CD8+ T-Cell Responses before and after Structured Treatment Interruption in Ugandan Adults Who Initiated ART with CD4+ T Cells <200 Cell/μL: The DART Trial STI Substudy by Jennifer Serwanga, Susan Mugaba, Auma Betty, Edward Pimego, Sarah Walker, Paula Munderi, Charles Gilks, Frances Gotch, Heiner Grosskurth, Pontiano Kaleebu

“…To better understand attributes of ART-associated HIV-induced T-cell responses that might be therapeutically harnessed. …”
Get full text

Early empiric anti-Mycobacterium tuberculosis therapy for sepsis in sub-Saharan Africa: a protocol of a randomised clinical trial by Mark Conaway, David R Boulware, Scott K Heysell, Stellah G Mpagama, Christopher C Moore, Alphonce Liyoyo, Conrad Muzoora, Catherine Gitige, Bibie Said, Edwin Nuwagira, Rinah Arinaitwe, Rhina Mushagara, Peter Buzaare, Anna Chongolo, Samuel Jjunju, Precious Twesigye, Megan Null, Tania A Thomas

“…Introduction Sub-Saharan Africa shoulders the highest burden of global sepsis and associated mortality. In high HIV and tuberculosis (TB) prevalent settings such as sub-Saharan Africa, TB is the leading cause of sepsis. …”
Get full text

Ascertainment and Verification of End-Stage Renal Disease and End-Stage Liver Disease in the North American AIDS Cohort Collaboration on Research and Design by Mari M. Kitahata, Daniel R. Drozd, Heidi M. Crane, Stephen E. Van Rompaey, Keri N. Althoff, Stephen J. Gange, Marina B. Klein, Gregory M. Lucas, Alison G. Abraham, Vincent Lo Re, Justin McReynolds, William B. Lober, Adell Mendes, Sharada P. Modur, Yuezhou Jing, Elizabeth J. Morton, Margaret A. Griffith, Aimee M. Freeman, Richard D. Moore

“…The burden of HIV disease has shifted from traditional AIDS-defining illnesses to serious non-AIDS-defining comorbid conditions. …”
Get full text

Visual Mapping of Operating Theater Team Dynamics and Communication for Reflexive Feedback and Surgical Practice Optimization by Surya Surendran, MA, Candice Bonaconsa, MSc, Vrinda Nampoothiri, PharmD, Oluchi Mbamalu, PhD, Anu George, PGDip, Swetha Mallick, MCh, Sudheer OV, MCh, Alison Holmes, MD, Marc Mendelson, PhD, Sanjeev Singh, PhD, Gabriel Birgand, PhD, Esmita Charani, PhD

Get full text

Late Onset Combined Immunodeficiency Presenting with Recurrent Pneumocystis jiroveci Pneumonia by Ilias Papakonstantinou, Ioannis G. Baraboutis, Lazaros Karnesis

“…Clinicians should be aware of LOCID, which could be confused with HIV infection/AIDS or idiopathic CD4 lymphocytopenia. …”
Get full text

A New Generalized Fractional-Order Derivative and Bifurcation Analysis of Cholera and Human Immunodeficiency Co-Infection Dynamic Transmission by Kumama Regassa Cheneke, Koya Purnachandra Rao, Gereme Kenassa Edesssa

“…In this study, the co-infection of HIV and cholera model has been developed and analyzed. …”
Get full text

Towards Inhibition of Vif-APOBEC3G Interaction: Which Protein to Target? by Iris Cadima-Couto, Joao Goncalves

“…APOBEC proteins appeared in the cellular battle against HIV-1 as part of intrinsic cellular immunity. The antiretroviral activity of some of these proteins is overtaken by the action of HIV-1 Viral Infectivity Factor (Vif) protein. …”
Get full text

A Rare Occurrence of Primary Hepatic Leiomyosarcoma Associated with Epstein Barr Virus Infection in an AIDs Patient by Haritha Chelimilla, Kanthi Badipatla, Ariyo Ihimoyan, Masooma Niazi

“…We herein present a case report of a 54-year-old man diagnosed to have HIV/AIDS and EBV infection admitted to our hospital with complaints of intractable hiccups for more than a week. …”
Get full text

Chickenpox pneumonia. Case presentation. Dora Ngiza hospital, Port Elizabeth, South Africa. by Gilberto Serrano Ocaña, Juan Carlos Ortiz Sablon, Ilen Ochoa Tamayo

“…In this article we describe a case of chickenpox in a young HIV positive patient complicated with Varicella-Zoster pneumonia. …”
Get full text

Primary Esophageal Lymphoma: A Histopathological Experience from Two Tertiary Hospitals, Western Saudi Arabia by Jaudah Al-Maghrabi, Sahar Al-Maghrabi

“…There was no relation to immune status or HIV infection in this series. Clinical presentations were typically dysphagia with weight loss. …”
Get full text

Systematic review of reviews on interventions to engage men and boys as clients, partners and agents of change for improved sexual and reproductive health and rights by Sanyukta Mathur, Julie Pulerwitz, Ann Gottert, Jesse Werner, Renay Weiner, Chantalle Okondo, Sarah Magni

