breast feeding; treatment of infected children at 3 years vs 12 years. …”
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Liver Imaging and Data System (LI-RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral Infection by Ying-ying Liang, Shuo Shao, Sichi Kuang, Jingbiao Chen, Jing Zhou, Bingjun He, Linqi Zhang, Yao Zhang, Kathryn J. Fowler, Jin Wang

“…To describe liver imaging reporting and data system (LI-RADS) version 2018 and other MRI imaging features in intrahepatic mass-forming cholangiocarcinoma (iCCA) in Chinese adults with vs. without chronic hepatitis B viral (HBV) infection. Methods. We retrospectively enrolled 89 patients with pathologically proven iCCA after multiphase imaging performed between 2004 and 2017 at a tertiary medical center in southern China. …”
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The Effects of Extra Virgin Olive Oil on Alanine Aminotransferase, Aspartate Aminotransferase, and Ultrasonographic Indices of Hepatic Steatosis in Nonalcoholic Fatty Liver Disease Patients Undergoing Low Calorie Diet by Farzad Shidfar, Samaneh Sadat Bahrololumi, Saeid Doaei, Assieh Mohammadzadeh, Maryam Gholamalizadeh, Ali Mohammadimanesh

“…The consumption of a low calorie diet enriched with olive oil, along with slight weight reduction, reinforces the desired effects of weight loss in improving the levels of the hepatic enzymes.…”
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Can Early Diagnosis of Varices, Regular Praziquantel, and Reduction of Hepatitis Coinfection Reduce Mortality among Patients Attended for Periportal Fibrosis in Northwestern Tanzania?... by Daniel W. Gunda, Elizabeth F. Mtui, Semvua B. Kilonzo, Paulina M. Manyiri, David C. Majinge, Humphrey D. Mazigo

“…In this, S. mansoni endemic area, varices, actives schistosomiasis, hepatitis B coinfection, and mortality are highly common. …”
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Thirteen-Year Follow-Up of a Patient with Liver Cirrhosis Resulting from the Overlap Syndrome of Autoimmune Hepatitis and Primary Biliary Cholangitis: Severe COVID-19 and Liver Transplantation by A. Kh. Odintsova, D. R. Akberova, L. R. Sadykova, N. A. Cheremina, M. M. Minnullin, A. A. Kirshin, E. N. Gabitova, A. Yu. Khasanshina, D. I. Abdulganieva

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Polyphenols and pectin enriched golden kiwifruit (Actinidia chinensis) alleviates high fructose-induced glucolipid disorders and hepatic oxidative damage in rats: in association with improvement of fatty acids metabolism by Aamina Alim, Ting Li, Tanzeela Nisar, Zeshan Ali, Daoyuan Ren, Yueyue Liu, Xingbin Yang

“…Especially, ACFP considerably ameliorated HF-induced abnormal changes in body weight gain, serum TC, TG, LDL-C and HDL-C levels, as well as serum and hepatic SFAs, MUFAs and PUFAs contents. ACFP also alleviated HF-induced hyperglycemia and hyperinsulinemia, stabilized HF-caused increase in hepatic MDA and serum ALT, AST levels, and restored HF-declined hepatic T-SOD and GSH-Px activities. …”
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AdipoRon mitigates liver fibrosis by suppressing serine/glycine biosynthesis through ATF4-dependent glutaminolysis by Xiangting Zhang, Yuan Zeng, Huiya Ying, Yiwen Hong, Jun Xu, Rong Lin, Yuhao Chen, Xiao Wu, Weimin Cai, Ziqiang Xia, Qian Zhao, Yixiao Wang, Ruoru Zhou, Dandan Zhu, Fujun Yu

Subjects: “…Hepatic stellate cells…”
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Dietary Interventions and Physical Activity as Crucial Factors in the Prevention and Treatment of Metabolic Dysfunction-Associated Steatotic Liver Disease by Paweł Rajewski, Jakub Cieściński, Piotr Rajewski, Szymon Suwała, Alicja Rajewska, Maciej Potasz

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Modern Possibilities of Using Lactulose in Clinical Practice by A. A. Sheptulin

