The BET inhibitor JQ1 targets fat metabolism and counteracts obesity by Claudia Fornelli, Alessia Sofia Cento, Lorenzo Nevi, Raffaella Mastrocola, Gustavo Ferreira Alves, Giuseppina Caretti, Massimo Collino, Fabio Penna

“…Introduction: Obesity, one of the most frequent health problems in the adult population, is a condition characterized by excessive white adipose tissue accumulation and accompanied by the increased risk to develop other disorders such as type II diabetes, cardiovascular disorders, physical disability, frailty and sarcopenia. …”
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Exploring the antibacterial and anti-biofilm activity of two Iranian medical-grade kinds of honey on multidrug-resistant Pseudomonas aeruginosa by Mustafa Riyadh Alshaybawee, Shahrzad Asgari, Paria Ghadersoltani, Ahmadreza Mehrabian, Parastoo Saniee

“…Based on the evaluation and compliance with the medical grade criteria including authenticity, health, qualities well botanical origin mentioned honey is classified in medical grade. …”
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Optimal dose and type of exercise improve walking velocity in adults with Parkinson’s disease: a systematic review and Bayesian network meta-analysis by Shaoqing Xie, Yuan Yuan, Junyu Wang, Ying Bai, Tao Wang, Bopeng Qiu, Yong Yang, Shu-Cheng Lin

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Refining α-synuclein seed amplification assays to distinguish Parkinson’s disease from multiple system atrophy by James A. Wiseman, Clinton P. Turner, Richard L. M. Faull, Glenda M. Halliday, Birger Victor Dieriks

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White Matter Biomarkers Associated with Motor Change in Individuals with Stroke: A Continuous Theta Burst Stimulation Study by K. P. Wadden, S. Peters, M. R. Borich, J. L. Neva, K. S. Hayward, C. S. Mang, N. J. Snow, K. E. Brown, T. S. Woodward, S. K. Meehan, L. A. Boyd

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Stress assessment instruments for hospitalized preterm newborns: scoping review by Mónica Costa, Maria Filomena Gaspar, Maria Alice Curado, Ana Brantes

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The Effects of Different Roasting Degrees on Antioxidant of Coffee From West Sumatra by Muhammad Isa Dwijatmoko, R. A. Fadri, S. Syahrul, M. Harni, Y. Muchrida

“…<p><span lang="EN-US">Coffee has several benefits for human health because it contains bioactive components and one of which is polyphenol components. …”
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Association of Intensive Endoscopic Burden with Esophageal Cancer Detection: A Nationwide Cohort Study by Yeunji Lee, Eunyoung Lee, Bumhee Park, Gil Ho Lee, Sun Gyo Lim, Sung Jae Shin, Choong-Kyun Noh, Kee Myung Lee

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Spatiotemporal occurrence, distribution, and risk of steroid hormones along the coast of Guangdong, China by Xing Zhao, Xing Zhao, Yunlin Jiang, Hanqiang Deng, Yao Lu, Suimin Li, Yuxia Jiang, Kaifeng Sun

“…Nevertheless, the consumption of seafood does not pose a significant health risk to humans. To the best of our knowledge, this is the first study to concurrently analyze androgens, glucocorticoids, progestins, and estrogens in water, sediment, and organisms from diverse marine environments.…”
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In vivo kinematic analysis of failure cases after nonanatomical anterior cruciate ligament reconstruction: a preliminary study by Tomofumi Kage, Shuji Taketomi, Tetsuya Tomita, Takaharu Yamazaki, Ryota Yamagami, Kenichi Kono, Kohei Kawaguchi, Ryo Murakami, Takahiro Arakawa, Takashi Kobayashi, Hiroshi Inui, Sakae Tanaka

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Clinical evidence based review and recommendations of aerosol generating medical procedures in otolaryngology – head and neck surgery during the COVID-19 pandemic by Andrew Thamboo, Jane Lea, Doron D. Sommer, Leigh Sowerby, Arman Abdalkhani, Christopher Diamond, Jennifer Ham, Austin Heffernan, M. Cai Long, Jobanjit Phulka, Yu Qi Wu, Phillip Yeung, Marc Lammers

“…Abstract Background Aerosol generating medical procedures (AGMPs) present risks to health care workers (HCW) due to airborne transmission of pathogens. …”
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Determination of genetic diversity in persimmon accessions using morphological and inter simple sequence repeat markers by Yazgan Tunç, Canan Aydınlıoğlu, Kadir Uğurtan Yılmaz, Ali Khadivi, Daya Shankar Mishra, El Hassan Sakar, Tomáš Vyhnánek

