Comprehensive Analysis of Metabolic Changes in Mice Exposed to Corilagin Based on GC-MS Analysis by Xu B, Wang C, Zhu X, Zhu L, Han G, Cui C

“…Using MetaboAnalyst 5.0 and the KEGG database was used to depict the 12 key metabolic pathways.Results: Compared with the control group, the Corilagin induced 20, 9, 11, 7, 16, 19, 14, 15, and 16 differential metabolites in the intestine, lung, kidney, stomach, heart, liver, hippocampus, cerebral cortex, and serum, respectively. …”
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Diabetes Increases Risk of Cardiovascular Events in Patients Receiving Permanent Pacemaker: A Propensity Score-Matched Cohort Study by Huang-Chung Chen, Wen-Hao Liu, Chien-Hao Tseng, Yung-Lung Chen, Wei-Chieh Lee, Yen-Nan Fang, Shaur-Zheng Chong, Mien-Cheng Chen

“…The primary outcome was cardiovascular events including heart failure (HF) hospitalization and acute myocardial infarction (AMI). …”
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The value of growth differentiation factor 15 as a biomarker for peripheral artery disease in diabetes patients by Wan-Chi Chuang, Chih-Hsun Chu, Cai-Sin Yao, Mei-Chih Wei, I-Lun Hsieh, Chia-Mei Liao

“…Increased age (p = 0.025 OR:1.02; 95% CI [0.13–0.87]), family history (p = 0.001 OR:1.37; 95%CI: [0.37–5.05]), heart failure (p = 0.002 OR:4.96; 95%CI: [1.76–13.97]), sodium-glucose linked transporter 2 (SGLT 2) inhibitor use (p = 0.026), estimated glomerular filtration rate (eGFR) (p = < 0.001), and uric acid (p = < 0.001) was also positively associated with high GDF15 levels. …”
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Selenium-enriched and ordinary green tea extracts prevent high blood pressure and alter gut microbiota composition of hypertensive rats caused by high-salt diet by Meirong Wu, Xiaobin Wu, Jiangxiong Zhu, Fanglan Li, Xinlin Wei, Yuanfeng Wang

“…Our results showed that GT and Se-GT supplementations significantly prevented the increase of blood pressure (BP), activated the phosphoinosmde-3-kinase/protein kinase B (PI3K/Akt) signaling pathway, and regulated the gene expression related to BP, as well as improved the tissue damage like heart, liver, and kidneys. Besides, the key parameters associated with oxidative stress, inflammation and endothelial dysfunction were also altered by GT and Se-GT treatments. …”
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PPARs: Nuclear Receptors Controlled by, and Controlling, Nutrient Handling through Nuclear and Cytosolic Signaling by Maria Moreno, Assunta Lombardi, Elena Silvestri, Rosalba Senese, Federica Cioffi, Fernando Goglia, Antonia Lanni, Pieter de Lange

“…., liver, skeletal muscle, heart, and white adipose tissue). We address the structure and function of the PPARs, and their interaction with other nuclear receptors, including PPAR cross-talk. …”
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Adapting self-measured blood pressure monitoring to reduce health disparities (ASPIRE): a pilot hybrid effectiveness‑implementation study protocol by Rasha Khatib, Nicole Glowacki, Iridian Guzman, Maureen Shields, Joseph Chase, Melanie Gordon

“…Despite advances in blood pressure management, significant racial and ethnic disparities persist, resulting in higher risks of stroke, heart disease, and mortality among non-White populations. …”
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Modeling Survival Time to Death among Stroke Patients at Jimma University Medical Center, Southwest Ethiopia: A Retrospective Cohort Study by Bikiltu Wakuma Negasa, Teramaj Wongel Wotale, Mesfin Esayas Lelisho, Legesse Kassa Debusho, Kibrealem Sisay, Wubishet Gezimu

