Epidemiological trends of head and neck Cancer survivors in Alberta: towards improved understanding of the burden of disease by Jin Soo Song, Patrick Vallance, Vincent Biron, Caroline C. Jeffery

“…Abstract Background With an increase in the incidence of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) and more favourable survival outcomes, there is now a population of head and neck cancer survivors that are different from preceding decades. …”
Get full text

REFERENCE POINTS OF THE PATHOGENESIS OF THE PHENOMENON OF MODEL FORMATION RISKY REPRODUCTIVE BEHAVIOR TEENAGE GIRLS by Ирина Вячеславовна Бабенко-Сорокопуд

“…As the severity of menstrual disorders increased, the share of teenage girls who had risky sexual practices increased, which leads to an increase in the number of sexually transmitted diseases, including HPV/HIV, unplanned pregnancy, its termination. …”
Get full text

MEKANISME KO-KEMOTERAPI EKSTRAK ROSELLA (Hibiscus sabdariffa. L) DENGAN DOXORUBICIN PADA SEL KANKER SERVIKS (HeLa) SECARA IN VITRO by Intan Daud, Laela Hayu Nurani, Moch. Saiful Bachri, Citra Ariani Edityaningrum, Muhammad Ma’ruf

“… Kanker serviks disebabkan karena paparan Human Papilloma Virus (HPV) melalui hubungan seksual yang dapat diobati dengan Doxorubicin. …”
Get full text

Squamous cell carcinoma in a kidney transplant recipient after 26 years by Carolina da Silva Nunes, Andreia Bufalino, Cláudia Maria Navarro, Jorge Esquiche León, Héric de Souza Camargo, Elaine Maria Sgavioli Massucato

“…The oral cavity is a predilection site in the head and neck region, and many lesions are associated with human papillomavirus (HPV), an oncogenic virus whose infection can be potentiated by chronic immunosuppression in transplant patients. …”
Get full text

Combined spatial Keratin expression profiles at the invasive front represent a prognostic classifier for head and neck cancer by Peter D. Haughton, Wisse E. Haakma, Sven van Kempen, Emma J. de Ruiter, Stefan M. Willems, Patrick W.B. Derksen

“…Here, we have assessed a panel of Keratin markers in four HPV negative HNSCC patient-derived organoid (PDO) models and their corresponding primary patient tissue to define spatial expression profiles of basal and supra-basal Keratins during invasion in Collagen-I matrices. …”
Get full text

Prognostic Significance and Therapeutic Potential of SERPINE1 in Head and Neck Squamous Cell Carcinoma by Changyu Zhu, Heshu Liu, Zhixin Li, Yijun Shi, Jingyang Zhao, Yuping Bai, Qian Chen, Wei Li

“…It was observed that, particularly in human papillomavirus (HPV) negative HNSCC, SERPINE1 exhibited elevated expression levels, correlating with poorer prognosis. …”
Get full text

Role of Regulatory B Cells in the Progression of Cervical Cancer by Zhifang Chen, Yuejie Zhu, Rong Du, Nannan Pang, Fengbo Zhang, Di Dong, Jianbing Ding, Yan Ding

“…In addition, the Breg cell percentage was closely related to the FIGO stages, lymph node metastasis, tumor differentiation, HPV infection, and the tumor metastasis of cervical cancer (P<0.05). …”
Get full text

Cervical cancer screening utilization among HIV-positive women in Edo State, Nigeria by Ngozi R. Osunde, Mercy N. Anayo, Ona Patience, Favour E. Omoregie

“…Background: The enhanced risk of cervical cancer among women with human immunodeficiency virus (HIV) stems from the close association between HIV and increased rates of persistent human papillomavirus (HPV) infection. Detecting pre-malignant lesions early through screening is crucial, as cervical cancer is preventable. …”
Get full text

Exploring preconception health in adolescents and young adults: Identifying risk factors and interventions to prevent adverse maternal, perinatal, and child health outcomes-A scopi... by Zahra Ali Padhani, Komal Abdul Rahim, Gizachew A Tessema, Jodie C Avery, Negin Mirzaei Damabi, Patience Castleton, Rehana A Salam, Salima Meherali, Zohra S Lassi

“…Micronutrient supplementation contributed to reducing anaemia among adolescent mothers; however, human papillomavirus (HPV) and herpes simplex virus (HSV) vaccination had little to no impact on stillbirths, ectopic pregnancies, and congenital anomalies. …”
Get full text

A Metabolic Gene Signature to Predict Overall Survival in Head and Neck Squamous Cell Carcinoma by Zeng-Hong Wu, Yun Tang, Yue Zhou

“…On the other hand, the AUC for age, gender, stage, T, M, N, smoking, and HPV16-pos was 0.599, 0.531, 0.622, 0.606, 0.616, 0.550, 0.614, 0.519, and 0.397, respectively, in the GEO dataset. …”
Get full text

A Clinical Prediction Model for Pathologic Upgrade to Invasive Carcinoma Following Conization of Cervical High‐Grade Squamous Intraepithelial Lesions by Qiao Liu, Jing Yang, Hui Cheng, Chuqiang Shu, Yi Tang, Jing Zhao

“…The predictive model included age, contact bleeding symptoms, HPV16/18 infection, HSIL cytology, cervical biopsy pathology diagnosis level, suspicious stromal infiltration in the biopsy pathology diagnosis, and endocervical curettage HSIL. …”
Get full text

National and subnational plans for primary prevention and early detection of oral and oropharyngeal cancer: a scoping review by Marcia Frias Pinto Marinho, Maria Clara Frias Lobo Marinho, Guido Artemio Marañón-Vásquez, Keith Bullia da Fonseca Simas, Mário José Romañach, Aline Corrêa Abrahão, Maria Augusta Visconti Rocha Pinto, Lucianne Cople Maia de Faria, Michelle Agostini

