Tolerability and Effectiveness of Regorafenib Treatment in Patients with Unresectable Hepatocellular Carcinoma: Real-World Data from the United States by Finn RS, Iyer R, Kalman RS, Parikh ND, Cabrera R, Babajanyan S, Kaseb AO

“…Richard S Finn,1 Renuka Iyer,2 Richard S Kalman,3 Neehar D Parikh,4 Roniel Cabrera,5 Svetlana Babajanyan,6 Ahmed O Kaseb7 1Department of Medicine, University of California, Los Angeles, CA, USA; 2Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY, USA; 3Department of Medicine, Einstein Medical Center, Philadelphia, PA, USA; 4Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA; 5Department of Medicine, University of Florida Health, Gainesville, FL, USA; 6US Medical Affairs, Oncology, Bayer Healthcare, Whippany, NJ, USA; 7Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USACorrespondence: Richard S Finn, Department of Medicine, University of California, Los Angeles, CA, USA, Tel +1-310-586-2091, Email rfinn@mednet.ucla.eduIntroduction: While several systemic therapies are available for unresectable hepatocellular carcinoma (uHCC), there is a lack of granular real-world evidence to support the efficacy and safety of these therapies. …”
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How Earth System Models Can Inform Key Dimensions of Marine Food Security in the Alaskan Arctic by Georgina A. Gibson, Hajo Eicken, Henry P. Huntington, Clara J. Deal, Olivia Lee, Katherine M. Smith, Nicole Jeffery, Josephine-Mary Sam

“…While communities monitor the abundance and health of food webs and environments as part of subsistence harvest practices, anticipating major transformations and changes in these systems is challenging. …”
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Feasibility of remote robot empowered teleultrasound scanning for radioactive patients by Ying Liang, Lu Wang, Manuel Escobar Amoresa, Zirui Jiang, Bo Yu, Jiami Li, Man Lu

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Exploring the role of different coping styles in mediating the relationship between dyadic adjustment status and postpartum depression among postnatal women: a single-centre, cross... by Jing Chen, Jing Deng, Fan Liu, Xiujing Guo, Yifei Tan

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Data-driven modeling of open circuit voltage hysteresis for LiFePO4 batteries with conditional generative adversarial network by Lisen Yan, Jun Peng, Zeyu Zhu, Heng Li, Zhiwu Huang, Dirk Uwe Sauer, Weihan Li

“…Third, the conditional matrix, incorporating temperature, health state, and historical paths, is constructed to provide the scenario-specific information for the adversarial network, thereby enhancing the model’s adaptability. …”
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Aflatoxins in Uganda: An Encyclopedic Review of the Etiology, Epidemiology, Detection, Quantification, Exposure Assessment, Reduction, and Control by Timothy Omara, Winfred Nassazi, Tom Omute, Aburu Awath, Fortunate Laker, Raymond Kalukusu, Bashir Musau, Brenda Victoria Nakabuye, Sarah Kagoya, George Otim, Eddie Adupa

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Imaging Diagnostics, Biomarkers, and Emerging Trends in Orthopedic Research and Treatment by Gabriela Oliwia Trestka, Wiktoria Domino, Urszula Zelik, Maria Przygoda, Joanna Śnieżna, Kamila Stępień, Sabina Adamczyk, Wojciech Florczak, Jagienka Włodyka, Jakub Dziewic, Karol Dzwonnik

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Construction of an Index System of the Biosafety Incident Response Capability for Nursing Staff: A Delphi Study by Chao Wu, Mengyi Hu, Xinyan Zhang, Mimi Fu, Lu Li, Qiang Xu, Xiaolan Guo, Hongjuan Lang

“…Results After two‐round Delphi survey, 28 nursing specialists from six provinces and cities around China, with expertise in three prevention research, epidemiology, military health service and biosafety incident rescue, established the index system of the biosafety incident response competence for nursing staff from April to May 2023. …”
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Evaluation of Phytochemical, Antioxidant, and Memory-Enhancing Activity of Garuga pinnata Roxb. Bark and Bryophyllum pinnatum (Lam) Oken. Leaves by Ravin Bhandari, Sabina Gyawali, Nisha Aryal, Devika Gaire, Kalpana Paudyal, Abaru Panta, Pooja Panth, Dirgha Raj Joshi, Rabindra Kumar Rokaya, Pramod Aryal, Jitendra Pandey

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A quantitative PCR to detect non-toxigenic Clostridioides difficile by Khurshida Begum, Hubert C. Chua, M. Jahangir Alam, Kevin W. Garey, Jinhee Jo

“…This innovative assay holds significant potential for applications in public health, infection control, diagnostic, and therapeutic strategies related to CDI.…”
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Comparison of Serum Potassium, MagnEsium, and Calcium Levels between Kanamycin and Capreomycin-BASEd Regimen-Treated MultiDrug-Resistant TuBerculosis Patients in Bandung (CEASE MDR... by Arto Yuwono Soeroto, Guntur Darmawan, Rudi Supriyadi, Panji Gugah Bhaskara, Prayudi Santoso, Bachti Alisjahbana, Ida Parwati

