Definition of clinical immunology around the globe by José C. Crispín, José C. Crispín, José C. Crispín, Tineke Cantaert, Tineke Cantaert, Alberto Pinzon-Charry, Alberto Pinzon-Charry, Alberto Pinzon-Charry, Domenico Mavilio, Domenico Mavilio, Domenico Mavilio, Ahmed Seri, Ahmed Seri, Pierre Miossec, Pierre Miossec

“…We found that though the number of diseases and processes in which immune mechanisms are involved has considerably grown, 90% of participants agree with the 1993 World Health Organization definition of Clinical Immunology. …”
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A Comprehensive Review on the Effects of Laser Photobiomodulation on Skeletal Muscle Fatigue in Spastic Patients by Sadi F. Stamborowski, Fernanda Púpio Silva Lima, Patrícia Sardinha Leonardo, Mário Oliveira Lima

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Protocol for the systematic review of age and sex in preclinical models of age-correlated diseases [version 2; peer review: 2 approved] by Céline Heinl, Ines Schadock, Maximilian Wurm, Paul Lucas Wildner, Daniel Butzke, Bettina Bert, Alexandra Bannach-Brown, Matthias Steinfath, Kai Diederich

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Association between fibrinogen-to-albumin ratio and bone metabolism markers (β-CTX and P1NP) in Chinese individuals with osteoporotic fracture: a cross-sectional investigation by Li-long Feng, Ke Lu, Chong Li, Min-zhe Xu, Yao-wei Ye, Yi Yin, Hui-qiang Shan

“…The study may provide a novel clinical implication by introducing FAR as a potential reference indicator for assessing bone health, offering a cost-effective and conveniently obtainable biomarker to monitor inflammation to improve bone metabolism in the treatment of osteoporosis.…”
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Perioperative infections as a prognostic risk factor in hepatocellular carcinoma and cholangiocellular carcinoma: a comparative analysis by Markus S. Jördens, Hannah C. Oswald, Lisa Heinrichs, Nathalie Gassmann, Linda Wittig, Tom Luedde, Sven H. Loosen, Christoph Roderburg, Wolfram T. Knoefel, Georg Fluegen

“…Abstract Background Hepatocellular Carcinoma (HCC) and cholangiocellular adenocarcinoma (CCA) are the most common primary liver tumors representing a major global health burden. In early disease stages, tumor resection may provide long-term survival in selected patients. …”
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Actors influencing cancer-related fatigue and the construction of a risk prediction model in lung cancer patients by Mei-Ning Zhang, Yi-Chen Zhou, Zhu Zeng, Cun-Liang Zeng, Bo-Tao Hou, Gui-Rong Wu, Qiao Jiao, Dai-Yuan Ma

“…A questionnaire survey was conducted using the Revised Piper Fatigue Scale (PFS-R), Pittsburgh Sleep Quality Index (PSQI), and Hospital Anxiety and Depression Scale (HADS) to collect data on patient demographics and sociological characteristics, disease-related information, physiological indicators, sleep quality, mental health, and other relevant factors. To explore the factors influencing CRF in lung cancer patients, single-factor analysis and multiple logistic regression analysis were performed. …”
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Characterization of Triterpene Saponin Composition of White, Yellow and Red Beetroot ( Beta vulgaris L.) by Aneta Spórna-Kucab, Anna Tekieli, Krystyna Skalicka-Woźniak, Agnieszka Grzegorczyk, Tomasz Świergosz, Sławomir Wybraniec

“…Beta vulgaris L. is an important source of bioactive saponins – a group of secondary metabolites – that have spurred a growing interest due to their health-promoting properties. This study aimed to gain information on triterpene saponin profile of the peel and flesh of white, yellow and red beet of six cultivars – Snow Ball, Boldor, Ceryl, Chrobry, Forono and Tytus – harvested in Poland, in the same region. …”
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Beyond Chemistry: Investigating the Physical, Pharmacological, and Computational Aspects of Polyoxometalate Integrated Solid Lipid Nanoparticles for Cancer Treatment by Khan R, Tulain UR, Shah HS, Usman F, Chohan TA, Iqbal J, Kazi M, Ijaz M, Erum A, Malik NS, Mahmood A

“…Riffat Khan,1 Ume Ruqia Tulain,1 Hamid Saeed Shah,2 Faisal Usman,3 Tahir Ali Chohan,2 Jamshed Iqbal,4 Mohsin Kazi,5 Muhammad Ijaz,6 Alia Erum,1 Nadia Shamshad Malik,7 Arshad Mahmood8,9 1Faculty of Pharmacy, University of Sargodha, Sargodha, 40100, Pakistan; 2Institute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan; 3Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, 66000, Pakistan; 4Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad, 22060, Pakistan; 5Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia; 6Department of Pharmacy, COMSATS University Islamabad, Lahore Campus, Lahore, Pakistan; 7Faculty of Pharmacy, Capital University of Science and Technology, Islamabad, Pakistan; 8College of Pharmacy, Al-Ain University, Abu Dhabi Campus, Abudhabi, United Arab Emirates; 9AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab EmiratesCorrespondence: Ume Ruqia Tulain; Muhammad Ijaz, Email umeruqia.tulain@uos.edu.pk; drmijaz@cuilahore.edu.pkPurpose: The solid lipid nanoparticles of transitional metal complexes (POMs) were prepared with natural lipids with the aim of developing a safer therapeutic approach for cancer treatment.Methods: Natural lipids were used to create solid lipid nanoparticles containing transitional metal complexes (POMs).Results: The nanoparticles had displayed appreciable entrapment and loading percentage of P5W30. …”
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Major Adverse Kidney Events in Hospitalized Older Patients With Acute Kidney Injury: Machine Learning–Based Model Development and Validation Study by Xiao-Qin Luo, Ning-Ya Zhang, Ying-Hao Deng, Hong-Shen Wang, Yi-Xin Kang, Shao-Bin Duan