“…Globally, stroke is the second-leading cause of death following ischemic heart disease. It is a public health burden for both developed and developing nations, including Ethiopia. …”
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A Pilot Study of Hemoglobin A1C Levels in Patients with Type 2 Diabetes after Creation of a Patient Assistance Program Enrollment Committee at a Student-Run Free Clinic by John D. Salvemini, Gregory R. Vance, Amanda Pham, Garner Fincher, Johnny Yang, Harshin Sanjanwala, Leonna Conley, Alan Penman, James Pitcock

“…ED visits and hospital admissions for heart attacks occurred only in the non-PAP group. …”
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Comparative, cross-sectional study of the format, content and timing of medication safety letters issued in Canada, the USA and the UK by Jeremy M Grimshaw, Margaret C Watson, Lise M Bjerre, Matthew Hogel, Cody D Black, Simon Parlow, David de Launay, Donald R Mattison

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Functional and Respiratory Capacity of Patients with Chronic Kidney Disease Undergoing Cycle Ergometer Training during Hemodialysis Sessions: A Randomized Clinical Trial by Antonio de Olival Fernandes, Yvoty Alves dos Santos Sens, Vivian Bertoni Xavier, Luiz Antonio Miorin, Vera Lúcia dos Santos Alves

“…Training intensity was aimed at keeping the heart rate between 50 and 70% of its maximum. All participants were evaluated before and after the eight consecutive weeks of follow-up and had biochemicals data, anthropometric, functional, and respiratory outcomes evaluated. …”
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Establishment of a Nomogram for Predicting Early Death in Viral Myocarditis by Xuejun Sun, Naxin Xie, Mengling Guo, Xuelian Qiu, Hongwei Chen, Haibo Liu, Hongmu Li

“…Combined with the actual clinical situation, the heart failure (HF) (OR: 2.13, 95% CI: 2.76–5.95), electrocardiogram (ECG) (OR: 6.11, 95% CI: 1.05–8.66), pneumonia (OR: 3.62, 95% CI: 1.43–9.85), brain natriuretic peptide (BNP) (OR: 4.66, 95% CI: 3.07–24.06), and lactate dehydrogenase (LDH) (OR: 1.90, 95% CI: 0.19–9.39) were finally used to construct the nomogram. …”
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The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A “Me Too” or “the Special One” Antidiabetic Class? by Ricardo Godinho, Cristina Mega, Edite Teixeira-de-Lemos, Eugénia Carvalho, Frederico Teixeira, Rosa Fernandes, Flávio Reis

“…In addition, other cytoprotective effects on other organs/tissues that are involved in serious T2DM complications, including the heart, kidney, and retina, have been increasingly reported. …”
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Randomized Controlled Study Comparing Use of Propofol Plus Fentanyl versus Midazolam Plus Fentanyl as Sedation in Diagnostic Endoscopy in Patients with Advanced Liver Disease by Sameh Abdelkhalik Ahmed, Amal Selim, Nehad Hawash, Ahmed Khaled Tawfik, Mohamed Yousef, Abdelrahman Kobtan, Rehab Badawi, Sally Elnawasany, Reham Abdelkader Elkhouly, Amr Shaaban Hanafy, Fatma H. Rizk, Loai Mansour, Sherief Abd-Elsalam

“…All patients were subjected to history taking, estimation of level of sedation, endoscopist rating, and hemodynamic parameters including oxygen saturation, heart rate, mean arterial pressure, incidence of side effect as (bradycardia, hypotension, hypoxia, nausea and vomiting, cough, shivering, or diplopia), time needed for complete recovery, and time needed for discharge. …”
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A vacuum lyophilization and bacterial tablet-based method for culture medium evaluation and potential use in probiotic products by Wen Cui, Liang Zhao, Yuwen Shi, Wei Feng, Xiao Chen, Hui Liu

