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641
Alleviation of DSS-induced colitis by Meconopsis polysaccharides correlated with reduced PI3K/AKT signaling and gut microbiome diversity
Published 2025-02-01“…Additionally, MP promoted gut microbiota diversity and regulated SCFA concentrations, contributing to an improved intestinal microenvironment and alleviation of colitis symptoms.DiscussionOur findings highlight the superior effectiveness of Meconopsis polysaccharides in alleviating DSS-induced colitis and open new avenues for targeted therapeutic strategies in the treatment of IBD.…”
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642
The bacterial microbiome modulates the initiation of brain metastasis by impacting the gut-to-brain axis
Published 2025-02-01“…Together, these results illuminate the potential role of gut microbiota in modulating breast-BrM via the gut-to-brain axis.…”
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643
Sex Differences in the Allele Distribution of PGLYRP2 Variant rs892145 in Parkinson’s Disease
Published 2023-01-01“…The microbiota-gut-brain axis is hypothesized to play a role in the pathophysiology of PD, and peptidoglycan recognition proteins (PGLYRPs), which modulate the gut microbiota, are, therefore, relevant candidate genes for PD. …”
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644
Comprehensive analysis of the interaction microbiome and prostate cancer: an initial exploration from multi-cohort metagenome and GWAS studies
Published 2025-01-01“…We used Kraken2, a mapping tool, to mine the gut microbiota of prostate cancer patients. A two-sample Mendelian Randomization was conducted to reflect the association between gut microbiome and cancer. …”
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645
Dietary Chia (Salvia hispanica L.) seeds oil supplementation augments growth performance and gut microbial composition in Labeo rohita fingerlings
Published 2025-01-01“…Overall, the findings highlight the beneficial effects of 1.0% CSO supplementation on growth performance and modulation of gut microbiota in L. rohita fingerlings.…”
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646
Fecal occult blood affects intestinal microbial community structure in colorectal cancer
Published 2025-01-01“…Characteristic gut bacteria were screened, and various machine learning algorithms were applied to construct CRC risk prediction models. Results The gut microbiota of healthy people and CRC patients with different fecal occult blood were mapped. …”
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647
Bacterial extracellular vesicles in the initiation, progression and treatment of atherosclerosis
Published 2025-12-01“…Recent research indicates the crucial involvement of oral and gastrointestinal microbiota in atherosclerosis. While gut microbiota metabolites, such as choline derivatives, have been extensively studied and reviewed, emerging evidence suggests that bacterial extracellular vesicles (BEVs), which are membrane-derived lipid bilayers secreted by bacteria, also play a significant role in this process. …”
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648
Effects of Red Clover Isoflavones on Growth Performance, Immune Function, and Cecal Microflora of Mice
Published 2025-01-01“…We hypothesize that red clover isoflavones (RCIs) achieve health-promoting effects via altering the gut microbiota. A total of 48 mice (20 ± 2 g) were randomly divided into a control group, low-dose group (0.05% RCIs in feed), middle-dose group (0.1% RCIs in feed), and high-dose group (0.2% RCIs in feed) with 12 mice per group. …”
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649
Effect of fermented bee pollen on metabolic syndrome in high-fat diet-induced mice
Published 2021-05-01“…Overall, YB improved function and prevented MetS by modulating the gut microbiota and alleviating oxidative stress.…”
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650
Improvement of Fish Growth and Metabolism by Oligosaccharide Prebiotic Supplement
Published 2022-01-01“…These improvements were associated with significant changes in the fish gut microbiota. The abundance of Clostridium ruminantium, Brevinema andersonii, Shewanella amazonensis, Reyranella massiliensis, and Chitinilyticum aquatile were upregulated by XOS and GOS supplements. …”
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651
Peripheral Signals Mediate the Beneficial Effects of Gastric Surgery in Obesity
Published 2015-01-01“…In fact, bariatric surgery modifies the production of both gastrointestinal and adipose tissue peripheral signals beyond the gut microbiota composition. Through this paper the main peripheral signals altered in obesity will be reviewed together with their modifications after bariatric surgery.…”
