Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer by Yaojun Ren, Min Xue, Xinhui Hui, Xiuyu Liu, Muhammad Asad Farooq, Yiran Chen, Yuzhou Ji, Yixin Duan, Iqra Ajmal, Jie Yao, Wenzheng Jiang

“…Gastric cancer remains a significant global health burden, characterized by regional variations in incidence and poor survival prospects in advanced stages. …”
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Klebsiella pneumoniae derived outer membrane vesicles mediated bacterial virulence, antibiotic resistance, host immune responses and clinical applications by Lifeng Li, Xinxiu Xu, Ping Cheng, Zengyuan Yu, Mingchao Li, Zhidan Yu, Weyland Cheng, Wancun Zhang, Huiqing Sun, Xiaorui Song

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Knowledge, attitudes, and practices among physicians and pharmacists toward antibiotic use in sepsis by Jingmin Zhang, Jingmin Zhang, Haipeng Shi, Haipeng Shi, Yanmei Xia, Yanmei Xia, Zhenghua Zhu, Yaojun Zhang

“…This gap in research is concerning, considering its potential implications for patient outcomes and public health. This study aimed to assess the knowledge, attitudes and practices (KAP) among physicians and pharmacists toward antibiotic use in sepsis.MethodsThis web-based cross-sectional study was conducted at Shanxi Bethune Hospital between June 2023 and October 2023. …”
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Herb5GluCon: A novel polyherbal formulation with dual-action inhibiting properties against oxidative stress and glycoside hydrolases – an in silico and in vitro approach by Abbirami Balachandran, Patrick N. Okechukwu, Baskaran Gunasekaran, Jeleń Małgorzata, Beata Morak-Młodawska, Gabriele R.A. Froemming, Sameer Sapra, Charlie A. Lavilla, Jr., Merell P. Billacura, Salini D. Rajendran, Anis Najwa Abdul Rani, Anand Gaurav

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Single-cell RNA sequencing elucidates cellular plasticity in esophageal small cell carcinoma following chemotherapy treatment by Qinkai Zhang, Qinkai Zhang, Qinkai Zhang, Ziyu Gao, Ru Qiu, Jizhao Cao, Chunxiao Zhang, Wei Qin, Wei Qin, Meiling Yang, Meiling Yang, Xinyue Wang, Ciqiu Yang, Jie Li, Jie Li, Dongyang Yang, Dongyang Yang

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In-vitro effect of the methanolic extract of Morinda citrifolia against the life cycle of Dermatobia hominis by Dumar Alexander Jaramillo Hernández, Rafael Felipe Quevedo Carrillo, Diego Arnaldo Cadena Franco, Angélica Elizabeth Gonzalez Reina, Lida Carolina Lesmes-Rodríguez, Luz Natalia Pedraza-Castillo

“…Background: bovine cutaneous dermatobiosis or furuncular myiasis caused by Dermatobia hominis is a parasitosis that mainly affects bovines in the tropics and represents a particular interest in public health as zoonosis. Its control is based on ivermectins, which have long withdrawal times, affecting the productive dynamics within dairy cattle herds. …”
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A novel nomogram based on the patient’s clinical data and CT signs to predict poor outcomes in AIS patients by Jingyao Yang, Fangfang Deng, Qian Zhang, Zhuyin Zhang, Qinghua Luo, Yeyu Xiao

“…According to the National Institute of Health Stroke Scale (NIHSS) score 7 days after mechanical thrombectomy, the patients were divided into the good outcome group (<15) and the poor outcome group (≥15). …”
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MAF1 inhibits hepatocarcinogenesis by fostering an immunostimulatory tumor microenvironment by Di Cao, Shi-Juan Mai, Hui-yun Wang, Ge Ren, Yue-Ning Wang, Chao-Yue Sun, Haojiang Li, Yu-Feng Zhou, Mei-Yin Zhang, Shuo-Cheng Wang

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Development and Validation of Multiplex-PCR Assay for <i>β-Carotene hydroxylase</i> and <i>γ-Tocopherol methyl transferase</i> Genes Governing Enhanced Multivitamins in Maize for I... by Munegowda Manoj Gowda, Vignesh Muthusamy, Rashmi Chhabra, Hriipulou Duo, Saikat Pal, Nisrita Gain, Ashvinkumar Katral, Ravindra K. Kasana, Rajkumar U. Zunjare, Firoz Hossain

“…Traditional maize possesses low concentrations of provitamin-A and vitamin-E, leading to various health concerns. Mutant alleles of <i>crtRB1</i> and <i>vte4</i> that enhance β-carotene (provitamin-A) and α-tocopherol (vitamin-E), respectively, in maize kernels have been explored in several biofortification programs. …”
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Tibial stem extension versus standard configuration in primary cemented total knee arthroplasty: systematic review and meta-analysis by Arash Heidari, Mohammad H. Ebrahimzadeh, Mahla Daliri, Ali Moradi, Mahdieh Sahebi, Masoumeh Sadeghi

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Antimicrobial Residues in Poultry Litter: Assessing the Association of Antimicrobial Persistence with Resistant <i>Escherichia coli</i> Strains by Paula Cortés, Ekaterina Pokrant, Karina Yévenes, Aldo Maddaleno, Andrés Flores, María Belén Vargas, Lina Trincado, Matías Maturana, Lisette Lapierre, Javiera Cornejo

