High-reward, high-risk technologies? An ethical and legal account of AI development in healthcare by Maelenn Corfmat, Joé T. Martineau, Catherine Régis

“…While each one raises different questions depending on perspective, we propose three main legal and ethical priorities: education and training of healthcare professionals, offering support and guidance throughout the use of AI systems, and integrating the necessary ethical and legal reflection at the heart of the AI tools themselves. Conclusions By highlighting the main ethical and legal issues involved in the development and implementation of AI technologies in healthcare, we illustrate their profound effects on professionals as well as their relationship with patients and other organizations in the healthcare sector. …”
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Development and Validation of the RCOS Prognostic Index: A Bedside Multivariable Logistic Regression Model to Predict Hypoxaemia or Death in Patients with SARS-CoV-2 Infection by Gerardo Alvarez-Uria, Sumanth Gandra, Venkata R. Gurram, Raghu P. Reddy, Manoranjan Midde, Praveen Kumar, Ketty E Arce

“…The final model included 12 variables: age, systolic blood pressure, heart rate, respiratory rate, aspartate transaminase, lactate dehydrogenase, urea, C-reactive protein, sodium, lymphocyte count, neutrophil count, and neutrophil/lymphocyte ratio. …”
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Cardiovascular diseases in patients with cancer: A comprehensive review of epidemiological trends, cardiac complications, and prognostic implications by Ali A. Alshahrani, Evangelos Kontopantelis, Catharine Morgan, Rathi Ravindrarajah, Glen P. Martin, Mamas A. Mamas, Rongman Jia

“…Many chemotherapeutic agents used to treat cancer are associated with cardiovascular complications (such as heart failure, myocardial infarction, and thrombosis). …”
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Effect of Glycyrrhiza glabra L. on Broiler Growth Performance, Slaughter and Carcass Characteristics, Blood biochemistry, and Hematological Parameters: A Systematic Review by Esen Selim, Prete Andrea, Centoducati Gerardo, Lackner Maximilian, Palangi Valiollah, Tölü Cemil

“…Effects on abdominal fat and spleen weights were inconsistent, while liver, heart, and gizzard weights gen-erally increased. …”
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Expression of the Receptor for Advanced Glycation End Products in Epicardial Fat: Link with Tissue Thickness and Local Insulin Resistance in Coronary Artery Disease by Elena Dozio, Elena Vianello, Silvia Briganti, John Lamont, Lorenza Tacchini, Gerd Schmitz, Massimiliano Marco Corsi Romanelli

“…EAT samples were obtained from 33 patients undergoing open-heart surgery. EAT expression of RAGE, GLUT4, adiponenctin, GLO1, HMGB1, TLR-4, and MyD88 was analyzed by microarray. …”
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Fatigue State Evaluation of Urban Railway Transit Drivers Using Psychological, Biological, and Physical Response Signals by Hao Wu, Yubo Jiao, Chaozhe Jiang, Tong Wang, Jiangbo Yu

“…Moreover, we utilized heart rate signals, electrodermal activity, and eye movements from wearable devices and cameras to build a driver fatigue detection model with machine-learning methods. …”
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The Renal and Liver Complications Development among Patients with Type 2 Diabetes Mellitus in Kirkuk City by Wasan Talib Abed, Walaa Esmael Jassim, Emad Mohamed Rasheed

“… Diabetes is a chronic metabolic malady that has raised levels of blood glucose, which in last, it will cause severe harms to the heart, blood vessels, eyes, kidneys, and nerves. …”
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The modulating effect of coat color mutations on the generation and neutralization of reactive oxygen species in the Аmerican mink (Neovison vison) as a model by S. N. Sergina, V. A. Ilyukha, I. V. Baishnikova, T. N. Ilyina

“…The direcessive sapphire (a/a р/р) combination induced high levels of antioxidant enzymes’ activities as well as of thiobarbituric acid-reactive products (TBА-RPs), characterizing lipid peroxidation level. In heart tissue, coat color mutations exerted modulating effects on both RO S generation and the level of low-molecular-weight antioxidants. …”
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The Modification Effect of Influenza Vaccine on Prognostic Indicators for Cardiovascular Events after Acute Coronary Syndrome: Observations from an Influenza Vaccination Trial by Apirak Sribhutorn, Arintaya Phrommintikul, Wanwarang Wongcharoen, Usa Chaikledkaew, Suntara Eakanunkul, Apichard Sukonthasarn

“…The cardiovascular outcomes were described as major cardiovascular events (MACEs) which included mortality, hospitalization due to ACS, and hospitalization due to heart failure (HF). The stratified and multivariable Cox’s regression analysis was performed. …”
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Anomalous Left Coronary Artery Connected to the Pulmonary Artery in a 15-Year-Old Girl: Case Report and Discussion on Secondary Prevention of Sudden Death by Jérémy Laïk, Virginie Fouilloux, Philippe Aldebert, Linda Koutbi, Jérôme Hourdain, Philippe De Swardt, Fabrice Tiger, Anne Bellemain-Appaix, François Bernasconi, Laurent Jacq

