Deferasirox improved iron homeostasis and hematopoiesis in ovariectomized rats with iron accumulation by Niloofar Honari, Mahtab Sayadi, Seyed Mehdi Sajjadi, Somayeh Solhjoo, Gholamreza Anani Sarab

“…Deferasirox was administered at doses of 50 mg/kg and 100 mg/kg. Hematological parameters, iron profile, antioxidant markers, oxidative stress indicators, histopathological evaluation of uterine, bone, bone marrow, liver, and spleen tissues, flow cytometric analysis of hematopoietic CD markers, and relative expression of Hamp, Pu.1, Gata1, and Gdf11 genes were analyzed. …”
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Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency by V. S. Scherbakha, O. Z. Okhlobystina, A. V. Korolev, O. S. Shifrin, A. V. Stepanov, A. S. Tertychny, A. V. Okhlobystin, V. T. Ivashkin

“…Later on patient underwent examination to exclude hematological disorder. In 1.5 years before admission to Vasilenko clinic of Sechenov University patient lost 30 kg of body weight. …”
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Risk versus Benefit of Using Hydroxychloroquine to Treat Patients with COVID-19 by George G. Zhanel, Michael A. Zhanel, Kevin F. Boreskie, Joseph P. Lynch, James A. Karlowsky

“…Additionally, these same trials reported adverse events including cardiac, neuropsychiatric, hematologic, and hepatobiliary manifestations in patients with COVID-19 whom had been treated with HCQ. …”
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Improvement of Quality of Life after Surgical Treatment of Patients with MRONJ: A Prospective Analysis Using the SF-12 and OHIP-14 Questionnaires by Georg Hoene, Nikolaus von Hahn, Denise Sievers, Lukas Schuffelen, Susanne Wolfer, Kathi Goldstein, Boris Schminke, Phillipp Brockmeyer, Philipp Kauffmann

“…Medication-related osteonecrosis of the jaw (MRONJ) is a rare, serious, and debilitating disease of unknown cause that can be associated with significant health-related quality of life (HRQOL) impairment. Hematological disease is characterized by a nonhealing exposed jawbone in patients with a history of antiresorptive or antiangiogenic agent use without radiation exposure to the head or neck. …”
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Protective effects of myrtenol against paraquat-induced toxicity in rats by Fatemeh Amin, Hosein Basirat, Najmeh Parvaz, Morteza Khademalhosseini, Elham Hakimizadeh, Iman Fatemi

“…The final group was exposed to PQ aerosol and treated with oral dexamethasone at a dose of 0.03 mg/kg/day. Various hematological, oxidative, inflammatory, and pathological indices were measured at the conclusion of the treatment period. …”
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Clinical and diagnostic study of ovine chronic progressive pneumonia (Maedi-Visna) in sheep of Basrah, Iraq by Kamal M. AlSaad, Ali J. Lafta, Mohand H. Lafta, Jihad A. Ahmed

“…The suspected animals showed signs of chronic pneumonia, anorexia, emaciation, progressive emaciation, and chronic cough. 25 samples clinically healthy local breeds were served as a control group. 88 sheep were found positive for the specific IgG of Lentivirus with an infection rate 65.18% which was confirmed by the indirect ELISA test. Hematological analysis indicated a significant increase in ESR with significant leukocytopenia, lymphocytopenia, and monocytopenia, with clear differences in indices of clotting factors. …”
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Determinants of Deescalation Failure in Critically Ill Patients with Sepsis: A Prospective Cohort Study by Nawal Salahuddin, Lama Amer, Mini Joseph, Alya El Hazmi, Hassan Hawa, Khalid Maghrabi

