Beta-Defensin-2 and Beta-Defensin-3 Reduce Intestinal Damage Caused by Salmonella typhimurium Modulating the Expression of Cytokines and Enhancing the Probiotic Activity of Enteroc... by Alessandra Fusco, Vittoria Savio, Marcella Cammarota, Alberto Alfano, Chiara Schiraldi, Giovanna Donnarumma

“…Based on the literature data, the purpose of this work was to create a line of intestinal epithelial cells able to stably express gene encoding human β-defensin-2 (hBD-2) and human β-defensin-3 (hBD-3), in order to test their role in S. typhimurium infections and their interaction with the bacteria of the gut microbiota.…”
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New Insights into the Mechanisms of Chinese Herbal Products on Diabetes: A Focus on the “Bacteria-Mucosal Immunity-Inflammation-Diabetes” Axis by Zezheng Gao, Qingwei Li, Xuemin Wu, Xuemin Zhao, Linhua Zhao, Xiaolin Tong

“…Here, we have proposed that many herbal monomers and formulae improve glucose homeostasis and diabetes through the BMID axis; B represents gut microbiota, M means mucosal immunity, I represents inflammation, and D represents diabetes. …”
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The Relationship among Physical Activity, Intestinal Flora, and Cardiovascular Disease by Qiuyu Yan, Wenhui Zhai, Chenghao Yang, Zihao Li, Longfei Mao, Mingyi Zhao, Xiushan Wu

“…PA benefits the metabolic changes that occur in the gut microbiota (GM). The major metabolites of the GM influence pathogenesis of CVDs through various pathways. …”
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Faecalibacterium prausnitzii: A Next-Generation Probiotic in Gut Disease Improvement by Xiaoya He, Shuyang Zhao, Yan Li

“…Thus, for reshaping ecological balance, a growing body of the literatures have proposed numerous strategies to modulate the structure of the gut microbiota, which provide more revelation for amelioration of these inflammation or infection-related diseases. …”
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Interaction studies unveil potential binding sites on bovine serum albumin for gut metabolite trimethylamine n-oxide (TMAO) by Awadhesh Kumar Verma, Payal Gulati, GBVS Lakshmi, Anand Mohan, Neeta Raj Sharma, Pratima R. Solanki, Anil Kumar

“…Abstract Trimethylamine-N-oxide (TMAO) is gut microbiota-derived metabolite, plays a critical role in human health and diseases such as metabolic, cardiovascular, colorectal cancer and, neurological disorders. …”
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Digging deeper into necrotizing enterocolitis: bridging clinical, microbial, and molecular perspectives by Deshuang Zhang, Dongke Xie, Yi Qu, Dezhi Mu, Shaopu Wang

“…We further critically examine dysbiotic alterations within the gut microbiota, with a particular focus on imbalances in bacterial and viral communities, which may contribute to the onset of NEC. …”
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Gut Microbiome Profiles in Colorectal Cancer Patients in Iraq by Fatima J. Kadhim, Zahid S. Aziz, Khalid S. Ibrahim

“…This study aims to investigate the differences in gut microbiota between CRC patients and healthy individuals in Iraq, using 16S rRNA metagenomic sequencing on Illumina NovaSeq (PE250-Seq). …”
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Nonpharmacological Modulation of Chronic Inflammation in Parkinson’s Disease: Role of Diet Interventions by Stefania Kalampokini, Anouck Becker, Klaus Fassbender, Epameinondas Lyros, Marcus M. Unger

“…Food-based therapies may favorably modulate gut microbiota composition and enhance the intestinal epithelial integrity or decrease the proinflammatory response by direct effects on immune cells. …”
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2′-Fucosyllactose as a prebiotic modulates the probiotic responses of Bifidobacterium bifidum by Jingfang Du, Hong Yang

“…These observations provide a useful guideline for developing synbiotic supplements to intervene the infant gut microbiota.…”
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Intrathecal Immunoglobulin A Synthesis in Multiple Sclerosis: From Biological Aspects to Clinical Relevance by Dariia Kliushnikova, Ferdinand Otto, Georg Pilz, Peter Wipfler, Andrea Harrer

“…A connection between intrathecal IgA synthesis and the gut–brain axis in MS was further corroborated by the discovery of gut microbiota-specific IgA+ B cells in human CNS during relapse. …”
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Diversity and Species Composition of Midgut Symbiotic Bacteria in Culex quinquefasciatus Mosquitoes in Gampaha District, Sri Lanka by Randi Hathnagoda, Pinidi Gunathilake, Thilini Buddhinee, Pabasara Welgama, Hasini Gunarathna, Harshani Perera, Koshila Ranasinghe