“…Anomalous left coronary artery connected to the pulmonary artery (ALCAPA) is a rare congenital heart disease. Adaptive development of sufficient heterocoronary collaterality in the newborn may allow survival to a later age. …”
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Overwhelming Pulmonary Infection after a Tobogganing Accident by Ravinder Singh, Brian E Louie, William F Bennett, Christopher Allen, Tom Kelly, Christine H Lee

“…In the emergency department, the patient looked ill and was in distress. His heart rate was 125 beats/min, and he had a blood pressure of 103/61 mmHg, a respiratory rate of 20 breaths/min, a temperature of 38.5°C and an oxygen saturation of 94% on ambient air. …”
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Early Efficacy of In Situ Fenestration with a Triple Chimney Technique for High-Risk Stanford Type A Aortic Dissection: A Single-Center Retrospective Study by Qingsong Wu, Heng Lu, Debin Jiang, Zhihuang Qiu, Javed Rashid, Linfeng Xie, Yue Shen, Liangwan Chen

“…For patients who are eligible for open heart surgery, we still recommend it be performed.…”
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MicroRNA-221 protects myocardial contractility in myocardial ischemia/reperfusion injury through phospholamban. by Hongyu Li, Jimiao Qiu, Chang Liu, Guobing Yu, Danyu Wu, Yichun Chu, Kai Wang

“…Changes in the structural integrity of the mouse heart were identified with HE and MASSON staining, while TUNEL staining was used to evaluate the TUNEL-positive cells of cardiomyocytes. …”
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Physiological Characteristics of Type 1 Diabetes Patients during High Mountain Trekking by Bartłomiej Matejko, Andrzej Gawrecki, Marta Wróbel, Jerzy Hohendorff, Teresa Benbenek-Klupa, Dorota Zozulińska-Ziółkiewicz, Maciej T. Malecki, Tomasz Klupa

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Socioeconomic Assessment and Impact of Social Security on Outcome in Patients Admitted with Suspected Coronary Chest Pain in the City of Salta, Argentina by Ricardo A. León de la Fuente, Patrycja A. Naesgaard, Stein Tore Nilsen, Leik Woie, Torbjoern Aarsland, Harry Staines, Dennis W. T. Nilsen

“…Low socioeconomic status is associated with increased mortality from coronary heart disease. We assessed total mortality, cardiac death, and sudden cardiac death (SCD) in relation to socioeconomic class and social security in 982 patients consecutively admitted with suspected coronary chest pain, living in the city of Salta, northern Argentina. …”
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A study on the global patterns in the design and development of ventricular assist devices: a visualization approach by Ajay K. Sood, A. K. Prasada Rao

“…IntroductionVentricular assist devices (VADs) are lifesavers for people with advanced heart failure. The design of these devices has undergone drastic changes over time with the latest designs being far more efficient, small, lightweight, and more user-friendly. …”
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A One Session Gait Retraining Protocol with Metronome Augmentation Increases Cadence in Novice and Recreational Runners by Angie Huber, Dave Verhoff

“…Variables measured during the 12 Minute Cooper Run included distance, rate of perceived exertion (RPE), heart rate (HR), and 3-D biomechanics using inertial measurement units (IMUs). …”
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Acute Kidney Injury in a Case Series of Patients with Confirmed COVID-19 (Coronavirus Disease 2019): Role of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Blockade by Avantika Chenna, Venu Madhav Konala, Subhasish Bose, Sasmit Roy, Bhaskar Reddy Madhira, Vijay Gayam, Srikanth Naramala, Sreedhar Adapa

“…The renin-angiotensin system plays a very critical role in hypertension, diabetes, and kidney and heart diseases. The blockade of the renin-angiotensin system results in the prevention of progression of renal and cardiac damage. …”
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Comparative Effects of Verapamil, Nicardipine, and Nitroglycerin on Myocardial Ischemia/Reperfusion Injury by Hitoshi Yui, Uno Imaizumi, Hisashi Beppu, Mitsuhiro Ito, Munetaka Furuya, Hirofumi Arisaka, Kazu-Ichi Yoshida

“…From the present experimental results, verapamil and nitroglycerin rather than nicardipine did afford significant protection to the heart subjected to ischemia and reperfusion in a rabbit model.…”
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The effect of air-pollution and weather exposure on mortality and hospital admission and implications for further research: A systematic scoping review. by Mary Abed Al Ahad, Frank Sullivan, Urška Demšar, Maya Melhem, Hill Kulu

“…Hot and cold temperature was a risk factor for wide range of cardiovascular, respiratory, and psychiatric illness; yet, in few studies, the increase in temperature reduced the risk of hospital admissions for pulmonary embolism, angina pectoris, chest, and ischemic heart diseases. The role of effect modification in the included studies was investigated in terms of gender, age, and season but not in terms of ethnicity.…”
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