Opioid agonist therapy discontinuation in British Columbia: a cross-sectional study of people who access harm reduction services by Michael Otterstatter, Jane A Buxton, Kristi Papamihali, Brittany Graham, Lisa Liu, Kimia Ziafat, Bradley Kievit

“…Objectives This study evaluates the prevalence and correlates of opioid agonist therapy (OAT) discontinuation across British Columbia (BC), using a sample of individuals who used substances and accessed harm reduction sites.Design This study uses data from the 2019 cross-sectional Harm Reduction Client Survey (HRCS).Setting The 2019 survey was administered from October to December at 22 harm reduction supply distribution sites across the 5 Regional Health Authorities of BC.Participants The 2019 HRCS was administered among individuals who used illicit substances in the past 6 months and were aged 19 years and above.Primary and secondary outcome measures The primary outcome was defined as self-reported discontinuation of OAT in the past 6 months. …”
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Diagnostic Challenges in Uncommon Firearm Injury Cases: A Multidisciplinary Approach by Andrea Vittorio Maria Failla, Gabriele Licciardello, Giuseppe Cocimano, Lucio Di Mauro, Mario Chisari, Francesco Sessa, Monica Salerno, Massimiliano Esposito

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Emotions and Behaviors of Children Aged 0-6 during the Period of Epidemic Prevention at Home by Xuechang HE, Hui OUYANG, Hanzhang GUO, Zhuoming CHEN, Longbin SHEN, Jianlin OU

“…Objective:To understand the emotion, behavior and the influencing factors at home epidemic prevention during the epidemic of Corona Virus Disease 2019(COVID-19) in children aged 0-6, and to provide a theoretical basis for the health promotion and family intervention education of that age in similar situations.Methods:On February 24, 2020, a convenient sampling method was used to invite guardians of children aged 0-6 to conduct a online questionnaire survey one month after the government adopted a large-scale outbreak control strategy.Results:The effective rate of the questionnaire was 98.79%(163/165), mainly from Guangdong Province (75.46%). …”
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Analysing DNA methylation and transcriptomic signatures to predict prostate cancer recurrence risk by Fahad M. Aldakheel, Hadeel Alnajran, Shatha A. Alduraywish, Ayesha Mateen, Mohammed S. Alqahtani, Rabbani Syed

“…Abstract Prostate cancer (PCa) remains a significant global health challenge, with approximately 1.6 million new cases and 366,000 deaths annually. …”
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Ocular biometric parameters in Chinese preschool children and physiological axial length growth prediction using machine learning algorithms: a retrospective cross-sectional study by Yan Li, Kai Wang, Tao Tang, Heng Zhao, Jingwei Zhou, Mingwei Zhao, Duanke Liu, Xuewei Li, Xiaoqing Shi, Jiahui Ma, Chenxu Zhao

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State Estimation in Power Systems Under Random Data Attack Using Correlation Matching, Semidefinite Relaxation, and Truncated Eigenvalue Decomposition by Bamrung Tausiesakul, Krissada Asavaskulkiet, Chuttchaval Jeraputra, Ittiphong Leevongwat, Thamvarit Singhavilai, Supun Tiptipakorn

“…To monitor the operational health of the smart grids, power system state estimation is a crucial task and becomes challenging when a false data injection occurs. …”
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SUCCESSFUL REGISTRATION OF DOMESTIC BIOANALOGUE OF BEVACIZUMAB – NEW OPPORTUNITIES FOR EFFECTIVE TREA TMENT OF PATIENTS WITH NON-SQUAMOUS CELL NON-SMALL CELL LUNG CANCER by S. V. Orlov, S. N. Fogt, M. S. Shustova

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A MALDI-ToF mass spectrometry database for identification and classification of highly pathogenic bacteria by Peter Lasch, Wolfgang Beyer, Alejandra Bosch, Rainer Borriss, Michal Drevinek, Susann Dupke, Monika Ehling-Schulz, Xuewen Gao, Roland Grunow, Daniela Jacob, Silke R. Klee, Armand Paauw, Jörg Rau, Andy Schneider, Holger C. Scholz, Maren Stämmler, Le Thi Thanh Tam, Herbert Tomaso, Guido Werner, Joerg Doellinger

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Contamination profile of heavy metals in marine fish and shellfish by M.A. Salam, S.C. Paul, S.N.B.M. Noor, S.A. Siddiqua, T.D. Aka, R. Wahab, E.R. Aweng

“…In this study, accumulation of heavy metals (zinc, copper, iron, cadmium and lead) in various organs of four commonly consumed fish (<em>Euthynnus affinis</em>, <em>Pampus argenteus, </em><em>Descapterus macrosoma, </em>and<em> Leiognathus daura</em>), prawn (<em>Fenneropenaeus indicus) and</em> crab <em>(Portunus pelagicus)</em> of Tok Bali Port, Kelantan, Malaysia were determined<em>. </em>Health risk was assessed using estimated daily intake and target hazard quotients<em>. …”
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Lymphatic-derived oxysterols promote anti-tumor immunity and response to immunotherapy in melanoma by Mengzhu Sun, Laure Garnier, Romane Chevalier, Martin Roumain, Chen Wang, Julien Angelillo, Julien Montorfani, Robert Pick, Dale Brighouse, Nadine Fournier, David Tarussio, Stéphanie Tissot, Jean-Marc Lobaccaro, Tatiana V. Petrova, Camilla Jandus, Daniel E. Speiser, Manfred Kopf, Caroline Pot, Christoph Scheiermann, Krisztian Homicsko, Giulio G. Muccioli, Abhishek D. Garg, Stéphanie Hugues

