Metabolic Context Regulates Distinct Hypothalamic Transcriptional Responses to Antiaging Interventions by Alexis M. Stranahan, Bronwen Martin, Wayne Chadwick, Sung-Soo Park, Liyun Wang, Kevin G. Becker, William H. WoodIII, Yongqing Zhang, Stuart Maudsley

Get full text

Exogenous selenium enhances cadmium stress tolerance by improving physiological characteristics of Artemisia argyi seedlings by Yaxin Yu, Yingbin Yang, Yu Guo, Meiqi Pan, Wenfang Hao

“…Abstract The contamination of Chinese medicinal materials with cadmium (Cd) is a pressing global issue that poses significant risks to human health. The beneficial effects of selenium (Se) have been established in improving plant growth and reducing Cd accumulation in plant under Cd stress. …”
Get full text

Less cytotoxic phthalocyanine derivative promotes in vitro wound healing compared to chlorhexidine by Caique Andrade Santos, Adriano de Souza Pessoa, Fabiano Vieira Vilhena, Rodrigo Cardoso de Oliveira, Paulo Sérgio da Silva Santos, Carla Andreotti Damante, Mariana Schutzer Ragghianti Zangrando

Get full text

Candidate Genes Associated with Delayed Neuropsychomotor Development and Seizures in a Patient with Ring Chromosome 20 by Thiago Corrêa, Amanda Cristina Venâncio, Marcial Francis Galera, Mariluce Riegel

Get full text

Contributions of Limb Joints to Energy Absorption during Landing in Cats by Xueqing Wu, Baoqing Pei, Yuyang Pei, Nan Wu, Kaiyuan Zhou, Yan Hao, Wei Wang

Get full text

Production of Nanofibers Composed of CuO for the Removal of Pb(II) from Aqueous Solutions by Amábile Giotto dos Santos, Thiago Rodrigues Martins, Satheesh Krishnamurthy, Daniel Assumpção Bertuol, Eduardo Hiromitsu Tanabe

“…Pollution by heavy metals such as lead is a major concern, since exposure to these metals can lead to various adverse health effects. In this work, nanofibers composed of CuO (CuONFs) were developed as a novel and promising material for Pb(II) adsorption. …”
Get full text

Is the Adventitial Vasa Vasorum in Vulnerable Carotid Plaques Increased or Decreased? by Wang Yixuan, Jin Lin, Chen Jianxiong, Yang Huixian, Shen Cuiqin, Xu Wenzhe, Shen Yuzhou, Huang Jun, Sun Liwan, Du Lianfang, Wang Bei, Li Fan, Li Zhaojun

Get full text

Structural, Optical, Antibacterial, and Anticancer Properties of Cerium Oxide Nanoparticles Prepared by Green Synthesis Using Morinda citrifolia Leaves Extract by Abozer Y. Elderdery, Badr Alzahrani, Abdulrahim A. Alabdulsalam, Siddiqa M. A. Hamza, Ahmed M. E. Elkhalifa, Abdulaziz H. Alhamidi, Fehaid Alanazi, A. Mohamedain, Suresh Kumar Subbiah, Pooi Ling Mok

Get full text

Monte Carlo Simulation to Evaluate Mould Growth in Walls: The Effect of Insulation, Orientation, and Finishing Coating by Ricardo M. S. F. Almeida, Eva Barreira

“…Mould growth can have severe consequences both on the health of occupants and on constructions’ durability. …”
Get full text

Emerging Norovirus GII.12 infection in 2010 in Northern Taiwan by Chi-Neu Tsai, Yu-Chung Chang, Hsun-Ching Chao, Yi-Hsiang Hsu, Yuan-Hung Wang, Shih-Yen Chen

“…Continued research is essential to unravel the intricate relationship between NoV genotypes and clinical outcomes, guiding public health interventions and therapeutic strategies.…”
Get full text

Clinical considerations on antimicrobial resistance potential of complex microbiological samples by Norbert Solymosi, Adrienn Gréta Tóth, Sára Ágnes Nagy, István Csabai, Csongor Feczkó, Tamás Reibling, Tibor Németh

“…Antimicrobial resistance (AMR) is one of our greatest public health challenges. Targeted use of antibiotics (ABs) can reduce the occurrence and spread of AMR and boost the effectiveness of treatment. …”
Get full text

