Investigation on extended care needs of patients with hypertensive intracerebral hemorrhage (高血压性脑出血患者延续性护理服务需求调查) by QIU Yajiao (邱亚娇), LIANG Hui (梁慧), WANG Fang (王芳)

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FTO attenuates TNF-α-induced damage of proximal tubular epithelial cells in acute pancreatitis-induced acute kidney injury via targeting AQP3 in an N6-methyladenosine-dependent man... by Xinghui Li, Qi Liang, Lu Liu, Shujun Chen, Yong Li, Yu Pu

“…Therefore, the aim of this study is to explore the association of FTO and AQP3 on proximal tubular epithelial cell damage in SAP-induced AKI.Methods An in-vitro AKI model was established in human proximal tubular epithelial cells (PTECs) HK-2 via tumor necrosis factor-α (TNF-α) induction (20 ng/mL), after which FTO and AQP3 expression was manipulated and quantified by quantitative real-time PCR and Western blotting. …”
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Status quo and research progress of Traditional Chinese Medicine professional training based on the Traditional Chinese Medicine nursing training base (以中医护士培训基地为依托的中医护理专业化培训现状及研究进... by WANG Yuan (王媛), WANG Bei (王蓓), WANG Fengmei (王凤美), ZHANG Xixia (章细霞)

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Distinct dynamic regulation of pectoralis muscle metabolomics by insulin and the promotion of glucose-lipid metabolism with extended duration by Xiangli Zhang, Pengfei Du, Ziyang Wang, Yao Zhu, Xuemeng Si, Wen Chen, Yanqun Huang

“…Early insulin inhibited glycolysis, evidenced by the reduction in phosphoenolpyruvate levels and hexokinase 2 (HK2) expression; however, insulin promoted glucose uptake through the activation of glucose transporter 4 (GLUT4) and enhanced glycolysis, accompanied by elevated fatty acid metabolism at the later phase.In conclusion, insulin dynamically regulates the metabolomics of the pectoralis muscle over time. …”
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Exploring avocado consumption and health: a scoping review and evidence map by Stephen A. Fleming, Tristen L. Paul, Rachel A. F. Fleming, Alison K. Ventura, Megan A. McCrory, Corrie M. Whisner, Paul A. Spagnuolo, Louise Dye, Jana Kraft, Jana Kraft, Nikki A. Ford

“…ObjectiveThis scoping review evaluates the breadth of research on avocado intake and health, considering all populations and health outcomes (registered on Open Science Foundation at https://osf.io/nq5hk).DesignAny human intervention or observational study where effects could be isolated to consumption of avocado were included. …”
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Research progress on application of digital health interventions in patients with cutaneous ureterostomy (数字健康干预在输尿管皮肤造口患者中的应用进展) by JI Xuebi (吉学碧), WANG Jun (王俊), WANG Ping (王萍), YE Yingao (叶迎奥), WANG Haifeng (王海峰)

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Research progress on the application of bedside lung ultrasound in ICU nursing (床旁肺部超声在ICU护理中应用的研究进展) by TAN Huiting (谭慧婷), WANG Fengying (王凤英), LI Fangfang (李芳芳), GUO Yanyun (郭艳云), XUE Chao (薛超)

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Bian-stone ironing and rubbing therapy combined with Traditional Chinese Medicine penetration therapy for postoperative constipation in a lung cancer patient undergoing chemotherap... by GAO Yaqian (高雅倩), GUO Huanli (郭换利), HUANG Yanping (黄砚萍), FENG Wenying (冯文英), ZHANG Guohong (张国红), ZHANG Xuelian (张雪莲)

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Current research status of Traditional Chinese Medicine nursing for patients with sleep disorder after stroke (脑卒中后睡眠障碍中医护理技术研究现状) by HU Haixia (胡海霞), LIANG Haiyun (梁海云), HAN Xuelian (韩雪莲), XIE Ying (谢影), LI Yanmei (李艳梅)

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Research progress of network-based interventions on self-care ability of patients with chronic heart failure (慢性心力衰竭患者自我护理能力网络干预的研究进展) by ZHAI Kaijing (翟凯静), ZHANG Yuqing (张雨晴), LIU Wei (刘薇), QIAO Zhihui (乔志桧), FANG Cui (方璀), FU Conghan (付聪晗)

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Nursing of a patient with radiotherapy- and chemotherapy-induced adverse reactions treated with aruricualr acupoint pressing combined with meridian acupoint Tuina (耳穴贴压联合经穴推拿治疗放化疗后... by JIN Yi (金艺), MIN Tingyan (闵婷燕)

