Prevalence and Economic Impact of Acute Respiratory Failure in the Prehospital Emergency Medical Service of the Madrid Community: Retrospective Cohort Study by Ana María Cintora-Sanz, Cristina Horrillo-García, Víctor Quesada-Cubo, Ana María Pérez-Alonso, Alicia Gutiérrez-Misis

“… Abstract BackgroundChronic obstructive pulmonary disease (COPD), congestive heart failure (CHF), and acute pulmonary edema (APE) are serious illnesses that often require acute care from prehospital emergency medical services (EMSs). …”
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Development and validation of a prediction model for acute kidney injury following cardiac valve surgery by Xiaotong Jia, Jun Ma, Zeyou Qi, Dongni Zhang, Junwei Gao

“…Based on multivariate analysis, advanced age (OR: 1.855; p = 0.011), preoperative hypertension (OR: 1.91; p = 0.017), coronary heart disease (OR: 6.773; p < 0.001), preoperative albumin (OR: 0.924; p = 0.015), D-Dimer (OR: 1.001; p = 0.038), plasma creatinine (OR: 1.025; p = 0.001), cardiopulmonary bypass (CPB) duration (OR: 1.011; p = 0.001), repeat CPB (OR: 6.195; p = 0.010), intraoperative red blood cell transfusion (OR: 2.560; p < 0.001), urine volume (OR: 0.406 p < 0.001) and vasoactive–inotropic score (OR: 1.135; p = 0.009) were independent risk factors for AKI. …”
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The Chromosome 9p21 CVD- and T2D-Associated Regions in a Norwegian Population (The HUNT2 Survey) by Øyvind Helgeland, Jens K. Hertel, Anders Molven, Helge Ræder, Carl G. P. Platou, Kristian Midthjell, Kristian Hveem, Ottar Nygård, Pål R. Njølstad, Stefan Johansson

“…By a population based cross-sectional case-control design, we genotyped 18 SNPs upstream of CDKN2B tagging 138 kb in and around two LD-blocks associated with CVD and T2D and investigated associations with T2D, angina pectoris (AP), myocardial infarction (MI), coronary heart disease (CHD; AP or AMI), and stroke using 5,564 subjects from HUNT2. …”
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Interactions of ST-elevation myocardial infarction, age, and sex and the risk of major adverse cardiovascular events among Chinese adults: a secondary analysis of a single-centre p... by Lin Zhou, Wei Yuan, Cuiping Wang, Yi Liang, Peijing Liu

“…A total of 843 adults were included in the analysis.Primary and secondary outcome measures MACE was defined as any occurrence of cardiovascular mortality, MI recurrence, cardiogenic shock or heart failure. The relative excess risk due to interaction (RERI), attributable proportion (AP) and the synergy index were computed to quantify the interactions. …”
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Utility of Circadian Variability Patterns in Differentiating Origins of Premature Ventricular Complexes by Mu Chen, Qunshan Wang, Jian Sun, Peng-Pai Zhang, Wei Li, Rui Zhang, Bin-Feng Mo, Tai-Zhong Chen, Juyi Wan, Dong-Zhu Xu, Kazutaka Aonuma, Yi-Gang Li

“…PVC circadian patterns were classified as fast-heart rate- (HR-) dependent (F-PVC), slow-HR-dependent (S-PVC), or HR-independent (I-PVC). …”
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Circulating endothelial progenitor cells and inflammatory markers in type 1 diabetes after an acute session of aerobic exercise by Patrícia Martins Bock, Raíssa Borges Monteiro, Clara Krummenauer Maraschin, Ana Paula Alegretti, Mariela Granero Farias, Fabiane Spagnol, Patricia Luciana da Costa Lopez, Lucas Porto Santos, Lucas Helal, Ruy Silveira Moraes, Daniel Umpierre, Beatriz D. Schaan

“…Subjects and methods: In total, 15 adult men with T1DM and 15 healthy individuals underwent a 30-minute aerobic exercise session on a cycle ergometer at 60% of the peak heart rate. The EPC count (CD45dim/CD34+/KDR+), tumor necrosis factor-alpha (TNF-α) and interleukin 6 (IL-6) levels were measured before and 60 minutes after the session. …”
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Cardioneuroablation for reflex syncope or functional bradyarrhytmias: new insight from a single center experience by Noemi Valenti, Antonio Di Monaco, Imma Romanazzi, Nicola Vitulano, Federica Troisi, Federico Quadrini, Antonio Vitullo, Luca Sgarra, Rosa Caruso, Vincenzo Anzelmo, Pietro Guida, Natale Daniele Brunetti, Massimo Grimaldi

