Navigating the complex role of senescence in liver disease by Qiuting Li, Lin Wang, Yuanyuan Ji

“…The therapeutic potential of these interventions, alongside their safety and effectiveness, highlights the need for further research to refine these approaches and address unresolved problems in the field of hepatic cellular senescence.…”
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Histopathological Study of Bee Venom with Different Concentrations in Laboratory Mice by Zeyad G. Al-Rikabi, Montaha Abdulkareem Al-Saffar, Huda S. Nassir, Inam B. Falih

“…Whereas several mild degenerative changes were observed in hepatic cells of one group. In conclusion, bee venom administered to groups in different concentrations revealed hepatic and renal complications at histological investigations of hematoxylin and eosin-stained sections of liver and kidney section. …”
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Protective Effects of Celastrol on Diabetic Liver Injury via TLR4/MyD88/NF-κB Signaling Pathway in Type 2 Diabetic Rats by Li-ping Han, Chun-jun Li, Bei Sun, Yun Xie, Yue Guan, Ze-jun Ma, Li-ming Chen

“…Celastrol-treated diabetic rats show reduced hepatic inflammation and macrophages infiltration. …”
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Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest Yemen by Mohamed Al-Salahy, Bushra Shnawa, Gamal Abed, Ahmed Mandour, Ali Al-Ezzi

“…The present study aims to investigate changes in hematological and hepatic function indices of P. falciparum infected individuals. …”
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DUOX2 Expression Is Increased in Barrett Esophagus and Cancerous Tissues of Stomach and Colon by Ran Qi, Yunfeng Zhou, Xiaozhen Li, Hong Guo, Lei Gao, Lijuan Wu, Yufeng Wang, Qiang Gao

“…In CRC tissues, the DUOX2 protein expression level in stages II–IV was significantly higher than that in stage I. In both hepatic carcinoma and the adjacent nonmalignant tissue, the DUOX2 was virtually undetectable. …”
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Detectability of Liver Steatosis and Fibrosis with Transient Elastography and Controlled Attenuation Parameter in Residents of St. Petersburg by V. P. Kovyazina, K. L. Raikhelson, M. K. Prashnova, E. V. Pazenko, L. K. Palgova, E. A. Kondrashina

“…Transient elastography with the controlled attenuation parameter estimation provides a convenient non-invasive screening for hepatic fibrosis and steatosis.…”
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Physiological accumulation of lipid droplets in the newborn liver during breastfeeding is driven by TLR4 ligands by Wanderson Ferreira da Silva Júnior, Karen Marques de Oliveira Costa, Hortência Maciel Castro Oliveira, Maísa Mota Antunes, Kassiana Mafra, Brenda Naemi Nakagaki, Pedro Sérgio Corradi da Silva, Júlia Duarte Megale, Sarah Campos de Sales, Douglas Carvalho Caixeta, Mário Machado Martins, Robinson Sabino-Silva, Cristina Maria Pinto de Paula, Luiz Ricardo Goulart, Rafael Machado Rezende, Gustavo Batista Menezes

“…Here we investigated a transient surge in hepatic lipid droplets observed in newborn mice immediately after birth. …”
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AlphaFold-based AI docking reveals AMPK/SIRT1-TFEB pathway modulation by traditional Chinese medicine in metabolic-associated fatty liver disease by Lulu Zhang, Yi Zheng, Mingyan Shao, Aiping Chen, Meiyi Liu, Wenlong Sun, Tianxing Li, Yini Fang, Yang Dong, Shipeng Zhao, Hui Luo, Juan Feng, Qi Wang, Lingru Li, Yanfei Zheng

“…Metabolic-associated fatty liver disease (MAFLD) is a chronic, progressive disorder characterized by hepatic steatosis and excessive lipid accumulation. …”
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Anterograde Colonic Stent Placement via a Cecostomy Tube Site by Lawrence M Gillman, Steven Latosinsky

“…A unique case is presented where the colonic stent was passed in an anterograde fashion through a recently created cecostomy tube site as a method of palliation to relieve an obstructing hepatic flexure tumour.…”
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An Egyptian child with Wolman disease presenting with hemophagocytic lymphohistiocytosis by Rabab El Hawary, Safa Meshaal, Alia S. Eldash, Sohilla Lotfy, Dalia Abd Elaziz, Radwa Alkady, Rania Darwish, Aya Erfan, Mai Saad, Engy Chohayeb, Nermeen Galal, Aisha M. Elmarsafy

“…CESD has lower mortality and presents by hyperlipidemia, atherosclerosis, and hepatic fibrosis, while WD classic presentations include hepatosplenomegaly, malabsorption, failure to thrive, and organ-specific symptoms such as hepatic damage or adrenal calcification. …”
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The Pull-Through Technique for Recanalization of Transjugular Intrahepatic Portosystemic Shunt Dysfunction by Si-liang Chen, Cheng-jiang Xiao, Shuai Wang, Si-yi Jin, Jian-bo Zhao