“…Tobacco use was the most discussed oral and oropharyngeal cancer risk factor in primary prevention plans (63.7%), followed by HPV infection (54%) and alcohol consumption (35.5%). …”
Get full text

Genomic landscape of head and neck cancer in Asia: A comprehensive meta-analysis of 1016 samples by Srikanth S. Manda, Nafisa Arfa, Neha Sharma, Aparna R. Parikh, Thomas J. Roberts, Sewanti Limaye, Venkataraman Ramachandran, Kumar Prabhash, Moni A. Kuriakose, Prashant Kumar

“…Head and neck cancer (HNC) is a diverse group of malignancies arising in the mucosal linings of the oral cavity, pharynx, and larynx, influenced by factors such as tobacco use, alcohol consumption, and human papillomavirus (HPV) infection. This study conducts a comprehensive meta-analysis of the mutational landscape of HNC across Asian cohorts, encompassing India, Korea, Japan, China, Singapore, and Saudi Arabia. …”
Get full text

Malignant transformation of proliferative Verrucous Leukoplakia—systematic review & meta-analysis by Khadijah Mohideen, Snehashish Ghosh, Chandrasekaran Krithika, Mutaz Ali-Hassan, Revant Chole, Safal Dhungel

“…Tobacco and alcohol showed weak associations, with most patients being non-smokers (59.54%) and non-drinkers (78.18%). HPV and candida infection positivity were tested in only a few studies and noted in a limited number of cases (33.3% and 38.46%, respectively). …”
Get full text

Caerin 1.1/1.9-mediated antitumor immunity depends on IFNAR-Stat1 signalling of tumour infiltrating macrophage by autocrine IFNα and is enhanced by CD47 blockade by Junjie Li, Yuandong Luo, Quanlan Fu, Shuxian Tang, Pingping Zhang, Ian H. Frazer, Xiaosong Liu, Tianfang Wang, Guoying Ni

“…Abstract Previously, we demonstrated that natural host-defence peptide caerin 1.1/caerin 1.9 (F1/F3) increases the efficacy of anti-PD-1 and therapeutic vaccine, in a HPV16 + TC-1 tumour model, but the anti-tumor mechanism of F1/F3 is still unclear. …”
Get full text

High-Grade Cervical Intraepithelial Neoplasia: Impact of Colposcopic Lesion Area on Systemic Immune Responses by Mantoani PTS, Micheli DC, Jammal MP, Vieira JH, Michelin MA, Ferreira CGX, Silva HN, Murta EFC, Nomelini RS

“…The objectives of the study were to determine whether colposcopic lesion area is associated with serum levels of cytokines IL (interleukin) − 1, IL-6, IL-8, IL-10, IL-12 and TNF-α in precursor lesions of cervical cancer.Methods: The study population comprised patients with high-grade squamous intraepithelial lesion who had undergone colposcopy, cervical biopsy, and measurements of serum cytokines by ELISA (Enzyme-Linked Immunosorbent Assay). Genotyping for HPV (human papillomavirus) 16, 18, 45 and 52 was performed by PCR (Polymerase Chain Reaction). …”
Get full text

Application of photodynamic therapy with 5-aminolevulinic acid and fractional CO2 laser for the management of recalcitrant plantar warts by Jiaoquan Chen, Xinyi Xie, Yingxue Liu, Fengyi Chen, Yeqing Gong, Bihua Liang, Yiling Wu, Shiqi He, Yueming Li, Huilan Zhu, Shaoyin Ma

“…Significance: Plantar warts, benign lesions on the soles of the feet, are caused by the human papillomavirus (HPV) infecting keratinocytes. Complete eradication of these warts is challenging, often leading to recurrences. …”
Get full text

Human Leucocyte Antigen Class II Risk and Protective Alleles in Women with Cervical Intraepithelial Neoplasia by Olga Plisko, Jana Žodžika, Irina Jermakova, Inta Liepniece-Karele, Jeļena Eglīte, Dace Rezeberga

“… Background: Persistent human papillomavirus (HPV) infection is a necessary cause for development of cervical precancerous lesions and cervical cancer, however, only a small percentage of women progress to cervical cancer. …”
Get full text

Systematic collection, annotation, and pattern analysis of viral vaccines in the VIOLIN vaccine knowledgebase by Anthony Huffman, Mehul Gautam, Arya Gandhi, Priscilla Du, Lauren Austin, Kallan Roan, Jie Zheng, Yongqun He, Yongqun He

“…., viral entry, assembly, exit, and immune evasion) as identified in top ranked human, animal vaccines, and HPV vaccines. The vaccine antigen proteins also show up in different virion locations in viruses such as HRSV vaccines. …”
Get full text

Immunogenetics of longevity and its association with human endogenous retrovirus K by Lisa M. James, Lisa M. James, Lisa M. James, Apostolos P. Georgopoulos, Apostolos P. Georgopoulos, Apostolos P. Georgopoulos, Apostolos P. Georgopoulos

“…Since each individual carries 12 classical HLA alleles (6 alleles of each Class I and Class II), we determined in silico the median predicted binding affinity for each individual (across the 12 HLA alleles) and each of 13 common viruses (Human Herpes Virus 1 [HHV1], HHV2, HHV3, HHV4, HHV5, HHV6A, HHV6B, HHV7, HHV8, human papilloma virus [HPV], human polyoma virus [JCV], human endogenous retrovirus K [HERVK], and HERVW). …”
Get full text