“…As regards the acute results, we highlighted an increase in sinus heart rate (12 ± 15 bpm, p = 0.001), a shortening of the PQ interval (−18 ± 18 msec, p < 0.001), a reduction of the correct sinus node recovery times (cSNRT) (−142 ± 204 msec, p = 0.114), a shortening of the AH interval (−31 ± 26 msec, p = 0.008), a reduction of the effective refractory period of the atrio-ventricular node (−156; interquartile range from −30 to −160 msec, p = 0.042) and an increase in the Wencheback point (27 ± 20 bpm, p < 0.001). …”
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Effects of the New Aldose Reductase Inhibitor Benzofuroxane Derivative BF-5m on High Glucose Induced Prolongation of Cardiac QT Interval and Increase of Coronary Perfusion Pressure by C. Di Filippo, B. Ferraro, R. Maisto, M. C. Trotta, N. Di Carluccio, S. Sartini, C. La Motta, F. Ferraraccio, F. Rossi, M. D’Amico

“…BF-5m also increased the expression levels of sirtuin 1, MnSOD, eNOS, and FOXO-1, into the heart. The beneficial actions of BF-5m were partly abolished by the pretreatment of the rats with the inhibitor of the sirtuin 1 activity EX527 (10 mg/kg/day/7 days i.p.) prior to perfusion of the hearts with high glucose + BF-5m (0.1 μM). …”
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Dietary omega-3 fatty acids affect the growth performance of broiler chickens reared at high stocking density by Shahgol Rahbari, Abdolreza Salehi, Seyed Davood Sharifi, Shirin Honarbakhsh

“…The results showed that body weight gain (BWG) and FCR was improved (P < 0.05) in high SD broilers during the grower phase (days 15–24).The BWG of broilers under high SD and dietary omega-3 fatty acids was higher than others (P < 0.05) during the finisher phase (d 25-40). Carcass and total heart weight were higher in birds fed diets containing omega-3 fatty acids under high SD than in birds fed a diet low in omega-3 fatty acids at low or high SD (P < 0.05). …”
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Allium cepa L. as a natural antioxidant: Its efficacy in combating heat stress-induced physiological alterations by Ayobami O. Sobanke, Afusat Aiyeola, Frances I. Okwuonu, Wuraola S. Nnaemeka, Jeremiah C. Ndubuisi, Franklin I. Udeoji, Jane N. Adiele

“…Hematological parameters, inflammatory markers, and lipid profiles were analyzed using blood samples obtained through heart puncture.The findings demonstrated that HS significantly lowered levels of hemoglobin (HB), red blood cell (RBC) counts, and antioxidant enzyme activity. …”
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How to Reliably Measure Stroke Volume Index in Pulmonary Arterial Hypertension: A Comparison of Thermodilution, Direct and Indirect Fick, and Cardiac MRI by Andrea Baccelli, Deepa Gopalan, Rachel J. Davies, Gulammehdi Haji, Wendy Gin-Sing, Luke S. Howard, Francesco Lo Giudice

“…We enrolled 103 PAH patients undergoing a diagnostic or follow-up right heart catheterization at our centre (mean age 56 years, 56% female). …”
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Surveillance of Pediatric Cardiac Surgical Outcome Using Risk Stratifications at a Tertiary Care Center in Thailand by Chodchanok Vijarnsorn, Duangmanee Laohaprasitiporn, Kritvikrom Durongpisitkul, Prakul Chantong, Jarupim Soongswang, Paweena Cheungsomprasong, Apichart Nana, Somchai Sriyoschati, Thawon Subtaweesin, Punnarerk Thongcharoen, Ungkab Prakanrattana, Jiraporn Krobprachya, Julaporn Pooliam

“…The risk adjustment for congenital heart surgery (RACHS-1) method, the Aristotle basic complexity score (ABC score), and the Society of Thoracic Surgeons and the European Association for Cardiothoracic Surgery Mortality score (STS-EACTS score) were used as measures. …”
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Systemic Immune-inflammation Index in Evaluation of Inflammation in Rheumatoid Arthritis Patients by Amela DERVISEVIC, Almir FAJKIC, Elmedina JAHIC, Lejla DERVISEVIC, Zurifa AJANOVIC, Enisa ADEMOVIC, Asija ZACIRAGIC

