Effectiveness and Safety of the Coadministration of Rifampin and Warfarin versus Direct Oral Anticoagulants: A Cohort Study by Ju-Chieh Wung, Chia-Chen Hsu, Chi-En Wang, Yaa-Hui Dong, Chia-Chieh Lin, Szu-Yu Wang, Shih-Lin Chang, Yuh-Lih Chang

Get full text

Developing a new clinical governance framework for chronic diseases in primary care: an umbrella review by Walter Ricciardi, Gianfranco Damiani, Alessandra Buja, Vincenzo Baldo, Mark H Ebell, Roberto Toffanin, Mirko Claus

Get full text

Exercise intensity and reliability during recreational team handball training for 50–77-year-old unexperienced women by Rita Pereira, Peter Krustrup, Carlo Castagna, Carlos Resende, Ivone Carneiro, José Magalhães, Susana Póvoas

“…This study analyzed the physiological and physical demands of recreational team handbal (RTH) and the training sessions’ (matches) intensity variability in 50–77-year-old postmenopausal women ( n = 20) without prior experience with the sport. Heart rate (HR), blood lactate, rating of perceived exertion (RPE), distance covered, time spent in different locomotor categories, accelerations, decelerations, Player Load (PL), game actions and fun levels were evaluated in 245 matches, played indoor ( n = 130) or outdoor ( n = 115), as small sided games (3×15-min periods). …”
Get full text

Effects of Anti-Obesity Strategies on Bone Mineral Density: A Comprehensive Meta-Analysis of Randomized Controlled Trials by Myung Jin Kim, Seonok Kim, Han Na Jung, Chang Hee Jung, Woo Je Lee, Yun Kyung Cho

Get full text

Deaths during Sexual Activity by Agnė Okulevičiūtė, Sigitas Chmieliauskas, Sigitas Laima, Diana Vasiljevaitė, Jurgita Stasiūnienė

“…Concurrent findings included atherosclerotic changes in the heart, internal organ hyperemia and edema, hepatic steatosis, renal cyst, and a lack of ethyl alcohol in blood but 0.17 ‰ presence in urine according to toxicology analysis. …”
Get full text

N-Acetylcysteine Attenuates Diabetic Myocardial Ischemia Reperfusion Injury through Inhibiting Excessive Autophagy by Sheng Wang, Chunyan Wang, Fuxia Yan, Tingting Wang, Yi He, Haobo Li, Zhengyuan Xia, Zhongjun Zhang

“…NAC confers cardioprotection against diabetic heart I/RI primarily through inhibiting excessive autophagy which might be a major mechanism why diabetic hearts are less tolerant to I/RI.…”
Get full text

Association of non-selective β blockers with the development of renal dysfunction in liver cirrhosis: a systematic review and meta-analysis by Xiangbo Xu, Fangbo Gao, Ting Wang, Zuyao Yang, Qingchun Zhao, Xingshun Qi

“…Background & Aims Non-selective β blockers (NSBBs) may negatively influence renal function through decreasing heart rate and cardiac output. This study aimed to systematically investigate their association.Methods PubMed, EMBASE, and Cochrane library databases were searched to identify all relevant studies evaluating the association of NSBBs with renal dysfunction in cirrhotic patients. …”
Get full text

Excessive Daytime Sleepiness among Hypertensive US-Born Blacks and Foreign-Born Blacks: Analysis of the CAATCH Data by N. Williams, O. Abo Al Haija, A. Workneh, D. Sarpong, E. Keku, G. Ogedegbe, S. I. McFarlane, G. Jean-Louis

Get full text

Genome-Wide DNA Methylation in Mixed Ancestry Individuals with Diabetes and Prediabetes from South Africa by Tandi E. Matsha, Carmen Pheiffer, Stephen E. Humphries, Junaid Gamieldien, Rajiv T. Erasmus, Andre P. Kengne

Get full text

Mesothelioma in Two Nondomestic Felids: North American Cougar (Felis concolor) and Cheetah (Acinonyx jubatus) by Amanda Whiton, Juergen Schumacher, Erika E. Evans, Janelle M. Novak, Amanda Crews, Edward Ramsay, Robert Donnell

“…At necropsy, nodular masses decorated the pericardium at the level of the base of the heart. The final microscopic diagnosis was mesothelioma of the pericardium, tunica adventitia of the main pulmonary artery, left auricle epicardium, and left ventricular epicardium. …”
Get full text

A Comparison of the Braking and Propulsion Phase Characteristics of Traditional and Accentuated Eccentric Loaded Back Squats in Resistance-Trained Women by Brookelyn A. Campbell, Conor J. Cantwell, Lauren K. Marshall-Ciochon, Zachary S. Schroeder, Adam E. Sundh, Jack B. Chard, Christopher B. Taber, Timothy J. Suchomel