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The Prevalence and Diagnostic Ratio of Familial Hypercholesterolemia (FH) and Proportion of Acute Coronary Syndrome in Japanese FH Patients in a Healthcare Record Database Study by Tamio Teramoto, Tomohiro Sawa, Satoshi Iimuro, Hyoe Inomata, Takashi Koshimizu, Iori Sakakibara, Katsutoshi Hiramatsu

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Temporal Analysis of the Incidence, Mortality and Disability-Adjusted Life Years of Benign Gallbladder and Biliary Diseases in High-Income Nations, 1990–2019 by Dominic W. Proctor, BMBS, MSc, Richard Goodall, BSc, MBChB, MRCS, FHEA, Kim Borsky, MBBS, MMRCS, Justin D. Salciccioli, MBBS, MA, Dominic C. Marshall, MBBS, MRCP, BSc, Kumaran Shanmugarajah, MD, PhD, Joseph Shalhoub, BSc, MBBS, FHEA, PhD, DIC, MEd, FFSTEd, FRCS, FEBVS

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Astrocytic proteins involved in regulation of the extracellular environment are increased in the Alzheimer's disease middle temporal gyrus by Henry Liu, Adelie Y.S. Tan, Nasim F. Mehrabi, Clinton P. Turner, Maurice A. Curtis, Richard L.M. Faull, Mike Dragunow, Malvindar K. Singh-Bains, Amy M. Smith

“…Astrocytes perform important homeostatic functions including regulation of the extracellular microenvironment, critical for the health of all brain cells. We have investigated changes to key astrocyte proteins involved in the regulation of CNS extracellular environment in the human AD middle temporal gyrus (MTG): aquaporin-4 (AQP-4), glutamate transporter-1 (GLT-1) and inwardly-rectifying potassium channel 4.1 (Kir4.1). …”
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Cross-Cultural Validity, Reliability, and Psychometric Properties of the Persian Version of the Scales for Outcomes in Parkinson’s Disease-Psychosocial Questionnaire by Seyed-Mohammad Fereshtehnejad, Farzaneh Farhadi, Hasti Hadizadeh, Gholam Ali Shahidi, Ahmad Delbari, Johan Lökk

“…Eligible patients filled up a number of questionnaires including the Persian version of SCOPA-PS during the face-to-face interview session and clinical examination to measure disease severity, nonmotor psychiatric symptoms, and health-related quality of life (HRQoL). Results. The highest and lowest correlation coefficients of internal consistency were reported for item 7 on “asking for help” (r=0.765) and item 5 on “sexual problems” (r=0.553). …”
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Role of Dolutegravir/Lamivudine in the Management of Pregnant People Living with HIV-1: A Narrative Review by William R. Short, Parul Patel, Gustavo Verdier, Ana Puga, Vani Vannappagari, Annemiek de Ruiter, Bryn Jones

“…The use of DTG/3TC during pregnancy is anticipated to be comparably effective and well tolerated for both parental health and prevention of vertical transmission with fetal exposure to fewer antiretrovirals compared with 3- or 4-drug regimens. …”
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Physical activity behaviour up to 1 year post-rehabilitation among adults with physical disabilities and/or chronic diseases: results of the prospective cohort study ReSpAct by Lucas H V van der Woude, Rienk Dekker, Trynke Hoekstra, Leonie A Krops, Femke Hoekstra, Florentina J Hettinga, Pim Brandenbarg, Bregje L Seves

“…Physical activity was assessed with the adapted version of the Short Questionnaire to ASsess Health enhancing physical activity. Dose characteristics of physical activity were descriptively analysed. …”
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Hypertensive disorders of pregnancy affected thyroid hormone synthesis via endoplasmic reticulum stress in preterm infant rats by Maomao Sun, Congrong Wu, Jie Jiang, Yue He, Sha Zhu, Yonghui Yu

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Triatoma venosa and Panstrongylus geniculatus challenge the certification of interruption of vectorial Trypanosoma cruzi transmission by Rhodnius prolixus in eastern Colombia. by Omar Cantillo-Barraza, Lídia Gual-González, Natalia Velásquez-Ortiz, Manuel Alfonso Medina Camargo, Paola González, Lissa Cruz-Saavedra, Adriana Castillo, Sara Zuluaga, Giovanny Herrera, Hanson Cowan, Andrés Velez-Mira, Luz Helena Patiño, Juan David Ramírez, Omar Triana, Melissa S Nolan

“…T. cruzi transmission via intra-domestic Rhodnius prolixus was certified as interrupted by the Pan American Health Organization in Miraflores municipality (Boyacá, Colombia) in 2019. …”
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