Prior Anticoagulation and Risk of Hemorrhagic Transformation in Acute Stroke: A Post Hoc Analysis of the PRODAST Study by Gerrit M. Grosse, Anika Hüsing, Andreas Stang, Nils Kuklik, Marcus Brinkmann, Martin Grond, Jens D. Rollnik, Lars Marquardt, Andrea Kraft, Eckhard Schlemm, Carsten Eggers, Christoph C. Eschenfelder, Christian Weimar, Hans‐Christoph Diener

“…After adjustment for confounders (arterial hypertension, diabetes, heart failure, age, and sex), patients with prior anticoagulation had less severe strokes (−2.5 National Institutes of Health Stroke Scale points [95% CI, −2.8 to −2.2]), smaller infarct sizes (−23 mL [95% CI, −44 mL to −2 mL], n=4041), and reduced odds for hemorrhagic transformation (5% versus 10%; odds ratio, 0.48 [95% CI, 0.40–0.57]) compared with patients without antithrombotic treatment. …”
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Frequency of remission achievement in the pre-treat-to-target decade in juvenile idiopathic arthritis by Ana Isabel Rebollo-Giménez, Angela Pistorio, Silvia Maria Orsi, Francesca Ridella, Elena Aldera, Luca Carlini, Valentina Natoli, Marco Burrone, Silvia Rosina, Roberta Naddei, Alessandro Consolaro, Esperanza Naredo, Angelo Ravelli

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NF-κB/AP-1-Targeted Inhibition of Macrophage-Mediated Inflammatory Responses by Depigmenting Compound AP736 Derived from Natural 1,3-Diphenylpropane Skeleton by Van Thai Ha, Heung Soo Beak, Eunji Kim, Kwang-Soo Baek, Muhammad Jahangir Hossen, Woo Seok Yang, Yong Kim, Jun Ho Kim, Sungjae Yang, Jeong-Hwan Kim, Yung Hyup Joo, Chang Seok Lee, Joonho Choi, Hong-Ju Shin, Sungyoul Hong, Song Seok Shin, Jae Youl Cho

“…Since macrophage-mediated inflammatory responses are critical for skin health, here we investigated the potential anti-inflammatory activity of AP736. …”
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Effectiveness of antimicrobial agent combinations against carbapenem-producing Klebsiella pneumoniae with KPC variants in China by Congcong Liu, Congcong Liu, Yuchen Wu, Yanyan Zhang, Zelin Yan, Danxia Gu, Danxia Gu, Hongwei Zhou, Ning Dong, Chang Cai, Gongxiang Chen, Rong Zhang

“…PurposeCarbapenem-resistant Klebsiella pneumoniae (CRKP) producing carbapenemases poses a global threat to public health. Antimicrobial agent combinations have been promoted as a potential therapeutic strategy for infections. …”
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Immune correlates of early clearance of Mycobacterium tuberculosis among tuberculosis household contacts in Indonesia by Todia P. Setiabudiawan, Lika Apriani, Ayesha J. Verrall, Fitria Utami, Marion Schneider, Agnes R. Indrati, Pauline P. Halim, Paulina Kaplonek, Hadar Malca, Jessica Shih-Lu Lee, Simone J. C. F. M. Moorlag, L. Charlotte J. de Bree, Vera P. Mourits, Leo A. B. Joosten, Mihai G. Netea, Bachti Alisjahbana, Ryan P. McNamara, Galit Alter, Arjan van Laarhoven, James E. Ussher, Katrina Sharples, Valerie A. C. M. Koeken, Philip C. Hill, Reinout van Crevel

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Functional status, lymphocyte-to-monocyte ratio, and platelet-to-lymphocyte ratio as prognostic factors of one-year survival rate in elderly patients with advanced-stage non-small... by Ratna Nurhayati, Aulia Rizka, Cleopas Martin Rumende, Noorwati Sutandyo, Arif Hanafi, Edy Rizal Wahyudi, Hamzah Shatri, Anna Mira Lubis, Em Yunir, Muhammad Firdaus, Yuniar Harris Prayitno, Nadira Nibras Taqiyya