“…We found that the recipe GBSS (Glycerinum, Brain Heart Infusion, Sucrose, Sodium Glutamate) showed the highest survival rate for Escherichia coli in vacuum freeze-drying. …”
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The Bipolar Depression Electrical Treatment Trial (BETTER): Design, Rationale, and Objectives of a Randomized, Sham-Controlled Trial and Data from the Pilot Study Phase by Bernardo de Sampaio Pereira Junior, Gabriel Tortella, Beny Lafer, Paula Nunes, Isabela Martins Benseñor, Paulo Andrade Lotufo, Rodrigo Machado-Vieira, André R. Brunoni

“…Biological markers such as blood neurotrophins and interleukins, genetic polymorphisms, heart rate variability, and motor cortical excitability will be assessed. …”
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Cardiovascular Disease Risk Factor Patterns and Their Implications for Intervention Strategies in Vietnam by Quang Ngoc Nguyen, Son Thai Pham, Loi Doan Do, Viet Lan Nguyen, Stig Wall, Lars Weinehall, Ruth Bonita, Peter Byass

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Clinical profile and outcomes in patients with moderate to severe aortic stenosis with or without concomitant chronic kidney disease by Jinghao Nicholas Ngiam, Ching-Hui Sia, Nicholas Wen Sheng Chew, Tze Sian Liong, Zi Yun Chang, Chi Hang Lee, Wen Ruan, Edgar Lik-Wui Tay, William Kok-Fai Kong, Huay Cheem Tan, Tiong-Cheng Yeo, Kian Keong Poh

“…The CKD group was older (78.0 ± 10.3 vs. 72.1 ± 12.9 years, P < 0.001), with a higher prevalence of hypertension, diabetes mellitus, hyperlipidaemia and ischaemic heart disease. AS severity did not differ significantly, but left ventricular (LV) mass index (119.4 ± 43.7 vs. 112.3 ± 40.6 g/m2, P = 0.027) and Doppler mitral inflow E to annular tissue Doppler e’ ratio (E: e’ 21.5 ± 14.6 vs. 17.8 ± 12.2, P = 0.001) were higher in the CKD group. …”
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Implications of the Intestinal Microbiota in Diagnosing the Progression of Diabetes and the Presence of Cardiovascular Complications by Alina Mihaela Leustean, Manuela Ciocoiu, Anca Sava, Claudia Florida Costea, Mariana Floria, Claudia Cristina Tarniceriu, Daniela Maria Tanase

“…Complications of diabetes may be macrovascular: such as stroke and ischemic heart disease as well as peripheral vascular and microvascular diseases—retinopathy, nephropathy, and neuropathy. …”
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Morphometric characteristics of organs of female chickens (Pazo de Vilane) supplemented with Curcuma longa by D. F. Maldonado Arias, J. M. Mira-Naranjo, D. I. Cajamarca Carrazco, J. I. García-Guerra, M. F. Baquero-Tapia, M. E. Sánchez-Salazar, E. M. Melendres-Medina, A. N. Montalvan-Cobo, S. A. Guamán-Rivera

“…In the morphometry of the upper organs, T1 indicated a shorter length of the esophagus (3.7 ± 0.5 mm; P < 0.002) and gizzard (4.9 ± 0.3 mm), but with a larger heart than the other treatments (P < 0.02). In addition, differences were evident in the liver, gallbladder and cecum (P = 0.01 to 0.001) that were more marked when C. longa was administered between 1 or 2 g/d. …”
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Enhancing Clinical Assessment of Skin Ulcers with Automated and Objective Convolutional Neural Network-Based Segmentation and 3D Analysis by Rosanna Cavazzana, Angelo Faccia, Aurora Cavallaro, Marco Giuranno, Sara Becchi, Chiara Innocente, Giorgia Marullo, Elia Ricci, Jacopo Secco, Enrico Vezzetti, Luca Ulrich

“…This condition mostly affects individuals over 65 years old and is often associated with chronic conditions such as diabetes, vascular issues, heart diseases, and obesity. Early detection, assessment, and treatment are crucial for recovery. …”
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