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Catechin-Albumin Conjugates: Enhanced Antioxidant Capacity and Anticancer Effects
Published 2022-01-01“…The results indicated that the FITC-labelled CT–HSA was incorporated into HeLa cells in a concentration-dependent manner. The CT–HSA enhanced the binding of anticancer drugs (5-fluorouracil (5-Fu) and mitomycin C (MMC)) comparing with HSA, and the CT–HSA mixed with 5-Fu or MMC decreased significantly the HeLa cell viability as compared with the same concentration of each drug. …”
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22
Comparative Cytotoxic Activity of Wild Harvested Stems and In Vitro-Raised Protocorms of Dendrobium chryseum Rolfe in Human Cervical Carcinoma and Glioblastoma Cell Lines
Published 2021-01-01“…The comparative cytotoxic activities of the wild and in vitro-raised protocorms were evaluated in human cervical carcinoma (HeLa) and human glioblastoma (U251) cell lines by MTT assay. …”
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23
Exploring the Relationship between the Inhibition Selectivity and the Apoptosis of Roscovitine-Treated Cancer Cells
Published 2013-01-01“…The antitumor activity of roscovitine was tested in four cervical carcinoma cells: C33A, HCE-1, HeLa, and SiHa. The effects of roscovitine on ATP Lite assay, cell cycle, and apoptosis were assessed. …”
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24
Colony-Forming and Cell Viability Assay to Assess Nanotoxicity of Maleic Acid and N-vinyl Caprolactam-Based Nanoarchitectures
Published 2025-01-01“…The cytotoxicity of Org-MMT, poly(MA-alt-VCL), and their nanocomposites were tested on HeLa (cervical carcinoma), A549 (lung cancer), and HDF (human dermal fibroblast) cells using MTT and colony formation assays. …”
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25
Advances in Surface Plasmon Resonance-Based Biosensor Technologies for Cancer Cell Detection
Published 2022-01-01“…Using the finite element method-based simulation technique, the sensitivity obtained as 195.4 degree/RIU, 167.6 degree/RIU, 212.4 degree/RIU, 168.4 degree/RIU, 212.4 degree/RIU, 186.6 degree/RIU, 218.6 degree/RIU, 195.4 degree/RIU, 203.6 degree/RIU, 202.6 degree/RIU 203.6 degree/RIU, and 202.6 for basal (skin cancer), basal (normal cell), HeLa (cervical cancer), MCF-7 (breast cancer), HeLa (normal cell), Jurkat (blood cancer), Jurkat (normal cell), PCI-2 (adrenal gland cancer), PCI-2 (normal cell), MDA-MB-231 (breast cancer), MDA-MB-231 (normal cell), MCF-7 (breast cancer), and MCF-7 (normal cell), respectively, and other performance parameters such as detection accuracy, figure of merit, and full width and half maximum (FWHM) are also evaluated.…”
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26
Ecofriendly Synthesis of Silver Nanoparticles from Garden Rhubarb (Rheum rhabarbarum)
Published 2016-01-01“…In addition, cytotoxicity of RR-SNPs against in vitro human epithelial carcinoma (HeLa) cell line showed a dose-response activity. …”
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27
Radiosensitivity and Induction of Apoptosis by High LET Carbon Ion Beam and Low LET Gamma Radiation: A Comparative Study
Published 2014-01-01“…DNA damage, cell killing, and induction of apoptosis were significantly higher for 12C than gamma radiation in HeLa. Cell killing and apoptosis were further elevated upon knocking down of PARP-1. …”
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DNA Cleavage, Cytotoxic Activities, and Antimicrobial Studies of Ternary Copper(II) Complexes of Isoxazole Schiff Base and Heterocyclic Compounds
Published 2014-01-01“…In vitro antitumor activity of Cu(II) complexes was assayed against human cervical carcinoma (HeLa) cancer cells and it was observed that few complexes exhibit good antitumor activity on HeLa cell lines. …”
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GC-MS Analysis of Bioactive Compounds in Methanolic Extracts of Papaver decaisnei and Determination of Its Antioxidants and Anticancer Activities
Published 2022-01-01“…The anticancer of P. decaisnei was found as 125.3–388.4 μg/mL against all tested cell lines (Caco-2, MCF-7, and HeLa). The detected alkaloids and bioactivity of P. decaisnei encourage future isolation of those remarkable alkaloids (reomerine) for potential usage in the pharmaceutical industry.…”
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Cytotoxicity Potential of Endophytic Fungi Extracts from Terminalia catappa against Human Cervical Cancer Cells
