Cross-Sectional Relationship between Carotid-Femoral Pulse Wave Velocity and Biomarkers in Vascular-Related Diseases by Jinbo Liu, Kuanting Wang, Huan Liu, Hongwei Zhao, Wei Huang, Na Zhao, Lihong Li, Hongyu Wang

“…There were 377 patients with hypertension, 231 with coronary heart disease, 154 with diabetes mellitus, and 186 healthy subjects. …”
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Lifestyle Interventions Targeting Body Weight Changes during the Menopause Transition: A Systematic Review by Janet Jull, Dawn Stacey, Sarah Beach, Alex Dumas, Irene Strychar, Lee-Anne Ufholz, Stephanie Prince, Joseph Abdulnour, Denis Prud’homme

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Regular exercise in adolescents with ACE gene polymorphism helps preventing cardiovascular risk factors by Nivaldo de Jesus Silva Soares Junior, Carlan Senna, Carlos Alberto Alves Dias-Filho, Bruno Rodrigues, Maria Claudia Irigoyen, Danielle da Silva Dias, Vinícius Santos Mendes, Carlos José Moraes Dias, Sally Cristina Moutinho Monteiro, Cristiano Teixeira Mostarda

“…Afterward, an electrocardiogram was performed to analyze heart rate variability and oral mucosal cells were collected for the genotypic of angiotensin-converting enzyme. …”
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The synergistic role of gut microbiota and RNA in metabolic diseases: mechanisms and therapeutic insights by Zhuo Huang, Zhuo Huang, Qinyan Yao, Qinyan Yao, Shuang Ma, Shuang Ma, Jinjie Zhou, Jinjie Zhou, Xiaoxuan Wang, Xiaoxuan Wang, Qingguo Meng, Qingguo Meng, Yaxin Liu, Yaxin Liu, Zihan Yu, Zihan Yu, Xin Chen, Xin Chen

“…Dysbiosis of the gut microbiota has been linked to metabolic disorders such as type 2 diabetes, obesity, metabolic-associated fatty liver disease (MAFLD) and metabolic heart disease. Microbial metabolites, including short-chain fatty acids (SCFAs), modulate RNA expression, influencing lipid metabolism, glucose regulation, and inflammatory responses. …”
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Terlipressin at esophageal varicose bleeding at liver cirrhosis with portal hypertension syndrome by B. N. Kotiv, I. I. Dzidzava, D. P. Kashkin, A. V. Smorodsky, A. V. Slobodyanik, S. A. Soldatov, M. V. Koldin

“…Though the level of mean blood pressure and heart rate decreased, only reduction of cardiac output in the main group significantly differed from reference values.Conclusion. …”
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Beyond traditional metrics: evaluating the triglyceride-total cholesterol-body weight index (TCBI) in cardiovascular risk assessment by Mohsen Rezaee, Farzam Kamrani, Mobina Imannezhad, Hamed Hashemi Shahri, Waleed Khaled Saihood, Alireza Rezvani, Parsa Mearaji Far, Hanie Mahaki, Habibollah Esmaily, Mohsen Moohebati, Mohammad Shariati, Majid Ghayour-Mobarhan, Susan Darroudi

“…Methods A prospective cohort study was conducted on Mashhad stroke and heart atherosclerotic disorder (MASHAD) study data, involving 9704 healthy participants. …”
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Does an increase in physiological indexes predict better cognitive performance: the PhyCog randomised cross-over protocol in type 2 diabetes by Frederic Dutheil, Guillaume T Vallet, Igor Tauveron, Julien S Baker, Valentin Magnon, Jordan Mille, Valentin Brusseau, Laetitia Silvert, Marie Izaute

“…Physiological testing will involve allostatic load such as heart rate variability, microcirculation, cortisol and dehydroepiandrosterone sulfate levels. …”
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Characteristics and Surgical Results of Patients with Hypertrophic Obstructive Cardiomyopathy without Intrinsic Mitral Valve Diseases Undergoing Mitral Subvalvular Procedures durin... by Qiang Ji, YuLin Wang, Ye Yang, LiMin Xia, WenJun Ding, Kai Song, ChunSheng Wang

