Physiological and pathological roles of PGAM5: An update and future trend by Weibin He, Wenlong He, Zhongchan Sun, Pengcheng He

Get full text

Exendin-4 Protects against Hyperglycemia-Induced Cardiomyocyte Pyroptosis via the AMPK-TXNIP Pathway by Hong Wei, Rui Bu, Qinghui Yang, Jing Jia, Tao Li, Qiuping Wang, Yanjun Chen

“…Diabetic cardiomyopathy is a common cardiac condition in patients with diabetes mellitus, which results in cardiac hypertrophy and subsequent heart failure. Chronic inflammation in the diabetic heart results in loss of cardiomyocytes and subsequentially cardiac dysfunction. …”
Get full text

Helicobacter pylori Eradication in Idiopathic Thrombocytopenic Purpura: A Meta-Analysis of Randomized Trials by Bum Jun Kim, Hyeong Su Kim, Hyun Joo Jang, Jung Han Kim

Get full text

Acute electrocardiographic changes during smoking: an observational study by Balram Bhargava, Sandeep Singh, Ambuj Roy, Sivasubramanian Ramakrishnan, Nitish Naik, Kinjal Bhatt, Akhilesh K Dubey, Sandeep Seth

“…A total of 31 such patients aged 49.8±10.5 years, in whom TMT was either negative or mildly positive were included. Heart rate variability (HRV) parameters of smokers were compared to those of 15 healthy non-smoking participants.Interventions All patients underwent a 24 h Holter monitoring to assess ECG changes during smoking periods.Results Heart rate increased acutely during smoking. …”
Get full text

Recent Developments in Ventricular Assist Device Therapy by Angel Moctezuma-Ramirez, Haseeb Mohammed, Austin Hughes, Abdelmotagaly Elgalad

“…Pediatric ventricular assist devices (VADs) remain a critical unmet need; challenges in developing pediatric VADs include device sizing and managing congenital heart disease. Advances in LVAD technology adapted for use in right ventricular assist devices (RVADs) make possible the effective management of right ventricular failure in patients with acute cardiac conditions or congenital heart defects. …”
Get full text

Protein Disulfide Isomerase and Host-Pathogen Interaction by Beatriz S. Stolf, Ioannis Smyrnias, Lucia R. Lopes, Alcione Vendramin, Hiro Goto, Francisco R. M. Laurindo, Ajay M. Shah, Celio X. C. Santos

Get full text

Automated MSCT Analysis for Planning Left Atrial Appendage Occlusion Using Artificial Intelligence by Kilian Michiels, Eva Heffinck, Patricio Astudillo, Ivan Wong, Peter Mortier, Alessandra Maria Bavo

“…The number of multislice computed tomography (MSCT) analyses performed for planning structural heart interventions is rapidly increasing. Further automation is required to save time, increase standardization, and reduce the learning curve. …”
Get full text

A Novel Myosin Essential Light Chain Mutation Causes Hypertrophic Cardiomyopathy with Late Onset and Low Expressivity by Paal Skytt Andersen, Paula Louise Hedley, Stephen P. Page, Petros Syrris, Johanna Catharina Moolman-Smook, William John McKenna, Perry Mark Elliott, Michael Christiansen

Get full text

Cirrhotic cardiomyopathy by S. N. Mammayev, A. M. Karimova, T. E. Il’yasova, A. Sh. Khasayev

“…Development of heart failure (HF) decompensation due to provoking factors action requires application of the standard therapeutic approaches to treatment of such patients. …”
Get full text

Cardiogenic Shock and Guillain–Barré Syndrome as the First Manifestations of Pheochromocytoma by Maryam Heidarpour, Nafiseh Sereshti, Davood Shafie, Bijan Iraj, Hassan Rezvanian

“…Febrile congestive heart failure is a rare first manifestation of pheochromocytoma. …”
Get full text

Isolated Interrupted Aortic Arch: Unexpected Diagnosis in a 63-Year-Old Male by Hassan Javadzadegan, Jahan Porhomayon, Alireza Sadighi, Mehrdad Yavarikia, Nader Nader