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Global research landscape and emerging trends of non-coding RNAs in prostate cancer: a bibliometric analysis by Yu-Liang Zhou, Yu-Liang Zhou, Wen-Liang Yao, Wen-Liang Yao, Sheng-Hui Chen, Sheng-Hui Chen, Peng Wang, Peng Wang, Jing-Wen Fu, Jing-Wen Fu, Jia-Qin Zhao, Jia-Qin Zhao, Jia-Yi Zhang, Jia-Yi Zhang

“…“circRNA” showed the highest burst strength among keywords, with “circRNA,” “EVs” and “exosome” maintaining sustained burst strength, suggesting these are the emerging research frontiers in this field.ConclusionInvestigating ncRNAs as pivotal research subjects in PC is essential for addressing the public health impact of the disease and advancing innovative diagnostic and targeted therapeutic strategies. …”
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Quality of Life and Related Factors in Discharged Patients with COVID-19 by Jinzhuo HU, Wenhuan WU, Jinwen SUN, Wei ZHANG, Shu CHENG, Zicheng GAO, Jinghua QIAN

“…In the"Questionnaire Star"platform from April to May 2020, the 12-item short form health survey version 2(SF-12V2) was used to evaluate life quality of life; the self-rating anxiety scale (SAS) was used to evaluate dyspnea anxiety status; the self-rating depression scale (SDS) was used to evaluate depression status; the modified medical research council dyspnea scores (mMRC) was used to evaluate difficulty of breathing. …”
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Physician’s perception and practices on antimicrobial resistance in a tertiary care hospital in Bangladesh: a cross-sectional study by Md Fuad Al Fidah, Md Abdullah Saeed Khan, Mohibbul Haque, Mohammad Rezaul Karim, Sabrin Shohid, Pilot Hossain, Rotna Rani Sen, Chaity Dey, Sumaiya Khan, Meherun Nahar Munni, Sonia Afroze Shopna, Razia Shultana, Nasreen Farhana, Shadman Sakib Choudhury

“…Background Antimicrobial resistance (AMR) is a global health and development concern. Antimicrobial misuse and overuse are key contributors to the emergence of drug-resistant infections.Objective The current study aimed to determine the level of perception and practices of physicians regarding AMR in a tertiary-level hospital.Design Cross-sectional study.Setting A tertiary care hospital in Dhaka, Bangladesh.Participants The study included 360 physicians who worked for more than 6 months in different departments of the hospital.Primary and secondary outcome measures Perceptions of AMR among physicians and secondary outcome measures were to find out the practices of physicians regarding AMR. …”
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Reproductive Efficiency of Nelore Cows in Fixed-Time Artificial Insemination Programs with Early Resynchronization by Larissa de Paiva Nunes Gonçalves, Alisson Jordão Prado, Aline Pacheco, Yana Eliza Feitosa de Almeida, Pietro Sampaio Baruselli, Welligton Conceição da Silva, Antônio Humberto Hamad Minervino, Jucelane Salvino de Lima, Kedson Alessandri Lobo Neves

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Distinctive dust weather intensities in North China resulted from two types of atmospheric circulation anomalies by Q. Huo, Q. Huo, Z. Yin, Z. Yin, Z. Yin, X. Ma, X. Ma, H. Wang, H. Wang, H. Wang

“…<p>Dust weather in North China (NC; 34–42° N, 105–120° E) has worsened in recent years, posing adverse impacts on the environment, human health, and the economy. A super dust storm that occurred on 15 March 2021 raised Beijing's PM<span class="inline-formula">₁₀</span> (particulate matter with a diameter less than 10 <span class="inline-formula">µ</span>m) concentrations above 7000 <span class="inline-formula">µ</span>g m<span class="inline-formula">⁻³</span>, while 2023 witnessed the highest spring dust weather frequency in nearly a decade. …”
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Men’s Attitudes Towards Participation in Organised Prostate Cancer Testing: An Abductive Thematic Analysis by Markus Arvendell, Lottie Phillips, Sara Delilovic, Moa Backman Enelius, Karin Olsson, Anetta Bolejko, Olof Akre, Sigrid Carlsson, Anne Richter, Anna Lantz

