Assessing greenhouse gas emissions in hospitals: The development of an open-access calculator and its application to a German case-study by Claudia Quitmann, Leonard Terres, Andy Maun, Rainer Sauerborn, Emma Reynolds, Till Bärnighausen, Alina Herrmann, Bernd Franke

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Pancreatic resection with perioperative drug repurposing of propranolol and etodolac: trial protocol of the phase-II randomised placebo controlled PROSPER trial by Phillip Knebel, Thilo Hackert, Markus W Büchler, Ilse Rooman, Markus K Diener, Felix J Hüttner, André L Mihaljevic, Oliver Strobel, Gauthier Bouche, Johannes Hüsing

“…The clinical trial is accompanied by a translational study investigating the mechanisms of action of the combined therapy on a molecular basis.Ethics and dissemination The PROSPER-trial has been approved by the German Federal Institute for Drugs and Medical Devices (reference number 4042875) and the Ethics Committee of the Medical Faculty of the University of Heidelberg (reference number AFmo-385/2018). The final trial results will be published in a peer-reviewed journal and will be presented at appropriate national and international conferences.Trial registration numbers DRKS00014054; EudraCT number: 2018-000415-25.…”
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A perfusion-independent high-throughput method to isolate liver sinusoidal endothelial cells by Anna Babin-Ebell Gonçalves, Yifang Mao, Tinja Baljkas, Felix Wiedmann, Larissa Eis, Franziska Pilz, Manuel Winkler, Sina W. Kürschner-Zacharias, Marlene Hoffarth, Charlotta Funaya, Réza Shahidi, Cyrill Géraud, Chi-Chung Wu, Constanze Schmidt, Sergij Goerdt, Philipp-Sebastian Reiners-Koch, Mahak Singhal

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Reduced Serum Butyrylcholinesterase Activity Indicates Severe Systemic Inflammation in Critically Ill Patients by Aleksandar R. Zivkovic, Karsten Schmidt, Annette Sigl, Sebastian O. Decker, Thorsten Brenner, Stefan Hofer

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Detection of other pathologies when utilising computer-assisted digital solutions for TB screening by J. Sebastian, I.D. Olaru, A. Giannakis, M. Arentz, S.V. Kik, M. Ruhwald, S. Linsen, G. Günther, P. Wolf, F.J. Herth, T. Weber, C.M. Denkinger

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Elevation of Platelet and Monocyte Activity Markers of Atherosclerosis in Haemodialysis Patients Compared to Peritoneal Dialysis Patients by Ksenija Stach, Susanne Karb, Ibrahim Akin, Martin Borggrefe, Bernhard Krämer, Thorsten Kälsch, Anna-Isabelle Kälsch

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Reactive Metabolites and AGE-RAGE-Mediated Inflammation in Patients following Liver Transplantation by Thorsten Brenner, Thomas H. Fleming, David Spranz, Peter Schemmer, Thomas Bruckner, Florian Uhle, Eike O. Martin, Markus A. Weigand, Stefan Hofer

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Patients with Multiple Functional Gastrointestinal Disorders (FGIDs) Show Increased Illness Severity: A Cross-Sectional Study in a Tertiary Care FGID Specialty Clinic by Sabrina Berens, Felicitas Engel, Annika Gauss, Jonas Tesarz, Wolfgang Herzog, Beate Niesler, Esther Stroe-Kunold, Rainer Schaefert

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CD4+CD25highCD127low Regulatory T Cells in Peripheral Blood Are Not an Independent Factor for Chronic Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation by Jolanta B. Perz, Selma Gürel, Stefan O. Schonland, Ute Hegenbart, Anthony D. Ho, Peter Dreger

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Biomarkers in alcohol use disorder - The promise and pitfalls of neuroimaging drug cue reactivity by Marlen Pfisterer, Sina Zimmermann, Judith Zaiser, Sarah Gerhardt, Sabine Vollstädt-Klein, Falk Kiefer, Patrick Bach

