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49181
Identifying Complex Scheduling Patterns Among Patients With Cancer With Transportation and Housing Needs: Feasibility Pilot Study
Published 2025-01-01“…Identifying patients who might benefit from scheduling and social support from community health workers or patient navigators is largely determined on a case-by-case basis and is resource intensive. …”
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49182
Diagnosis and treatment of thyroblastoma: a case report and review of literature
Published 2025-02-01“…Background and objectiveThe diagnosis of thyroblastoma initially identified as a thyroid malignant teratoma was subsequently classified as a distinct entity by the World Health Organization (WHO) in 2022. This classification was based on the observation that the tumor presents with independent primitive multilineage elements and is frequently associated with DICER1 hotspot mutations.The objective of this study was to explore and investigate the clinicopathologic characteristics, molecular features and treatment strategies of patients with thyroblastoma, followed by a review of the previous relevant literature.MethodsThe clinical manifestations, pathological characteristics, molecular features and treatment strategies of the initial case of thyroblastoma pathologically confirmed in China were analyzed.ResultsThe tumor was revealed to have high invasive potential, rapid disease progression, and primitive multilineage elements of pathology, including immature thyroid epithelium, spindled mesenchymal proliferations, and neuroepithelial blastema. …”
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49183
In Vitro Mechanism of Action of Acanthospermum hispidum in Trypanosoma brucei
Published 2022-01-01“…African trypanosomiasis is a major neglected tropical disease with significant health and economic concerns in sub-Saharan Africa. …”
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49187
Geochemistry and mineralogy of Cobalt in mine wastes: examples from Cobalt, Canada and Cornwall, England
Published 2025-02-01“…Mine wastes can pose environmental and human health risks, especially when they contain high concentrations of potentially toxic metal(loid)s. …”
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49189
Carbapenem resistance in gram-negative pathogens in an Iranian hospital: high prevalence of OXA-type carbapenemase genes
Published 2025-01-01“…Background The widespread dissemination of carbapenem-resistant gram-negative bacteria poses a significant threat to global public health. Purpose This study aimed to investigate the prevalence of carbapenem resistance in gram-negative bacteria isolated from patients at the Children's Medical Center Hospital, Tehran, Iran, to understand the molecular mechanisms underlying this resistance. …”
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49192
Patient Perception of Ideal Body Weight and the Effect of Body Mass Index
Published 2014-01-01“…Despite much effort, obesity remains a significant public health problem. One of the main contributing factors is patients’ perception of their target ideal body weight. …”
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49193
Home Medication Review among Patients with Chronic Diseases in Rural Villages of Pahang, Malaysia: A Case Report
Published 2025-01-01“…They also advocate for integrating technology, enhancing patient education, and addressing social determinants to improve medication understanding and overall health outcomes in underserved populations. …”
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49194
Orange sweet potato flour production: Comparative effects on ultrasound, drying, storage, and techno-economic assessment
Published 2025-06-01“…Sweet potatoes (Ipomoea batatas) are recognized for their nutritional value and rich content of bioactive compounds, which contribute to their health benefits. Despite these advantages, the limited diversity of products derived from sweet potatoes has hindered their broader industrial application. …”
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49195
Contribution of Aerosol Species to the 2019 Smoke Episodes over the East Coast of Peninsular Malaysia
Published 2022-05-01“…Abstract Large-scale biomass burning (BB) emits large amounts of aerosols that lead to transboundary smoke events and adversely impacts human health, whilst causing societal and environmental issues. …”
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49196
Phage therapy in the management of respiratory and pulmonary infections: a systematic review
Published 2025-01-01“…Background: Lower respiratory tract infections (LRTIs) pose a significant threat to global health, causing more than 2 million deaths worldwide. …”
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Impact of Global Mean Normalization on Regional Glucose Metabolism in the Human Brain
Published 2018-01-01“…These results caution the use of GMN upon PET-measured CMRglc data in health and disease.…”
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Serum vitamin C levels and their correlation with chronic kidney disease in adults: a nationwide study
Published 2024-12-01“…Given the recognized antioxidant properties of vitamin C, our study aimed to explore the correlation between CKD and serum vitamin C levels.Methods Data were gathered from the 2017–2018 National Health and Nutrition Examination Survey. Participants below 18 years of age, pregnant individuals, those lacking essential data for CKD diagnosis, or individuals with incomplete serum vitamin C data were excluded. …”
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49199
Cyclic Peptides as Protein Kinase Modulators and Their Involvement in the Treatment of Diverse Human Diseases
Published 2024-12-01“…The cyclicity of cyclic peptides (CPs) can mimic the interactions between PKs and natural substrates, influencing the enzyme activity essential in health and disease physiology. Our review summarized that interference in the signal transduction mechanism of the PKs by CPs implies the inhibition of substrate phosphorylation at the level of the active site, similar to anti-neoplastic drugs. …”
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Wearable electrodriven switch actively delivers macromolecular drugs to fundus in non-invasive and controllable manners
Published 2025-01-01“…Moreover, WES-enhanced anti-VEGF administration resulted in an 86% inhibition of choroidal neovascularization, and anti-PDL1 delivery inhibited choroidal melanoma growth more effectively than intravenous injections, with no adverse effects on ocular health. These findings suggest that WES holds transformative potential for the non-invasive treatment of chronic fundus diseases.…”
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