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2521
Exploring the efficacy of fluorouracil and platinum based chemotherapy in advanced hepatocellular carcinoma to bridge the treatment gap in resource limited settings
Published 2025-01-01“…A high pretreatment neutrophil-to-lymphocyte ratio (≥ 3.0) adversely affected both PFS (HR = 1.79; 95% CI, 0.99–3.25; p = 0.034) and OS (HR = 2.02; 95% CI, 1.10–3.69; p = 0.011). Hematologic toxicities related to the treatment were substantial, with 62.5% of patients experiencing grade 3 or 4 events, primarily neutropenia, which affected 60.4% of them. …”
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2522
The Impact of COVID-19 on Clinical Outcomes in Patients With Traumatic Brain Injury
Published 2025-01-01“…COVID-19 can impact the central nervous system (CNS) and hematologic system and appears to affect clinical outcomes and the average cerebral hemorrhage volume (ACHV) in patients with TBI. …”
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2523
Methanolic Extract of Distemonanthus benthamianus (Caesalpiniaceae) Stem Bark Suppresses Ethanol/Indomethacin-Induced Chronic Gastric Injury in Rats
Published 2020-01-01“…In addition, the extract significantly decreases the level of MDA, significantly increases the activities of catalase and glutathione, and then improves the hematological parameters in sick animals. Histological micrographs show that in the presence of the extract, there is advanced reepithelialization with recovery of the ulcerated epithelium. …”
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2524
Dysregulated T Cell Activation and Aberrant Cytokine Expression Profile in Systemic Lupus Erythematosus
Published 2019-01-01“…In addition, patients with hematologic manifestations displayed elevated frequencies of HLA-DR+ T cells and ICOS+ T cells. …”
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2525
Clerodendrum volubile Ethanol Leaf Extract: A Potential Antidote to Doxorubicin-Induced Cardiotoxicity in Rats
Published 2020-01-01“…Doxorubicin is widely applied in hematological and solid tumor treatment but limited by its off-target cardiotoxicity. …”
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2526
The effects of fluid resuscitation on the hemodynamic parameters of experimental induced endotoxemia in the neonatal calves
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2527
Safety and effectiveness of an herbal decoction (modified Saengmaeksan) in hypertensive patients: Protocol for a real-world prospective observational study.
Published 2025-01-01“…Safety assessments will include monitoring hematologic parameters and adverse events. Data will be analyzed using an ANCOVA model for adjusting confounders.…”
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2528
Effects of High Dietary Inclusion of Defatted Mealworm (Tenebrio molitor) Meal as a Fish Meal Substitute on Growth, Histological Traits, and Health Performances of Rainbow Trout (O...
Published 2025-01-01“…Substitution of FM with DMW did not significantly affect hematological electrolyte, acid–base, and blood gas parameters, except for sodium (Na) concentration. …”
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2529
Shift in the profile and prognostic implications in invasive fungal rhinosinusitis: experience of 10 years in a tertiary center
Published 2025-02-01“…The most frequents underlying conditions were hematological malignancies (76.5%) and solid organ transplantation (11.8%). …”
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2530
Measurement the Physiological Properties of Water Pipe Smokers in Shekhan Distract
Published 2019-08-01“…Sample had been taken through blood collection from 100 who are water pipe smoker and 100 who not smoke, and this include the following physiological test: Heart Rate, Blood Pressure, and Respiratory Flow Rate, in addition with laboratory hematological test Hemoglobin. The results showed an increase in the rate of (Blood pressure, Inspiratory Flow Rate, Heart rate, Hemoglobin) and rates higher after smoking as follow for Blood Pressure after smoking systolic was141.9±6.021 and diastolic 91.75 ±4.459 While the inspiratory flow rate reading after smoking 963.5 ±96.624, the heart rate reading after smoking was 83.27 ±7.84 while the hemoglobin the reading was 15.68 ±0.87 as recorded after finishing smoking . …”
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2531
Assessment of Haematological Parameters in Drug-Resistant TB