“…Moreover, our study supported the 2018 World Health Organization treatment guideline recommendations for removal of kanamycin and capreomycin from the MDR-TB regimens.…”
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A CRISPR/Cas12a electrochemical biosensing to detect pig mtDNA D-loop for ensuring food authenticity by Muhammad Ihda H.L. Zein, Clianta Yudin Kharismasari, Ari Hardianto, Salma Nur Zakiyyah, Riezki Amalia, Mehmet Ozsoz, Mara Mirasoli, Irkham, Yeni Wahyuni Hartati

“…One significant concern in food safety is the unintended inclusion of pork in products, which impacts food labeling, religious dietary practices, legal standards, and public health. Detecting such contamination is challenging due to complex food processing, requiring advanced methods for accurate identification. …”
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Aortic stenosis post-COVID-19: a mathematical model on waiting lists and mortality by Chris P Gale, Jonathan Weir-McCall, James H F Rudd, Mamas Mamas, Ramesh Nadarajah, Ben Gibbison, Louise Sun, Christian Philip Stickels, Houyuan Jiang, Kieran J Sharkey, Nick Holliman, Sara Lombardo, Lars Schewe, Matteo Sommacal, Katherine Cheema, Feryal Erhun

“…Objectives To provide estimates for how different treatment pathways for the management of severe aortic stenosis (AS) may affect National Health Service (NHS) England waiting list duration and associated mortality.Design We constructed a mathematical model of the excess waiting list and found the closed-form analytic solution to that model. …”
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Case report: dysgeusia, strawberry tongue, and psoriatic eruptions after combination treatment with adalimumab, sulfasalazine, and etoricoxib for ankylosing spondylitis by Binglin Cui, Jing Lin, Yuanchun Huang, Huachen Zhu, Huachen Zhu, Huachen Zhu, Jinbo Zou, Jiesheng Qin, Hui Pan, Hui Pan, Jian Chen

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A Review on Current Aspects of Curcumin-Based Effects in Relation to Neurodegenerative, Neuroinflammatory and Cerebrovascular Diseases by Claudia-Andreea Moldoveanu, Maria Tomoaia-Cotisel, Alexandra Sevastre-Berghian, Gheorghe Tomoaia, Aurora Mocanu, Csaba Pal-Racz, Vlad-Alexandru Toma, Ioana Roman, Madalina-Anca Ujica, Lucian-Cristian Pop

“…Curcumin is among the most well-studied natural substances, known for its biological actions within the central nervous system, its antioxidant and anti-inflammatory properties, and human health benefits. However, challenges persist in effectively utilising curcumin, addressing its metabolism and passage through the blood–brain barrier (BBB) in therapies targeting cerebrovascular diseases. …”
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Hubungan Merokok dengan Kejadian Hipertensi pada Laki-Laki Usia 35-65 Tahun di Kota Padang by Yashinta Octavian Gita Setyanda, Delmi Sulastri, Yuniar Lestari

“…As smoking habits increase the risk of hypertension, health promotion about the risk of blood pressure increasing in the patient who has a smoking habit should be done. …”
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Histological staining of tick bite skin biopsies for spirochetes and Powassan virus RNA by Jihane Oufattole, Anne Piantadosi, Sam R. Telford, Alvaro C. Laga, Isaac H. Solomon

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Salivary metabolomics in oral cancer: A systematic review by Rita Antonelli, Giacomo Setti, Nathaniel S. Treister, Thelma A. Pertinhez, Elena Ferrari, Mariana Gallo, Ronell Bologna-Molina, Paolo Vescovi, Marco Meleti

“…Two independent reviewers assessed the quality of the studies using a checklist proposed by the National Institutes of Health. They also assessed the level of evidence using the Oxford Center for Evidence-Based Medicine classification.Twenty-eight out of 9623 papers fulfilled the inclusion and exclusion criteria. …”
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Children’s Eating Behavior Questionnaire Correlated with Body Compositions of Thai Children and Adolescents with Obesity: A Pilot Study by Ekkarit Panichsillaphakit, Yuda Chongpison, Puthita Saengpanit, Tanisa Kwanbunbumpen, Jaraspong Uaariyapanichkul, Sirinuch Chomtho, Chitsanu Pancharoen, Chonnikant Visuthranukul

“…Obesity is a major threat to public health. Eating behavior and dietary intake of especially high energy-dense food with low nutrients contribute to the current epidemic of childhood obesity. …”
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Influence of Secondary Inorganic Aerosol on the Concentrations of PM2.5 and PM0.1 during Air Pollution Episodes in Hanoi, Vietnam by Nguyen-Quoc Dat, Bich-Thuy Ly, Trung-Dung Nghiem, Thu-Thi Hien Nguyen, Kazuhiko Sekiguchi, Truong-Thi Huyen, Thai-Ha Vinh, Le-Quang Tien

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