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Structure-based identification of HNF4α agonists: Rosmarinic acid as a promising candidate for NAFLD treatment by Xi Chen, Xinqi Zhu, Gang Wu, Xiaobo Wang, Yu Zhang, Nan Jiang

“…The prevention and treatment of metabolic disorders, such as non-alcoholic fatty liver disease (NAFLD), have emerged as critical global health challenges. Current lipid-lowering pharmacotherapies are associated with side effects, including hepatotoxicity, rhabdomyolysis, and decreased erythrocyte counts, underscoring the urgent need for safer therapeutic alternatives. …”
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Computer-Aided Supporting Models of Customized Crack Propagation Sensors for Analysis and Prototyping by Paulina Kurnyta-Mazurek, Rafał Wrąbel, Artur Kurnyta

“…The range of sensor technologies for structural health monitoring (SHM) systems is expanding as the need for ongoing structural monitoring increases. …”
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Patterns of pharmacological treatment in patients with atrial fibrillation: an analysis from the prospective GLORIA-AF Registry Phase III by Bernadette Corica, Giulio Francesco Romiti, Giuseppe Boriani, Brian Olshansky, Tze-Fan Chao, Menno V. Huisman, Marco Proietti, Gregory Y. H. Lip, on behalf of the GLORIA-AF Investigators

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Application of RhBMP-2 in Percutaneous Endoscopic Posterior Lumbar Interbody Fusion by Yunsheng Chen, Canhua Xu, Yaohong Wu, Jiangyou Shi, Rongchun Chen

“…The cognitive function, social function, physiological function, and mental health were evidently improved in both groups 12 months post-operation and were significantly higher in the RhBMP-2 group than in the control (P < 0.05). …”
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Automated on-site broiler live weight estimation through YOLO-based segmentation by Mahmoud Y. Shams, Wael M. Elmessery, Awad Ali Tayoush Oraiath, Ahmed Elbeltagi, Ali Salem, Pankaj Kumar, Tamer M. El-Messery, Tarek Abd El-Hafeez, Mohamed F. Abdelshafie, Gomaa G. Abd El-Wahhab, Ibrahim S. El-Soaly, Abdallah Elshawadfy Elwakeel

“…Broiler weighing is essential in poultry production for growth monitoring, feed management, health detection, and meeting market requirements. …”
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Metabolic and inflammatory status in prepuberty and early adulthood for individuals with a history of extrauterine growth restriction: a cohort study by Laura Palomino-Fernández, Inmaculada Velasco, Belén Pastor-Villaescusa, Katherine Flores-Rojas, María de la Cruz Rico, Juan Roa, Ángel Gil, Mercedes Gil-Campos

“…The aim of this study was to evaluate possible alterations resulting from impaired growth during early childhood and their impact on young adult health. Methods This is a longitudinal, descriptive and analytical study of a cohort with a history of EUGR recruited at prepubertal age and followed up for 10 years until the end of puberty. …”
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Exploring Web-Based Support for Suicidal Ideation in the Scottish Population: Usability Study by Heather McClelland, Rory C O'Connor, Laura Gibson, Donald J MacIntyre

“… BackgroundSuicide is a global health concern. In the United Kingdom, Scotland has the highest suicide rate. …”
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Comparative Analysis of Adverse Drug Reactions Associated with Fluoroquinolones and Other Antibiotics: A Retrospective Pharmacovigilance Study by Alshareef H, Alenzi KA, Albalawi BR, Alanazi RM, Albalawi NS, Alasoufi WS, Alqifari S, Ahmed R, Ali MAS

“…Hanan Alshareef,1 Khalidah A Alenzi,2 Budor R Albalawi,3 Rinas M Alanazi,3 Nawal S Albalawi,3 Wedad Saleem Alasoufi,3 Saleh Alqifari,1 Rehab Ahmed,4 Mostafa AS Ali1 1Pharmacy Practice Department, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia; 2Transformation and Business Development, Tabuk Health Cluster, Tabuk, Saudi Arabia; 3Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia; 4Division of Microbiology, Immunology and Biotechnology, Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi ArabiaCorrespondence: Hanan Alshareef, Pharmacy Practice Department, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia, Email halsharef@ut.edu.saBackground: Fluoroquinolones (FQs) are among the most popular antimicrobials that are highly effective against various infections. …”
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Evidences of +896 A/G TLR4 Polymorphism as an Indicative of Prevalence of Complications in T2DM Patients by Carmela Rita Balistreri, Anna Rita Bonfigli, Massimo Boemi, Fabiola Olivieri, Antonio Ceriello, Stefano Genovese, Claudio Franceschi, Liana Spazzafumo, Paolo Fabietti, Giuseppina Candore, Calogero Caruso, Domenico Lio, Roberto Testa

“…T2DM is today considered as world-wide health problem, with complications responsible of an enhanced mortality and morbidity. …”
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Sidewalk thermal comfort in street canyon and role of pavements under perpendicular sun rays during summer by D. Jareemit, M. Srivanit

“…This finding carries significant importance in densely populated areas with limited natural shade, where even slight improvements in thermal comfort can have a positive effect on public health and well-being.CONCLUSION: Albedo reduction alone may not significantly enhance outdoor comfort within the street canyons. …”
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