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N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1
Published 2025-01-01Get full text
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Minimal disease activity and associated factors in patients with psoriatic arthritis: cross-sectional study from a single center
Published 2024-11-01“…Patients who met at least 5 of 7 criteria (tender joint count ≤ 1/68, swollen joint count ≤ 1/66, Psoriasis Area Severity Index [PASI] ≤ 1, Visual Analogue Scale [VAS] ≤ 15, patient global VAS ≤ 20, Health Assessment Questionnaire-Disability Index [HAQ-DI] ≤ 0.5, and enthesitis number ≤ 1) were considered to achieve MDA. …”
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Malaria prevalence, transmission potential and efficacy of artemisinin-based combination therapy in the Kenyan Central highlands: a zone previously characterized as malaria-free
Published 2025-01-01“…The malaria clinical study was an open label non-randomized clinical trial where the efficacy of one ACT drug, was evaluated in two health facilities. Microscopy was used at the facility while nested 18 s rRNA subunit gene PCR amplification and MSP-1 and MSP-2 family alleles genotyping was done in the laboratory. …”
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Targeted gut microbiome therapy: Applications and prospects of probiotics, fecal microbiota transplantation and natural products in the management of type 2 diabetes
Published 2025-03-01“…Type 2 diabetes mellitus (T2DM) is considered as one of the most pressing public health challenges worldwide. Studies have shown significant differences in the gut microbiota between healthy individuals and T2DM patients, suggesting that gut microorganisms may play a key role in the onset and progression of T2DM. …”
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A novel agricultural drought index based on multi-source remote sensing data and interpretable machine learning
Published 2025-03-01“…Drought is a frequent, destructive, and complex natural hazard, and seriously threatens eco-environment, socio-economy, and the health of human. Previous studies suggested that integrated multi-source remote sensing drought indices have the potential to comprehensively monitor drought conditions, however most existing integrated drought indices still have several limitations. …”
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Estrogen-related receptor gamma is a regulator of mitochondrial, autophagy, and immediate-early gene programs in spiny projection neurons: Relevance for transcriptional changes in...
Published 2025-03-01“…Strategies are needed to counteract these processes to restore neuronal health and function in HD. Recent evidence indicates that the transcription factor estrogen-related receptor gamma (ERRγ/Esrrg) is required for normal expression of mitochondrial, synaptic, and autophagy genes in neurons. …”
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Racial and ethnic differences in fatal child abuse and neglect and the intersection of community poverty: U.S., 2003 to 2022
Published 2025-04-01“…., child abuse and neglect (CAN) is a significant public health problem. Poverty is a well-known correlate of CAN. …”
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Targeting early tau pathology: probiotic diet enhances cognitive function and reduces inflammation in a preclinical Alzheimer’s model
Published 2025-01-01“…Probiotic supplementation could offer a novel early intervention strategy for AD, highlighting the pivotal role of gut health in neurodegeneration.…”
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Effect of Medication Management at Home via Pharmacist-Led Home Televisits: Protocol for a Cluster Randomized Controlled Trial
Published 2025-02-01“…ResultsThis project has been peer-reviewed and selected for support by the Veterans Affairs (VA) Health Services Research Service. The pilot phase of the study was completed December 2021 with 20 veterans and was primarily informed by the Steinman model of the prescribing process adapted to include system- and provider-level factors. …”
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FNDC5/irisin mitigates the cardiotoxic impacts of cancer chemotherapeutics by modulating ROS-dependent and -independent mechanisms
Published 2025-03-01“…Together our data underscore the importance of FNDC5/irisin in maintenance of cardiac health over the lifespan.…”
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Non-contact tracking of shoulder bones using ultrasound and stereophotogrammetry
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Hubungan Diare dengan Status Gizi Balita di Kelurahan Lubuk Buaya Kecamatan Koto Tangah Kota Padang
Published 2013-09-01“…<br />Kata kunci: status gizi balita, diare<br />Abstract<br />Malnutrition in children is still a major health problem in the world. Data from WHO in 2010 showed 18% of children under five years old in developing countries are underweight. …”
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Exploring the genotypic potential of perilla (Perilla frutescens L.) for climate-resilient agriculture in the North Eastern Himalayas
Published 2025-02-01“…Large-scale cultivation of perilla improves food security and offers numerous health benefits, including cardiovascular support and disease prevention, thereby enhancing human wellbeing. …”
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