Predictors of developing severe COVID-19 among hospitalized patients: a retrospective study by Hussain Abduljaleel Alkhalifa, Ehab Darwish, Zaenb Alsalman, Aman Alfaraj, Abdullah Alkhars, Fatimah Alkhalifa, Mohammed Algaraash, Ahmed Mohammed Elshebiny, Emad Alkhoufi, Khaled Mohamed Amin Elzorkany

“…BackgroundCOVID-19 poses a significant threat to global public health. As the severity of SARS-CoV-2 infection varies among individuals, elucidating risk factors for severe COVID-19 is important for predicting and preventing illness progression, as well as lowering case fatality rates. …”
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Suppressing recurrence in Sonic Hedgehog subgroup medulloblastoma using the OLIG2 inhibitor CT-179 by Yuchen Li, Chaemin Lim, Taylor Dismuke, Daniel S. Malawsky, Sho Oasa, Zara C. Bruce, Carolin Offenhäuser, Ulrich Baumgartner, Rochelle C. J. D’Souza, Stacey L. Edwards, Juliet D. French, Lucy S. H. Ock, Sneha Nair, Haran Sivakumaran, Lachlan Harris, Andrey P. Tikunov, Duhyeong Hwang, Coral Del Mar Alicea Pauneto, Mellissa Maybury, Timothy Hassall, Brandon Wainwright, Santosh Kesari, Gregory Stein, Michael Piper, Terrance G. Johns, Marina Sokolsky-Papkov, Lars Terenius, Vladana Vukojević, Leon F. McSwain, Timothy R. Gershon, Bryan W. Day

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Temporal trends of the utilization patterns of sedative-hypnotic medications in children, adolescents and young adults: a 21-year population-based study with joinpoint regression a... by Carltin Chun Ting Kwok, Heidi Ka Ying Lo, Ching Yui Chan, Joe Kwun Nam Chan, Corine Sau Man Wong, Calvin Pak Wing Cheng, Chung Ho, Brian Man Ho Leung, Wilfred Shone Horn Wong, Zoe Hoi Shuen Yu, Edwin Ho Ming Lee, Wing Chung Chang

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Metabolic and molecular Characterization, following dietary exposure to DINCH, Reveals new Implications for its role as a Metabolism-Disrupting chemical by Sontje Krupka, Alix Sarah Aldehoff, Cornelius Goerdeler, Beatrice Engelmann, Ulrike Rolle-Kampczyk, Kristin Schubert, Nora Klöting, Martin von Bergen, Matthias Blüher

“…Alternatives like diisononylcyclohexane-1,2-dicarboxylate (DINCH) are replacing traditional phthalates such as di-(2-ethylhexyl) phthalate (DEHP), which are now banned due to their proven harmful health effects. While DINCH is considered a safer alternative to DEHP and no adipogenic effects have been demonstrated in in vivo studies, recent research suggests that the primary metabolite, monoisononylcyclohexane-1,2-dicarboxylic acid ester (MINCH), promotes adipocyte differentiation and dysfunction in vitro. …”
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Multimodal Imaging of Patients With Gliomas Confirms C-MET PET as a Complementary Marker to MRI for Noninvasive Tumor Grading and Intraindividual Follow-Up After Therapy by Kai R. Laukamp MD, Florian Lindemann PhD, Matthias Weckesser MD, Volker Hesselmann MD, Sandra Ligges PhD, Johannes Wölfer MD, Astrid Jeibmann MD, Bastian Zinnhardt PhD, Thomas Viel PhD, Michael Schäfers MD, Werner Paulus MD, Walter Stummer MD, Otmar Schober PhD, MD, Andreas H. Jacobs MD

“…Binary logistic regression models were developed to differentiate between World Health Organization (WHO) tumor types/grades. Tumor sizes as defined by thresholding based on tumor-to-background ratios were significantly different as determined by MET-PET (21.6 ± 36.8 cm 3 ), T1w-Gd-MRI (3.9 ± 7.8 cm 3 ), and FLAIR/T2-MRI (64.8 ± 60.4 cm 3 ; P < .001). …”
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Aspergillus identification through bronchoscope in intensive care unit – a retrospective, databased cohort study by Hsin-I Cheng, Chun-Yu Lin, Chun-Yu Lin, Horng-Chyuan Lin, Horng-Chyuan Lin, Horng-Chyuan Lin, Shu-Min Lin, Shu-Min Lin, Shu-Min Lin, Shu-Min Lin, Meng-Heng Hsieh, Meng-Heng Hsieh, Yueh-Fu Fang, Yueh-Fu Fang, Po-Jui Chang, Po-Jui Chang, Wei-Syun Hung, Ko Cheng, Chung−Chi Huang, Chung−Chi Huang

