Dose-Dense Epirubicin and Cyclophosphamide Followed by Docetaxel as Adjuvant Chemotherapy in Node-Positive Breast Cancer by Hamid Reza Mirzaei, Parisa Sabet Rasekh, Fatemeh Nasrollahi, Parto Sabet Rasekh, Zahra Akbari Tirabad, Hamid Reza Moein, Taban Ghaffari Pour, Parastoo Hajian

“…There were two toxicity-related deaths, one patient due to grade 4 febrile neutropenia and the other due to congestive heart failure. Grade 3/4 neutropenia and febrile neutropenia were 13.8% and 5.1%. …”
Get full text

Serum sodium to chloride ratio and mortality on continuous ambulatory peritoneal dialysis: a multicenter retrospective study by Jiayin You, Sijie Gu, Ning Su, Xiaoran Feng, Fenfen Peng, Qingdong Xu, Xiaojiang Zhan, Yueqiang Wen, Xiaoyang Wang, Na Tian, Xianfeng Wu, Niansong Wang

“…Abstract An imbalance in the serum sodium to chloride ratio (Na/Cl) was linked to higher mortality among heart failure patients. Nonetheless, the prognostic significance of Na/Cl in individuals undergoing peritoneal dialysis (PD) remains unexplored. …”
Get full text

Effect of a perinatal care quality improvement package on patient satisfaction: a secondary outcome analysis of a cluster-randomised controlled trial by Ashish KC, Anna Bergstrom, Mats Målqvist, Dipak Chaulagain, Olivia Brunell

“…Participating hospitals were randomised by size into four different wedges.Setting 12 secondary-level public hospitals in Nepal.Participants Women who gave birth in the hospitals at a gestational age of ≥22 weeks, with fetal heart sound at admission. Adverse outcomes were excluded. …”
Get full text

Risk factors associated with the failure of local methotrexate combined with minimally invasive surgery for late cesarean scar pregnancy by Xiao-Tong Cheng, Yan-Song Liu, Dan-Yang Song, Xiao-Cui Nie, Yu-Shi Xiang, Ju-Min Niu

“…In the univariate analysis, several potential risk factors associated with the initial combined treatment failure were identified, including baseline serum β-human chorionic gonadotropin (β-hCG) levels, type of CSP, time interval between MTX and surgery, and positive fetal heart activity before surgery. Subsequent binary logistic regression analysis revealed the following independent risk factors linked to the failure of the initial combined treatment: baseline serum β-hCG levels exceeding 94,000 IU/L [odds ratio (OR) 3.060, 95% confidence interval (CI) 1.387–6.749, P = 0.006], type III CSP (OR 3.574, 95% CI 1.147–11.135, P = 0.028), a time interval greater than seven days between MTX and surgery (OR 3.847, 95% CI 1.725–8.581, P = 0.001), and the presence of a fetal heartbeat before surgery (OR 4.405, 95% CI 1.014–19.128, P = 0.048). …”
Get full text

Unveiling the molecular and cellular links between obstructive sleep apnea-hypopnea syndrome and vascular aging by Wei Liu, Le Zhang, Wenhui Liao, Huiguo Liu, Wukaiyang Liang, Jinhua Yan, Yi Huang, Tao Jiang, Qian Wang, Cuntai Zhang, Peifang Wei

“…A substantial proportion of OSAHS patients, estimated to be between 40% and 80%, have comorbidities such as hypertension, heart failure, coronary artery disease, pulmonary hypertension, atrial fibrillation, aneurysm, and stroke, all of which are closely associated with VA. …”
Get full text

The in ovo screening of 27 single essential oils showed selective effects on hatchability, performance and gene expression relevant to gut functions in broilers at hatch by Asad A. Khaskheli, Shahram Niknafs, Mila M.Y. Meijer, Xinle Tan, Peter R. Ferket, Eugeni Roura

“…Hatchability, body weight and organ weights (residual yolk, gizzard-proventriculus, intestines, liver, and heart) were measured at hatch. Five essential oils eugenol, clove, tea tree, lemongrass, and thyme, significantly (P < 0.05) reduced hatchability (66.67 %, 58.33, 83.30 and 83.30 %) compared to the saline (96.80 %), were discarded from the rest of the study. …”
Get full text