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652
Microbial diversity and biogeography across gastrointestinal tracts of Takifugu pufferfish revealed by full-length 16S amplicon sequencing
Published 2025-01-01“…Our findings reveal a compositional and functional biogeography of pufferfish gut microbiota along the GIT and between host genetics. …”
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653
Diabetes Mellitus and Increased Tuberculosis Susceptibility: The Role of Short-Chain Fatty Acids
Published 2016-01-01“…Alteration of the gut microbiota, thereby increasing butyrate concentrations, can reduce insulin resistance and obesity, but further studies are needed to determine how this affects susceptibility to tuberculosis.…”
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654
Liver Microbiome in Healthy Rats: The Hidden Inhabitants of Hepatocytes
Published 2023-01-01“…Herein, we report that microbiota were detected in high abundance in the hepatocytes of healthy rats and that they were shared with the gut microbiota to an extent. We assessed male Sprague Dawley (SD) rats for the 16S ribosomal ribonucleic acid (rRNA) gene. …”
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655
Clostridium butyricum attenuates LPS-induced myocardial injury in septic mice by modulating CD4 + CD25 + FOXP3 + Treg
Published 2025-01-01“…Significant changes were noted in the gut microbiota of the mice, highlighting that C. butyricum can positively influence the immune state in septic myocardial injury models. …”
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656
Characterization and comparison of fecal microbiota in horses with pituitary pars intermedia dysfunction and age‐matched controls
Published 2025-01-01“…Abstract Background Altered gut microbiota has been associated with dopaminergic degenerative diseases in people, but studies on horses with pituitary pars intermedia dysfunction (PPID) are lacking. …”
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657
Synbiotics effects of d-tagatose and Lactobacillus rhamnosus GG on the inflammation and oxidative stress reaction of Gallus gallus based on the genus of cecal bacteria and their me...
Published 2025-01-01“…Treat Gallus gallus exhibiting oxidative stress and immune response caused by aflatoxin b1 with optimal synbiotics for 14 days, detect the changes of inflammatory markers and oxidative stress markers of Gallus gallus using qRT-PCR, and identified the intestinal bacteria genera and their metabolites in the cecum of Gallus gallus using gut microbiota and metabolomics analysis.<h4>Results and conclusion</h4>The results indicated that oxidative stress and immune response factor expressions quantity in Gallus gallus decreased significantly after 14 days of treatment, compared with model group, the low-dose treatment group's SOD1, SOD3, GPX1, GPX2, GSR, H6DP, and HO-1 genes in liver were downregulated by 36.03%, 40.01%, 45.86%, 40.79%, 37.68%, 25.04%, and 29.89%, the IL-1, IL-2, IL-4, IL-6, IgA, IgM, and IgG genes in blood and spleen were downregulated by 26.59%, 34.19%, 21.19%, 28.18%, 35.93%, 12.67%, 21.81 and 35.93%, 22.85%, 21.19%, 28.78%, 35.93%, 15.36%, 29.73%. …”
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658
Roles of fermented plant-, dairy- and meat-based foods in the modulation of allergic responses
Published 2023-05-01“…Positive outcomes on AR through fermented foods could be linked to microbial hydrolysis of food allergens, improvement in gut microbiota robustness, and modulation of the immune system that promotes a balance between T helper 1 (Th1) and Th2 cells. …”
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659
Microbial signatures in head and neck squamous cell carcinoma: an in silico study
Published 2025-02-01“…Dysbiosis of oral and gut microbiota is associated with several oral and systemic pathologies, such as cancer, obesity, diabetes, atherosclerosis and gastrointestinal diseases. …”
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660
Emodin Ameliorates Intestinal Dysfunction by Maintaining Intestinal Barrier Integrity and Modulating the Microbiota in Septic Mice
Published 2022-01-01“…Bioinformatic analysis based on 16s rRNA gene sequencing illustrated that emodin treatment significantly increased the alpha- and beta-diversity of gut microbiota in septic mice. Moreover, data according to functional prediction showed that emodin decreased the abundance of potential pathogenic bacteria in gut. …”
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