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4921
Inhibition of Notch Signaling Promotes the Differentiation of Epicardial Progenitor Cells into Adipocytes
Published 2021-01-01“…Frozen sections of C57BL/6J mouse hearts were used to observe epicardial adipose tissue (EAT), and genetic lineage methods were used to trace EPCs. …”
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4922
Hydroxytyrosol Protects against Myocardial Ischemia/Reperfusion Injury through a PI3K/Akt-Dependent Mechanism
Published 2016-01-01“…To investigate the effects and mechanisms of hydroxytyrosol (HT) during the pathogenesis of myocardial ischemia reperfusion (I/R) in rat hearts. Methods. The rats were randomized into five groups: sham group, I/R group, HT+I/R group, HT+LY294002+I/R group, and LY+I/R group. …”
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4923
Research on smart city construction in the context of public culture
Published 2025-03-01“…Based on this framework, six recommendations are proposed for the development of public cultural initiatives in smart cities to enhance their positive impact on urban development, and to provide a new perspective for promoting the construction of a better and more warm-hearted smart city.…”
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4924
Cardiomyocyte-Restricted Deletion of PPARβ/δ in PPARα-Null Mice Causes Impaired Mitochondrial Biogenesis and Defense, but No Further Depression of Myocardial Fatty Acid Oxidation...
Published 2011-01-01“…Moreover, PPARα-null did not alter the phenotypic development in adult mice with the short-term deletion of PPARβ/δ in their hearts, which showed mitochondrial abnormalities, depressed cardiac performance, and cardiac hypertrophy with attenuated expression of key factors in mitochondrial biogenesis and defense. …”
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4925
MicroRNA-208a Dysregulates Apoptosis Genes Expression and Promotes Cardiomyocyte Apoptosis during Ischemia and Its Silencing Improves Cardiac Function after Myocardial Infarction
Published 2015-01-01“…At 7 and 28 days, echocardiography was done and thereafter hearts were harvested for analysis of apoptosis by TUNEL method, fibrosis using Masson’s trichrome, and hypertrophy using hematoxylin and eosin. miR-208a altered apoptosis genes expression and increased apoptosis in ischemic cardiomyocytes. …”
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4926
Quercetin Inhibits Pyroptosis in Diabetic Cardiomyopathy through the Nrf2 Pathway
Published 2022-01-01“…We evaluated the protective effects of quercetin against diabetic cardiomyopathy by analyzing the expression of pyroptosis pathway proteins, myocardial cell apoptosis rate, degree of myocardial fibrosis, and serum inflammatory indices in the hearts of model rats with diabetes. We evaluated the expression of Nrf2 in the nucleus of cardiomyocytes and H9C2 cells to clarify the role of quercetin in promoting the nuclear translocation of Nrf2. …”
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4927
Acting Performance Evaluation Governor of Aceh in 2022 Based on Key Performance Indicators (KPIs) : Key Performance Indicators (KPIs), Acting Governor of Aceh: Achmad Marzuki, Stra...