Get full text

Influence of Image Acquisition on Radiation Dose and Image Quality: Full versus Narrow Phase Window Acquisition Using 320 MDCT by Faisal Khosa, Atif Khan, Khurram Nasir, Waqas Shuaib, Matthew Budoff, Ron Blankstein, Melvin E. Clouse

“…Methods. 114 patients underwent coronary CTA study using 320-row MDCT scanner. 87 patients with mean age (61 + 13 years), mean BMI (29 + 6), and mean heart rate (HR) (58 + 7 bpm) were imaged at predefined 66–80% R-R interval and then reconstructed at 75% while 27 patients with mean age (63 + 16 years), mean BMI (28 + 5), and mean HR (57 + 7 bpm) were scanned throughout the complete R-R interval with tube current modulation. …”
Get full text

Development of a Mobile Application Platform for Self-Management of Obesity Using Artificial Intelligence Techniques by Sylvester M. Sefa-Yeboah, Kwabena Osei Annor, Valencia J. Koomson, Firibu K. Saalia, Matilda Steiner-Asiedu, Godfrey A. Mills

“…Obesity is a major global health challenge and a risk factor for the leading causes of death, including heart disease, stroke, diabetes, and several types of cancer. …”
Get full text

Serum biochemical profile in case of cardiorenal syndrome in cats with hypertrophic cardiomyopathy by Yu. A. Vatnikov, E. D. Sotnikova, V. I. Kuznetsov, A. A. Razumova, I. V. Shchurov, O. A. Petrukhina, A. A. Rudenko

“…Veterinary specialists have lately observed comorbidity of heart and kidney diseases known as cardiorenal syndrome. …”
Get full text

Combined MSC and GLP-1 Therapy Modulates Collagen Remodeling and Apoptosis following Myocardial Infarction by Elizabeth J. Wright, Nigel W. Hodson, Michael J. Sherratt, Moustapha Kassem, Andrew L. Lewis, Christine Wallrapp, Nadim Malik, Cathy M. Holt

“…Mesenchymal stem cells (MSCs) and glucagon-like peptide-1 (GLP-1) are being tested as treatment strategies for myocardial infarction (MI); however, their mechanisms in the heart are not fully understood. Methods. We examined the effects of MSCs, either native, or engineered to secrete a GLP-1 fusion protein (MSCs ± GLP-1), on human cardiomyocyte apoptosis in vitro. …”
Get full text

Nonalcoholic Fatty Liver Disease as a Potential Risk Factor for Cardiovascular Disease in Patients with Type 2 Diabetes: A Prospective Cohort Study by Mohammad Dehghani Firouzabadi, Amirhossein Poopak, Ali Sheikhy, Fatemeh Dehghani Firouzabadi, Fatemeh Moosaie, Soghra Rabizadeh, Sara Momtazmanesh, Manouchehr Nakhjavani, Alireza Esteghamati

“…., myocardial infarction, chronic heart disease, coronary artery bypass grafting, and percutaneous coronary intervention). …”
Get full text

The association between obesity indicators and mortality among individuals with hyperlipidemia: evidence from the NHANES 2003–2018 by Yiheng Zhang, Yajun Yao

“…Over an average follow-up period of 8.4 years, a total of 1,454 deaths were documented, 380 of which were related to heart diseases. Cox analysis manifested that, after adjusting covariates, increased WWI was linked to a higher likelihood of overall and CVD mortality (both P < 0.05). …”
Get full text

Perceived Nuisance Caused by Air Pollution on Amateur Endurance Athletes/Exercisers: Development of a Psychometric Scale by George Koskinas, Ilias Mavroidis, Yiannis Giossos

“…The most significant inconveniences that these amateur athletes/exercisers have to deal with, are related to breathing difficulty, increased heart rate, cough or respiratory problems, and eye or nose discomfort. …”
Get full text

Endoscopic retrograde cholangiopancreatography training using a silicone simulator fabricated using a 3D printing technique (with videos) by Suk Pyo Shin, Kyong Joo Lee, Min Je Sung, Jong Chan Kim, Guk Bae Kim, Moo Yeop Kim, Sung Yong Han, Sung Ill Jang, Mamoru Takenaka, Chang-Il Kwon

Get full text

Association between Shock Index and Emergency Department Cardiac Arrest by Chao-Tung Chen, Pei-Ming Wang, Chao-Hsin Wu, Chih-Wei Wei, Tai-Lin Huang

“…The shock index (SI) is defined as the ratio of heart rate to systolic blood pressure. It is a tool used for predicting the prognosis of critically ill and injured patients. …”
Get full text