Pregnancy in Sickle Cell Disease Is a Very High-Risk Situation: An Observational Study by Narcisse Elenga, Aurélie Adeline, John Balcaen, Tania Vaz, Mélanie Calvez, Anne Terraz, Laetitia Accrombessi, Gabriel Carles

“…We also noted that the main maternofetal complications of pregnancies were anemia (36.5%), infection (31.7%), vasoocclusive crisis (20.6%), preeclampsia (17.5%), premature birth (11.1%), intrauterine growth retardation (15.9%), abnormal fetal heart rate (14.3%), and intrauterine fetal death (4.8%). …”
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Higher systemic immune-inflammation index is associated with increased risk of Parkinson’s disease in adults: a nationwide population-based study by Jiayu Zhao, Zhipeng Wu, Zhipeng Wu, Fengyin Cai, Xuejv Yu, Zhenyu Song

“…Subgroup analysis showed that this association was more significant in women, younger than 60 years old, non-smokers, alcohol drinkers, non-obese, and without a history of stroke, diabetes, or coronary heart disease. In addition, there was a positive dose-response relationship between SII and PD, and SII had an acceptable diagnostic value for PD (AUC = 0.72).ConclusionSII is positively correlated with the prevalence of PD in the adult population, and SII can help differentiate between PD and non-PD cases.…”
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Suggestive Diagnostic Process in a Case of Multiple Myeloma with Gastrointestinal Immunoglobulin Light-Chain Amyloidosis Accompanied by Protein-Losing Enteropathy by Katsuya Endo, Takehito Ito, Jun Nomura, Keigo Murakami, Shiho Kondo, Tomonori Satoh, Daisuke Fukushi, Yuki Yoshino, Yoshiteru Sasaki, Atsuko Takasu, Takayuki Kogure, Morihisa Hirota, Takayoshi Meguro, Kazuhiro Murakami, Junichi Kameoka, Kennichi Satoh

“…Multiple myeloma is known to cause immunoglobulin light-chain (AL) amyloidosis, which frequently involves the kidney and heart. Bone pain or fractures caused by osteolytic lesions and physical disorders related to renal or cardiac AL amyloidosis are major initial symptoms in multiple myeloma. …”
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Effect of auriculotherapy on anxiety-fatigue and sleep disturbances in cancer patients: A scoping review by Silmara de Oliveira Silva, Vinicius dos Santos Lemos Pereira, Mariane Elivânia Silva, Jucielly Ferreira da Fonseca, Maria Carolina Batista da Silva, Roberta Paolli de Paiva Oliveira Arruda Camara, Rodrigo Assis Neves Dantas, Daniele Vieira Dantas

“…The primary auricular points used were shenmen, followed by heart, subcortex, kidney, and sympathetic. The duration of the protocols ranged from three to eight weeks. …”
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Down syndrome and outcomes in critically ill pediatric patients by José Tantaleán Da Fieno, Rosa León Paredes, Patricia Palomo Luck, Carlos Del Águila Villar, Emiliana Rizo Patrón

“…Children with DS were younger and had a higher prevalence of comorbidities, congenital heart disease, and underweight. Both crude bivariate and multivariate analyses demonstrated that children with DS had higher mortality rates, increased frequency of HAIs, longer DMV, longer PICU stay, and fewer VFD. …”
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Dose‐exposure‐response of CARDALIS® (benazepril/spironolactone) on the classical and alternative arms of the renin‐angiotensin‐aldosterone system in healthy dogs by Elizabeth Manson, Jessica L. Ward, Maria Merodio, Emilie Guillot, Thomas Blondel, Karin Allenspach, Oliver Domenig, Jonathan P. Mochel

“…These results could help inform clinical trials in dogs with heart disease.…”
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Differential effects of clary sage (Salvia sclarea L.) oil and linalyl acetate on depression levels in diabetic foot ulcer patients with T2DM: a randomized blinded controlled trial by Ji Won Son, Purum Kang, Sun Seek Min, Geun Hee Seol, Geun Hee Seol

