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49241
GPX3 as a Novel and Potential Therapeutic Target in the Shared Molecular Mechanisms of Traumatic Brain Injury and Parkinson’s Disease
Published 2025-02-01“…Yue Wang,1– 5 Jiang Fang,1– 5 Qiang Yuan,1– 5 Jian Yu,1– 5 Jin Hu1– 5 1Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200040, People’s Republic of China; 2National Center for Neurological Disorders, Huashan Hospital, Fudan University, Shanghai, 200040, People’s Republic of China; 3Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Huashan Hospital, Fudan University, Shanghai, 200040, People’s Republic of China; 4Neurosurgical Institute of Fudan University, Huashan Hospital, Fudan University, Shanghai, 200040, People’s Republic of China; 5Shanghai Clinical Medical Center of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200040, People’s Republic of ChinaCorrespondence: Jian Yu; Jin Hu, Department of Neurosurgery, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, People’s Republic of China, Tel +86 21 52889999, Email hujin@fudan.edu.cn; lance2000@hotmail.comBackground: Traumatic brain injury (TBI) is a prevalent neurological disorder associated with significant public health burdens and long-term risks, including neurodegenerative diseases such as Parkinson’s disease (PD). …”
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49242
Development and validation of an explainable machine learning prediction model of hemorrhagic transformation after intravenous thrombolysis in stroke
Published 2025-01-01“…The explainable analysis of the RF-based ML model indicated that the National Institute of Health Stroke Scale (NIHSS) score, age, platelet count, and atrial fibrillation were the primary determinants for HT following IV-tPA thrombolysis.ConclusionThe RF-based explainable ML model demonstrated promising predictive ability for estimating the risk of HT after IV-tPA thrombolysis and may have the potential to assist the clinical decision-making in emergency settings.…”
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49244
Metatranscriptomes-based sequence similarity networks uncover genetic signatures within parasitic freshwater microbial eukaryotes
Published 2025-02-01“…All these protein families could offer valuable insights for developing antiparasitic treatments in health and economic contexts. Video Abstract…”
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49245
Efficacy of Ivermectin, Liquid Paraffin, and Carbaryl against Mange of Farmed Rabbits in Central Kenya
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49246
Spatiotemporal Characteristics and Influential Factors of Electronic Cigarette Web-Based Attention in Mainland China: Time Series Observational Study
Published 2025-02-01“…ConclusionsWith the increasing popularity of web-based searches for e-cigarettes, a targeted e-cigarette health education program for individuals in the northwest, males, rural populations, high school and above educated individuals, and high-income groups is warranted.…”
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49247
Short-Term Clinical Outcomes After Anterior Cruciate Ligament Reconstruction In Adolescents During The COVID-19 Pandemic
Published 2022-06-01“…# Background/Purpose The COVID-19 pandemic has impacted adolescents across multiple areas of health. While many factors influence outcomes following anterior cruciate ligament reconstruction (ACLR), the impact of the COVID-19 pandemic on early patient outcomes after ACLR is currently unknown in an adolescent population. …”
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49248
Antibiotic use in different hospital administrative categories: an overview of 10 years of a statewide surveillance program in Brazil
Published 2025-01-01“… Abstract Objective: The present study aimed to describe ICU antibiotic use based on data reported from 2009 to 2018 to the Nosocomial Surveillance System (NSS) of the State Health Department in the State of Sao Paulo, Brazil. …”
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49249
Microbial communities associated with the skin, gill, and gut of large yellow croaker (Larimichthys crocea)
Published 2025-01-01“…This study provides new insights into the structure, environmental response pattern, and relationship with host health of microbiota associated with the mucosal tissues of large yellow croaker.…”
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49250
Early warning systems (EWSs) for chikungunya, dengue, malaria, yellow fever, and Zika outbreaks: What is the evidence? A scoping review.
Published 2021-09-01“…<h4>Methods</h4>Data were extracted from Cochrane Database of Systematic Reviews (CDSR), Google Scholar, Latin American and Caribbean Health Sciences Literature (LILACS), PubMed, Web of Science, and WHO Library Database (WHOLIS) databases until August 2019. …”
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Gender Disparities in Medical and Dental Admissions: Students' Perspectives on Barriers
Published 2025-02-01“…Among the surveyed students, 37.5% (n=15) reported encountering barriers in pursuing health sciences. The primary obstacles identified were safety concerns and transportation issues at academic institutions (47.5%, n=19), followed by cultural norms and social pressures (20%, n=8), and a lack of female role models in college (12.5%, n=5). …”
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49254
Polyphenolic Compounds in Fabaceous Plants with Antidiabetic Potential
Published 2025-01-01“…Current treatments for diabetes include oral hypoglycemic drugs, which can lead to adverse effects and health complications. Other natural alternatives for DM treatment have been studied as adjunct therapies that could reduce or eliminate the need for antidiabetic medications. …”
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The Stress and Adversity Inventory for Adults (Adult STRAIN) in Korean: Initial Validation and Associations with Psychiatric Disorders
Published 2024-12-01“…Background/Objectives: Stressors occurring across the life course are considered to have a cumulative impact on health, but there is no instrument for assessing lifetime stressor exposure in Korea. …”
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Biochemical Composition Variation among Southern Ethiopian Arabica Coffee (Coffea arabica L.) Genotypes
Published 2022-01-01“…Coffee (Coffea arabica L.) provides several health benefits to users due to its strong medicinal and nutritional properties and caloric value. …”
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Effective treatment of severe acute pancreatitis and COVID-19 pneumonia with tocilizumab
Published 2020-09-01“…On 11th March 2020 COVID-19 was declared a pandemic by the World Health Organisation [2]. The most common symptoms are fever, cough, shortness of breath, fatigue, myalgia, and loss of smell and taste [3], but gastrointestinal symptoms like vomiting, diarrhoea, and abdominal pain are also reported [4, 5]. …”
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49259
Mixed pastures and biological efficiency in buffalo production systems: determinants for a sustainable livestock
Published 2023-11-01“…If these recommendations are met, production with B. bubalis would offer beneficial ecosystem services that would make the buffalo system a safer, more sustainable and resilient supplier of animal protein, since farms that operate under biological diversification criteria are more resistant to climate change, improve soil health, increase animal productivity and make efficient use of nutrients; however, each system is unique and its dynamism among components varies according to the yield goal sought by the producer according to local conditions. …”
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Resurgence of common respiratory viruses and mycoplasma pneumoniae after ending the zero-COVID policy in Shanghai
Published 2025-01-01“…Our finding highlights the need for public health interventions to prepare for the respiratory pathogen outbreaks in the post-COVID-19 era.…”
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