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Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection
Published 2025-01-01“…Purine metabolism was also enriched in H3N2 patients compared to H1N1, with increased xanthine, deoxyguanosine, and inosine. …”
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The Development of a Novel Broad-Spectrum Influenza Polypeptide Vaccine Based on Multi-Epitope Tandem Sequences
Published 2025-01-01“…Protective efficacy was evaluated using viral challenge with lethal doses of H1N1 and H7N9. Results: Mice immunized with P125-H generated high levels of HI and neutralizing antibodies against multiple influenza strains. …”
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63
Preface
Published 2010-12-01“…A new A/H1N1 influenza virus strain was officially reported/identified in Mexico City on April 13 2009 and over a period of two-weeks the WHO pandemic alert was moved from level 3 to level 5. …”
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Adjuvant-free, self−assembling ferritin nanoparticle vaccine coupled with influenza virus hemagglutinin protein carrying M1 and PADRE epitopes elicits cross-protective immune respo...
Published 2025-01-01“…And neutralization titers induced by HMP-NPs against the H3N2 virus and heterologous strains of the H1N1 and H9N2 viruses were ~8, 12.4 and 16 times higher than inactivated influenza vaccine, respectively. …”
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A Near-Fatal Infection with Oseltamivir-Resistant Seasonal Influenza A in a Previously Healthy Child: Case Report
Published 2009-01-01“…This case highlights three important points for physicians: oseltamivir-resistant influenza A (H1N1) has recently emerged in North America; contrary to previously held beliefs, such strains are capable of causing severe disease in healthy children; and given this change in epidemiology, clinicians caring for children with severe seasonal influenza A infection should consider empiric dual therapy with oseltamivir and amantadine.…”
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66
A Review of Methods Applied to Study Airborne Biocontaminants inside Aircraft Cabins
Published 2011-01-01“…Indoor-cross infection of expiratory contaminants is still a concern, worsened by the SARS outbreak in 2003 and recent cases of influenza strains (H1N1, avian flu, etc.). A variety of methods to study the airborne spread of expiratory contaminants have been worked out, including the use of tracer gas, particle generators, and CFD simulations. …”
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Endothelial activation and dysfunction caused by influenza A virus (<i>Alphainfluenzavirus influenzae</i>)
Published 2024-12-01“…Thus, influenza A viruses, including subtypes A(H1N1)pdm09, A(H3N2), as well as highly pathogenic avian influenza viruses, can infect the vascular endothelium, leading to activation and subsequent dysfunction of these cells. …”
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Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease
Published 2022-11-01“… The COVID-19 pandemic has quickly become the most significant public health phenomenon, effectively eclipsing the H1N1 and Ebola crises that came before it. It can spread rapidly and has caused the death and disability of many worldwide. …”
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Modeling the impact of twitter on influenza epidemics
Published 2014-08-01“…We also perform numericalsimulations, conduct sensitivity test on a few parameters related totweets, and compare modeling predictions with surveillance data ofinfluenza-like illness reported cases and the percentage of tweetsself-reporting flu during the 2009 H1N1 flu outbreak in England andWales. These results show that social media programs like Twittermay serve as a good indicator of seasonal influenza epidemics andinfluence the emergence and spread of the disease.…”
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70
A note on the use of influenza vaccination strategies when supply is limited
Published 2010-12-01“…The 2009 A (H1N1) influenza pandemic was rather atypical. It began in North America at the start of the spring and in the following months, as it moved south, efforts to develop a vaccine that would mitigate the potential impact of a second wave were accelerated. …”
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Anthroponoses: humans infecting animals with infectious diseases
Published 2024-09-01“…The recurring classical H1N1 swine influenza virus, which is circulating even now, is a spillover from the 1918 human influenza pandemic that was introduced into the pig population. …”
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A Review of the Antiviral Susceptibility of Human and Avian Influenza Viruses over the Last Decade
Published 2014-01-01“…However, the emergence of oseltamivir-resistant seasonal A(H1N1) viruses in 2008 demonstrated that NAI-resistant viruses could also emerge and spread globally in a similar manner to that seen for adamantane-resistant viruses. …”
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Pandemic mitigation: Bringing it home
Published 2010-12-01“…We summarize here the envelope of mortality attributable to epidemic and pandemic influenza in the last 90 years of the last century as a lead in to a presentation of the multinational case age distribution of the novel H1N1 pandemic of 2009. We discuss the sparing of elderly subpopulations in pandemics and the subsequent abrupt resurgence of mortality in the spared age groups as drift variants emerge. …”
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Convalescent plasma therapy in severe coronavirus disease-2019: A narrative review
Published 2020-01-01“…It was also effective in reducing the mortality and viral load in severe acute respiratory syndrome, H5N1, H1N1, and Middle East Respiratory Syndrome. Convalescent plasma administration carries the risk of anaphylactic reactions, transfusion-related acute lung injury, and transfusion-associated circulatory overload, but these are extremely rare. …”
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Epidemic spread of influenza viruses: The impact of transient populations on disease dynamics
Published 2010-12-01“…The recent H1N1 ('swine flu') pandemic and recent H5N1 ('avian flu') outbreaks have brought increased attention to the study of the role of animal populations as reservoirs for pathogens that could invade human populations. …”
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Restoration of Type 17 immune signaling is not sufficient for protection during influenza-associated pulmonary aspergillosis
Published 2025-01-01“…In this study, we investigate the role of IL-17 and Type 17 immune signaling components during IAPA.MethodsWild-type mice were challenged with influenza A H1N1 (flu) and then exposed to Aspergillus fumigatus ATCC42202 resting conidia on day 6 post-influenza infection, followed by the quantification of cytokines and chemokines at 48 h post-fungal infection.Results and discussionThe gene and protein expression levels revealed that IL-17 and Type 17 immune cytokines and antimicrobial peptides are downregulated during IAPA compared to mice singularly infected solely with A. fumigatus. …”
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Miocarditis como expresión de lupus eritematoso sistémico. Presentación de un caso
Published 2016-12-01“…Tenía historia previa de infección respiratoria durante el periodo epidémico de la influenza H1N1, diagnosticada por neumonía con derrame cuya evolución fue tórpida. …”
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Redaktoriaus žodis
Published 2020-06-01“…Tas pats vyko ir su antrąja viruso H1N1 banga 2009-2010 metais. Taigi, kaip galėtume išvengti antrosios koronaviruso bangos? …”
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Discrete epidemic models
Published 2009-12-01“…Mostrecently, efforts to connect theoretical work to data have explodedas attempts to deal with the threat of emergent and re-emergentdiseases including the most recent H1N1 influenza pandemic, havemarched to the forefront of our global priorities. …”
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A holistic and sustainable approach to public health staffing and workforce development
Published 2025-01-01“…Public health in the United States faces a continuous cycle of “neglect, panic, repeat.” As seen with 9/11, H1N1, and COVID-19, public health emergencies create a flurry of attention and resources, but once the crisis passes, focus quickly shifts to other matters until the next emergency, when the cycle repeats. …”
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