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Scalable network emulation on analog neuromorphic hardware by Elias Arnold, Philipp Spilger, Jan V. Straub, Eric Müller, Dominik Dold, Gabriele Meoni, Johannes Schemmel

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Genomic Instability in Context of the Chromosomal Theory by Alice Fabarius, Peter Duesberg, Michelle Giehl, Wolfgang Seifarth, Andreas Hochhaus, Rüdiger Hehlmann

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Opportunistic bone density assessment using pre-treatment [18F]FDG-PET/CT identifies fracture risk in lymphoma patients undergoing corticosteroid-containing chemotherapy by Genevieve Douglas, Kane M. Nicholls, Erin Paul, Zoe Loh, Sze-Ting Lee, Kathryn L Hackman, Cherie Chiang, Niamh Waters, Geoffrey Chong, Ashvind Prabahran, Eliza A. Hawkes

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Ion Channel Expression and Characterization in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Zhihan Zhao, Huan Lan, Ibrahim El-Battrawy, Xin Li, Fanis Buljubasic, Katherine Sattler, Gökhan Yücel, Siegfried Lang, Malte Tiburcy, Wolfram-Hubertus Zimmermann, Lukas Cyganek, Jochen Utikal, Thomas Wieland, Martin Borggrefe, Xiao-Bo Zhou, Ibrahim Akin

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The CNDP1 (CTG)5 Polymorphism Is Associated with Biopsy-Proven Diabetic Nephropathy, Time on Hemodialysis, and Diabetes Duration by Thomas Albrecht, Shiqi Zhang, Jana D. Braun, Li Xia, Angelica Rodriquez, Jiedong Qiu, Verena Peters, Claus P. Schmitt, Jacob van den Born, Stephan J. L. Bakker, Alexander Lammert, Hannes Köppel, Peter Schnuelle, Bernhard K. Krämer, Benito A. Yard, Sibylle J. Hauske

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Mesenchymal Stromal Cells from Osteoarthritic Synovium Are a Distinct Population Compared to Their Bone-Marrow Counterparts regarding Surface Marker Distribution and Immunomodulati... by Sebastien Hagmann, Claudia Rimmele, Florin Bucur, Thomas Dreher, Felix Zeifang, Babak Moradi, Tobias Gotterbarm

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The Macrophage Inflammatory Proteins MIP1α (CCL3) and MIP2α (CXCL2) in Implant-Associated Osteomyelitis: Linking Inflammation to Bone Degradation by Ulrike Dapunt, Susanne Maurer, Thomas Giese, Matthias Martin Gaida, Gertrud Maria Hänsch

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Protocol for isolating and purifying murine liver sinusoidal endothelial cells for in vitro culture and functional assays by Sophia Papaioannou, Jia-Xiang See, Tinja Baljkas, Philipp Reiners-Koch, Manuel Winkler, Adelheid Cerwenka, Ana Stojanovic

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Prophylactic Administration of Surfactant in Extremely Premature Infants by Lutz Koch, David Frommhold, Bernd Beedgen, Peter Ruef, Johannes Poeschl

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Self-reported determinants for subjective financial distress: a qualitative interview study with German cancer patients by Eva Winkler, Katja Mehlis, Bastian Surmann, Wolfgang Greiner, Andrea Züger, Viktoria Mathies, Sophie Pauge, Luise Richter, Thomas Ernst, Natalja Menold

“…The interviews were audiorecorded, transcribed verbatim and analysed using qualitative content analysis.Setting Participants were recruited from two German academic cancer centres, that is, the National Center for Tumor Diseases Heidelberg and Jena University Hospital.Participants 18 patients who had undergone cancer-related therapy for at least 2 months were interviewed (10 females).Results Based on the results of the qualitative content analysis, we developed a multicomponent construct of determinants that could influence subjective financial distress. …”
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