Efficient Dual Cas9 Nickase Correction of a Prevalent Pathogenic LAMB3 Variant for Junctional Epidermolysis Bullosa by Alex du Rand, John Hunt, Daniel Verdon, Ben Buttle, P. Rod Dunbar, Diana Purvis, Vaughan Feisst, Hilary Sheppard

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Observation of a case of mass diarrhea and related integrated traditional Chinese and western medicine nursing (1起群体性腹泻的病情观察及中西医护理体会) by LI Yuncui (李运翠), TANG Ling (唐玲), LI Ye (李野), WANG Liangmin (王梁敏), ZHAO Dandan (赵丹丹), QI Wenjing (綦文婧)

“…Key issues of nursing interventions for diarrhea included illness condition observation, auricular point pressing therapy, moxibustion; psychological care; diet guidance; disinfection and protection, health education and extended care. The integrated traditional Chinese and western medicine nursing is effective to relieve the diarrhea symptoms, reduce the pain degree and improve the rehabilitation of patients. …”
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N6-methyladenosine regulates metabolic remodeling in kidney aging through transcriptional regulator GLIS1 by Li Xu, Shuo Chen, Qiuling Fan, Yonghong Zhu, Hang Mei, Jiao Wang, Hongyuan Yu, Ying Chen, Fan Liu

“…Abstract Background Age-related kidney impairment, characterized by tubular epithelial cell senescence and renal fibrosis, poses a significant global public health threat. Although N6-methyladenosine (m6A) methylation is implicated in various pathological processes, its regulatory mechanism in kidney aging remains unclear. …”
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Anti-Tissue-Transglutaminase IgA Antibodies Presence Determination Using Electrochemical Square Wave Voltammetry and Modified Electrodes Based on Polypyrrole and Quantum Dots by Angela Gabriela Pãun, Simona Popescu, Alisa Ioana Ungureanu, Roxana Trusca, Alina Popp, Cristina Dumitriu, George-Octavian Buica

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Evaluating the Accumulation of Grain Mercury in Engineered Rice Lines Containing <i>merA</i> and <i>merB</i> Genes Under an Organic Mercury-Enriched Condition by Deyao Meng, Zhaoze Song, Jinyuan Liu, Liyang Ji, Chen Chen, Changhu Wang

“…Excessive soil mercury not only hampers rice’s growth and development but also leads to a substantial accumulation in grains, posing a significant threat to human health. To mitigate the issue, low-mercury germplasms in rice were developed by expressing bacterial <i>merA</i> and <i>merB</i> genes, which convert mercury to less toxic forms from its most hazardous organic form: methylmercury. …”
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Matched Unrelated Donor Hematopoietic Cell Transplantation: Increased Usage and Improvements in Clinical Outcomes in Canada by Matthew D. Seftel, Grace Musto, David Allan, Oliver Bucher, Kevin Hay, Ivan Pasic, Tony Truong, Kristjan Paulson

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Are Bentong ginger (Zingiber officinale) biosynthesized silver nanoparticles safe and effective? An optimization, characterization, and toxicity evaluation study by Nor-Azmiraah Abd Jabar, Mahmud Ab Rashid Nor-Khaizura, Siti Izera Ismail, Yuet Ying Loo, Kah Hui Chong, Kousalya Padmanabhan, Shan Jiang

“…Although silver nanoparticles possess antimicrobial ability, the potential toxicity to human health and environmental concerns must be considered before deploying into food industries. …”
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Prevalence and Associated Factors of Intestinal Parasitic Infections among Food Handlers in Mettu Town, Southwest Ethiopia by Solomon Yeshanew, Melaku Tadege, Abdulhakim Abamecha

“…Mass drug administration for all food handlers working in food establishment areas of the town coupled with health education and training should be initiated urgently.…”
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Antiviral Activity of Pistacia atlantica subsp. Kurdica Extract Against Herpes Simplex Virus Type 1 by Shahin Gavanji, Hojjat Baghshahi, Azizollah Bakhtari, Ali Mohamadi, Zahra Hamami Chamgordani, Mojtaba Khandan, Javaher Sinaei

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Regional differences in triage decisions affect hospital mortality among frail COVID-19 patients in the COvid MEdicaTion study by Julia Minnema, Roos Sablerolles, Janneke van Kempen, Hugo van der Kuy, Harmke Polinder-Bos, Bob van de Loo, Jorie Versmissen, Miriam L. Haaksma, Melvin Lafeber, Miriam C. Faes, on behalf of the COMET research team^