“… BackgroundAcute kidney injury (AKI) is a common complication in hospitalized older patients, associated with increased morbidity, mortality, and health care costs. Major adverse kidney events within 30 days (MAKE30), a composite of death, new renal replacement therapy, or persistent renal dysfunction, has been recommended as a patient-centered endpoint for clinical trials involving AKI. …”
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Phenolic Compounds from Water-Ethanol Extracts of Tetrapleura tetraptera Produced in Cameroon, as Potential Protectors against In Vivo CCl4-Induced Liver Injuries by Peter William Kemewele Saague, Bruno Moukette Moukette, Jacques Romain Njimou, Prosper Cabral Nya Biapa, Francine Nzufo Tankeu, Vicky Joseline Ama Moor, Constant Anatole Pieme, Jeanne Yonkeu Ngogang

“…Liver diseases are a global health problem. Medicinal plants are being increasingly used to manage a wide variety of diseases including liver disorders. …”
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OMEGA-3 Fatty Acids Retention, Oxidative Quality, and Sensoric Acceptability of Spray-Dried Flaxseed Oil by Muhammad Zia Shahid, Muhammad Imran, Muhammad Kamran Khan, Muhammad Haseeb Ahmad, Muhammad Nadeem, Niaz Muhammad, Adeela Yasmin

“…Oxidation of omega-3 fatty acids during processing and storage results in reduced shelf stability of food products and limited health potentials. Spray-drying is considered a processing technique to shield omega-3 fatty acids from oxidative damage. …”
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GnIH secreted by green light exposure, regulates bone mass through the activation of Gpr147 by Yu You, Konglin Huo, Liang He, Tongyue Wang, Lei Zhao, Rong Li, Xiaoqing Cheng, Xuebin Ma, Zhiying Yue, Stefan Siwko, Ning Wang, Lujian Liao, Mingyao Liu, Jian Luo

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From Guidelines to Action: Tackling Risk Factors for Surgical Site Infections by Caterina Elisabetta Rizzo, Roberto Venuto, Paola Tripodi, Linda Bartucciotto, Elvira Ventura Spagnolo, Antonio Nirta, Giovanni Genovese, Isabella La Spina, Sabrina Sortino, Alessandro Nicita, Francesco Loddo, Bruno Romeo, Raffaele Squeri, Cristina Genovese

“…<b>Background/Objectives:</b> Surgical site infections are a serious public health concern, representing a significant burden on healthcare systems and society. …”
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Circulating CD3+CD8+ T Lymphocytes as Indicators of Disease Status in Patients With Early Breast Cancer by Han‐Kun Chen, Yi‐Ling Chen, Wei‐Pang Chung, Zhu‐Jun Loh, Kuo‐Ting Lee, Hui‐Ping Hsu

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Sedation/Analgesia Administration Practice Varies according to Endoscopy Facility (Hospital- or Office-Based) Setting: Results from a Nationwide Survey in Greece by Georgios Tziatzios, Dimitrios N. Samonakis, Theocharis Tsionis, Spyridon Goulas, Dimitrios Christodoulou, Konstantinos Triantafyllou

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The members of zinc finger-homeodomain (ZF-HD) transcription factors are associated with abiotic stresses in soybean: insights from genomics and expression analysis by Hafiz Muhammad Rizwan, Jiayi He, Muhammad Nawaz, Keyu Lu, Mingfu Wang

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Metabolomic Links between Sugar-Sweetened Beverage Intake and Obesity by Bingjie Zhou, Reiko Ichikawa, Laurence D. Parnell, Sabrina E. Noel, Xiyuan Zhang, Shilpa N. Bhupathiraju, Caren E. Smith, Katherine L. Tucker, Jose M. Ordovas, Chao-Qiang Lai

“…We examined the association of plasma metabolomic profiles with SSB intake and obesity risk in 781 participants, aged 45–75 y, in the Boston Puerto Rican Health Study (BPRHS) using generalized linear models, controlling for potential confounding factors. …”
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Prevalence and clinical implications of the rare arc of Bühler using computed tomography angiography and digital subtraction angiography: a systematic review and meta-analysis by Gaowu Yan, Gaowu Yan, Yong Li, Suyu He, Hongwei Li, Morgan A. McClure, Qiang Li, Jifang Yang, Hu Wang, Linwei Zhao, Xiaoping Fan, Jing Yan, Siyi Wu, Wenwen Guo

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Case report: Pseudoprogression mimicking neoplastic recurrence three months after completion of proton beam therapy for an IDH-mutant astrocytoma CNS WHO grade 3 by Liv Cathrine Heggebø, Liv Cathrine Heggebø, Ida Maria Henriksen Borgen, Ida Maria Henriksen Borgen, Hanne Blakstad, Hanne Blakstad, Cathrine Saxhaug, Pål André Rønning, Pitt Frederik Niehusmann, Katja Werlenius, Malin Blomstrand, Malin Blomstrand, Petter Brandal, Petter Brandal

“…BackgroundRadiation-induced changes following proton beam therapy in isocitrate dehydrogenase (IDH)-mutated diffuse central nervous system (CNS) World Health Organization (WHO) grade 2 and 3 gliomas are not well characterized. …”
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A bibliometric analysis of optic atrophy from 2003 to 2023: research trends and hot spots by Liyuan Wang, Liyuan Wang, Liyuan Wang, Tianyang Yu, Tianyang Yu, Runze Wang, Lijuan Fu, Lijuan Fu, Feixue Dong, Feixue Dong, Shuang Zhao, Shuang Zhao, He Sun, He Sun, Yang Gao

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