TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease by Yunxia Du, Ming Wu, Shan Song, Yawei Bian, Yonghong Shi

“…Simultaneously, TXNIP interference inhibited epithelial-to-mesenchymal transformation (EMT), collagen I and fibronectin expression, and mTORC1 activation, increased TFEB nuclear translocation, and promoted autophagy restoration in HK-2 cells exposed to high glucose (HG). Rapamycin, an inhibitor of mTORC1, increased TFEB nuclear translocation and autophagy in HK-2 cells under HG conditions. …”
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lncRNA SNHG14 Plays a Role in Sepsis-Induced Acute Kidney Injury by Regulating miR-93 by Chuanchuan Shi, Yuqian Zhao, Qi Li, Jianguo Li

“…Increased expression of SNHG14 was observed in LPS-induced HK-2 cells, and this was due to the activation of the TLR4/NF-κB pathway. …”
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miR-16-5p aggravates sepsis-associated acute kidney injury by inducing apoptosis by Han Li, Junyan Duan, Tongtong Zhang, Yingjie Fu, Yue Xu, Hongjun Miao, Xuhua Ge

“…In vitro, the expression level of miR-16-5p in HK-2 cells treated with 10 μg/mL lipopolysaccharide (LPS) increased by more than 2 times. …”
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Measuring the Service Quality of Public Libraries in Ankara by Özlem Şenyurt Topçu, Bülent Yılmaz

“…The libraries included in this research are Cebeci Public Library (Cebeci HK), Mamak County Public Library (Mamak İHK) and Or-An Sevgi Yılı Public Library (Or-An HK) which are chosen from the upper, middle and lower socio-economic regions in Ankara. …”
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Olive tourism in Andalusia by Hervé Théry

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Group 2 Innate Lymphoid Cells Participate in Renal Fibrosis in Diabetic Kidney Disease Partly via TGF-β1 Signal Pathway by Cuiping Liu, Ludan Qin, Jingya Ding, Luping Zhou, Chenlin Gao, Ting Zhang, Man Guo, Wei Huang, Zongzhe Jiang, Yang Long, Yong Xu

“…The expression of TGF-β1, FN, and collagen1 was significantly upregulated in HK-2 cells induced by IL-4 or IL-13 (P<0.05). Moreover, the IL-4Rα and IL-13Rα1 mRNA in HK2 cells were increased followed by high glucose alone or combined with IL-4 or IL-13, but the differences were not statistically significant (P>0.05). …”
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NIR‐II emissive biohybrid nanovesicles as mild‐temperature photothermal antibiofilm agents against acute bacterial skin and skin‐structure infections by Ji Wang, Zhihao Wu, Xiaoxi Ma, Zhihui Huang, Haorong Dong, Jinxin Zhang, Xiaoming Liu, Pengfei Zhang, Shuhuai Yao

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Evaluation of the willingness to perform cardiopulmonary resuscitation (CPR) with automated external defibrillator (AED) among Hong Kong Chinese using the theory of planned behavio... by Victor C W Tam, Anthony Wai Leung Kwok

“…Introduction Bystander cardiopulmonary resuscitation (CPR) and defibrillation by an automated external defibrillator (AED) in out-of-hospital cardiac arrest (OHCA) events were low in Hong Kong (HK). This study evaluated the willingness and associated factors of performing CPR with AED in HK using the theory of planned behaviour (TPB).Methods A total of 1449 responses from HK Chinese aged 15–64 years were collected in a cross-sectional online survey using convenience sampling on social media including Facebook, Instagram and WhatsApp. …”
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Characterizations and growth kinetics of the borided layer formed on pure nickel by molten salt electrolysis by Wang B.-X., Yuan W.-L., Wang Z.-Y., Li J.-X., Ma H.-Z., Song Y.-H.

“…After 1 h of boronizing, the hardness of the silicon rich borides is 966 HK, which is a little lower than that of the nickel borides (992-1008 HK); the surface hardness reached 1755 HK after 4 h electrolysis. …”
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应用非同位素aPCR-SSCP法检测P53基因突变

“…建立一种非同位素的不对称聚合酶链反应－单链构象多态性技术（ａＰＣＲ－ＳＳＣＰ）：通过不对称ＰＣＲ（ａＰＣＲ）获得单链，普通ＰＡＧＥ电泳分离，经银染快速准确检出突变；应用这种方法，研究了４株鼻咽癌细胞株ＣＮＥ１，ＣＮＥ２，ＨＫ１和ＳＵＮＥ１中肿瘤抑制基因Ｐ５３基因突变，证实ＣＮＥ１，ＣＮＥ２在第８外显子，ＨＫ１在第５外显子有突变，并发现新建立的细胞株ＳＵＮＥ１存在第８外显子的突变。…”
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Chloé Thomas, Les Excentrés. Poètes modernistes américains by Clément Oudart