“…Patients were randomized to inhalation of 5% CS oil, 5% LA or almond oil (control) by natural breathing. Blood pressure, heart rate, Depression-VAS, Anxiety-VAS, and Stress-VAS were measured before and after inhalation.ResultsThis study enrolled 72 patients with DFU, including 43 with mild and 29 with moderate to severe depression. …”
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Mortality trends and disparities for coexisting chronic obstructive pulmonary disease and cardiovascular disease: A retrospective analysis of deaths in the United States from 1999-... by Aman Goyal, Humza Saeed, Wania Sultan, Ajeet Singh, Abdullah, Muhammad Khubaib Arshad, Zubair Amin, Mah I Kan Changez, Gauranga Mahalwar, Rozi Khan, Wael AlJaroudi

“…<h4>Background</h4>Chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD) greatly influence morbidity and mortality, with COPD patients frequently suffering from cardiovascular comorbidities like coronary heart disease and stroke. This study analyzes mortality trends and disparities among individuals in the United States (US) affected by both CVD and COPD.…”
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N-Cadherin promotes cardiac regeneration by potentiating pro-mitotic β-Catenin signaling in cardiomyocytes by Yi-Wei Tsai, Yi-Shuan Tseng, Yu-Shuo Wu, Wei-Lun Song, Min-Yi You, Yun-Chia Hsu, Wen-Pin Chen, Wei-Han Huang, Jia-Ci Chng, Chai-Ling Lim, Ke-Hsuan Wei, Shih-Lei Ben Lai, Wen-Chih Lee, Kai-Chien Yang

“…Abstract Adult human hearts exhibit limited regenerative capacity. Post-injury cardiomyocyte (CM) loss can lead to myocardial dysfunction and failure. …”
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Natural Antioxidant-Isoliquiritigenin Ameliorates Contractile Dysfunction of Hypoxic Cardiomyocytes via AMPK Signaling Pathway by Xiaoyu Zhang, Ping Zhu, Xiuying Zhang, Yina Ma, Wenguang Li, Ji-Mei Chen, Hui-Ming Guo, Richard Bucala, Jian Zhuang, Ji Li

“…We hypothesize that ISL as a natural antioxidant may protect heart against ischemic injury via modulating cellular redox status and regulating cardioprotective signaling pathways. …”
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Incidence of Hyperlipidemia among Adults Initiating Antiretroviral Therapy in the HIV Outpatient Study (HOPS), USA, 2007–2021 by Jun Li, Selom Agbobli-Nuwoaty, Frank J. Palella, Richard M. Novak, Ellen Tedaldi, Cynthia Mayer, Jonathan D. Mahnken, Qingjiang Hou, Kimberly Carlson, Angela M. Thompson-Paul, Marcus D. Durham, Kate Buchacz

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Using a robust model to detect the association between anthropometric factors and T2DM: machine learning approaches by Nafiseh Hosseini, Hamid Tanzadehpanah, Amin Mansoori, Mostafa Sabzekar, Gordon A. Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan

“…Method A dataset derived from the Mashhad Stroke and heart atherosclerotic disorders (MASHAD) study comprising 9354 subject aged 65 − 35. 25% (2336 people) of subjects were diabetic and 75% (7018 people) where non-diabetic was used for the analysis of 10 anthropometric factors and age that were measured in all patients. …”
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Croatian National Data and Comparison with European Practice: Data from the Cardiac Resynchronization Therapy Survey II Multicenter Registry by Sandro Brusich, Ivan Zeljković, Nikola Pavlovic, Ante Anić, Zrinka Jurišić, David Židan, Marina Klasan, Zlatko Čubranić, Kenneth Dickstein, Cecilia Linde, Camilla Normand, Sime Manola