Published 2020-01-01“…Moreover, a higher reduction in the percentage of viable cells was observed in the HeLa control cells (93.6 ± 0.3), but the percentages of viable HeLa cells were 37 ± 0.05 and 45 ± 0.1, respectively, for the 50 µg/ml and 80 µg/ml treatments with the N97 extract. …”
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31
Antiproliferative and genotoxic potential of xanthen-3-one derivatives
Published 2019-12-01“…Compounds were screened against HeLa, SW620, HepG2 and A549 tumor cell lines. Compound with the trifluormethyl group on C-4’ position of the phenyl ring showed the best inhibitory activity towards HeLa and A549 tumor cells with IC50 of 0.7 and 4.1 µmol L−1, resp. …”
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32
The Effects of Microseconds Electroporation on Pore Size, Viability and Mitochondrial Membrane Potential of Cervical Cancer Cells
Published 2025-01-01“…Results: The surface of the electroporated cell membrane exhibited a relatively uniform pore population. The viability of HeLa cells was significantly reduced with increasing electric field intensities. …”
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33
Oleuropein in olive leaf, branch, and stem extracts: stability and biological activity in human cervical carcinoma and melanoma cells
Published 2023-12-01“…The data show that all extracts had a similar dose-dependent effect on cell viability in HeLa cells, while the effect of LE on melanoma A375 and A375M, and HaCaT cells was cell-line dependent.…”
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34
Antimicrobial and Antibiofilm Activities of 4,5-Dihydro-1H-pyrazole-1-carboximidamide Hydrochloride against Salmonella spp.
Published 2021-01-01“…Further, the cytotoxicity of the compounds was evaluated by cell viability assays using cultures of HeLa and Vero cell lines, and the mutagenic potential was assessed by the Ames test. …”
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35
Cancer Stem Cells from Tumor Cell Lines Activate the DNA Damage Response Pathway after Ionizing Radiation More Efficiently Than Noncancer Stem Cells
Published 2019-01-01“…We aimed to determine the molecular basis of radioresistance and first compared the response to ionizing radiation (IR) between cancer stem cell-enriched cultures grown as spheres and conventional tumor cell line cultures grown as monolayer, from HeLa and MCF-7 cancer cell lines. To verify that our sphere cultures were enriched in CSC, we evaluated the double staining of CD49f and ALDH activity for HeLa cells by flow cytometry. …”
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Design and development of novel 1,2,3-triazole chalcone derivatives as potential anti-osteosarcoma agents via inhibition of PI3K/Akt/mTOR signalling pathway
Published 2022-09-01“…The most significant inhibitory activity was observed for compound 4e against all cell lines (MG-63, HepG2, A549 and HeLa), still somewhat lower to comparable to that of gedatolisib, but with the highest potency against MG-63 cells. …”
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Hybrid peptides inspired by the RWQWRWQWR sequence inhibit cervical cancer cells growth in vitro
Published 2024-09-01“…In vitro cytotoxicity of hybrid peptides in human cervical cancer cells lines HeLa and Ca Ski was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. …”
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38
TRAF2 and RIPK1 redundantly mediate classical NFκB signaling by TNFR1 and CD95-type death receptors
Published 2025-01-01“…Evaluation of a panel of five tumor cell lines (HCT116-PIK3CAmut, SK-MEL-23, HeLa-RIPK3, HT29, D10) with TRAF2 knockout revealed in two cell lines (HT29, HeLa-RIPK3) a sensitizing effect for death receptor-induced necroptosis and in one cell line (D10) a mild sensitization for TNFR1-induced apoptosis. …”
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Synthesis of Polymer Assembled Mesoporous CaCO3 Nanoparticles for Molecular Targeting and pH-Responsive Controlled Drug Release
Published 2020-01-01“…The cytotoxicity, targeting effect, and drug release of human cervical cancer cell line (HeLa) were studied by cell vitality and imaging experiments. …”
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Green Synthesis and Characterization of Biocompatible Gold Nanoparticles Using Solanum indicum Fruits
Published 2013-04-01“…The cytotoxicity of the synthesized AuNPs were tested on two different human cancer cell lines, HeLa and MCF‐7 and were found to be nontoxic, thus providing an opportunity to be used in biomedical applications.…”
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