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Optimization of HIV drugs through MCDM technique Analytic Hierarchy Process(AHP).
Published 2025-01-01“…This study addresses the research problemof how to optimize drug design for HIV treatment using degree-based topological indices. …”
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Using a mobile application for antiretroviral therapy adherence in people living with HIV: A longitudinal pilot study
Published 2025-01-01“…Background: The success of HIV treatment hinges on consistent adherence to antiretroviral therapy (ART). …”
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Hyperglycaemia after dolutegravir-based antiretroviral treatment in people living with human immunodeficiency virus: A case series
Published 2024-12-01“…All five patients who were living with HIV either started or switched to ART with a tenofovir, lamivudine and DTG (TLD) regimen based on the latest guidelines for HIV treatment by the National Acquired Immune Deficiency Syndrome Control Organization (NACO). …”
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International Normalized Ratio (INR) Increases amongst Two Patients Living with HIV on Warfarin after Being Switched from a Nevirapine to a Dolutegravir-Based Antiretroviral Regime...
Published 2021-01-01“…With the continued promotion of dolutegravir-based HIV regimens as the preferred option for the treatment of HIV in President’s Emergency Plan for AIDS Relief (PEPFAR) supported HIV treatment programs in Africa, clinicians must be aware of the potentially life-threatening consequences of switching antiretroviral regimens. …”
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Pharmacokinetic, Pharmacogenetic, and Other Factors Influencing CNS Penetration of Antiretrovirals
Published 2016-01-01“…While antiretroviral (ARV) drugs are the cornerstone of HIV treatment and typically produce neurological benefit, some ARV drugs have limited CNS penetration while others have been associated with neurotoxicity. …”
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The role of genetic diversity, epigenetic regulation, and sex-based differences in HIV cure research: a comprehensive review
Published 2025-01-01“…Abstract Despite significant advances in HIV treatment, a definitive cure remains elusive. The first-in-human clinical trial of Excision BioTherapeutics’ CRISPR-based HIV cure, EBT-101, demonstrated safety but failed to prevent viral rebound. …”
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A simple tool to evaluate the effectiveness of HIV care for settings with gaps in data availability (ESTIHIV).
Published 2025-01-01“…Many HIV clinics with poor IT-infrastructure are unable to report data on individuals in care with HIV, on antiretroviral treatment (ART) and virologically suppressed (VS), with the aim of monitoring the HIV Continuum of Care to estimate efficacy of HIV treatment programmes. We developed an estimation-tool, ESTIHIV, and determined the minimal data required for a random sample, to produce representative estimates, with a specified level of precision, of people with HIV on ART and VS. …”
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Early Infant Diagnosis Sample Management in Mashonaland West Province, Zimbabwe, 2017
Published 2018-01-01“…EID is the entry point to HIV treatment services in exposed infants. We determined reasons for DBS sample rejections and suggested solutions. …”
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Evaluation of a Smoking Cessation Program for HIV Infected Individuals in an Urban HIV Clinic: Challenges and Lessons Learned
Published 2014-01-01“…A low-intensity smoking cessation intervention in an HIV treatment setting is effective in a minority of participants. …”
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Entry, Retention, and Virological Suppression in an HIV Cohort Study in India: Description of the Cascade of Care and Implications for Reducing HIV-Related Mortality in Low- and Mi...
Published 2013-01-01“…HIV treatment, care, and support programmes in low- and middle-income countries have traditionally focused more on patients remaining in care after the initiation of antiretroviral therapy (ART) than on earlier stages of care. …”
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Evaluating Adherence to Antiretroviral Therapy Using Pharmacy Refill Records in a Rural Treatment Site in South Africa
Published 2017-01-01“…Optimal adherence to combination antiretroviral therapy (cART) is critical to maintain virologic suppression, thereby ensuring the global success of HIV treatment. We evaluated adherence to cART using pharmacy refill records and determined the adherence threshold resulting in >90% virologic suppression in a community run treatment site in South Africa. …”
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Daily struggle to take antiretrovirals: a qualitative study in Papuans living with HIV and their healthcare providers
Published 2020-09-01“…The findings are important in refining HIV treatment strategies implemented in Papua, especially when extending HIV care provided by community centres.Conclusions Despite free access to ART, Papuans living with HIV struggle to remain on treatment. …”
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Low levels of Plasmodium falciparum parasitaemia among patients receiving antiretroviral therapy at the treatment centre of the Regional Hospital Bamenda, Northwest Cameroon.
Published 2025-01-01“…A pre-tested questionnaire was used to collect data on participants' socio-demographic characteristics, clinical manifestations, history of HIV treatment and malaria prevention methods. Microscopy was used for malaria parasite diagnosis and to determine white blood cell (WBC) count. …”
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Virological outcomes of antiretroviral therapy and its determinants among HIV patients in Ethiopia: Implications for achieving the 95-95-95 target.
Published 2025-01-01“…<h4>Background</h4>Despite significant advancements in HIV treatment, virological outcomes remain a critical issue. …”
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Anemia among HIV-Infected Patients Initiating Antiretroviral Therapy in South Africa: Improvement in Hemoglobin regardless of Degree of Immunosuppression and the Initiating ART Re...
Published 2013-01-01“…Understanding the role of anemia in HIV treatment is critical to developing strategies to reduce morbidity and mortality. …”
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Bypassing primary antiretroviral therapy centres in Sub-Saharan Africa: An integrative review of the theoretical and empirical literature
Published 2024-12-01“…The uptake of antiretroviral therapy (ART) is critical to meeting the global HIV treatment goal of 95-95-95 by 2025. Although a few Sub-Saharan African countries have already achieved this target, the prevalence of bypassing primary ART centres in many countries in the subregion has negative implications for ART uptake and use. …”
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Mathematical analysis of the transmission dynamics of HIV/TB coinfection in the presence of treatment
Published 2007-12-01“…The analysis of the respective reproduction thresholds shows thatthe use of a targeted HIV treatment (using anti-retroviral drugs) strategy canlead to effective control of HIV provided it reduces the relative infectiousnessof individuals treated (in comparison to untreated HIV-infected individuals)below a certain threshold. …”
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Factors associated with adherence to antiretroviral therapy among HIV-positive adolescents and young adult patients attending HIV care and treatment clinic at Bombo Hospital in Tan...
Published 2025-01-01“…<h4>Background</h4>Adherence to HIV treatment regimens involves the consistent and correct intake of all prescribed medications. …”
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Underweight and its associated factors among reproductive age women on antiretroviral therapy in selected public health facilities of Arsi Zone, South East Ethiopia
Published 2025-03-01“…Background: Despite progress in HIV treatment, the reproductive age group continues to experience high rates of underweight, which adversely affects their health and ART effectiveness. …”
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Perceived neighborhood disorder and achieving HIV viral suppression among adults living with HIV: A cross-sectional study.
Published 2024-01-01“…This indicates that improving HIV treatment outcomes needs to extend beyond individual-level factors and include strategies to address neighborhood-level conditions. …”
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