“…The present study focuses on the importance of understanding mosquito gut microbiota for implementing innovative vector control strategies, thereby mitigating disease transmission. …”
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Evaluation of Faecal Microbiota Following Probiotics in Infants of Mothers with Gestational Diabetes Mellitus Trial: Protocol for Double-Blind Placebo-Controlled Randomized Trial by Gayatri Athalye-Jape, Chandra Prakash Rath, Harshad Panchal, Archita Mishra, Dorothy Graham, Sanjay Patole

“…The current evidence indicates that GDM, especially in conjunction with maternal overweight, can alter the composition of infants’ gut microbiota, potentially increasing the risk of inflammatory diseases, metabolic disorders, and neurodevelopmental issues later in life. …”
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Research update on the effects of probiotic supplementation during pregnancy on pregnancy complications: a systematic literature review by Jing YANG, Xiaochuan WANG, Borui LIU, Xiaoyan ZHANG, Xiaoyu GAO, Jiajin HU

“…As modulators of gut microbiota, probiotics possess anti-inflammatory and immunomodulatory properties, potentially offering benefits in preventing pregnancy complications and improving clinical symptoms. …”
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Role of Probiotics in the Management of Patients with Ulcerative Colitis and Pouchitis by Francesca Bernardi, Fabrizio Fanizzi, Tommaso Lorenzo Parigi, Alessandra Zilli, Mariangela Allocca, Federica Furfaro, Laurent Peyrin-Biroulet, Silvio Danese, Ferdinando D’Amico

“…The development of pouchitis is closely linked to dysbiosis—an imbalance in the gut microbiota. Understanding the role of the microbiota in pouch health has spurred interest in probiotics as a therapeutic strategy. …”
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Diet and medical foods in Parkinson’s disease by Klaus W. Lange, Yukiko Nakamura, Ning Chen, Jianjun Guo, Shigehiko Kanaya, Katharina M. Lange, Shiming Li

“…Interventions targeting gut microbiota, such as the supplementation of probiotics, may provide novel approaches to PD in regard to both symptomatic treatment and disease modification. …”
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Optimization of Poultry Physiological Condition in the Post-Antibiotic Era through Nutritional Intervention – A Review by Sugiharto Sugiharto, Muhammad Asif Raza

“…Nutritional intervention can be used to enhance the equilibrium of the gut microbiota in chickens, leading to good physiological effects. …”
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Gut Dysbiosis and Muscle Aging: Searching for Novel Targets against Sarcopenia by Anna Picca, Francesca Fanelli, Riccardo Calvani, Giuseppina Mulè, Vito Pesce, Alex Sisto, Cecilia Pantanelli, Roberto Bernabei, Francesco Landi, Emanuele Marzetti

“…Interestingly, imbalanced intestinal microbial community has been suggested to contribute to inflammaging. Changes in gut microbiota accompanying sarcopenia may be attenuated by supplementation with pre- and probiotics. …”
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Bacteria Load Determination of the Intestinal Microbiota and Identification of Spiroplasma and Wolbachia in Anopheles gambiae by Haziz Sina, Kamirou Chabi-Sika, Razaki Ossè, Akim Socohou, Ibrahim A. Abibou, Hafiz Salami, Germain Gil Padonou, Adolphe Adjanonhoun, Lamine Baba-Moussa

“…The gut microbiota of mosquitoes is composed of a range of microorganisms. …”
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Mechanistic relationship between obesity-induced inflammation triggering endothelial dysfunction and the initiation of atherosclerosis development by Richard L. Jayaraj, Elhadi H Aburawi

“…The aim of this review is to summarize the effects of obesity-related inflammation on ED and its progression to atherosclerosis, focusing on cellular senescence, vascular aging, epigenetic modifications, reactive oxygen species, vascular calcification, and gut microbiota. In addition, we are also exploring new therapeutic strategies to reverse ED to prevent CVD and MD. …”
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Predicting metabolite response to dietary intervention using deep learning by Tong Wang, Hannah D. Holscher, Sergei Maslov, Frank B. Hu, Scott T. Weiss, Yang-Yu Liu

“…In particular, the gut microbiota, a collection of trillions of microorganisms living in the gastrointestinal tract, is highly personalized and plays a key role in the metabolite responses to foods and nutrients. …”
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