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The book policy in a democratic society: the case of Estonia by Mare Lott, Aile Möldre

“…In contemporary Estonia, the limitations to freedom of expression entail, like in pre-war Estonia, the protection of public order and morals, but also the rights, freedom, health, honor, and good name of other people. The criminal code prohibits the inciting of national, racial, religious, or political hatred, or propagating violence and disseminating pornography among minors. …”
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Adaptation Studies of the Aggression and Victimization Scales for Elementary School Children by Arzu KURNAZ, Emine Gül KAPÇI

“…As relational aggression andvictimization were found to be related with several mental health problems among school children, both scales could beutilized in the evaluation of overt and relational dimensions of both agression and victimization among Turkish elementaryschool children…”
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A Comparative Study of the Metabolic and Skeletal Response of C57BL/6J and C57BL/6N Mice in a Diet-Induced Model of Type 2 Diabetes by Elizabeth Rendina-Ruedy, Kelsey D. Hembree, Angela Sasaki, McKale R. Davis, Stan A. Lightfoot, Stephen L. Clarke, Edralin A. Lucas, Brenda J. Smith

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Effectiveness of Fewer Falls, an online group-based self-management fall prevention programme for people with multiple sclerosis: protocol of a randomised controlled trial by Maria Flink, Charlotte Ytterberg, Kristina Gottberg, Marie Kierkegaard, Susanna Tuvemo Johnson, Elizabeth Walker Peterson, Ulrika Meijer, Johanna Bylinder

“…Secondary outcomes include injurious falls, falls control, fear of falling, falls self-efficacy, activity curtailment, perceived effect of MS, self-rated health and cost-effectiveness.Ethics and dissemination Ethical approval has been obtained from the Swedish Ethical Review Authority (registration numbers 2022-06667-01 and 2023-07723-02). …”
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Microstructural lateralization of thalamocortical connections in individuals with a history of reading difficulties by Yueye Zhao, Jianyi Liu, Xue'er Ma, Zi-Gang Huang, Jingjing Zhao

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Phytochemicals for mitigating the COVID-19 crisis: evidence from pre-clinical and clinical studies by Atri Das, Swarnali Khan, Syamal Roy, Shantanabha Das

“…The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in December 2019 quickly escalated to pandemic levels and had a severe impact on public health. There are 761 million confirmed coronavirus disease 2019 (COVID-19) cases, with over 6.88 million deaths worldwide till March 2023. …”
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Knowledge, attitudes and practices of healthcare professionals in the management of patients with hypertension and concurrent bronchial asthma: a cross-sectional study in the Yello... by Yang Yang, Wenwen Xu, Fei Yu, Xiaohong Yan, Xingbin Ma, Jinxiang Gao

“…The reporting of this study followed the Strengthening the Reporting of Observational Studies in Epidemiology checklist.Setting From 30 March to 15 April 2024 at 66 various level hospitals and community health service centres.Participants Physicians and nurses specialising in clinical internal medicine, each with over 2 years of practice and who provided informed consent.Primary and secondary outcome measures The demographic characteristics of the healthcare professionals and their KAP towards the Management of Patients with Hypertension and Concurrent Bronchial Asthma were collected using a self-administered questionnaire. …”
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Negative Emotions in Migraineurs Dreams: The Increased Prevalence of Oneiric Fear and Anguish, Unrelated to Mood Disorders by F. De Angeli, C. Lovati, L. Giani, C. Mariotti D'Alessandro, E. Raimondi, V. Scaglione, D. Castoldi, E. Capiluppi, C. Mariani

“…The Generalized Anxiety Disorder Questionnaire (GAD-7), and the Patient Health Questionnaire (PHQ-9) were administered to evaluate anxiety and depression. …”
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Antimicrobial effect of silver diamine fluoride (SDF) in arresting dentine caries of permanent teeth: A Systematic review [version 1; peer review: 2 approved] by Mamata Hebbal, Albandri Mohammed Alowid, Praveen Jodalli, Shahad Saad Alkait, Ghadeer Ghalab Almutairi, Fatimah Salim Almufarji

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Perancangan User Experience Aplikasi Info COVID-19 Menggunakan Metode Human Centered Design by Pradya Mutiarahma, Hanifah Muslimah Az-Zahra, Yusi Tyroni Mursityo

“…Many things have been done as a form of prevention, such as creating an application that provides health-related information, especially about COVID-19. …”
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