“…Comparatively, the combined group was younger (52.9 ± 11.2 years vs. 56.8 ± 11.8 years, p=0.045) and had a better New York Heart Association (NYHA) class (p=0.034) and less septal hypertrophy (16.4 ± 2.3 mm vs. 18.5 ± 3.2 mm, p<0.001). …”
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Biomedical and candidate SN P markers of chronopathologies can significantly change affinity of ТАТА -binding protein for human gene promoters by D. A. Rasskazov, N. L. Podkolodnyy, O. A. Podkolodnaya, N. N. Podkolodnaya, V. V. Suslov, L. K. Savinkova, P. M. Ponomarenko, M. P. Ponomarenko

“…In the [–70; –20] region of promoters of 14 human genes (location of proven binding sites of ТВР), we found 32 known and candidate SNP markers of circadian- rhythm disturbances, including rs17231520 and rs569033466 (both: risk of chronopathologies in liver); rs35036378 (behavioral chronoaberrations); rs549858786 (rheumatoid arthritis with a chronoaberration of IL1B expression); rs563207167, rs11557611, and rs5505 (all three: chronopathologies of the tumor – host balance, blood pressure, and the reproductive system); rs1143627 (bipolar disorder with circadian dependence of diagnosis and treatment); rs16887226 and rs544850971 (both: lowered resistance to endotoxins because of the imbalance between the circadian and immune systems); rs367732974 and rs549591993 (both: circadian dependence of heart attacks); rs563763767 (circadian dependence of myocardial infarction); rs2276109 and rs572527200 (both: circadian dependence of asthma attacks); rs34223104, rs563558831, and rs10168 (circadian optima of treatment with methotrexate and cyclophosphamide); and rs397509430, rs33980857,rs34598529, rs33931746, rs33981098, rs34500389, rs63750953, rs281864525, rs35518301, and rs34166473 (all: neurosensory hearing loss and restless legs syndrome). …”
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Diagnostic features, management and prognosis of type 2 myocardial infarction compared to type 1 myocardial infarction: a systematic review and meta-analysis by Kyle White, Ian Scott, Mansey Kinarivala

“…Compared with T1MI, patients with T2MI were: more likely to have pre-existing chronic kidney disease (OR 1.87; 95% CI 1.53 to 2.28) and chronic heart failure (OR 2.35; 95% CI 1.82 to 3.03), less likely to present with typical cardiac symptoms of chest pain (OR 0.19; 95% CI 0.13 to 0.26) and more likely to present with dyspnoea (OR 2.64; 95% CI 1.86 to 3.74); more likely to demonstrate non-specific ST-T wave changes on ECG (OR 2.62; 95% CI 1.81 to 3.79) and less likely to show ST elevation (OR 0.22; 95% CI 0.17 to 0.28); less likely to undergo coronary angiography (OR 0.09; 95% CI 0.06 to 0.12) and percutaneous coronary intervention (OR 0.06; 95% CI 0.04 to 0.10) or receive cardioprotective medications, such as statins (OR 0.25; 95% CI 0.16 to 0.38) and beta-blockers (OR 0.45; 95% CI 0.33 to 0.63). …”
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Hyperuricemia is a Risk Factor for One-Year Overall Survival in Elderly Female Patients with Acute Coronary Syndrome by Shi Tai, Xuping Li, Zhaowei Zhu, Liang Tang, Hui Yang, Liyao Fu, Xinqun Hu, Zhenfei Fang, Shenghua Zhou

“…Prevalence of hypertension (80.5% vs. 72.6%, P=0.020), atrial fibrillation (16.2% vs. 9.5%, P=0.008), and severe heart failure (61.0% vs. 44.2%, P<0.001) were higher in patients with hyperuricemia than in patients with normal sUA. …”
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Association of extreme heat events with sleep and cardiovascular health: a scoping review by Nathan Ashe, Sarah Wozniak, Malcolm Conner, Rayan Ahmed, Olivia Keenan, Michelle R. Demetres, Nour Makarem, Parisa Tehranifar, Rajalakshmi Nandakumar, Arnab K. Ghosh

“…Cardiovascular (CV) measures described included blood pressure (BP), heart rate (HR), and HR variability (no CVD outcomes were described), and objective and subjective measurements of sleep health outcomes included sleep duration, calmness, ease of falling asleep, ease of awakening, freshness after awakening, and sleep satisfaction. …”
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Doxycycline and Benznidazole Reduce the Profile of Th1, Th2, and Th17 Chemokines and Chemokine Receptors in Cardiac Tissue from Chronic Trypanosoma cruzi-Infected Dogs by Guilherme de Paula Costa, Laís Roquete Lopes, Maria Cláudia da Silva, Aline Luciano Horta, Washington Martins Pontes, Cristiane M. Milanezi, Paulo Marcos da Mata Guedes, Wanderson Geraldo de Lima, Richard Schulz, João Santana da Silva, Andre Talvani

