Adjuvant Use of Ivabradine in Acute Heart Failure due to Myocarditis by Jennifer Franke, Dorothee Schmahl, Stephanie Lehrke, Regina Pribe, Raffi Bekeredjian, Andreas O. Doesch, Philipp Ehlermann, Philipp Schnabel, Hugo A. Katus, Christian Zugck

“…The patients had been transferred to the intensive care unit (ICU) with commencing symptoms of acute heart failure and consecutive multiorgan failure for further treatment and to evaluate the indication for implantation of a ventricular assist device or for high urgent orthotopic heart transplantation. In both patients, the If-channel inhibitor ivabradine was administered off-label to provide selective heart rate reduction, and thus support hemodynamic stabilization. …”
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Current Practice of Heart Donor Evaluation in Germany: Multivariable Risk Factor Analysis Confirms Practicability of Guidelines by Sylke Ruth Zeissig, Carl-Ludwig Fischer-Froehlich, Frank Polster, Nils R. Fruehauf, Guenter Kirste, Irene Schmidtmann

“…Organ shortage has liberalised the acceptance criteria of grafts for heart transplantation, but which donor characteristics ultimately influence the decision to perform transplantation? …”
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Advanced heart failure: guideline‐directed medical therapy, diuretics, inotropes, and palliative care by Daniela Tomasoni, Julie K.K. Vishram‐Nielsen, Matteo Pagnesi, Marianna Adamo, Carlo Mario Lombardi, Finn Gustafsson, Marco Metra

“…Only a limited proportion of these patients can undergo heart transplantation or mechanical circulatory support. …”
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Utilization of Cardiac Magnetic Resonance Imaging for Assessing Myocardial Fibrosis in Prognosis Evaluation and Risk Stratification of Patients with Dilated Cardiomyopathy by Xin-Yi Feng, Yu-Cong Zheng, Ying-Xia Yang, Wen-Feng He, Fan Yang, Ling-Li Wang, Han-Feng Yang, Chun-Ping Li, Xiao-Xue Xu, Rui Li

“…DCM can ultimately lead to heart failure, ventricular arrhythmia (VA), and sudden cardiac death (SCD), making it a primary indication for heart transplantation. With advancements in modern medicine, several novel techniques for evaluating myocardial involvement and disease severity from diverse perspectives have been developed. …”
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Gene Expression Signatures of Peripheral Blood Mononuclear Cells during the Early Post-Transplant Period in Patients Developing Cardiac Allograft Vasculopathy by Khurram Shahzad, Martin Cadeiras, Sarfaraz Memon, Barry Zeeberg, Tod Klingler, Anshu Sinha, Esteban G. Tabak, Sreevalsa Unniachan, Mario C. Deng

“…Cardiac allograft vasculopathy (CAV) is a major cause of graft loss and death after heart transplantation. Currently, no diagnostic methods are available during the early post-transplant period to accurately identify patients at risk of CAV. …”
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Severe primary graft failure: Are there lasting impacts? Analysis from the PHTS Database by Jennifer Conway, MD, Tara Pidborochynski, MSc, James K. Kirklin, MD, Ryan Cantor, PhD, Hong Zhao, PhD, Aryaz Sheybani, MD, Jacqueline Lamour, MD, Lakshmi Gokanapudy Hahn, MD, Leslie Collins, MD, Jessica Laks, MD, Darren H. Freed, MD, PhD

“…Background: Primary graft failure (PGF) is a leading cause of early morbidity and mortality after heart transplantation (HTx). PGF is secondary to graft ischemia and ischemia-reperfusion injuries to the cardiomyocytes and vasculature of the donor heart after transplantation. …”
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Prevalence, management, and outcomes of haemorrhagic events in left ventricular assist device recipients by Laetitia Pourtau, Maxime Beneyto, Jean Porterie, Jerome Roncalli, Montse Massot, Caroline Biendel, Pauline Fournier, Romain Itier, Michel Galinier, Olivier Lairez, Clement Delmas

“…Bleeding events, death, and heart transplantation were collected from electronic medical files. …”
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Outcome differences in acute vs. acute on chronic heart failure and cardiogenic shock by Tara L. Jones, Michael C. Tan, Vidang Nguyen, Kathleen E. Kearney, Charles C. Maynard, Emily Anderson, Claudius Mahr, James M. McCabe

“…Secondary outcomes were use of temporary mechanical circulatory support, durable ventricular assist device implantation, total artificial heart implantation, or heart transplantation. Comparison of continuous variables was performed using Student's t‐test. …”
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Impact of antiviral prophylaxis on EBV viremia and posttransplant lymphoproliferative disorders in solid organ transplant recipients: a systematic review and meta-analysis by Marjan Moghadamnia, Khadijeh Delroba, Shima Heidari, Zahra Rezaie, Simin Dashti-Khavidaki

