HIV Disease Progression to CD4 Count <200 Cells/μL and Death in Saskatoon, Saskatchewan by Stephanie Konrad, Stuart Skinner, Germain Bukassa Kazadi, Kali Gartner, Hyun June Lim

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Gestational exposure to environmental chemical mixtures and cognitive abilities in children: A pooled analysis of two North American birth cohorts by Jagadeesh Puvvula, Wei-Ting Hwang, Lawrence McCandless, Changchun Xie, Joseph M. Braun, Ann M. Vuong, Youssef Oulhote, Enrique F. Schisterman, Russell T. Shinohara, Linda Booij, Maryse F. Bouchard, Kristin Linn, Michael M. Borghese, Jean R. Seguin, Angelika Zidek, Christine Till, William Fraser, Kimberly Yolton, Kim M. Cecil, Jillian Ashley-Martin, Tye E. Arbuckle, Bruce Lanphear, Aimin Chen

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Immunization - Must Be Safe or We Will All Be Sorry by Greg Hammond

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A Randomized Trial of Yoga for Adolescents with Irritable Bowel Syndrome by Leora Kuttner, Christine T Chambers, Janine Hardial, David M Israel, Kevan Jacobson, Kathy Evans

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Heat-health messaging in Canada: A review and content analysis of public health authority webpages and resources by Emily J. Tetzlaff, Katie E. Wagar, Sarah J.I. Johnson, Melissa Gorman, Glen P. Kenny

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Contemporary Antiviral Drug Regimens for the Prevention and Treatment of Orolabial and Anogenital Herpes Simplex Virus Infection in the Normal Host: Four Approved Indications and 1... by Fred Y Aoki

“…Four drugs: acyclovir, famciclovir, valacyclovir and penciclovir, are currently licensed by the Therapeutics Products Directorate of Health Canada for the management of HSV infections. Although these drugs are only approved for four orolabial and anogenital infections in healthy persons, their efficacy and safety for 13 other related uses in this population have been demonstrated in controlled clinical trials, so called off-label uses. …”
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Asthma Education Program for First Nations Children: An exemplar of the Knowledge-to-Action Framework by Maureen L Douglas, Shawna L McGhan, Danielle Tougas, Nancy Fenton, Christopher Sarin, Oxana Latycheva, A Dean Befus

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A Case Report of Dramatically Increased Thyroglobulin after Lymph Node Biopsy in Thyroid Carcinoma after Total Thyroidectomy and Radioiodine by Mandana Moosavi, Stuart Kreisman

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Detection of Antibody to Envelope (E2) Antigen of Hepatitis C Virus by RK Chaudhary, E Burres

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In Vitro Activities of Ceftobiprole and Doripenem Tested against Frequently Encountered Aerobic and Facultative Gram-Positive and Gram-Negative Bacterial Pathogens Isolated from Pa... by James A Karlowsky, Mel DeCorby, Daryl J Hoban, George G Zhanel

“…BACKGROUND: In 2008, ceftobiprole was approved by Health Canada for the treatment of patients with complicated skin and skin structure infections including diabetic foot infections; approval of ceftobiprole by the United States Food and Drug Administration is pending. …”
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Potential Capsule Switching from Serogroup Y to B: The Characterization of Three such Neisseria meningitidis Isolates Causing Invasive Meningococcal Disease in Canada by Raymond SW Tsang, Dennis KS Law, Shaun D Tyler, Gwen S Stephens, Mark Bigham, Wendell D Zollinger

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The Emergence of Extensively Drug-Resistant Tuberculosis (TB): TB/HIV Coinfection, Multidrug-Resistant TB and the Resulting Public Health Threat from Extensively Drug-Resistant TB,... by Paul E Alexander, Prithwish De

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Putting the Evidence into Preceptor Preparation by Florence Myrick, Florence Luhanga, Diane Billay, Vicki Foley, Olive Yonge

