Production of β-lactoglobulin (BLG) gene knock- out blastocyst stage embryos of Indian water buffalo using CRISPR and SCNT technology by Aseem Tara, Priyanka Singh, Devika Gautam, Gaurav Tripathi, Shreya Malhotra, Sacchinandan De, Manoj K. Singh, Naresh L. Selokar

“…With the development of biotechnology, especially genome editing tools (CRISPRs), it is possible to generate new value-added products such as designer hypoallergenic milk for human health benefits. Keeping this in mind, we planned to utilize the CRISPR tools to disrupt the buffalo β-lactoglobulin (BLG) gene to produce hypoallergenic milk in the long run. …”
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Developing a Transparent Anaemia Prediction Model Empowered With Explainable Artificial Intelligence by Muhammad Sajid Farooq, Muhammad Hassan Ghulam Muhammad, Oualid Ali, Zahid Zeeshan, Muhammad Saleem, Munir Ahmad, Sagheer Abbas, Muhammad Adnan Khan, Taher M. Ghazal

“…The worldwide health epidemic of anaemia which is a condition with low levels of red blood cells or haemoglobin requires accurate prediction models to act promptly and improve patient outcomes because it is widespread and has different causes. …”
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Use of Complementary and Alternative Medicine Practices in Patients Admitted to The Pediatric Neurology Outpatient Clinic by Deniz Yüksel, Ergin Atasoy, Ülkühan Öztoprak, Erhan Aksoy, Fatih Mehmet Akif Özdemir, Halil Celik, Nesrin Ceylan

“…This study was approved with the decision number E-20-12-62 at the meeting dated 21.12.2020 of the Clinical Research Ethics Committee of SBU Ankara Dr Sami Ulus Gynecology and Childhood Health and Diseases Training and Research Hospital. …”
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Combining theory and usability testing to inform optimization and implementation of an online primary care depression management tool by Nicola McCleary, Justin Presseau, Isabelle Perkins, Brittany Mutsaers, Claire E. Kendall, Janet Yamada, Katharine Gillis, Douglas Green

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Phenotypic Characterization and Antibiotic Resistance Patterns of Extended-Spectrum β-Lactamase- and AmpC β-Lactamase-Producing Gram-Negative Bacteria in a Referral Hospital, Saudi... by Mutasim E. Ibrahim, Mohammed Abbas, Abdullah M. Al-Shahrai, Bahaeldin K. Elamin

“…Emergence of pathogenic bacteria carrying β-lactamase-resistant determinants has become a major health problem in the hospital setting. The study aimed to determine antibiotic-resistant patterns and frequency of extended-spectrum β-lactamase- (ESBL-) producing Gram-negative bacteria (GNB) and AmpC β-lactamase-producing GNB. …”
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Geospatial Data and Deep Learning Expose ESG Risks to Critical Raw Materials Supply: The Case of Lithium by Christopher J. M. Lawley, Marcus Haynes, Bijal Chudasama, Kathryn Goodenough, Toni Eerola, Artem Golev, Steven E. Zhang, Junhyeok Park, Eleonore Lèbre

“…., conservation, biodiversity, freshwater, energy, waste, land use, human development, health and safety, and governance) and a global dataset of news events to train and validate three models for predicting “conflict” events (e.g., disputes, protests, violence) that can negatively impact CRM supply chains: (1) a knowledge-driven fuzzy logic model that yields an area under the curve (AUC) for the receiver operating characteristics plot of 0.72 for the entire model; (2) a naïve Bayes model that yields an AUC of 0.81 for the test set; and (3) a deep learning model comprising stacked autoencoders and a feed-forward artificial neural network that yields an AUC of 0.91 for the test set. …”
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Predictors of Neurological and Functional Recovery in Patients with Moderate to Severe Ischemic Stroke: The EPICA Study by Manuel Murie-Fernández, Mercedes Molleda Marzo

“…Patients having suffered acute moderate to severe ischemic stroke of moderate to severe intensity within the previous 3 months with National Institutes of Health Stroke Scale (NIHSS) score from 10 to 20, 24 hours after arrival at emergency room (ER). …”
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Influence of lemongrass and oregano essential oils and their combination on in vitro ruminal fermentation and greenhouse gas emissions in total mixed ration for dairy cows by Sara Glorio Patrucco, Alessandro Lotto, Martina Dorigo, Rita Fornaciari, Antonio Sagliano, Nicola Martinelli, Alessandra Cosani, Khalil Abid, Salvatore Barbera, Hatsumi Kaihara, Sonia Tassone

“…Essential oils (EOs) are emerging as natural feed additives in ruminants’ nutrition to enhance animal health, performance and reduce environmental footprint. …”
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Dose–response relationship between sedentary time and anxiety and the moderating effect of a 10-min walk: a cross-sectional study by Zheng Tian, Yimiao Li, Nan Zhang, Yong Liu, Yibo Wu, Lan Wang