“…Administration of antiviral prophylaxis can significantly reduce the incidence of PTLD among kidney (RR 0.63, 95% CI 0.46 to 0.87) and heart transplant patients (RR 0.61, 95% CI 0.39 to 0.96). …”
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Outcome and prognostic value of N‐terminal pro‐brain natriuretic peptide and high‐sensitivity C‐reactive protein in mildly dilated cardiomyopathy vs. dilated cardiomyopathy by Jiayu Feng, Pengchao Tian, Lin Liang, Yuyi Chen, Yunhong Wang, Mei Zhai, Yan Huang, Qiong Zhou, Xuemei Zhao, Lang Zhao, Boping Huang, Liyan Huang, Yuhui Zhang, Jian Zhang

“…Compared with DCM, patients with baseline MDCM had lower composite risks of all‐cause mortality, heart transplantation, and heart failure rehospitalization [adjusted hazard ratio (HR) 0.63, 95% confidence interval (CI) 0.43–0.93, P = 0.019]. …”
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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…[ix]  Wang, W., et al., “First Pig-to-Human Heart Transplantation,” Innovation (Camb) 3, no. 2 (2022): 100223. …”
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Indocyanine Green Lymphography-guided Ligation to Treat ECMO-related Groin Lymphocele by Albert Lamas Llopis, Sergi Barrantes, Laura Torrano Romero, Silvia de la Torre González, Luís Martínez-Sapiña, JA Palacín Porté, Anna López Ojeda

“…Extracorporeal Membrane Oxygenation (ECMO) placement in heart transplant patients can lead to the development of a groin lymphocele. …”
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Primary Angioplasty for Cardiac Allograft Vasculopathy Presenting as ST-Elevation Acute Myocardial Infarction during Endomyocardial Biopsy by Bruno Ramos Nascimento, Thalles Oliveira Gomes, Júlio César Borges, Guilherme Rafael Sant’Anna Athayde, Sílvio Amadeu de Andrade, Maria da Consolação Vieira Moreira

“…Cardiac allograft vasculopathy is still a major issue, with significative mortality in heart transplant patients, and the best therapeutic options are not yet established. …”
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Voriconazole-induced periostitis in the hand by Gurbinder Singh, Daria Motamedi, Kevin Sweetwood

“…This case report details a 65-year-old male on chronic immunosuppressive and antimicrobial therapy following heart transplant who developed hand pain. Identification of periostitis on hand radiographs and an acute elevation of alkaline phosphatase on subsequent blood analysis prompted discontinuation of voriconazole, resulting in a symptomatic and laboratory improvement. …”
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A Predictive Model for Super-Response to Cardiac Resynchronization Therapy: The QQ-LAE Score by Xi Liu, Yiran Hu, Wei Hua, Shengwen Yang, Min Gu, Hong-Xia Niu, Li-Gang Ding, Jing Wang, Shu Zhang

“…Multivariate Cox proportional-hazard regression analysis was conducted to assess associations with the long-term endpoint (defined as cardiac death/heart transplant, heart failure (HF) hospitalization, or all-cause death) across the score categories at follow-up. …”
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Partial Nephrectomy in a Patient with a Left Ventricular Assist Device by Jules P. Manger, John A. Kern, Tracey L. Krupski

“…Left ventricular assist device (LVAD) use has increased as a bridge to heart transplant as well as destination therapy in patients with severe heart failure. …”
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Acute Pancreatitis after Colonoscopy: A Case Presentation and Literature Review by Sahil D. Doshi, Yelina Alvarez, Shria Kumar, Octavia Pickett-Blakely

“…A 51-year-old male with a left ventricular assist device for end-stage nonischemic cardiomyopathy and a family history of colorectal cancer was admitted for an expedited heart transplant evaluation. He underwent screening colonoscopy during this admission which was technically uncomplicated apart from requiring slight maneuvering at the splenic flexure. …”
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Potential Infectious Complications in Pig Xenograft Donors and Recipients by Nicolas J. Mueller, Linda Scobie

“…Preclinical trials involving pig kidneys and hearts transplanted into various non-human primates have revealed the potential impact of pig pathogens being present in the transplanted organ/tissue, mainly viruses. …”
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Left Ventricular Assist Devices – Past, Present, and Future: A Narrative Review by Devesh Kumar, Sandeep Seth, Rajiv Narang

“…Advanced heart failure (AHF) is a major problem with an aging population and profound unmet needs. While heart transplant offers the most definitive solution, it is largely unavailable for most and mandates a long waiting period. …”
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Atypical presentation of Andersen-Tawil syndrome: heart failure with reduced ejection without periodic paralysis or dysmorphic features by Mustafa Shehzad, Dawood Shehzad, Muhammad Ahmad, Sundus Huma, Shaheer Minhas, Abdul Wassey

“…Currently, the patient remains on guideline-directed medical therapy and is listed for a heart transplant. Conclusions: Dilated cardiomyopathy, although a rare manifestation in ATS, can profoundly increase the risk of fatal arrythmias, necessitating the need for a low threshold of suspicion, to ensure timely diagnosis and management.…”
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