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Microplastic polymers in shellfish and fish in the coastal area by S. Basri K., A. Daud, A.B. Birawida, M. Maming, H.J. Mukono, D.S. Arsyad

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Protocol for the systematic review of age and sex in preclinical models of age-correlated diseases [version 2; peer review: 2 approved] by Céline Heinl, Ines Schadock, Maximilian Wurm, Paul Lucas Wildner, Daniel Butzke, Bettina Bert, Alexandra Bannach-Brown, Matthias Steinfath, Kai Diederich

“…We compare the results with the age and sex of patients in clinical trials focusing on Alzheimer's disease, stroke, type 2 diabetes mellitus, ischemic heart disease, and chronic obstructive pulmonary disease. …”
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Lymphoadenopathies caused by Bartonella henselae by V.S. Zhukovskiy, O.V. Prokopiv, I.R. Trutyak, M.V. Pankiv

“…Bartonella henselae is the causative agent of cat scratch disease, the main manifestation of which is lymphadenopathy, but it can manifest as bacillary angiomatosis, injury to internal organs, joints, eyes, heart, kidneys. This disease is often encountered in the practical work of doctors, especially with an atypical form of the course, which occurs in 20% of adult patients. …”
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The First Harmonic of Radial Pulse as an Early Predictor of Silent Coronary Artery Disease and Adverse Cardiac Events in Type 2 Diabetic Patients by Chi-Wei Chang, Kuo-meng Liao, Yi-Ting Chang, Sheng-Hung Wang, Ying-chun Chen, Gin-Chung Wang

“…By comparing the data of patients with C1 smaller than the first quartile and the patients with C1 greater than the third quartile, the hazard ratios were listed as follows: ACE (hazard ratio, 2.29; 95% CI, 1.55–3.37), heart failure (hazard ratio, 2.22; 95% CI, 1.21–4.09), myocardial infarction (hazard ratio, 2.44; 95% CI, 1.51–3.93), left ventricular dysfunction (Hazard ratio, 2.01; 95% CI, 0.86–4.70), and new symptoms and signs for coronary artery disease (hazard ratio, 2.03; 95% CI, 1.45–2.84). …”
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The Relationship between Left Ventricular Diastolic Function Parameters and Coronary Artery Disease Severity by Khadije Mohammadi, Mohammad Masoomi, Mahsa Akrami, Shirin Habibi Khorasani, Mina Moridi, Sara Saidi

“…This study aimed to determine the relationship between left ventricular diastolic function and the severity of CAD.Methods: This cross-sectional study included 63 patients with Ischemic heart disease (IHD) or those suspected of having IHD, who underwent angiography. …”
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Intrapericardial injection of hydrogels with ASC and their secretome to treat dilated cardiomyopathies by Tácia Tavares Aquinas Liguori, Gabriel Romero Liguori, Viktor Sinkunas, Cristiano Jesus Correia, Raphael dos Santos Coutinho e Silva, Fernando Luiz Zanoni, Vera Demarchi Aiello, Martin Conrad Harmsen, Luiz Felipe Pinho Moreira

“…Abstract Doxorubicin-induced cardiomyopathy (DOX-IC) is a significant and common complication in patients undergoing chemotherapy, leading to cardiac remodeling and reduced heart function. We hypothesized that the intrapericardial injection of hydrogels derived from the cardiac decellularized extracellular matrix (dECM) loaded with adipose tissue-derived stromal cells (ASC) and their secretome dampens or reverses the progression of DOX-IC. …”
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Diagnostics and treatment of cardiac achalasia and cardiospasm: guidelines of the Russian gastroenterological association by V. T. Ivashkin, A. S. Trukhmanov, E. A. Godzhello, I. V. Mayev, Yu. V. Evsyutina, T. L. Lapina, O. A. Storonova

“…Differential diagnosis is carried out with cardioesophageal cancer, peptic stricture, esophageal webs and rings, neurogenic anorexia and coronary heart disease in the cases with chest pain. Barium meal study reveals dilation and deformity of the esophagus, coneshaped narrowing in the lower esophageal sphincter area, retention of barium contrast in the esophagus, absence of stomach gas bubble. …”
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