Targeted gut microbiome therapy: Applications and prospects of probiotics, fecal microbiota transplantation and natural products in the management of type 2 diabetes by Luqi Qin, Bei Fan, Yixia Zhou, Jiahuan Zheng, Rao Diao, Fengzhong Wang, Jiameng Liu

“…Type 2 diabetes mellitus (T2DM) is considered as one of the most pressing public health challenges worldwide. Studies have shown significant differences in the gut microbiota between healthy individuals and T2DM patients, suggesting that gut microorganisms may play a key role in the onset and progression of T2DM. …”
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A novel agricultural drought index based on multi-source remote sensing data and interpretable machine learning by Hao Chen, Ni Yang, Xuanhua Song, Chunhua Lu, Menglan Lu, Tan Chen, Shulin Deng

“…Drought is a frequent, destructive, and complex natural hazard, and seriously threatens eco-environment, socio-economy, and the health of human. Previous studies suggested that integrated multi-source remote sensing drought indices have the potential to comprehensively monitor drought conditions, however most existing integrated drought indices still have several limitations. …”
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Estrogen-related receptor gamma is a regulator of mitochondrial, autophagy, and immediate-early gene programs in spiny projection neurons: Relevance for transcriptional changes in... by Stephanie N. Fox, Cody H. Savage, Narcy R. Amireddy, Laura J. McMeekin, David K. Crossman, Peter J. Detloff, Michelle Gray, Rita M. Cowell

“…Strategies are needed to counteract these processes to restore neuronal health and function in HD. Recent evidence indicates that the transcription factor estrogen-related receptor gamma (ERRγ/Esrrg) is required for normal expression of mitochondrial, synaptic, and autophagy genes in neurons. …”
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Racial and ethnic differences in fatal child abuse and neglect and the intersection of community poverty: U.S., 2003 to 2022 by Rebecca F. Wilson, Xin Yue, Karen E. Thomas, Krishna Kiran Kota, Carter J. Betz

“…., child abuse and neglect (CAN) is a significant public health problem. Poverty is a well-known correlate of CAN. …”
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Targeting early tau pathology: probiotic diet enhances cognitive function and reduces inflammation in a preclinical Alzheimer’s model by Cassandra M. Flynn, Tamunotonye Omoluabi, Alyssa M. Janes, Emma J. Rodgers, Sarah E. Torraville, Brenda L. Negandhi, Timothy E. Nobel, Shyamchand Mayengbam, Qi Yuan

“…Probiotic supplementation could offer a novel early intervention strategy for AD, highlighting the pivotal role of gut health in neurodegeneration.…”
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The expression landscape and clinical significance of methyltransferase-like 17 in human cancer and hepatocellular carcinoma: a pan-cancer analysis using multiple databases by Yezhou Ding, Mingyang Feng, Wanqing Chi, Xiaoyin Wang, Baoyan An, Kehui Liu, Shike Lou, Xiaolin Wang, Hui Wang

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Effect of Medication Management at Home via Pharmacist-Led Home Televisits: Protocol for a Cluster Randomized Controlled Trial by Sheikh Rubana Hossain, Akanksha N Samant, Briana C Balsamo, Chelsea E Hawley, Michael C Zanchelli, Carolyn Zhu, Maria D Venegas, Marina Robertson, Megan B McCullough, Judith L Beizer, Kenneth S Boockvar, Albert L Siu, Lauren R Moo, William W Hung

“…ResultsThis project has been peer-reviewed and selected for support by the Veterans Affairs (VA) Health Services Research Service. The pilot phase of the study was completed December 2021 with 20 veterans and was primarily informed by the Steinman model of the prescribing process adapted to include system- and provider-level factors. …”
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Evaluating implementation of a hospital‐based cancer registry to improve childhood cancer care in low‐ and middle‐income countries by Melissa R. Maas, Allison Yang, Michele A. Muir, James B. Collins IV, Courtney Canter, Gevorg Tamamyan, Inam Chitsike, Francine Kouya, Kim Hoa Nguyen, Alia Ahmad, Ana Patricia Alcasabas, Yi‐Jin Gao, Kimberly J. Johnson, Gia Ferrara, Nickhill Bhakta, Benyam Muluneh

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Comparison of Placental Doppler Ultrasound indices in Pregnant Women with Iron Deficiency Anemia, Minor Beta-Thalassemia and Healthy Pregnant in first half of pregnancy by Zahra Rahmani, Maryam Abdi Valikchali, Tahere Gelini Moghaddam, Shahabodin Gharahveysi

“…Background and purpose: Anemia during pregnancy is a public health issue, particularly in developing countries, and is linked to adverse pregnancy outcomes such as premature birth, low birth weight (LBW), and placental growth disorders (vascular changes and placental volume). …”
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FNDC5/irisin mitigates the cardiotoxic impacts of cancer chemotherapeutics by modulating ROS-dependent and -independent mechanisms by Manish Kumar, Abhishek Singh Sengar, Anushree Lye, Pranesh Kumar, Sukhes Mukherjee, Dinesh Kumar, Priyadip Das, Suvro Chatterjee, Adele Stewart, Biswanath Maity