Prevalence and Associated Factors of Hypertension among Women in Southern Ghana: Evidence from 2014 GDHS by Cyprian Issahaku Dorgbetor, Kwamena Sekyi Dickson, Edward Kwabena Ameyaw, Kenneth Setorwu Adde

“…Hypertension, coupled with prehypertension and other hazards such as high blood pressure, is responsible for 8·5 million deaths from stroke, ischaemic heart disease, other vascular diseases, and renal disease worldwide. …”
Get full text

Traditional Cardiovascular Risk Factors Associated with Diagonal Earlobe Crease (Frank Sign) in Mexican Adults: Aging, Obesity, Arterial Hypertension, and Being Male Are the Most I... by Rogelio Molina-Gallardo, Nomely S. Aurelien-Cabezas, Daniel Tiburcio-Jimenez, Jorge E. Plata-Florenzano, Jose Guzman-Esquivel, Iram P. Rodriguez-Sanchez, Margarita L. Martinez-Fierro, Roque Molina-Osorio, Adrian A. De-la-Madrid-Cernas, Jorge Armando Barriguete-Melendez, Ivan Delgado-Enciso

“…Cardiovascular risk factors such as obesity, type 2 diabetes, hypertension, smoking, and dyslipidemia enfold heart disease morbimortality. Diagonal earlobe crease has been proposed as a prognostic marker of extension and severity of illness in patients with acute coronary syndrome. …”
Get full text

Accuracy of Large Language Models for Infective Endocarditis Prophylaxis in Dental Procedures by Paak Rewthamrongsris, Jirayu Burapacheep, Vorapat Trachoo, Thantrira Porntaveetus

“…Methods: Twenty-eight true/false questions based on the 2021 American Heart Association (AHA) guidelines for IE were posed to 7 popular LLMs. …”
Get full text

Characteristics, Mortality, and Clinical Outcomes of Hospitalized Patients with COVID-19 and Diabetes: A Reference Single-Center Cohort Study from Poland by Michał Kania, Konrad Mazur, Michał Terlecki, Bartłomiej Matejko, Jerzy Hohendorff, Zlata Chaykivska, Mateusz Fiema, Marianna Kopka, Małgorzata Kostrzycka, Magdalena Wilk, Tomasz Klupa, Przemysław Witek, Barbara Katra, Marek Klocek, Marek Rajzer, Maciej T. Malecki

“…In a multivariate logistic regression, factors associated with a higher risk of death were age >65 years, glycaemia >10 mmol/L, CRP and D-dimer level, prehospital insulin and loop diuretic use, presence of heart failure, and chronic kidney disease. Factors contributing to lower mortality were in-hospital use of statin, thiazide diuretic, and calcium channel blocker. …”
Get full text

Prevalence of cardiovascular symptoms in post-acute COVID-19 syndrome: a meta-analysis by Li-wei Huang, Hua-min Li, Bei He, Xiao-bo Wang, Qi-zhi Zhang, Wen-xing Peng

“…Abstract Background Since its emergence in 2019, COVID-19 has continued to pose significant threats to both the physical and mental health of the global population, as well as to healthcare systems worldwide (Raman et al., Eur Heart J 43:1157–1172, 2022). Emerging evidence indicates that COVID-19 may lead to post-acute COVID-19 syndrome (PACS) with cardiovascular implications, potentially driven by factors such as ACE2 interaction with viruses, systemic inflammation, and endothelial dysfunction. …”
Get full text

Prevalence of complications and comorbidities associated with obesity: a health insurance claims analysis by Jay P. Bae, David R. Nelson, Kristina S. Boye, Kieren J. Mather

“…Disorders such as obstructive sleep apnea, osteoarthritis, type 2 diabetes, metabolic dysfunction-associated steatotic liver disease, coronary heart diseases (CHD), and chronic kidney diseases also exhibited substantial burden among those with obesity. …”
Get full text

