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    Impact of Antimicrobial Stewardship and Infection Prevention and Control Programmes on Antibiotic Usage and A. baumannii resistance: A 2016–2023 Multicentre Prospective Study by Liu L, Liu B, Li L, Li Y, Zhou X, Li Q

    Published 2025-02-01
    “…Lei Liu,1,2,* Bin Liu,1,2,* Liang Li,1,2 Yu Li,3 Xiangdong Zhou,1,2 Qi Li1,2 1Department of Respiratory Medicine, The First Affiliated Hospital, Hainan Medical University, Haikou, Hainan, People’s Republic of China; 2Hainan Province Clinical Medical Center of Respiratory Disease, Haikou, Hainan, People’s Republic of China; 3Department of Respiratory Medicine, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qi Li, Email lqlq198210@sina.comObjective: This study assesses the efficacy of antimicrobial stewardship (AMS) and infection prevention and control programmes (IPCP) in guiding the use of antibiotics and the control of A. baumannii (AB) resistance at multiple medical centres.Methods: We evaluated the effectiveness of the policy on antibiotic consumption and AB resistance by determining the relationship between the defined daily doses (DDD) for antibiotics – or alcohol-based hand gel (ABHG) consumption – and the incidence of carbapenem-resistant AB (CR-AB), multidrug-resistant AB (MDR-AB) and extensively drug-resistant AB (XDR-AB) at two medical centers from 2016– 2023.Results: In total, 4057 AB isolates were collected; 64.95% of the AB isolates were CR, 59.48% were MDR and 1.41% were XDR. …”
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  12. 1172

    N-2-Hydroxypropyl Trimethyl Ammonium Chloride Chitosan-Aluminum Nano-Adjuvant Elicit Strong Immune Responses in Porcine Epidemic Diarrhea Inactivated Vaccine by Jin Z, Liu J, Guo S, Xu S, Gong X, Zhang C, Zhao K

    Published 2025-01-01
    “…Zheng Jin,1 Jiali Liu,1 Sihan Guo,2 Shangen Xu,1 Xiaochen Gong,1,3 Chunjing Zhang,3 Kai Zhao1,2 1Zhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation, Taizhou Key Laboratory of Biomedicine and Advanced Dosage Forms, School of Life Sciences, Taizhou University, Taizhou, Zhejiang, 318000, People’s Republic of China; 2Engineering Research Center of Agricultural Microbiology Technology, Ministry of Education, Heilongjiang University, Harbin 150080, China; Key Laboratory of Microbiology, College of Heilongjiang Province, School of Life Sciences, Heilongjiang University, Harbin, Heilongjiang, 150080, People’s Republic of China; 3School of Medical Technology, Qiqihar Medical University, Qiqihar, Heilongjiang, 161006, People’s Republic of ChinaCorrespondence: Kai Zhao; Chunjing Zhang, Email zybin395@126.com; cjzhang2005@163.comBackground: Porcine epidemic diarrhea virus (PEDV) inactivated vaccine lacks an effective vaccine adjuvant as an immune activator. …”
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