Longitudinal immunogenicity cohort study of SARS-CoV-2 mRNA vaccines across individuals with different immunocompromising conditions: heterogeneity in the immune response and cruci... by Annalisa Ciabattini, Elena Pettini, Fabio Fiorino, Jacopo Polvere, Simone Lucchesi, Chiara Coppola, Simone Costagli, Gabiria Pastore, Anna Sicuranza, Monica Tozzi, Arianna Lippi, Francesca Panza, Monica Bocchia, Alessandro Bucalossi, Guido Garosi, David Bennett, Sonia Bernazzali, Massimiliano Fabbiani, Francesca Montagnani, Donata Medaglini

“…Funding: This work was supported by funds from the Department of Medical Biotechnologies of the University of Siena, and from EU within the NextGenerationEU-MUR PNRR Tuscany Health Ecosystem (Project no ECS00000017-THE).…”
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Logistic Regression Model in a Machine Learning Application to Predict Elderly Kidney Transplant Recipients with Worse Renal Function One Year after Kidney Transplant: Elderly KTbo... by Ubiracé Fernando Elihimas Júnior, Jamila Pinho Couto, Wallace Pereira, Michel Pompeu Barros de Oliveira Sá, Eduardo Eriko Tenório de França, Filipe Carrilho Aguiar, Diogo Buarque Cordeiro Cabral, Saulo Barbosa Vasconcelos Alencar, Saulo José da Costa Feitosa, Thais Oliveira Claizoni dos Santos, Helen Conceição dos Santos Elihimas, Emilly Pereira Alves, Marcio José de Carvalho Lima, Frederico Castelo Branco Cavalcanti, Paulo Adriano Schwingel

“…Renal replacement therapy (RRT) is a public health problem worldwide. Kidney transplantation (KT) is the best treatment for elderly patients’ longevity and quality of life. …”
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Modern theoretical-methodological and economic-legal problems of implementing the concept of sustainable development of tourism and recreation in Ukraine by Ion Dubovich, Alla Anishchenko, Nadia Yurkiv, Yuliia Volkovska, Rostyslav Matsko, Oleh Rozhkovych, Mariana-Nadiia Dubovich, Oksana Pylypiak

“…It is emphasized that the main problems that are currently hindering the implementation of the concept of sustainable development of tourism and recreation in Ukraine today are, first of all, the fact that hundreds of hectares of the territory of Ukraine are mined, the territories are contaminated with ammunition, large areas of the forest fund have been destroyed, the infrastructure has been destroyed, etc.It is noted that the Methodology for determining damage and losses, approved by the Ministry of Environmental Protection and Natural Resources of Ukraine, takes into account only a part of economic losses, while other significant losses that directly relate to the tourism and recreation industry (loss of life and health of the population of Ukraine, separation Ukrainian families, destroyed living conditions of Ukrainian citizens, damaged or destroyed residential buildings, moral, aesthetic and many other damages) are not taken into account.It is substantiated that for an objective assessment of damage and the amount of damage, it is also necessary to take into account environmental damage and destroyed natural resources, including mined and polluted hundreds of hectares of the territory of Ukraine, etc. …”
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Mucocutaneous Adverse Events in Patients With Cancer Treated with the Highly Selective RET Kinase Inhibitor Selpercatinib (LOXO-292) by Rachel E. Reingold, MD, Rose Parisi, MD, MBA, Guilherme Harada, MD, Andrea P. Moy, MD, George Dranitsaris, PhD, Jasmine H. Francis, MD, Julia Canestraro, OD, FAAO, Julia A. Lester, MPH, Lauren A. Kaplanis, RN, Dazhi Liu, PharmD, BCOP, Mario E. Lacouture, MD, Alexander Drilon, MD

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Influence of aquaculture practices on microbiota composition and pathogen abundance in pond ecosystems in South China by Shuhui Niu, Chuanlong Li, Jun Xie, Zhifei Li, Kai Zhang, Guangjun Wang, Yun Xia, Jingjing Tian, Hongyan Li, Wenping Xie, Wangbao Gong

“…Pond microbiota play a crucial role in maintaining water quality and the health of aquaculture species. This study aimed to explore the relationship between pond water and sediment microbiota (especially potential pathogens) and physicochemical parameters under different aquaculture conditions. …”
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The mediating effect of diabetes self-management between diabetes self-efficacy and glycemic control among patients with type 2 diabetes (自我管理在2型糖尿病患者自我效能和血糖控制间的中介效应)... by CHEN Shanshan (陈闪闪), GUO Hong (郭红), LIN Keke (林可可), WU Shishi (吴诗诗), FANG Jiaxin (方嘉欣)