“…Barriers to participation included lack of time or motivation, fear of discovering illness, inaccessibility, and distrust of health care or medical procedures. Facilitators included a desire to confirm or rule out PCa, and taking advantage of the available screening opportunity. …”
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Potential use of beet-pulp concentrate supplementation in athletic horse by Luzilene Araujo de Souza, Monica Miranda Hunka, Sigismundo Fassbender de Rezende Júnior, Carolina Jones Ferreira Lima da Silva, Helena Emília Cavalcanti da Costa Cordeiro Manso, Joana Simões, Clarisse Simões Coelho, Francesco Fazio, Francesca Aragona, Hélio Cordeiro Manso Filho

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Understanding phage BX-1 resistance in Vibrio alginolyticus AP-1 and the role of quorum-sensing regulation by Xiaoyu Li, Xin Liu, Tianyi Ma, Haochen Su, Bingrui Sui, Lili Wang, Bilal Murtaza, Yongping Xu, Na Li, Demeng Tan

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Multicentre, multitime, multidimension, prospective follow-up cohort study on patients during the first wave of COVID-19 in China: a study protocol by Ming Zhang, Xuan Niu, Tonghui Liu, Chao Zheng, Huijie Yuan, Yanan Zhu, Huiping Liu, Shan Wu, Zhaoyao Luo, Jia Zhu, Danwei Hou, Tianhua Wei, Zhimin Zhu, Weipeng Huang, Weixian Bai, Xinyi Yu, Wenrui Bao

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Optimizing transcutaneous spinal stimulation: excitability of evoked spinal reflexes is dependent on electrode montage by Kelly Lynn Thatcher, Karen Emily Nielsen, Evan Blake Sandler, Oliver John Daliet, Jennifer Ann Iddings, Edelle Carmen Field-Fote

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Genomic detection of Panton-Valentine Leucocidins encoding genes, virulence factors and distribution of antiseptic resistance determinants among Methicillin-resistant S. aureus iso... by Masoud A. Juma, Tolbert Sonda, Boaz Wadugu, Davis Kuchaka, Mariana Shayo, Petro Paulo, Patrick Kimu, Livin E. Kanje, Melkiory Beti, Marco Van Zwetselaar, Blandina Mmbaga, Happiness Kumburu

“…Certainly, strengthening antimicrobial resistance surveillance and stewardship will ultimately reduce the selection pressure, improve the patient’s treatment outcome and public health in Tanzania.…”
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Cesarean section in Suriname using robson classification: a two-year nationwide cross-sectional study on rates, risk factors and perinatal outcomes of cesarean section by Zita D. Prüst, Josephine A. I. Dupont, Safir Liesdek, Kitty W. M. Bloemenkamp, Thomas van den Akker, Kim J. C. Verschueren, Lachmi R. Kodan

“…Abstract Background Optimizing CS performance is a global health priority, given the maternal and perinatal morbidity and mortality associated with both underuse and overuse. …”
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The Potential Proallergenic Activity of Tranzschelia pruni-spinosae and Phragmidium rubi-idaei in vitro Studies by Sztandera-Tymoczek M, Wdowiak-Wróbel S, Świderska U, Palusińska-Szysz M, Szuster-Ciesielska A

“…Furthermore, these fungi pose a potential health risk to humans, as they are major sources of allergens. …”
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Removal of cyanobacterial harmful algal blooms (HABs) from contaminated local park lake using Ganoderma lucidum mycelial pellets by Zarimah Mohd Hanafiah, Anggita Rahmi Hafsari, Malini Elango, Zul Ilham, Febri Doni, Wan Hanna Melini Wan Mohtar, Yusufjon Gafforov, Yong Jie Wong, Khairul Nizam Abdul Maulud, Nor Hidayah Ismail, Mohd Yusmiaidil Putera Mohd Yusof, Wan Abd Al Qadr Imad Wan-Mohtar

“…Eutrophication and hypereutrophication in lakes foster harmful blue-green algal blooms, which pose a significant threat to the ecological health of freshwater reservoirs. This study investigated the effectiveness of the bio-flocculation approach using the Ganoderma lucidum fungus strain BGF4A1 to remove these harmful blooms, specifically targeting cyanobacterial species like Microcystis PCC-7914. …”
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