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Astragalin: A Bioactive Phytochemical with Potential Therapeutic Activities by Ammara Riaz, Azhar Rasul, Ghulam Hussain, Muhammad Kashif Zahoor, Farhat Jabeen, Zinayyera Subhani, Tahira Younis, Muhammad Ali, Iqra Sarfraz, Zeliha Selamoglu

“…It carries out the aforementioned activities by the regulation and modulation of various molecular targets such as transcription factors (NF-κB, TNF-α, and TGF-β1), enzymes (iNOS, COX-2, PGE2, MMP-1, MMP-3, MIP-1α, COX-2, PGE-2, HK2, AChe, SOD, DRP-1, DDH, PLCγ1, and GPX), kinases (JNK, MAPK, Akt, ERK, SAPK, IκBα, PI3K, and PKCβ2), cell adhesion proteins (E-cadherin, vimentin PAR-2, and NCam), apoptotic and antiapoptotic proteins (Beclin-1, Bcl-2, Bax, Bcl-xL, cytochrome c, LC3A/B, caspase-3, caspase-9, procaspase-3, procaspase-8, and IgE), and inflammatory cytokines (SOCS-3, SOCS-5, IL-1β, IL-4, IL-6, IL-8, IL-13, MCP-1, CXCL-1, CXCL-2, and IFN-γ). …”
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Nursing of a patient undergoing trans-apical transcatheter aortic valve replacement for severe aortic insufficiency (心尖途径经导管主动脉瓣置换术治疗重度主动脉瓣关闭不全1例护理体会)... by XU Yuanhua (徐远华), HE Hui (何慧), ZHAO Jianhua (赵建华), DENG Zibin (邓梓彬), ZOU Minghui (邹明辉), YANG Yang (杨扬), PAN Gang (潘港)

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Integrated traditional Chinese and western medicine nursing of a patient with Guillain-Barre syndrome complicated with dissociative disorder (1例吉兰-巴雷综合征合并分离性障碍患者的中西医结合护理体会)... by ZHOU Yuan (周媛), LI Qian (李倩), LIU Jianmei (刘健玫), CAI Chang (蔡畅), MA Haili (马海利), FENG Qingqing (冯青青)

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Application of 5G mobile nurse workstation combined with intelligent nursing interaction system in management of nursing shift (5G移动护士站系统结合护理白板在护理交接班中的应用)... by HUANG Liming (黄丽明), LI Chunrong (李春容)

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Does an increase in physiological indexes predict better cognitive performance: the PhyCog randomised cross-over protocol in type 2 diabetes by Frederic Dutheil, Guillaume T Vallet, Igor Tauveron, Julien S Baker, Valentin Magnon, Jordan Mille, Valentin Brusseau, Laetitia Silvert, Marie Izaute

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Effect of auricular acupoint pressing combined with acupoint application in the treatment of senile constipation (耳穴压豆联合穴位贴敷治疗老年性便秘效果观察) by KAN Haiying (坎海英), ZHOU Weihua (周维华)

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ROS-ERK Pathway as Dual Mediators of Cellular Injury and Autophagy-Associated Adaptive Response in Urinary Protein-Irritated Renal Tubular Epithelial Cells by Jian-kun Deng, Xueqin Zhang, Hong-luan Wu, Yu Gan, Ling Ye, Huijuan Zheng, Zebing Zhu, Wei Jing Liu, Hua-feng Liu

“…What is more, ERK inhibitor U0126 could decrease the release of neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (KIM-1), and the number of apoptotic cells induced by urinary proteins, indicating the damaging effects of ERK pathway in mediating cellular injury and apoptosis in HK-2 cells. Interestingly, we also found that the increased expression of microtubule-associated protein 1 light chain 3 (LC3)-II (a key marker of autophagy) and the decreased expression of p62 (autophagic substrate) induced by urinary proteins were reversed by U0126, suggesting autophagy was activated by ERK pathway. …”
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Evaluation of modified interventions of integrated Traditional Chinese and western medicine in nursing of stroke patients (中风患者中西医结合优化护理干预效果观察)... by LI Yanmin (李艳敏), HUANG Chaoping (黄朝萍)

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Traditional Chinese Medicine nursing of a patient with type 2 diabetes complicated with hypertension (1例2型糖尿病合并高血压患者的中医特色护理体会) by ZHANG Ji (张继), LIU Ai (刘爱), ZHANG Min (张敏), ZHAO Lina (赵丽娜), MING Yue (明月), ZUO Lin (左琳), FENG Ying (冯莹), ZHAO Zitong (赵紫彤)

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