Cerebral Blood Flow in Orthostatic Intolerance by Muhammad Shahzeb Khan, Amanda J. Miller, Arooba Ejaz, Jeroen Molinger, Parag Goyal, David B. MacLeod, Ashley Swavely, Elyse Wilson, Meghan Pergola, Harikrishna Tandri, Camille Frazier Mills, Satish R Raj, Marat Fudim

Get full text

Revisiting Key Entry Routes of Human Epidemic Arboviruses into the Mainland Americas through Large-Scale Phylogenomics by Túlio De Lima Campos, Ricardo Durães-Carvalho, Antonio Mauro Rezende, Otávio Valério de Carvalho, Alain Kohl, Gabriel Luz Wallau, Lindomar José Pena

“…Understanding how the virus circulates and moves from one country to another is of paramount importance to assist government and health officials in anticipating future epidemics, as well as to take steps to help control or mitigate the spread of the virus. …”
Get full text

What impact has the NIHR Academic Clinical Fellowship (ACF) scheme had on clinical academic careers in England over the last 10 years? A retrospective study by James Neilson, David Jones, Sally Clough, James Fenton, Helen Harris-Joseph, Leesa Rayton, Caroline Magee, Lisa Ann Cotterill

“…This study examines the impact of the ACF model, over its first 10 years, in developing clinical academic careers by tracking the progression of ACF trainees.Design Retrospective analysis of National Institute for Health Research (NIHR) ACF career progression. This was performed using mixed methods including routine data collections of career destination, analysis of application rates to doctoral level fellowships and supplemented by survey information that captured the perceived benefits and challenges from previous ACFs and their current career activities.Participants 1239 NIHR ACFs who completed or left their posts between 2006 and March 2015.Results ACFs are perceived by the candidate population as attractive posts, with high numbers of applications leading to high fill rates. …”
Get full text

Obesity-Linked Gut Microbiome Dysbiosis Associated with Derangements in Gut Permeability and Intestinal Cellular Homeostasis Independent of Diet by Ravinder Nagpal, Tiffany M. Newman, Shaohua Wang, Shalini Jain, James F. Lovato, Hariom Yadav

Get full text

Modulation of Second Messenger Signaling in the Brain Through PDE4 and PDE5 Inhibition: Therapeutic Implications for Neurological Disorders by Min Kyu Park, Hyun Wook Yang, Seo Young Woo, Dong Yeon Kim, Dae-Soon Son, Bo Young Choi, Sang Won Suh

“…This review synthesizes current evidence on the roles of PDE4 and PDE5 in neurological health and disease, focusing on their regulation of second messenger pathways and their implications for brain function. …”
Get full text

Deformities due to Leprosy in Children under Fifteen Years Old as an Indicator of Quality of the Leprosy Control Programme in Brazilian Municipalities by Francisco Carlos Félix Lana, Angélica da Conceição Oliveira Coelho Fabri, Fabiana Nascimento Lopes, Ana Paula Mendes Carvalho, Fernanda Moura Lanza

“…This situation contributes to maintaining the chain of disease transmission in the area and indicates that health care services should intensify leprosy control.…”
Get full text

Virtual reality technology improves the gait and balance function of the elderly: a meta-analysis of randomized controlled trials by Junyu Chen, Shuxia Yan, Haiyan Yin, Dan Lin, Ziqi Mei, Zichun Ding, Meng Wang, Yamei Bai, Guihua Xu

“…Introduction Improving the gait and balance function is an important part of the health of the elderly. This study aimed to conduct a meta-analysis to evaluate the effects of virtual reality (VR) technology on the gait and balance function of the elderly. …”
Get full text

Reduced Plasma Nonesterified Fatty Acid Levels and the Advent of an Acute Lung Injury in Mice after Intravenous or Enteral Oleic Acid Administration by Cassiano Felippe Gonçalves de Albuquerque, Patrícia Burth, Mauricio Younes Ibrahim, Diogo Gomes Garcia, Patrícia Torres Bozza, Hugo Caire Castro Faria Neto, Mauro Velho Castro Faria

“…The significant reduction in blood NEFA levels detected after OLA enteral administration can contribute to the already known health benefits brought about by unsaturated-fatty-acid-enriched diets.…”
Get full text

Enhanced multivariate data fusion and optimized algorithm for comprehensive quality profiling and origin traceability of Chinese jujube by Peng Chen, Xiaoli Wang, Rao Fu, Xiaoyan Xiao, Yu Li, Tulin Lu, Tao Wang, Qiaosheng Guo, Peina Zhou, Chenghao Fei

Get full text