“…Together our data underscore the importance of FNDC5/irisin in maintenance of cardiac health over the lifespan.…”
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Non-contact tracking of shoulder bones using ultrasound and stereophotogrammetry by Ahmed Sewify, Ahmed Sewify, Maxence Lavaill, Maxence Lavaill, Dermot O’Rourke, Dermot O’Rourke, Maria Antico, Maria Antico, Peter Pivonka, Peter Pivonka, Davide Fontanarosa, Davide Fontanarosa, Saulo Martelli, Saulo Martelli

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Hubungan Diare dengan Status Gizi Balita di Kelurahan Lubuk Buaya Kecamatan Koto Tangah Kota Padang by Alania Rosari, Eka Agustia Rini, Masrul Masrul

“…<br />Kata kunci: status gizi balita, diare<br />Abstract<br />Malnutrition in children is still a major health problem in the world. Data from WHO in 2010 showed 18% of children under five years old in developing countries are underweight. …”
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Exploring the genotypic potential of perilla (Perilla frutescens L.) for climate-resilient agriculture in the North Eastern Himalayas by Meraj Alam Ansari, Meraj Alam Ansari, Amit Kumar, T. P. Ahammed Shabeer, Alok Kumar, Subhra Saikat Roy, Subhra Saikat Roy, Majhrool Hak Ansari, Raghavendra Singh, Raghavendra Singh, Moirangthem Sangeeta, Jayanta Layek, Narendra Prakash, Vinay K. Mishra

“…Large-scale cultivation of perilla improves food security and offers numerous health benefits, including cardiovascular support and disease prevention, thereby enhancing human wellbeing. …”
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Electroacupuncture alleviates functional constipation by upregulating host-derived miR-205-5p to modulate gut microbiota and tryptophan metabolism by Lu Wang, Lu Wang, Menghan Xi, Menghan Xi, Wei Cao, Haiyan Qin, Di Qin, Shuai Chen, Siyuan Zhou, Yujun Hou, Ying Chen, Xianjun Xiao, Qianhua Zheng, Dehua Li, Ying Li

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Total flavonoids isolated from Eucommia ulmoides can alleviate bone loss and regulate intestinal microbiota in ovariectomized rats by Baocang Yin, Baocang Yin, Mingzhen Yang, Mingzhen Yang, Bowen Wang, Bowen Wang, Yun Zhang, Yun Zhang, Ningli Li, Ningli Li, Qin Li, Yingying Li, Cory J. Xian, Tiejun Li, Tiejun Li, Yuankun Zhai, Yuankun Zhai

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Delayed Graft Function in Kidney Transplants: Time Evolution, Role of Acute Rejection, Risk Factors, and Impact on Patient and Graft Outcome by Martin Chaumont, Judith Racapé, Nilufer Broeders, Fadoua El Mountahi, Annick Massart, Thomas Baudoux, Jean-Michel Hougardy, Dimitri Mikhalsky, Anwar Hamade, Alain Le Moine, Daniel Abramowicz, Pierre Vereerstraeten

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CDK9 Expression Shows Role as a Potential Prognostic Biomarker in Breast Cancer Patients Who Fail to Achieve Pathologic Complete Response after Neoadjuvant Chemotherapy by Ashley J. Schlafstein, Allison E. Withers, Soumon Rudra, Diana Danelia, Jeffrey M. Switchenko, Donna Mister, Saul Harari, Hui Zhang, Waaqo Daddacha, Shahrzad Ehdaivand, Xiaoxian Li, Mylin A. Torres, David S. Yu

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Effect of zinc added to a daily small-quantity lipid-based nutrient supplement on diarrhoea, malaria, fever and respiratory infections in young children in rural Burkina Faso: a cl... by Elizabeth Yakes Jimenez, Sonja Y Hess, Souheila Abbeddou, Kenneth H Brown, Jean-Bosco Ouedraogo, Jérôme W Somé, Zinéwendé P Ouédraogo, Rosemonde M Guissou, Stephen A Vosti

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Predictive value of the systemic immune–inflammation index for outcomes in large artery occlusion treated with mechanical thrombectomy—a single-center study by Ao Qian, Longyi Zheng, Hui He, Jia Duan, Shuang Tang, Wenli Xing

“…Multivariate analysis demonstrated that heightened SII was significantly related to HT (odds ratio [OR]: 1.061, 95% confidence interval [CI]: 1.035–1.086, p &lt; 0.001), MBE (OR: 1.074, 95% CI: 1.045–1.103, p &lt; 0.001), adverse function (OR: 1.061, 95% CI: 1.031–1.092, p &lt; 0.001), and mortality (OR: 1.044, 95% CI: 1.018–1.070, p = 0.001), after adjusting sex, age, Glasgow Coma Scale (GCS) score at admission, initial National Institutes of Health Stroke Scale (NIHSS) score, baseline Alberta Stroke Program Early Computed Tomography Score (ASPECTS), present HMCAS, occluded vessel region, collateral score and successful revascularization. …”
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Identification and functional analysis of hub genes involved in deoxynivalenol-induced enterotoxicity in porcine (Sus scrofa) by Jinhua He, Geng Zhao, Mingxia Chen, Ximing Ren, Peizhi Zhu, Zhizhong Liu, Jiayi Zhou, Hanwei Chen, Chuqiao Xiao, Xiang-Guang Li

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