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Transcriptional analysis of murine biliary atresia identifies macrophage heterogeneity and subset-specific macrophage functions by Kyle D. Gromer, Shang-Yang Chen, Gaurav Gadhvi, Liang Feng, Colin Shearn, Swati Antala, Swati Antala, Joshua B. Wechsler, Carla M. Cuda, Cara L. Mack, Ronald J. Sokol, William J. Janssen, Richard M. Green, Harris Perlman, Deborah R. Winter, Sarah A. Taylor, Sarah A. Taylor

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Does repeat laparoscopic hepatectomy without extracorporeal Pringle manoeuvre worsen treatment outcomes? by Yoshihiro Inoue, Yusuke Suzuki, Masato Ota, Kazuya Kitada, Toru Kuramoto, Kentaro Matsuo, Kensuke Fujii, Yuta Miyaoka, Fumiharu Kimura, Kazuhisa Uchiyama

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Alteration of fecal microbiome and metabolome by mung bean coat improves diet-induced non-alcoholic fatty liver disease in mice by Dianzhi Hou, Jian Tang, Meili Huan, Fang Liu, Sumei Zhou, Qun Shen

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Longitudinal serological and virological survey of hepatitis E virus in wild boar (Sus scrofa majori, Maremman wild boar) and fallow deer (Dama dama) populations in a protected area of Central Italy by Luca De Sabato, Mariagiovanna Domanico, Paola De Santis, Daniele Cecca, Giulia Bonella, Giovanni Mastrandrea, Roberta Onorati, Luigi Sorbara, Bianca Maria Varcasia, Barbara Franzetti, Andrea Caprioli, Antonio Battisti, Fabio Ostanello, Ilaria Di Bartolo

Subjects: “…hepatitis E…”
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Long-Term Analysis of Recurrence Beyond Milan Criteria Following Ablation of Solitary Early-Stage Hepatocellular Carcinoma ≤3 cm in Potentially Transplantable Patients: A Over 1... by Chen S, Qi H, Tan H, Cao F, Xie L, Huang T, Wu Y, Wen C, Wang Y, Shen L, Fan W

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Optimal control problems with time delays: Two case studies in biomedicine by Laurenz Göllmann, Helmut Maurer

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Immunogenicity persistence after four intramuscular triple-dose or standard-dose hepatitis B vaccine in patients receiving methadone maintenance treatment: A 1-year follow-up study in China by Xinyuan Mo, Zhaoyue Men, Linying Gao, Yizhuo Gao, Tian Yao, Yuan Liu, Yuan Yuan, Tongchuan Xue, Fuzhen Wang, Suping Wang, Keke Wang, Xiaofeng Liang, Yongliang Feng

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Forkhead Box Protein-3 Gene Expression of Purified Human Peripheral Blood Mononuclear Cells Treated with Methicillin-Resistant Staphylococcus aureus-Somatic Antigens and Hepatitis B Virus Vaccine by Entidhar A. Hadi, Mohammad A. K. Al-Saadi, Kaiser N. Madlum

“…Background: Optimal hepatitis B virus (HBV) vaccine efficacy linked to producing systemic and mucosal antibodies and cellular immunological memory requires a complete set of immunological responses. …”
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miRNA-221: A Potential Biomarker of Progressive Liver Injury in Chronic Liver Disease (CLD) due to Hepatitis B Virus (HBV) and Nonalcoholic Fatty Liver Disease (NAFLD) by Parthana Rani Sutradhar, Nahida Sultana, Afzalun Nessa

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Hepatitis B Vaccination Induced TNF-α- and IL-2-Producing T Cell Responses in HIV− Healthy Individuals Higher than in HIV+ Individuals Who Received the Same Vaccination Regimen by Kriangkrai Chawansuntati, Kanokporn Chaiklang, Romanee Chaiwarith, Jutarat Praparattanapan, Khuanchai Supparatpinyo, Jiraprapa Wipasa

“…PBMCs collected at different time points were stimulated in vitro with recombinant hepatitis B surface antigen and analyzed by flow cytometry. …”
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