“…This study investigated health outcomes among patients in ICUs with Aspergillus isolates identified using bronchoscopy.MethodsThis retrospective cohort study obtained data from the Chang Gung Research Database of Chang Gung Memorial Hospital. …”
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Understanding the mechanisms of hypoxia-induced tissue damage in fish: The role of GasderminEa/b in Larimichthys crocea by Lin Wang, Shuaiyu Chen, Yongyang Wang, Weini Zhang, Yinnan Mu, Yudong Jia, Changtao Guan, Meng Xue, Xinhua Chen

“…After simultaneous knockdown of Lcgsdmea/b in vivo, the liver exhibited better health compared to the control group, with less cell swelling and vacuolation. …”
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The effects of ultra-selective beta1-antagonism on the metabolic and cytokine profile in septic shock patients receiving noradrenaline: a sub-investigation from the STRESS-L Random... by Jarrod L. Thomas, Kirsty C. McGee, Anower Hossain, Gavin D. Perkins, Anthony C. Gordon, Duncan Young, Danny McAuley, Mervyn Singer, Ranjit Lall, Tina Kramaric, Janet M. Lord, Tony Whitehouse, Luis A. J. Mur, for the STRESS-L. collaborators

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Interactions between NAD+ metabolism and immune cell infiltration in ulcerative colitis: subtype identification and development of novel diagnostic models by Linglin Tian, Huiyang Gao, Tian Yao, Tian Yao, Yuhao Chen, Linna Gao, Jingxiang Han, Lanqi Zhu, He Huang, He Huang, He Huang

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Host-Induced Gene Silencing of the <i>Aspergillus flavus O</i>-Methyl Transferase Gene Enhanced Maize Aflatoxin Resistance by Olanike Omolehin, Yenjit Raruang, Dongfang Hu, Zhu-Qiang Han, Surassawadee Promyou, Robert L. Brown, Qijian Wei, Kanniah Rajasekaran, Jeffrey W. Cary, Kan Wang, Dan Jeffers, Zhi-Yuan Chen

“…Maize is one of the major crops that are susceptible to <i>Aspergillus flavus</i> infection and subsequent aflatoxin contamination, which poses a serious health threat to humans and domestic animals. Here, an RNA interference (RNAi) approach called Host-Induced Gene Silencing (HIGS) was employed to suppress the <i>O</i>-methyl transferase gene (<i>omtA</i>, also called <i>aflP</i>), a key gene involved in aflatoxin biosynthesis. …”
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Potential of multimodal large language models for data mining of medical images and free-text reports by Yutong Zhang, Yi Pan, Tianyang Zhong, Peixin Dong, Kangni Xie, Yuxiao Liu, Hanqi Jiang, Zihao Wu, Zhengliang Liu, Wei Zhao, Wei Zhang, Shijie Zhao, Tuo Zhang, Xi Jiang, Dinggang Shen, Tianming Liu, Xin Zhang

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Аналіз перинатальних наслідків у жінок із загрозою невиношування вагітності в першому триместрі залежно від факту утворення ретрохоріальної гематоми... by Yu.M. Duka, M.I. Yushchenko

“…Згідно з Адаптованою шкалою перинатального ризику Alberta Perinatal Health Program, до групи низького перинатального ризику віднесено 21 (35,0%) та 36 (46,7%) пацієнток, відповідно, середнього ризику - 30 (50,0%) та 32 (41,5%) жінок, а до групи високого ризику - 9 (15,0%) та 9 (11,7%); р>0,05. …”
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Life history, reproductive, and demographic parameters for bottlenose dolphins (Tursiops truncatus) in Sarasota Bay, Florida by Randall S. Wells, Aleta A. Hohn, Michael D. Scott, Jay C. Sweeney, Forrest I. Townsend, Jason B. Allen, Aaron A. Barleycorn, Katherine A. McHugh, Kim Bassos-Hull, Gretchen N. Lovewell, Deborah A. Duffield, Cynthia R. Smith, A. Blair Irvine