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Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy Device for Lymphadenopathy by Yuki Tanisaka, Masafumi Mizuide, Akashi Fujita, Tomoya Ogawa, Ryuichiro Araki, Masahiro Suzuki, Hiromune Katsuda, Youichi Saito, Kazuya Miyaguchi, Tomoaki Tashima, Yumi Mashimo, Masami Yasuda, Shomei Ryozawa

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Patients’ and plastic surgeons’ experiences with an online patient decision aid for breast reconstruction: considerations for nationwide implementation by Jacqueline A. ter Stege, Ellen G. Engelhardt, Leonie A.E. Woerdeman, Hester S.A. Oldenburg, Jacobien M. Kieffer, Daniela E.E. Hahn, Frederieke H. van Duijnhoven, Martine A. van Huizum, Regina The, Klemens Karssen, Marianne Kuenen, Miranda A. Gerritsma, Quinten (PQ) Ruhe, Irene S. Krabbe-Timmerman, Martijne van’t Riet, Nikola (AN) Kimmings, Eveline M.L. Corten, Kerry A. Sherman, Arjen J. Witkamp, Eveline M.A. Bleiker

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The role of endothelial cell-related gene COL1A1 in prostate cancer diagnosis and immunotherapy: insights from machine learning and single-cell analysis by Gujun Cong, Jingjing Shao, Feng Xiao, Haixia Zhu, Peipei Kang

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Thyme Essential Oil as a Potential Tool Against Common and Re-Emerging Foodborne Pathogens: Biocidal Effect on Bacterial Membrane Permeability by Martina Di Rosario, Leonardo Continisio, Giuseppe Mantova, Francesca Carraturo, Elena Scaglione, Daniela Sateriale, Giuseppina Forgione, Chiara Pagliuca, Caterina Pagliarulo, Roberta Colicchio, Mariateresa Vitiello, Paola Salvatore

“…Over the past decade, foodborne diseases have become a significant public health concern, affecting millions of people globally. …”
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Asthma and obesity increase inflammatory markers in children by Harshita Shailesh, Safa Noor, Lena Hayati, Antonisamy Belavendra, Nicholas Van Panhuys, Abdul Badi Abou-Samra, Stefan Worgall, Ibrahim Janahi, Ibrahim Janahi

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Evidence in Practice of Tissue Healing with Latex Biomembrane: Integrative Review by Suélia de Siqueira Rodrigues Fleury Rosa, Mário Fabrício Fleury Rosa, Marcos Augusto Moutinho Fonseca, Glécia Virgolino da Silva Luz, Carlos Federico Domínguez Avila, Aldira Guimarães Duarte Domínguez, Aldene Guimarães Duarte Dantas, Von Braun Richter

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Anisodamine ameliorates crystalline silica-exposed pulmonary inflammation and fibrosis via the α7nAChR/JAK2/STAT3 signaling pathway by Meng Liu, Hui Liu, Hong Kang, Juan Wu, Puhua Xing, Xiaorui Ding, Yangyang Wei, Xiaomei Kong

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Factors Associated With the Recovery of Left Ventricular Ejection Fraction in Patients With Anthracycline-Induced Left Ventricular Dysfunction by Tyler Shugg PharmD, PhD, Tk Nguyen PharmD, Xuesi Hua BS, Blair Richards MPH, James Rae PhD, Robert Dess MD, Daniel Perry MD, Bradley Kay MD, Salim S. Hayek MD, Monika Leja MD, Jasmine A. Luzum PharmD, PhD

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Risk factors for growth retardation in children with juvenile idiopathic arthritis: a case-control study by Ying Zhang, Liping Song, Weihu Ma, Ye Wang, Peipei Wang, Xiaolin Zhang, Zhe Zhang, Yuan Zhang, Qianhui Yu, Yang Yu, Lin Zhang

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Impact of fish oil supplementation on plasma levels of highly unsaturated fatty acid-containing lipid classes and molecular species in American football athletes by Veronica Anne Mullins, Justin M. Snider, Bryce Michael, Lydia Rose Porter, Roberta Diaz Brinton, Floyd H. Chilton

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Phylogeography and biological characterization of H12N2 virus isolated from whooper swan in Central China by Pengfei Ren, Zhen Gao, Xing Li, Jiao Tang, Pei Li, Zhonglin Huang, Jinchi Guo, Pengfei Cui, Lin Jin, Junping Li, Libin Liang

“…When AIVs originating from wild birds cross species barriers to infect mammals or humans, they pose a significant threat to public health. The H12 subtype of AIVs primarily circulates in wild birds, with relatively few isolates reported worldwide, and the evolutionary and biological characteristics of H12 subtype AIVs remain largely unknown. …”
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