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A modern look at the oscillation physics case for a neutrino factory by Peter B. Denton, Julia Gehrlein

“…The next generation of neutrino oscillation experiments, JUNO, DUNE, and HK, are under construction now and will collect data over the next decade and beyond. …”
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Computationally Investigate Low Velocity Hydrokinetic Turbines with Variant Systems by P. P. Gohil, V. Patel, A. U. Mehta

“…However, an average velocity of 0.5 - 1.0 m/s is reported to be available in many water streams most of the time. Hydrokinetic (HK) turbines can extract power from the flowing water in these streams. …”
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D-mannose alleviates chronic periodontitis in rats by regulating the functions of neutrophils by Xue Li, Xueting Chen, Qingyu Zhu, Pengye Zhang, Shunxue Nan, Lei Lv, Shengcai Qi

“…The results of qPCR showed that D-mannose reduced the expression levels of IL-1β (p<0.05), IL-6 (p<0.01), IL-17 (p<0.01), TNF-α (p<0.01), G-CSF (p<0.01), GM-CSF (p<0.01), TET2 (p<0.01), HK1 (p<0.01), HK2 (p<0.01), and PFKFB3 (p<0.01). …”
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抑制<italic>miR</italic>-<italic>4321</italic>减轻脓毒症相关急性肾脏损伤的作用和机制研究 by 张春敏, 陈飞燕, 杨文敏, 林永敏, 毛碧涛, 陈洁, 武志远, 梁宇峰

“…目的本研究旨在探讨抑制<italic>miR-4321</italic>在改善脓毒症相关急性肾损伤（Sepsis associated acute kidney injury， SA-AKI）中的作用和机制。方法采用RT-qPCR方法检测LPS诱导的HK2细胞模型和CLP模型小鼠肾脏组织中<italic>miR-3165</italic>、<italic>miR-4270</italic>和<italic>miR-4321</italic>的表达水平。…”
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Protective effects of Notoginsenoside R2 on reducing lipid accumulation and mitochondrial dysfunction in diabetic nephropathy through regulation of c-Src by Xieyi Guo, Liu Yang, Xiaoning An, Maofang Hu, Yilan Shen, Niansong Wang, Youhua Xu, Dingkun Gui

“…Methods In vivo models were developed using db/db mice, while in vitro models utilized HK-2 cells exposed to high glucose and palmitic acid (HGPA). …”
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Constraining Binary Mergers in Active Galactic Nuclei Disks Using the Nonobservation of Lensed Gravitational Waves by Samson H. W. Leong, Justin Janquart, Aditya Kumar Sharma, Paul Martens, Parameswaran Ajith, Otto A. Hannuksela

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Bushen Huoxue formula protects against renal fibrosis and pyroptosis in chronic kidney disease by inhibiting ROS/NLRP3-mediated inflammasome activation by Lin Liao, Pengyu Tao, Qiming Xu, Jie Chen, Weiwei Liu, Jing Hu, Jianrao Lu

“…Similarly, BSHX treatment reduced the levels of hydroxyproline, transforming growth factor-β, matrix metalloproteinase 2, and matrix metalloproteinase 9 and inactivated the Smad2/3 signaling pathway in Ang II-treated HK-2 cells. Our data also showed that treatment with BSHX reduced NLRP3 inflammasome activation and pyroptosis in Ang II-treated HK-2 cells. …”
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Selecting habitats to reintroduce the endangered species Ardisia gigantifolia (Primulaceae) based on growth and physiological traits by Rong Liu, Dan Xie, Mengling Li, Yanmei Ping, Dongmei Li, Shupeng Dong, Yongjie Yu, Jinguo Zhang, Zulin Ning

“…Compared to NX, severe shading at GLQ and HK resulted in the decrease of light energy utilization efficiency and growth parameters. …”
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Paeoniflorin alleviates sepsis-associated acute kidney injury in mice by inhibiting aerobic glycolysis through the β-catenin/c-Myc pathway by GONG Yu, LEI Jiao, ZHANG Ming

“…ELISA was used to determine the contents of serum creatinine （Scr）， neutrophil gelatinase-associated lipocalin （NGAL） and lactate， and renal contents of hexokinase 2 （HK2）， lactate dehydrogenase A （LDHA）， IL-1β and IL-18. …”
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