“…Femoral and popliteal pulses were extremely weak, and third (S3) and fourth (S4) heart sounds were audible. Aortography showed a mildly dilated aortic root with double brachiocephalic trunk and interruption of aortic arch at isthmus. …”
Get full text

Clinical approach to palpitations in pregnancy by Ferha Saeed, Kirun Gunganah, Anna S. Herrey

“…If the patient is stable, medical management is indicated, and early involvement of the pregnancy heart team can help facilitate appropriate treatment. …”
Get full text

MicroRNA in Diabetic Nephropathy: Renin Angiotensin, AGE/RAGE, and Oxidative Stress Pathway by Shinji Hagiwara, Aaron McClelland, Phillip Kantharidis

Get full text

Frequency Of Raised Mean Platelet Volume In Patients With Acute Coronary Syndrome In HIT Hospital Taxila by Faiza Batool, Kausar Malik, Lubna Meraj, Khalid Mehmood Tariq, Tooba Iqbal, Neelum Zaka

“…The patients included in the control group (non-ACS group) had chest pain without having ischemic heart disease or risk of ischemic heart disease. …”
Get full text

Validity, Accuracy, and Safety Assessment of an Aerobic Interval Training Using an App-Based Prehabilitation Program (PROTEGO MAXIMA Trial) Before Major Surgery: Prospective, Inter... by Sara Fatima Faqar Uz Zaman, Svenja Sliwinski, Lisa Mohr-Wetzel, Julia Dreilich, Natalie Filmann, Charlotte Detemble, Dora Zmuc, Felix Chun, Wojciech Derwich, Waldemar Schreiner, Wolf Bechstein, Johannes Fleckenstein, Andreas A Schnitzbauer

“…During the exercise, patients wore app-linked wearables for heart rate and distance measurements, which were compared with standard ECG and treadmill measurements. …”
Get full text

Echocardiography indicators in patients with atherosclerosis of peripheral arteries of the lower extremities dependent on T(–786)C polymorphism of the endothelial nitric oxide synt... by V.I. Tseluyko, O.D. Yarova

“…Patients were divided into two clinical groups: group I – 63 (63 %) men without coronary heart disease, group II – 37 (37 %) patients with CHD. …”
Get full text

A smartphone-guided secondary prevention digital health application reduces systolic blood pressure in patients with chronic coronary syndrome and insufficient blood pressure contr... by Philip Düsing, Stephan H. Schirmer, Sebastian Schäfer, Alexander Krogmann, Jan-Malte Sinning, Nikos Werner, Florian Bönner, Alexander Sedaghat, Cornelius Müller, Irina Eckardt, Georg Nickenig, Andreas Zietzer

Get full text

Echocardiographic phenotypes of diabetic myocardial disorder: evolution over 15 months follow-up in the ARISE-HF trial by Thomas H. Marwick, Carolyn Lam, Yuxi Liu, Stefano Del Prato, Julio Rosenstock, Javed Butler, Justin Ezekowitz, Nasrien E. Ibrahim, W. H. Wilson Tang, Faiez Zannad, Riccardo Perfetti, James L. Januzzi

“…Abstract Background Diabetic myocardial disorder (DbMD, evidenced by abnormal echocardiography or cardiac biomarkers) is a form of stage B heart failure (SBHF) at high risk for progression to overt HF. …”
Get full text

Comprehensive profiling of serum microRNAs in normal and non-alcoholic fatty liver disease (NAFLD) patients by Jian-Wei Zhang, Kamran Ullah, Nauman Khan, Hai-Tao Pan

“…NAFLD can also directly contribute to heart problems through inflammation and insulin resistance, even in individuals without other risk factors. …”
Get full text

Microvascular dysfunction in a murine model of Alzheimer’s disease using intravital microscopy by Danielle Sidsworth, Noah Tregobov, Noah Tregobov, Colin Jamieson, Jennifer Reutens-Hernandez, Joshua Yoon, Geoffrey W. Payne, Geoffrey W. Payne, Stephanie L. Sellers, Stephanie L. Sellers, Stephanie L. Sellers, Stephanie L. Sellers

Get full text