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Analysis of Outbreak Data Reveals Factors Contributing to Salmonellosis Outbreaks Linked to Cantaloupes by Megan Rose-Martel, Sandeep Tamber

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Readability and Suitability of COPD Consumer Information by Kathryn Fullmann, David F. Blackburn, Mark E. Fenton, Holly Mansell

“…COPD inhalers were identified from the Health Canada Drug Product Database. Medication information and instructions for inhaler use were analyzed for readability by seven formulas, with an acceptability threshold of grades 6–8. …”
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Mucosal SARS-CoV-2 S1 adenovirus-based vaccine elicits robust systemic and mucosal immunity and protects against disease in animals by Najwa D. Aljehani, Levi Tamming, Muhammad Yasir Khan, Rwaa H. Abdulal, Mohamed A. Alfaleh, Aishah Ghazwani, Asalah Helal, Reem M. Alsulaiman, Mohammad A. Sanki, Khalid Alluhaybi, Farah Ayman Sukareh, Rahaf H. Alharbi, Faris H. Alyami, M-Zaki ElAssouli, Salima Shebbo, Wesam H. Abdulaal, Abdullah Algaissi, Ahmad Bakur Mahmoud, Mohammad Basabrain, Diana Duque, Jegarubee Bavananthasivam, Wangxue Chen, Lisheng Wang, Simon Sauve, Turki S. Abujamel, Tarfa Altorki, Rowa Alhabbab, Anh Tran, Xuguang Li, Anwar M. Hashem

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Requirements and special considerations for drug trials with children across six jurisdictions: 2. Ethics review in the regulatory approval process by Breanne Stewart, Pirkko Lepola, Gunter F. Egger, Fahimeda Ali, Albert J. Allen, Albert J. Allen, Alysha K. Croker, Andrew J. Davidson, Pamela Dicks, Saul N. Faust, Saul N. Faust, Dionna Green, Collin Hovinga, Collin Hovinga, Agnes V. Klein, Robyn Langham, Hidefumi Nakamura, Laura Pioppo, Shiva Ramroop, Michiyo Sakiyama, Isabel Sanchez Vigil de la Villa, Junko Sato, Donna L. Snyder, Mark A. Turner, Mark A. Turner, Sarah Zaidi, Kanecia Zimmerman, Kanecia Zimmerman, Thierry Lacaze-Masmonteil

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Spatial Variability and Application of Ratios between BTEX in Two Canadian Cities by Lindsay Miller, Xiaohong Xu, Amanda Wheeler, Dominic Odwa Atari, Alice Grgicak-Mannion, Isaac Luginaah

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Characterizing Radon Among Public Buildings and Small/Medium-Sized Businesses in a Canadian Province by Lily X. Yang, Tracy L. Kirkham, Laura Boksman, Anne-Marie Nicol, Paul A. Demers

“…The radon measurements ranged from <4 to 566 Bq/m³, with a median of 26 Bq/m³, arithmetic mean of 40.2 Bq/m³, and geometric mean of 26.9 Bq/m³. Using the Health Canada and Ontario labor guideline of 200 Bq/m³, 2.5% of participating workplaces had at least one measurement above this level; 7.2% were above the World Health Organization guideline. …”
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Percutaneous vacuum-assisted tumor thrombectomy using angiovac and penumbra lightning 12 aspiration systems by Murtaza Jafri, BSc, Brittany Stojak, MD, Owen Mooney, MD, Andrew Macdiarmid, MD, Ian W. Gibson, MD, Surinder Dhaliwal, MD

“…The patient's disease was not amenable to surgical resection and thrombolytic therapy was contraindicated due to associated intratumor hemorrhage, thus prompting consideration of thrombectomy under emergency approval from Health Canada. The patient underwent an overall successful total aspiration thrombectomy of the intracardiac tumor thrombus with subsequent resolution of her right heart strain, using the extracorporeal AngioVac aspiration system and partial aspiration of the extensive pulmonary emboli using the Penumbra Indigo Lightning 12 system. …”
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