“…On multivariate regression analysis, failure to deescalate was significantly predicted by hematologic malignancy OR 3.3 (95% CI 1.4–7.4) p<0.004, fungal sepsis OR 2.7 (95% CI 1.2–5.8) p=0.011, multidrug resistance OR 2.9 (95% CI 1.4–6.0) p=0.003, baseline serum procalcitonin OR 1.01 (95% CI 1.003–1.016) p=0.002, and SAPS II scores OR 1.01 (95% CI 1.004–1.02) p=0.006. …”
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Clinical Outcome Differences in Mucinous Versus Non-Mucinous Colonic Adenocarcinoma: A Comparative Study by Adrian Cote, Roxana Loriana Negrut, Hany Abdulateif Salem, Bogdan Feder, Mircea Gheorghe Pop, Adrian Marius Maghiar

“…No significant statistical differences were found regarding hematological parameters. However, MAC was associated with higher rates of local invasion and a predominant right-sided colonic location, necessitating more frequent right colectomies. …”
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Anti-VEGF therapy improves EGFR-vIII-CAR-T cell delivery and efficacy in syngeneic glioblastoma models in mice by Dai Fukumura, Rakesh K Jain, Jun Ren, Xinyue Dong, Zohreh Amoozgar, Somin Lee, Meenal Datta, Sylvie Roberge, Mark Duquette

“…Chimeric antigen receptor (CAR)-T cells have revolutionized the treatment of multiple types of hematological malignancies, but have shown limited efficacy in patients with glioblastoma (GBM) or other solid tumors. …”
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High and low dose radiotherapy combined with ICIs for MSS colorectal cancer patients with liver metastases: a phase I study (HaRyPOT) by Yuxuan Ding, Yong Feng, Yangfan Ye, Jiayi Shen, Chang Guo, Xia He, Liangjun Zhu, Lijun Wang

“…In exploratory endpoint analyses, tissue biopsies and paired hematologic samples from patients showed M2 macrophage reduction. …”
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Immunophenotypic Characterization of Human Bone Marrow Mast Cells. A Flow Cytometric Study of Normal and Pathological Bone Marrow Samples by Luis Escribano, Alberto Orfao, Jesús Villarrubia, Beatriz Díaz-Agustín, Carlos Cerveró, Agustín Rios, José L. Velasco, Juana Ciudad, José L. Navarro, Jesús F. San Miguel

“…The goal of the present paper was to define the immunophenotype of bone marrow mast cells (BMMC) from healthy controls and patients with hematologic malignancies (HM) based on the use of multiple stainings with monoclonal antibodies analyzed by flow cytometry. …”
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Alloreactivity of Allogeneic Mesenchymal Stem/Stromal Cells and Other Cellular Therapies: A Concise Review by Kiran Shah, Nirali Shah, Fatameh Ghassemi, Carolyn Ly, Teena George, Carla Lutz, Huseyin Sumer

“…The area has been further strengthened with the approval of Chimeric Antigen Receptor added on T cells (CAR-T) therapies by the regulatory authorities USA’s Food and Drugs Administration (FDA), European Medical Agency (EMA), the Australian Therapeutic Goods Administration (TGA), and in many countries in 2017 to treat hematological cancers. Another milestone was achieved when allogeneic Mesenchymal Stem Cell- (MSC-) based therapy was approved by the EMA to treat Chrohn’s disease in 2018. …”
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The influence of sex on sleep characteristics in the adult and older adult population: findings from the EPISONO sleep study by Mayra dos Santos Silva, Priscila Farias Tempaku, Priscila Farias Tempaku, Monica Levy Andersen, Monica Levy Andersen, Sergio Tufik, Sergio Tufik, Dalva Poyares, Dalva Poyares

“…They also underwent full-night polysomnography (PSG) and peripheral blood collection for biochemical and hematological measurements. In both editions (2007 and 2015), physical and anthropometric assessments were also assessed. …”
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Positive association between chronic hepatitis B virus infection and anemia in pregnancy in Southern China by Renliang Huang, Zhe Lu, Xinze Li, Duo Zhou, Jing Xu, Dan Lin, Yunxue Fu, Yan Liang, Xuexia Li, Frank Petersen, Qiaomiao Zhou, Xinhua Yu