“…These findings highlight the need for stricter regulations on poultry litter management, including residue thresholds and resistance monitoring, to minimize environmental and public health risks. Proper treatment of poultry litter is essential to ensure its sustainable and safe re-use in agricultural systems.…”
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Dissemination of IncQ1 Plasmids Harboring NTE_KPC-IId in a Brazilian Hospital by Camila Maria dos Santos Boralli, Julian Andres Paganini, Rodrigo Silva Meneses, Camila Pacheco Silveira Martins da Mata, Edna Marilea Meireles Leite, Anita C. Schürch, Fernanda L. Paganelli, Rob J. L. Willems, Ilana L. B. C. Camargo

“…KPC is a clinically significant serine carbapenemase in most countries, and its rapid spread threatens global public health. <i>bla</i>_KPC transmission is commonly mediated by Tn<i>4401</i> transposons. …”
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Assembly mechanisms, not species pool, shape β-diversity of soil methanotrophic communities in steppes of China by Yongping Kou, Zhe Feng, Huan Li, Yanjiao Liu, Yanjiao Liu, Lin Xu, Lin Xu, Xiangzhen Li

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Preliminary Data on <i>Silybum marianum</i> Metabolites: Comprehensive Characterization, Antioxidant, Antidiabetic, Antimicrobial Activities, LC-MS/MS Profiling, and Predicted ADME... by Sabrina Lekmine, Ouided Benslama, Mohammad Shamsul Ola, Nabil Touzout, Hamza Moussa, Hichem Tahraoui, Haroun Hafsa, Jie Zhang, Abdeltif Amrane

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Oxytocin ameliorates lipopolysaccharide-induced acute orchitis model: interplay of oxidative stress and inflammatory pathways by Mohamed El-Sherbiny, Hany A. Elkattawy, Shimaa Hadhoud, Ahmed N. Nasr, Ateya M. Ibrahim, Ateya M. Ibrahim, Omar Z. Ameer, Noorhan Alsaleebi, Joud Asfari, Madaniah O. Zakari, Moaz A. Mojaddidi, Ehab K. Ali, Hailah M. Almohaimeed, Ahmed Abdeen, Sahar K. Ali, Mamdouh Eldesoqui, Mamdouh Eldesoqui

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Analysis of Role of Haematological Parameters in Diagnosis of Grampositive and Gram-negative Urinary Tract Infection: A Case-control Study by Sudha Srinivasan, Ayeesha Sithika Thajudeen, Kundhavai Chandrasekaran, Vijayashree Raghavan, D Roshini

“…Introduction: Urinary Tract Infections (UTIs) are a prevalent global health issue, primarily caused by bacterial infections. …”
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Addressing inter individual variability in CSF levels of brain derived proteins across neurodegenerative diseases by Sára Mravinacová, Sofia Bergström, Jennie Olofsson, Nerea Gómez de San José, Sarah Anderl-Straub, Janine Diehl-Schmid, Klaus Fassbender, Klaus Fliessbach, Holger Jahn, Johannes Kornhuber, G. Bernhard Landwehrmeyer, Martin Lauer, Johannes Levin, Albert C. Ludolph, Johannes Prudlo, Anja Schneider, Matthias L. Schroeter, Jens Wiltfang, Petra Steinacker, FTLD Consortium, Markus Otto, Peter Nilsson, Anna Månberg

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Gambaran Slide Malaria Berdasarkan Sediaan Darah dari Kepulauan Siberut Mentawai Periode Oktober 2011 – Januari 2012 by Adeline Sacharissa Firdaus, Nuzulia Irawati, Arni Amir

“…<br />Kata kunci: Malaria, Plasmodium falciparum, Plasmodium vivax, Parasit count</p><p>Abstract<br />Malaria is an important disease that has become a global health problem endemic in 105 countries and one of them is Indonesia. …”
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Improving future fish consumption: A case study on developing fish products for preschool children by Hui Jia, Zdeněk Fuka, Jan Hora, Magdalena Marešová, Věra Adámková, Koushik Roy, Jan Mraz

“…The omega-3 fatty acid content (Eicosapentaenoic Acid (EPA) + Docosahexaenoic Acid (DHA) 265 mg/ 100 g in fish ham to 1067 mg/ 100 g in fish sausages) exceeded recommended daily intake of EPA+DHA (>100 %; average 233 %), underscoring health benefits, especially from other boneless parts of fish beyond just fillets. …”
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WATER versus WATER II 5‐year update: Comparing Aquablation therapy for benign prostatic hyperplasia in 30–80‐cm3 and 80–150‐cm3 prostates by Mohamad Baker Berjaoui, David‐Dan Nguyen, Saud Almousa, Karim Daher, Neil Barber, Mo Bidair, Peter Gilling, Paul Anderson, Kevin C. Zorn, Gopal Badlani, Mitch Humphreys, Steven Kaplan, Ronald P. Kaufman Jr, Dean Elterman, Mihir Desai, Claus Roehrborn, Naeem Bhojani

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