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Integrated Microbiome and Metabolome Analysis Reveals Correlations Between Gut Microbiota Components and Metabolic Profiles in Mice With Mitoxantrone-Induced Cardiotoxicity
Published 2025-01-01“…Qing Zhang,1 Deshuai Liang,2 Chengfang Zhang,3 Ling Ye,4 Ping Sun,4 Hongli Zhu,4 Yongqin Zhao,4 Yuewen Li,4 Yun Guan,4 Haiguo Zhang4 1College of Clinical Medicine, Jining Medical University, Jining, 272013, People’s Republic of China; 2Department of Pharmacy, Jining NO. 1 People’s Hospital, Jining, 272000, People’s Republic of China; 3Department of Clinical Laboratory, Jining NO. 1 People’s Hospital, Jining, 272000, People’s Republic of China; 4Department of Hematology, Jining NO. 1 People’s Hospital, Jining, 272000, People’s Republic of ChinaCorrespondence: Haiguo Zhang; Yun Guan, Jining NO. 1 People’s Hospital, 6 Jiankang Road, Jining Shandong, 272000, People’s Republic of China, Tel/Fax +86-0537 2257626 ; +86-0537 2087093, Email wfmchero@126.com; gyuanun1989@163.comPurpose: Mitoxantrone (MTX) is largely restricted in clinical usage due to its significant cardiotoxicity. …”
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MUC2 expression modulates immune infiltration in colorectal cancer
Published 2025-01-01Get full text
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The Role of Immunohistochemistry for AMACR/p504s and p63 in Distinguishing Prostate Cancer from Benign Prostate Tissue Samples in Botswana
Published 2025-01-01“…Pleasure Ramatlho,1,2 Moses Muganyizi Rugemalila,3 Leabaneng Tawe,1,2 Debanjan Pain,4,5 Ontlametse T Choga,1,6 Andrew Khulekani Ndlovu,1 Moses O Koobotse,1 Priti Lal,5 Timothy R Rebbeck,7,8 Giacomo M Paganotti,2,9 Mohan Narasimhamurthy,5 Lynnette Tumwine Kyokunda3 1School of Allied Health Professions, Faculty of Health Sciences, University of Botswana, Gaborone, Botswana; 2Botswana-University of Pennsylvania Partnership, Gaborone, Botswana; 3Department of Pathology, Faculty of Medicine, University of Botswana, Gaborone, Botswana; 4Department of Medicine (Hematology-Oncology), University of Pennsylvania, Philadelphia, PA, USA; 5Hospital of University of Pennsylvania, Philadelphia, PA, USA; 6Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; 7Division of Population Science, Dana-Farber Cancer Institute, Boston, MA, USA; 8Department of Epidemiology, Harvard T.H. …”
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Genotype-Phenotype Correlation of G6PD Mutations among Central Thai Children with G6PD Deficiency
Published 2021-01-01“…Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common X-linked inherited erythroenzymopathy in Thailand. The clinical and hematological manifestations of G6PD deficiency are variable. …”
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Unraveling complexity and leveraging opportunities in uncommon breast cancer subtypes
Published 2025-01-01Get full text
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Systemic delivery of AAV5, AAV8, and AAV9 packaging a C5-12-microdystrophin-FLAG expression cassette in non-human primates
Published 2025-03-01“…The AAV8-microdystrophin-FLAG led to ∼20% of wild-type NHP dystrophin protein expression levels and was located on the sarcolemma of ∼40% of skeletal muscles fibers and ∼15% of left ventricular cardiomyocytes. Hematology, serum chemistry, and pathology were unremarkable. …”
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Associations between disease severity, depression, health-related quality of life, and physical activity in adults with sickle cell disease
Published 2025-01-01“…Methods A total of 385 patients with SCD (mean age 35.45 ± 12.01 years; 51.70% female) attending hematology clinics in two Nigerian tertiary hospitals participated in this cross-sectional study. …”
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2079
Polygenic height prediction for the Han Chinese in Taiwan
Published 2025-02-01Get full text
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2080