“…Objectives Evidence regarding interventions to engage men and boys to improve sexual and reproductive health and rights (SRHR) has grown rapidly across subtopics such as HIV, family planning and gender-based violence (GBV). …”
Get full text

Qualitative focus group discussions exploring PrEP method and service delivery preferences among female sex workers and their managers in four Zambian provinces by Holly M Burke, Emily Evens, Tendai Munthali, Featherstone Mangunje, Mercy L Kotaka, Bupe Musonda, Musonda Musonda, Catherine S Todd

“…Among potential future HIV prevention options, most FSWs preferred longer acting PrEP methods, mainly CAB PrEP over the PrEP ring. …”
Get full text

Navigating DR-TB Treatment care: a qualitative exploration of barriers and facilitators to retention in care among people with history of early disengagement from drug-resistant tu... by Ndiviwe Mphothulo, Sindisiwe Hlangu, Jennifer Furin, Mosa Moshabela, Marian Loveday

Get full text

Acceptability of a dapivirine levonorgestrel vaginal ring in two Phase 1 trials (MTN-030/IPM 041 and MTN-044/IPM 053/CCN019): Implications for multipurpose prevention technology de... by Barbara A Friedland, Holly Gundacker, Sharon L Achilles, Beatrice A Chen, Craig Hoesley, Barbra A Richardson, Clifton W Kelly, Jeanna Piper, Sherri Johnson, Brid Devlin, John Steytler, Kyle Kleinbeck, Bindi Dangi, Chantél Friend, Mei Song, Barbara Mensch, Ariane van der Straten, Cindy Jacobson, Craig W Hendrix, Jill Brown, Diana Blithe, Sharon L Hiller, MTN-030/IPM 041 and MTN-044/IPM 053/CCN019 Protocol Teams for the Microbicide Trials Network and the Contraceptive Clinical Trials Network

“…We enrolled healthy, non-pregnant, HIV-negative women aged 18-45 in Pittsburgh, PA and Birmingham, AL (MTN-030 only). …”
Get full text

Gym exercising patterns, lifestyle and high-risk sexual behaviour in men who have sex with men and in heterosexual men by N Davidovitch, Z Mor, K Parfionov, I Grotto

“…The gym MSM culture demonstrates how internal dynamics and social norms are possible factors driving MSM to high-risk behaviour for HIV/STI.Study registration The study was approved by the Wolfson Hospital Review Board, Holon, Israel (WOMC-0058-09).…”
Get full text

Exploring pre-exposure prophylaxis (PrEP) modality preferences among black cisgender women attending family planning clinics in Chicago via a cross-sectional mixed-methods study by Sadia Haider, Amy K Johnson, Emily Ott, Eleanor E Friedman, Agustina Pandiani, Amy Moore, Isa Alvarez, Catherine Desmarais

“…Background Despite pre-exposure prophylaxis (PrEP) demonstrated effectiveness, black cisgender women continue to be at an elevated risk for HIV acquisition and uptake of daily oral PrEP is low in this population in the USA. …”
Get full text

Anemia among Women Attending Antenatal Care at the University of Gondar Comprehensive Specialized Referral Hospital, Northwest Ethiopia, 2017 by Wubet Worku Takele, Amare Tariku, Fasil Wagnew Shiferaw, Amare Demsie, Wondale Getinet Alemu, Degefaye Zelalem Anlay

“…Human Immunodeficiency Virus (HIV) screening was conducted. Nutritional status of the participants was assessed. …”
Get full text

The Determinants of Sexual Intercourse Before Age 16 Years Among Rural Jamaican Adolescents by Olaniyi J. Ekundayo, Joana Dodson-Stallworth, Michele Roofe, Inmaculada B. Aban, Laura H. Bachmann, Mirjam C. Kempf, John Ehiri, Pauline E. Jolly

“…Considering the high rates of HIV and adolescent pregnancy in this population, reproductive health programs that attempt to delay age at first sex should begin early in primary school before adolescents become sexually active.…”
Get full text

Determinants of Higher-Risk Sexual Behavior in Some Selected African Countries by Adikwor Ewoenam Puplampu, Seth Afagbedzi, Samuel Dery, Dzifa Adimle Puplampu, Chris Guure

“…Although higher-risk sexual behavior (H-RSB) is a major contributor to the rapid rising rate of new HIV infections, there exists paucity of comprehensive evidence across the sub-Saharan African region. …”
Get full text

Suspected Mpox Symptoms and Testing in Men Who Have Sex With Men in the United States: Cross-Sectional Study by Kaitlyn Atkins, Thomas Carpino, Amrita Rao, Travis Sanchez, O Winslow Edwards, Marissa Hannah, Patrick S Sullivan, Yasmin P Ogale, Winston E Abara, Kevin P Delaney, Stefan D Baral

“…Of those tested, 3 reported living with HIV and all were on treatment, whereas the remaining 6 men without HIV reported current pre-exposure prophylaxis (PrEP) use. …”
Get full text