“…Methods By means of convenience sampling, 210 patients with type 2 diabetes were investigated in Beijing Jimenli community health service center using diabetes management self-efficacy scale, diabetes self-management scale, and HbA1c. …”
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Research on Characteristics and Influencing Factors of High Temperature Disaster Risk in Wuhan Based on Local Climate Zone by Shujing GUO, Li ZHANG

“…ObjectiveAgainst the background of rapid urbanization and global warming, Wuhan is frequently hit by extreme heat events, which not only poses a serious threat to the health status of local residents, but also brings great losses to socio-economic development. …”
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Pragmatic algorithm for visual assessment of 4-Repeat tauopathies in [18F]PI-2620 PET Scans by Theresa Bauer, Matthias Brendel, Mirlind Zaganjori, Alexander M. Bernhardt, Alexander Jäck, Sophia Stöcklein, Maximilian Scheifele, Johannes Levin, Thilo van Eimeren, Alexander Drzezga, Osama Sabri, Henryk Barthel, Robert Perneczky, Günter Höglinger, Nicolai Franzmeier, Johannes Gnörich

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Safety and efficacy of oral administrated cepharanthine in non-hospitalized, asymptomatic or mild COVID-19 patients: a Double-blind, randomized, placebo-controlled trial by Jianyi Wei, Shupeng Liu, Yuexiang Bian, Lei Li, Biyun Qian, Zixuan Shen, Yan Zhang, Adila Abuduaini, Fuchen Dong, Xin Zhang, Jinhui Li, Yongpei Yu, Weituo Zhang, Jun Wang, Wei Zhai, Qixiang Song, Yu Zheng, Weihua Pan, Lanlan Yu, Qimin Zhan, Ning Zhang, Junhua Zheng, Shuming Pan, Chen Yao, Hai Li

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Association of quality of life in older patients with breast cancer: a cross-sectional study from China by Xi Chen, Qing Li, Xiang Wang, Lei Ji, Jintao Zhang, Qiao Li, Min Xiao, Shanshan Chen, Pin Zhang, Jiani Wang, Heng Cao, Xiaoyan Qian, Meng Xiu, Zhuoran Li, Yiqun Li, Xiaojuan Zheng

“…Objectives The purpose of this study was to investigate the quality of life (QoL) of older Chinese patients with breast cancer and to explore further the associations of functions, symptoms, financial burdens and comorbidities with global health/quality of life (gQoL).Design This was a cross-sectional study carried out following the Strengthening the Reporting of Observational Studies in Epidemiology checklist.Setting This study was conducted in two hospitals in Beijing from October 2021 to November 2022.Participants Patients with breast cancer aged over 65 years were included in the final analysis, which comprised a total of 481 patients.Primary and secondary outcome measures The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 and the Charlson Comorbidity Index (CCI) were used to assess patients’ QoL and comorbidities. …”
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Predictive and Cross-Validation Analysis of Aerobic and Anaerobic Performance Based on Maximum Strength by Alberto Souza Sá Filho, Pedro Augusto Inacio, Vicente Aprigliano, Patricia Sardinha Leonardo, Iransé Oliveira-Silva, Raphael Martins Cunha, Gaspar R. Chiappa, James Oluwagbamigbe Fajemiroye, Rodolfo P. Vieira, Rodrigo Alvaro Brandão Lopes-Martins, Marcelo Magalhães Sales

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Avaliação do sistema de Vigilância em Saúde das Populações Expostas a Substâncias Químicas, Brasil, 2011 a 2021 by Ana Paula Betaressi da Silva, Mariely Helena Barbosa Daniel, Vanessa de Paula Ferreira, Vitória Martins Chaves, Jéssika Angela Freitas de Oliveira, Adriana Rodrigues Cabral, Thiago de Brito Magalhães, Patrick Joseph Connerton, Luciana Nogueira de Almeida Guimarães, Camile de Moraes, e Orlando Marcos Farias de Sousa

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Clustering patients with COVID-19 according to respiratory support requirements, and its impact on short- and long-term outcome (RECOVID study) by Rosario Menéndez, Raúl Méndez, Ana Latorre, Paula González-Jiménez, Germán Peces-Barba, María Molina-Molina, Pedro Pablo España, Estela García, Angélica Consuegra-Vanegas, Marta María García-Clemente, Carolina Panadero, Juan Marco Figueira-Gonçalves, David De la Rosa-Carrillo, Oriol Sibila, María Dolores Martínez-Pitarch, Nuria Toledo-Pons, Cecilia López-Ramírez, Wanda Almonte-Batista, Abigail Macías-Paredes, Mercedes Villamon, Marisol Domínguez-Álvarez, Eli Nancy Pérez-Rodas, Javier Lázaro, Sarai Quirós, Rosa Cordovilla, Irene Cano-Pumarega, Antoni Torres