Published 2024-02-01“…Since June 2022, Aceh Province has become a new chapter of leadership after the Helsinki MoU from the Military, this is in contrast to the message of the struggle, that the Military has a place in the hearts of the Acehnese people. So the presence of the military in the Aceh leadership system is interesting to study from its performance during its tenure. …”
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4928
The Multistream Self: Biophysical, Mental, Social, and Existential
Published 2008-01-01“…Four common fears of isolation, insecurity, insignificance, and death can be overcome by developing a lifestyle of whole-hearted engagement in the present reality, creative problem solving, self-actualization, and altruism. …”
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4929
Attenuation of Myocardial Injury by HMGB1 Blockade during Ischemia/Reperfusion Is Toll-Like Receptor 2-Dependent
Published 2013-01-01“…Injection of HMGB1 did, however, not increase infarct size in WT animals. In TLR2−/−-hearts, neither BoxA nor HMGB1 affected infarct size. …”
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4930
Periconceptional Undernutrition in Sheep Affects Adult Phenotype Only in Males
Published 2012-01-01“…Compared with N animals, male, but not female, offspring of all UN groups had greater % fat mass (all UN versus N: 9±1 versus 2±1%, P<0.001) and perirenal fat (544±36 versus 222±44 g, P=0.002), and proportionately smaller hearts (4.5±0.1 versus 5.2±0.2 g·kg−1), lungs (9.1±0.2 versus 10.6±0.5 g·kg−1), and adrenals (0.06±0.002 versus 0.08±0.003 g·kg−1). …”
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4931
Human-Gorilla and Gorilla-Human: Dynamics of Human-animal boundaries and interethnic relationships in the central African rainforest
Published 2014-02-01“…The dual nature of dzil-elizaliza expresses a contrast between the witch-controlled man-eater and the warm-hearted reincarnated ancestral relative in a human-gorilla. …”
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4932
Molecular study of the status of Angiostrongylus cantonensis in rats in Haiti
Published 2024-01-01“…Rats were trapped at 8 sites, 7 in Artibonite (rural region) and one in an urban area of Port-au-Prince. After euthanasia, hearts and lungs were sampled and preserved in 70% ethanol. …”
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4933
Normothermic Crystalloid Polarizing Cardioplegia Improves Systolic and Diastolic Function in a Porcine Model of Cardiopulmonary Bypass
Published 2024-12-01“…Myocardial injury (arterial CK-MB), hemodynamic function, and the energy status of the hearts were measured; Results: The arterial release of CK-MB was comparable between groups (<i>p</i> = 0.78) during reperfusion. …”
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4934
Compliance with ethical standards in the reporting of donor sources and ethics review in peer-reviewed publications involving organ transplantation in China: a scoping review
Published 2019-02-01“…Objectives The objective of this study is to investigate whether papers reporting research on Chinese transplant recipients comply with international professional standards aimed at excluding publication of research that: (1) involves any biological material from executed prisoners; (2) lacks Institutional Review Board (IRB) approval and (3) lacks consent of donors.Design Scoping review based on Arksey and O’Mallee’s methodological framework.Data sources Medline, Scopus and Embase were searched from January 2000 to April 2017.Eligibility criteria We included research papers published in peer-reviewed English-language journals reporting on outcomes of research involving recipients of transplanted hearts, livers or lungs in mainland China.Data extraction and synthesis Data were extracted by individual authors working independently following training and benchmarking. …”
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4935
Multi-Omics and Network-Based Drug Repurposing for Septic Cardiomyopathy
Published 2025-01-01“…Methods: We generated a mouse model of SCM induced by lipopolysaccharide (LPS) and then obtained comprehensive metabolic and genetic data from SCM mouse hearts using ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) and RNA sequencing (RNA-seq). …”
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4936
Experimental study of partially oxidized sodium alginate gel combined with myogenic stem cells to improve cardiac function in aged rats with myocardial infarction
Published 2025-01-01“…[Methods] The models of myocardial infarction in aged rats were established by ligating the coronary arteries and divided randomly into the group of saline control group, sodium alginate group, myogenic stem cells group and sodium alginate combined with myogenic stem cells group(joint group), each had 30 rats.The same amount of corresponding material was injected into the myocardial infarction area of rats in each group respectively.The cardiac structure and function of the rats were evaluated by echocardiography 8 weeks after the operation, and then the rats were executed.The hearts were removed to observe the differences in ventricular remodeling by histological analysis and the angiogenesis and collagen secretion of the ventricular slices were further analyzed. …”
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4937
Complementary Embryonic and Adult Cell Populations Enhance Myocardial Repair in Rat Myocardial Injury Model
Published 2019-01-01“…Isl-1+ cells were isolated from embryonic day 12.5 (E12.5) rat hearts and expanded in vitro. Thy-1+/CD90+ cells were isolated from the bone marrow of adult Sprague-Dawley rats by immunomagnetic cell sorting. …”
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4938
Preface
Published 2018-12-01“…More than 10 years have passed since he is not with us, but we still keep bright memories and warm feelings towards him in our hearts.…”
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4939
The Life Mission Theory III. Theory of Talent
Published 2003-01-01“…Full expression of self happens when a person, in full acceptance of body and life, with whole-hearted intension, uses all his personal powers to realize his core talent and all associated talents, to contribute to his beloved and to the world. …”
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4940
Osobowość ekologiczna płci - badania ankietowe
Published 2008-12-01“…It is women who with their hearts read and introduce into life philosophical life and written theological works whose authors are men. …”
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