“…During the follow-up, three patients developed hepatic encephalopathy, and one patient developed TIPS dysfunction again and experienced variceal bleeding. …”
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Nuclear Imaging to Detect Diaphragmatic Perforation as a Rare Complication of Microwave Ablation by Stephanie Cull, Gebran Khneizer, Abhishek Krishna, Razi Muzaffar, Sameer Gadani, Zafar Jamkhana

“…Acquired diaphragmatic perforation leading to massive hepatic hydrothorax and respiratory failure is a rare complication of microwave ablation (MWA) of hepatocellular carcinoma (HCC). …”
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Western diet promotes the progression of metabolic dysfunction‐associated steatotic liver disease in association with ferroptosis in male mice by Nicole Maddie, Nefia Chacko, David Matatov, Maria Alicia Carrillo‐Sepulveda

“…Histopathological analysis demonstrated the progression of MASLD to MASH in the obese group, which was accompanied by significant hepatic iron deposition, oxidative damage, and lipid peroxidation. …”
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Chronic Ethanol Feeding Modulates Inflammatory Mediators, Activation of Nuclear Factor-κB, and Responsiveness to Endotoxin in Murine Kupffer Cells and Circulating Leukocytes by Miriam Maraslioglu, Elsie Oppermann, Carolin Blattner, Roxane Weber, Dirk Henrich, Christian Jobin, Elke Schleucher, Ingo Marzi, Mark Lehnert

“…We found that chronic ethanol upregulated NF-κB activation and increased hepatic and systemic proinflammatory cytokine levels. …”
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Circulatory Support with Venoarterial ECMO Unsuccessful in Aiding Endogenous Diltiazem Clearance after Overdose by Erin N. Frazee, Sarah J. Lee, Ejaaz A. Kalimullah, Heather A. Personett, Darlene R. Nelson

“…In cardiovascular collapse from diltiazem poisoning, extracorporeal membrane oxygenation (ECMO) may offer circulatory support sufficient to preserve endogenous hepatic drug clearance. Little is known about patient outcomes and diltiazem toxicokinetics in this setting. …”
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The Pathogenesis of Nonalcoholic Fatty Liver Disease: Interplay between Diet, Gut Microbiota, and Genetic Background by Jinsheng Yu, Sharon Marsh, Junbo Hu, Wenke Feng, Chaodong Wu

“…Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the world, and it comprises a spectrum of hepatic abnormalities from simple hepatic steatosis to steatohepatitis, fibrosis, cirrhosis, and liver cancer. …”
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Anti-Glycemic and Anti-Hepatotoxic Effects of Mangosteen Vinegar Rind from Garcinia mangostana Against HFD/STZ-Induced Type II Diabetes in Mice by Karim Naymul, Jeenduang Nutjaree, Tangpong Jitbanjong

“…MVR and glibenclamide treatment to HFD/STZ-induced diabetic mice significantly reduced their plasma glucose, plasma lipid profile, and hepatic lipid profile (P<0.05). Increased hepatic glycogen content indicates improvement of insulin sensitivity. …”
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Relevance of the GH-VEGFB/VEGFA axis in liver grafts from brain-dead donors with alcohol-associated liver disease by Marc Micó-Carnero, Marc Micó-Carnero, Carlos Rojano-Alfonso, Carlos Rojano-Alfonso, Cristina Maroto-Serrat, Cristina Maroto-Serrat, Juan Carlos Cutrin, Araní Casillas-Ramírez, Araní Casillas-Ramírez, Carmen Peralta

“…Survival was monitored using an in vivo transplantation model.ResultsIn DBDs, the administration of GH, which increased the levels in the intestine but not in the liver, induced the generation of both VEGFA and VEGFB in the intestine and protected against hepatic damage caused by BD before retrieving liver grafts from donors. …”
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Reversal of acetaminophen-generated oxidative stress and concomitant hepatotoxicity by a phytopharmaceutical product by Afolabi C. Akinmoladun, Kehinde O. Oguntunde, Lawrence O. Owolabi, Omotayo B. Ilesanmi, Joan O. Ogundele, M.Tolulope Olaleye, Afolabi A. Akindahunsi

“…In this study, Trévo™, a nutraceutical and phytopharmaceutical product, was evaluated for beneficial effects in acetaminophen-induced hepatic toxicity in Wistar rats. Animals received Trévo™ (1.5 mL/kg, 3.0 mL/kg or 4.5 mL/kg) orally for 14 days. …”
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Effects of Aminoglycoside Antibiotics on Human Embryonic Stem Cell Viability during Differentiation In Vitro by Divya S. Varghese, Shama Parween, Mustafa T. Ardah, Bright Starling Emerald, Suraiya A. Ansari

“…However, during directed differentiation towards neural and hepatic fate, significant cell death was noted through the activation of caspase cascade. …”
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