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Outer retina micro-inflammation is driven by T cell responses prior to retinal degeneration in early age-related macular degeneration by Lucas Stürzbecher, Lucas Stürzbecher, Lucas Stürzbecher, Lucas Stürzbecher, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Sylvia Bolz, Andjela Sekulic, Marius Ueffing, Marius Ueffing, Simon J. Clark, Simon J. Clark, Simon J. Clark, Nadine Reichhart, Sergio Crespo-Garcia, Nicola Wilck, Nicola Wilck, Nicola Wilck, Nicola Wilck, Olaf Strauß

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Co‐Translational Deposition of N6‐Acetyl‐L‐Lysine in Nascent Proteins Contributes to the Acetylome in Mammalian Cells by Dingyuan Guo, Nan Li, Xiaoyan Zhang, Runxin Zhou, Jie He, Xiao‐Ping Ding, Weixing Yu, Fuqiang Tong, Sibi Yin, Yu Wang, Xin Xu, Long Wang, Mingzhu Fan, Shan Feng, Ke Liu, Ke Tang, Zhuqing Ouyang, Yusong R Guo, Yugang Wang

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Durvalumab, Tremelimumab, and Platinum Chemotherapy in EGFR Mutation–Positive NSCLC: An Open-Label Phase 2 Trial (ILLUMINATE) by Chee Khoon Lee, PhD, Bin-Chi Liao, MD, Shalini Subramaniam, MMed (Clin Epi), Chao-Hua Chiu, MD, Antony J. Mersiades, MMed (Clin Epi), Chao-Chi Ho, MD, PhD, Chris Brown, MBiostats, Chun-Liang Lai, MD, PhD, Brett G.M. Hughes, M.B.B.S. (Hons), Tsung-Ying Yang, MD, PhD, Ken O’Byrne, MD, Yung-Hung Luo, MD, PhD, Sonia Yip, PhD, Ching-Liang Ho, MD, Victoria Bray, PhD, Wu-Chou Su, MD, PhD, Melissa Moore, PhD, Wei-Lien Feng, MS, Ya-Ying Bai, MS, Kate Ford, MHSc, Michelle M. Cummins, PhD, Martin R. Stockler, MSc (Clin Epi), Benjamin J. Solomon, PhD, Thomas John, PhD, James Chih-Hsin Yang, MD, PhD

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Practice of continuing care with Traditional Chinese Medicine nursing for patients after surgical treatment of mixed hemorrhoids in the specialized outpatient clinic (基于专病门诊的混合痔术后患... by Qin Shasha (秦沙沙), E Haiyan (鄂海燕), WEI Yongchun (魏永春), PENG Yujie (彭雨洁), TANG Ling (唐玲), LI Ye (李野), WANG Yali (王亚丽), DONG Yuxia (董玉霞)

“…Patients in the control group received routing telephone follow-up and health education after discharged form hospital, and those in the observation group were given continuing care with Traditional Chinese Medicine nursing in the specialized outpatient clinic, and a three-step integrated management of follow-up was carried out. …”
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Brown Adipose Tissue undergoes pathological perturbations and shapes C2C12 myoblast homeostasis in the SOD1-G93A mouse model of Amyotrophic Lateral Sclerosis by Marco Rosina, Silvia Scaricamazza, Flaminia Riggio, Gianmarco Fenili, Flavia Giannessi, Alessandro Matteocci, Valentina Nesci, Illari Salvatori, Daniela F. Angelini, Katia Aquilano, Valerio Chiurchiù, Daniele Lettieri Barbato, Nicola Biagio Mercuri, Cristiana Valle, Alberto Ferri

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Gastrointestinal complications of hepatic glycogen storage disease: a national survey questionnaire study in China by Xiaoyan Zhang, Zexiong Su, Jiaxing Wu, Hanshi Zeng, Xun Jiang, Ying Wang, Huiqing Shen, Xiaoli Xie, Yuan Xiao, Qing Tang, Xiaoping Luo, Xuemei Zhong, Huan Chen, Jiaoli Lan, Yongxin Chen, Xiaolu Zeng, Huiqiong Zhang, Zhiling Li, Yuxin Zhang, Min Yang

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Evidence construction of Silibinin capsules against alcoholic liver disease based on a meta-analysis and systematic review by Yan Wang, Yan Wang, Wenmin Yang, Wenmin Yang, Yuan Yang, Yuan Yang, Xingning Liu, Xingning Liu, Lanfen Peng, Lanfen Peng, Qi Huang, Qi Huang, Qi Huang, Kongli Fan, Kongli Fan, Rui Hu, Rui Hu, Jinyu Yi, Jinyu Yi, Xin Zhong, Xin Zhong, Jing Li, Jialing Sun, Xiaozhou Zhou, Xiaozhou Zhou

“…BackgroundIn recent years, the incidence of alcoholic liver disease (ALD) has rapidly increased worldwide, becoming a significant health issue. Silibinin capsules have shown potential in treating ALD, but clinical evidence is still insufficient. …”
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