“…T. cruzi infection increases CCL1, CCL2, CCL4, CCL5, CCL17, CXCL10, and CCR5 expression in the heart. Dox, Bz, or Dox + Bz treatments cause a reversal of CK and CKR and reduce the expression of CCL20, IL-17, CCR6, and CXCR3. …”
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Forecasting stroke and stroke-driven dementia in a rapidly ageing population: a model-based analysis of alternative projection scenarios for Ireland by Anne Hickey, Eithne Sexton, Frances Horgan, Kathleen E Bennett, Ronan Collins, Martin O'Flaherty, Suzanne Timmons, Chris Macey, David J. Williams

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Does diabetes modify the triglyceride–glucose index associated with cardiovascular events and mortality? A meta-analysis of 50 cohorts involving 7,239,790 participants by Jun Zhang, Qiye Zhan, Zhihao Deng, Ling Lin, Zhaolan Feng, Huabin He, Deju Zhang, Huilei Zhao, Xiang Gu, Xiaoping Yin, Peng Yu, Xiao Liu

“…However, the associations between the TyG index and ischemic heart disease (IHD) (HR: 2.20 vs. 1.57, P = 0.03) as well as all-cause mortality (HR: 1.94 vs. 1.24, P = 0.01) were stronger in DM patients than in non-DM patients. …”
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Blood absolute lymphocyte count and trajectory are important in understanding severe COVID-19 by Catharine I. Paules, Jacqueline A. Nordwall, Kathryn Shaw-Saliba, Judith A. Aberg, Edward M. Gardner, Anna L. Goodman, N. Kumarasamy, Shikha Vasudeva, David M. Vock, Crystal M. North, Jens Lundgren, Neil R. Aggarwal, for the STRIVE Network and TICO Trial Study Group

“…Persistent and new lymphopenia were associated with older age, male sex; prior immunosuppression, heart failure, aspirin use, and normal body mass index; biomarkers of organ damage (renal and lung), and ineffective immune response (elevated IL-6 and viral nucleocapsid antigen levels). …”
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Prolonged Cardiopulmonary Bypass Time-Induced Endothelial Dysfunction via Glypican-1 Shedding, Inflammation, and Matrix Metalloproteinase 9 in Patients Undergoing Cardiac Surgery by Shiyi Li, Katherine V. Nordick, Iván Murrieta-Álvarez, Randall P. Kirby, Rishav Bhattacharya, Ismael Garcia, Camila Hochman-Mendez, Todd K. Rosengart, Kenneth K. Liao, Nandan K. Mondal

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Recurrent Thrombotic Events after Discontinuation of Vitamin K Antagonist Treatment for Splanchnic Vein Thrombosis: A Multicenter Retrospective Cohort Study by Nicoletta Riva, Walter Ageno, Daniela Poli, Sophie Testa, Serena Rupoli, Rita Santoro, Teresa Lerede, Antonietta Piana, Monica Carpenedo, Alberto Nicolini, Piera Maria Ferrini, Giuliana Martini, Catello Mangione, Laura Contino, Carlo Bonfanti, Paolo Gresele, Alberto Tosetto

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Preoperative carcinoembryonic antigen to lymphocyte ratio serves as a prognostic predictor in elderly patients with colorectal cancer: a multicentre retrospective study by Lei Jiang, Ning Tan, Xiaonan Zhang, Jiayi Jiang, Xinyi Li, Gang Deng, Tao Liang, Haohan Ma, Weiping Deng, Lichang Guan, Kaijun Zhang, Xujie Cai, Lishu Xu

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Interrelation between hypoxic liver injury and Killip classification in ST-segment elevation myocardial infarction patients by Seong Huan Choi, Ji-Hun Jang, Dae-Young Kim, Young Ju Suh, Yong-Soo Baek, Sung-Hee Shin, Seong-Ill Woo, Dae-Hyeok Kim, Jeonggeun Moon, Jon Suh, WoongChol Kang, Sang-Don Park, Sung Woo Kwon

“…Left ventricular ejection fraction (LVEF) was below 45% in symptomatic, overt heart failure patients (Killip class II, III, and IV). …”
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