The experience of bodily image for patients with left ventricular assist device by Irena Milaniak, Emilia Witkowska, Marta Cebula, Paulina Tomsia, Grzegorz Wasilewski, Izabela Górkiewicz-Kot, Sylwia Wiśniowska-Śmiałek, Michał Kaleta, Karol Wierzbicki, Karol Wierzbicki

“…IntroductionMechanical Cardiac Support and Left Ventricular Assist Devices (LVAD) have been demonstrated to prolong Heart Failure patients' survival and improve their quality of life. …”
Get full text

ECG-LM: Understanding Electrocardiogram with a Large Language Model by Kai Yang, Massimo Hong, Jiahuan Zhang, Yizhen Luo, Suyuan Zhao, Ou Zhang, Xiaomao Yu, Jiawen Zhou, Liuqing Yang, Ping Zhang, Mu Qiao, Zaiqing Nie

“…Background: The electrocardiogram (ECG) is a valuable, noninvasive tool for monitoring heart-related conditions, providing critical insights. …”
Get full text

Clinical relevance of macromolecular complexes involving integrins, potassium and sodium ion channels and the sodium/proton antiporter in human breast cancer by Elena Lastraioli, Jessica Iorio, Francesco Piazza, Chiara Capitani, Michele Santillo, Claudia Duranti, Simonetta Bianchi, Icro Meattini, Scott P. Fraser, Mustafa B. A. Djamgoz, Andrea Becchetti, Annarosa Arcangeli

“…Results The expression of KCNH2 and SCN5A was significantly correlated in primary BCa as occurs in the heart, although with a broader distribution, forming a functional network which also included ITGB1 and SLC9A1. …”
Get full text

Association between life's essential 8 and Parkinson's disease: a case–control study by Jiaxin Fan, Yanfeng Wang, Xingzhi Guo, Shuai Cao, Shuqin Zhan, Rui Li

“…The LE8 metrics were calculated according to the American Heart Association criterion, and participants were divided into 3 groups using tertile range. …”
Get full text

Effect of Genetic Predisposition on Blood Lipid Traits Using Cumulative Risk Assessment in the Korean Population by Min Jin Go, Joo-Yeon Hwang, Dong-Joon Kim, Hye-Ja Lee, Han Byul Jang, Kyung-Hee Park, Jihyun Song, Jong-Young Lee

Get full text

Eight weeks of aerobic exercise, but not four, improves insulin sensitivity and cardiovascular performance in young women by Maha Sellami, Shamma Almuraikhy, Khaled Naja, Najeha Anwardeen, Hadaia Saleh Al-Amri, Mohammad Shoaib Prince, Amina Ali Aden, Alexander Doemling, Mohamed A. Elrayess

“…The aerobic intervention maintained an intensity of 40–70% of maximum heart rate (HRmax). 6-min-walk test (6MWT), handgrip strength tests, insulin, HOMA-IR, lipid profiles, and metabolic profiles were assessed pre- and post-intervention. …”
Get full text

Gait kinematics at trot before and after repeated ridden exercise tests in young Friesian stallions during a fatiguing 10-week training program by Esther W. Siegers, Jeanne I. M. Parmentier, Jeanne I. M. Parmentier, Marianne M. Sloet van Oldruitenborgh-Oosterbaan, Carolien C. B. M. Munsters, Filipe M. Serra Bragança

“…Earlier, this training program was demonstrated to induce overtraining.ObjectivesTo evaluate how this training program affects stallions’ trot locomotion variables in relation to fatigue.Study designProspective analytical study.Methods3 or 4 years-old (n = 16) Friesian stallions performed three ridden indoor standardized exercise tests (SETs) in week-1 (SET-I; n = 15), week-6 (SET-II; n = 11) and week-10 (SET-III; n = 4), measuring heart rate (bpm) and lactate concentration (LA, mmol/L). …”
Get full text

Diagnostic Management and Surgical Treatment of Isolated Tricuspid Regurgitation by Arthur Cicupira Rodrigues de Assis, Gustavo Andre Boeing Boros, Lea Maria Macruz Ferreira Demarchi, Thiago Luis Scudeler, Paulo Cury Rezende

“…The patient was discharged with no signs or symptoms of right heart failure. The histopathological examination showed significant and diffuse myxomatous degeneration of the leaflets. …”
Get full text