“…Detailed histories have been collected for resident individuals through integrated observations, systematic photographic identification surveys, tagging and tracking, catch-and-release health assessments, remote biopsy sampling, and stranding response. …”
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Chronic Mild Hyperglycemia in GCK-MODY Patients Does Not Increase Carotid Intima-Media Thickness by Stepanka Pruhova, Petra Dusatkova, Pavel J. Kraml, Michal Kulich, Zdena Prochazkova, Jan Broz, Jaroslav Zikmund, Ondrej Cinek, Michal Andel, Oluf Pedersen, Torben Hansen, Jan Lebl

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Construction of a diagnostic model for chronic mountain sickness among young male migrants to high-altitude areas by ZHANG Quan, CHEN Jian, LIU Bao

“…Early intervention can prevent the harm of CMS to the health of young men migrating to high-altitude areas. …”
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Rat Model of Cystic Neutrophilic Granulomatous Mastitis by Corynebacterium Kroppenstedtii by Wang M, Zeng Y, Liu M, Zhang D, Zhao D, Wang J, Liu Y, Zhao W

“…Mengjie Wang,1,2 Yifei Zeng,1,2 Min Liu,1 Dongxiao Zhang,1 Di Zhao,1,2 Junyue Wang,1,2 Yongxin Liu,1,2 Wenjie Zhao1 1Department of Galactophore, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, People’s Republic of China; 2School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, 100029, People’s Republic of ChinaCorrespondence: Dongxiao Zhang, Department of Galactophore, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, No. 23, Art Museum Back Street, Dongcheng District, Beijing, 100010, People’s Republic of China, Tel +86 13811077684, Email tzdx_thinking@126.comBackground: Cystic neutrophilic granulomatous mastitis (CNGM) poses a significant threat to the physical and mental health of women due to its increasing incidence, complex clinical manifestations. …”
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Efficacy of carbonyl cyanide-3-chlorophenylhydrazone in combination with antibiotics against Mycobacterium abscessus by Jifang Zheng, Qiang Liu, Haoran Wang, Fengmin Huo, Junnan Jia, Hairong Huang, Suting Chen

“…The use of CCCP as a potential treatment for M. abscessus infections shows promising results, especially when combined with other antibiotics to achieve a potent bactericidal effect.IMPORTANCEMycobacterium abscessus poses a significant public health threat due to its intrinsic resistance to a broad spectrum of conventional antibiotics. …”
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First detection and molecular characterization of Jingmen tick virus with a high occurrence in Rhipicephalus (Boophilus) microplus collected from livestock in Cameroon (2024) by Paloma Kiwan, Eva Lopez, Morena Gasparine, Geraldine Piorkowski, Agathe Colmant, Achille Paguem, Stephanie Mvodo, Laurence Thirion, Xavier de Lamballerie, Remi Charrel, Alessandra Falchi

“…As part of the surveillance for arboviral circulation, this study aimed to assess the presence of JMTV in ticks collected from livestock (cattle and sheep) in an area of the Akonolinga health district, Center Region, Cameroon. Methods A cross sectional study was carried out during the dry season between 5 and 14 March 2024. …”
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Sensory and Lipid Profile Optimization of Functional Brownies Through Cold-Pressed Nut Oil Substitution for Butter by Elena Martínez, José Emilio Pardo, Manuel Álvarez-Ortí, M. Esther Martínez-Navarro, Adrián Rabadán

“…Additionally, the levels of Vitamin E were higher in the 100% nut oil substitutions, offering potential health benefits. The sensory evaluation of the brownies showed that consumers preferred the reformulated versions, with higher scores for flavor, texture, and overall acceptability compared to the traditional recipe. …”
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Hubungan Kualitas Tidur dengan Prestasi Akademik Mahasiswa Program Studi Pendidikan Dokter Angkatan 2010 FK Universitas Andalas by Hanafi Nilifda, Nadjmir ., Hardisman .

“…The condition of sleep disorders commonly found among young adults, especially college students who can later cause a reduction in the concentration of learning and health problems. This can lead to failure to achieve optimal academic achievement because learning becomes impaired. …”
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