“…Further analysis unveiled distinctive hematological alterations among cases with chronic hepatitis B virus infection, characterized by diminished erythrocyte size and reduced levels of corpuscular hemoglobin. …”
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Effect of Praziquantel on Preventing Delayed Infection of <i>Schistosoma japonicum</i> in Buffaloes and Goats by Xiang Gui, Bing Shao, Haoran Zhong, Rongxue Lv, Hao Li, Ke Lu, Yang Hong, Zhiqiang Fu, Zhenjie Lu, Mengge Xu, Yamei Jin, Jinming Liu

“…This study aimed to evaluate the efficacy of PZQ in preventing <i>S. japonicum</i> infection in buffaloes and goats via assessing worm burden, worm size, hematological changes, and immune modulation. In the present study, buffaloes and goats were pretreated with PZQ at various doses (7–25 mg/kg body weight), followed by infection with <i>S. japonicum</i> cercariae. …”
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The molecular receptor NKBB enhances the persistence and anti-hepatocellular carcinoma activity of GPC3 CAR-T cells by Minghao Sui, Tiantian Liu, Xuanli Song, Ji Li, Han Ding, Yuqian Liu, Xinyu Wang, Huimin Liu, Yuchan Xue, Jianni Qi, Miao Zhang, Songbo Zhao, Qiang Zhu

“…Chimeric antigen receptor (CAR) T cells have encouraging results in the treatment of hematological malignancies. However, CAR-T therapy still faces numerous challenges against solid tumors, such as hepatocellular carcinoma (HCC), owing to heterogeneous antigen expression in tumor cells, limited persistence of CAR-T cells, etc. …”
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Cobalamin and Folic Acid Status in Relation to the Etiopathogenesis of Pancytopenia in Adults at a Tertiary Care Centre in North India by M. Premkumar, N. Gupta, T. Singh, T. Velpandian

“…We investigated the clinical, etiological and hematological profile including bone marrow morphology of patients with pancytopenia in relation to their vitamin B12 and folic acid status at a tertiary care referral hospital in north India. …”
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A Case of Undiagnosed HIV Infection in a 57-Year-Old Woman with Multiple Myeloma: Consequences on Chemotherapy Efficiency and Safety by I. Poizot-Martin, S. Brégigeon, C. Tamalet, R. Bouabdallah, O. Zaegel-Faucher, V. Obry-Roguet, A. Ivanova, C.E. Cano, C. Solas

“…A 57-year-old woman diagnosed with multiple myeloma underwent a first round of chemotherapy by bortezomib/lenalidomide and then with bortezomib/liposomal-doxorubicine/dexamethasone, with partial remission, poor hematological tolerance, and multiple episodes of pneumococcal infection. …”
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Analisis Unit Cost Pelayanan Unit Laboratorium Rumah Sakit Naili DBS Tahun 2017 dengan Metode Activity Based Costing (ABC) by Ressa Oasthttamadea, Menkher Manjas, Yurniwati Yurniwati

“…Hasil penelitian kuantitatif menunjukkan bahwa perhitungan unit cost pelayanan laboratorium dengan metode ABC pada pemeriksaan hematologi rutin dan waktu pembekuan & pendarahan memberikan hasil yang lebih rendah dibandingkan tarif rumah sakit (Rp 45.389,- dan Rp 33.904,-), dan kebalikannya pada pemeriksaan gula darah random (Rp 33.904,-). …”
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Actinidia deliciosa as a complemental therapy against nephropathy and oxidative stress in diabetic rats by Ali Y. Naoom, Wenyi Kang, Nora F. Ghanem, Mohamed M. Abdel-Daim, Fatma M. El-Demerdash

“…Elevation in blood sugar level, lipid peroxidation (LPO), kidney function biomarkers, and perturbations in hematological parameters were observed in diabetic rats. …”
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