“…Median age of the study population was 67 (61–73) years, and 21.2% were women. Primary heart failure (HF) aetiology was nonischemic in 61.1% of patients, and HF with wide QRS was the most common indication for the implantation (73.5%). 80% of patients had complete left bundle branch block, and over two-third had QRS ≥150 ms. …”
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Investigation of the Feasibility and Safety of a Highly Intensive Penetration Technique for Recanalization in Severe Calcified Femoropopliteal Occlusive Lesions: A Retrospective Ob... by Shinsuke Mori, Keisuke Hirano, Yusuke Setonaga, Toshihiko Kishida, Tomoya Fukagawa, Kohei Yamaguchi, Masafumi Mizusawa, Masakazu Tsutsumi, Norihiro Kobayashi, Yoshiaki Ito

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Treating chronic kidney disease in Danish primary care: results from the observational ATLAS study by Morten Lindhardt, Søren Tang Knudsen, Thomas Saxild, Morten Charles, Rikke Borg

“…Results Of the CKD study population (N = 1 497), 80% had hypertension, 32% diabetes (DM), 13% heart failure (HF), 59% no DM/HF. ACEis/ARBs were prescribed to 65%, statins to 56%, SGTL2is to 14%, and MRAs to 8% of all individuals. …”
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Relationship between Urinary Alzheimer-Associated Neuronal Thread Protein and Apolipoprotein Epsilon 4 Allele in the Cognitively Normal Population by Yuxia Li, Meimei Kang, Can Sheng, Guanqun Chen, Taoran Li, Jun Wang, Yanning Cai, Rong Wang, Ying Han

“…There were significant differences in urinary AD7c-NTP levels between subjects with and without a history of coronary heart disease or diabetes. Urinary AD7c-NTP levels were not related to years of education, nature of work, family history of dementia, a history of hypertension, stroke, anemia, or thyroid dysfunction. …”
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Epidemiological and molecular characteristics of extraintestinal pathogenic escherichia coli isolated from diseased cattle and sheep in Xinjiang, China from 2015 to 2019 by Xiaoxiao Gu, Qin Wu, Yingjin Chai, Xin Huang, Xia Zhou, Mengli Han, Tongzhong Wu, Xingxing Zhang, Fagang Zhong

“…Herein we isolated Extraintestinal pathogenic Escherichia coli (ExPEC) from the liver, spleen, lung, heart, and lymph nodes of infected cattle and sheep (Xinjiang, China), and phylogenetic grouping, serotyping, and multilocus sequence typing were performed to determine epidemic and molecular characteristics. …”
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The Relationship between Carotid Intima-Media Thickness and Ocular Circulation in Type-2 Diabetes by Kohei Ichinohasama, Hiroshi Kunikata, Azusa Ito, Masayuki Yasuda, Shojiro Sawada, Keiichi Kondo, Chihiro Satake, Hideki Katagiri, Toru Nakazawa

“…Furthermore, a logistic regression analysis showed that diabetes duration (OR, 1.11; P=0.006), diastolic blood pressure (OR, 0.93; P=0.025), heart rate (OR, 1.07; P=0.004), IMT (OR, 8.65; P=0.005), and CMT (OR, 1.03; P=0.007) were independent contributing factors to mild NPDR. …”
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Exploring the boundaries of anastomotic leak: experience in a high-volume center by Carolina Riscanevo Bobadilla, Gloria Flórez Dussan, Jorge Vargas, Liliana Suarez, German Jimenez, Carlos Gonzalez, Andrea Carolina Córdoba, Wilmar Martín, Diego Olivera, Raúl Guevara

“…Notably, 18.5% smoked, 11.1% had lung disease, and 9.3% had heart disease or diabetes. Chest tomography was used in 60% of cases, followed by endoscopy in 35.2%. …”
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Effects of dexmedetomidine combined with intravenous general anesthesia on hemodynamics and inflammatory factors in patients undergoing laparoscopic colorectal cancer surgery by Chunling Liu, Yong Gui, Min Zeng, Zhidong Zhou

“…Results: Systolic blood pressure (SBP) and diastolic blood pressure (DBP) at S1 and S2 in the experimental group were lower than in the control group (P <⁠0.05). Heart rate (HR) and mean arterial pressure (MAP) at S1, S2, and S3 in the experimental group were lower, as compared with the control group (P <⁠0.05). …”
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