Published 2023-03-01“…The goals of this study are (a) to assess the hematological characteristics of TB patients, and (b) to examine the impact of rifampin (RIF) resistance on the prevalence of mutations in the whole rpoB gene of Mycobacterium tuberculosis. …”
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2532
Prognostic factors and survival outcomes in patients with salivary duct carcinoma: a retrospective cohort study
Published 2025-01-01“…These findings underscore the potential significance of incorporating hematological parameters and metastatic status into clinical decision-making to optimize risk stratification and personalized treatment strategies.…”
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2533
CC-96673 (BMS-986358), an affinity-tuned anti-CD47 and CD20 bispecific antibody with fully functional fc, selectively targets and depletes non-Hodgkin’s lymphoma
Published 2024-12-01“…To date, the advancement of CD47-targeted modalities is hindered by the ubiquitous expression of the target, often leading to rapid drug elimination and hematologic toxicity including anemia. To overcome those challenges a bispecific approach was taken. …”
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2534
Tissue-specific roles of de novo DNA methyltransferases
Published 2025-01-01“…Additionally, somatic mutations cause common conditions such as osteoarthritis, osteoporosis, clonal hematopoiesis of indeterminate potential (CHIP), hematologic malignancies, and cancer. While DNMTs have been extensively studied in vitro, in early development and in disease, their detailed physiologic roles remain less understood as in vivo investigations are hindered by the embryonic or perinatal lethality of the knockout mice. …”
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2535
Korelasi nilai mean platelet volume dengan derajat fibrosis hati pada pasien hepatitis B kronik
Published 2020-04-01“…Pemeriksaan nilai MPV menggunakan alat analisis hematologi otomatis metode impedensi. Data dianalisis dengan uji korelasi Pearson. …”
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2536
Elevation of Circulating miR-210 Participates in the Occurrence and Development of Type 2 Diabetes Mellitus and Its Complications
Published 2022-01-01“…Totally, 137 serum samples from patients with T2DM were collected; meanwhile, the demographic, general, and clinical hematological characteristics, disease history, and dietary patterns were recorded. …”
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2537
Contributing factors to postoperative surgical site infections in pituitary neuroendocrine tumors undergoing endonasal transsphenoidal resection
Published 2025-01-01“…Diagnostic criteria for intracranial infections were based on clinical, hematological, cerebrospinal fluid, radiological, and microbiological findings. …”
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2538
Antioxidant Potential, Subacute Toxicity, and Beneficiary Effects of Methanolic Extract of Pomelo (Citrus grandis L. Osbeck) in Long Evan Rats
Published 2019-01-01“…In addition, no significant alterations in the hematological parameters were also observed. However, rats which received 1000 mg/kg dose had a significant reduction in some serum parameters, including alanine transaminase (15.29%), alkaline phosphatase (2.5%), lactate dehydrogenase (15.5%), γ-glutamyltransferase (20%), creatinine (14.47%), urea (18.50%), uric acid (27.14%), total cholesterol (5.78%), triglyceride (21.44%), low-density lipoprotein cholesterol (40.74%), glucose (2.48%), and all atherogenic indices including cardiac risk ratio (24.30%), Castelli’s risk index-2 (45.71%), atherogenic coefficient (42%), and atherogenic index of plasma (25%) compared to control. …”
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2539
Risk of recurrence and bleeding in patients with cancer‐associated venous thromboembolism treated with rivaroxaban: A nationwide cohort study
Published 2019-03-01“…Most frequent cancers were gastrointestinal (26.1%), genitourinary (23.3%), and hematological cancer (12.6%). Few had distant metastases (7.1%). …”
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2540
Early Radiologic Diagnosis of Pulmonary Infection in Febrile Neutropenic Patients: A Comparison of Serial Chest Radiography and Single CT Chest
Published 2021-01-01“…This study included 78 patients with hematologic malignancies who developed 107 episodes of febrile neutropenia from January 2012 to October 2017 and had a chest film performed within the first seven days. …”
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